Page last updated: 2024-08-17

quinidine and uk 68798

quinidine has been researched along with uk 68798 in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	8 (18.18)	18.2507
2000's	18 (40.91)	29.6817
2010's	15 (34.09)	24.3611
2020's	3 (6.82)	2.80

Authors

Authors	Studies
Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE	1
Topliss, JG; Yoshida, F	1
Keserü, GM	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Gwilt, M; King, RC; Milne, AA; Solca, AM	1
Roden, DM; Yang, T	1
Cha, Y; Feld, GK; Sawhney, N; Shahrokni, S; Wales, A; Wolf, P	1
Olshansky, B	1
Bursill, JA; Campbell, TJ; Wyse, KR	1
Roden, DM; Snyders, DJ; Yang, T	2
Duan, Y; Duff, HJ; Lees-Miller, JP; Teng, GQ	1
De Clerck, F; Lu, HR; Mariën, R; Saels, A	1
Caballero, R; Chartier, D; Hébert, TE; Nattel, S; Weerapura, M	1
Bhatta, L; Hynes, J; Khan, M; Luck, J; Naccarelli, GV; Samii, S; Wolbrette, DL	1
Kao, W; Kowey, PR; Winkel, E; Yan, GX	1
Dong, DL; Du, ZM; Li, Z; Song, WH; Wang, HZ; Yang, BF	1
Dong, DL; Du, ZM; Li, Z; Wang, HZ; Xu, CQ; Xu, DH; Yang, BF	1
Kurachi, Y; Suzuki, S; Tsujimae, K; Yamada, M	1
Cvetanovic, I; Ke, X; Lin, C; Ranade, V; Somberg, J	1
Hamlin, RL; Keene, BW; Kijtawornrat, A; Nishijima, Y; Roche, BM	1
Cox, BF; Gintant, GA; Limberis, JT; Martin, RL; Su, Z	1
Hamlin, RL; Kijtawornrat, A; Sawangkoon, S	1
Florian, J; Galeotti, L; Guo, P; Hong, M; Johannesen, L; Lin, J; Mason, JW; Sanabria, C; Stockbridge, N; Strauss, DG; Sørensen, JS; Ugander, M; Vicente, J; Waite-Labott, K	1
Haigney, MC	1
Crumb, WJ; Johannesen, L; Mason, JW; Pueyo, E; Stockbridge, N; Strauss, DG; Vicente, J	1
Hamlin, RL; Kijtawornrat, A; Limprasutr, V; Meedech, P; Saengklub, N	1
Osadchii, OE	3
Shen, C; Stabenau, HF; Tereshchenko, LG; Waks, JW	1
Bai, S; Cao, H; Chen, K; Dong, H; Ma, Y; Pei, J; Tian, L; Zhao, Y	1

Reviews

4 review(s) available for quinidine and uk 68798

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Dofetilide versus quinidine for atrial flutter: viva la difference!? Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:9 Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Phenethylamines; Quinidine; Sulfonamides	1996
Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Australia; Canada; Controlled Clinical Trials as Topic; Europe; Flecainide; Heart Conduction System; Heart Failure; Humans; Multicenter Studies as Topic; Myocardial Infarction; Phenethylamines; Propafenone; Quinidine; Sotalol; Sulfonamides; Survival Analysis; Therapeutic Equivalency; Treatment Outcome; United States	2003
Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Flecainide; Heart Rate; Humans; Phenethylamines; Practice Guidelines as Topic; Propafenone; Quinidine; Stroke; Sulfonamides; Ventricular Dysfunction, Left	2003

Trials

2 trial(s) available for quinidine and uk 68798

Article	Year
Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil. Clinical pharmacology and therapeutics, 2014, Volume: 96, Issue:5 Topics: Acetanilides; Calcium Channel Blockers; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart Rate; Humans; Phenethylamines; Piperazines; Potassium Channel Blockers; Prospective Studies; Quinidine; Ranolazine; Sodium Channel Blockers; Sulfonamides; Verapamil	2014
Comprehensive T wave morphology assessment in a randomized clinical study of dofetilide, quinidine, ranolazine, and verapamil. Journal of the American Heart Association, 2015, Apr-13, Volume: 4, Issue:4 Topics: Adult; Calcium Channel Blockers; Cross-Over Studies; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Heart; Humans; Long QT Syndrome; Male; Phenethylamines; Quinidine; Ranolazine; Sodium Channel Blockers; Sulfonamides; Verapamil	2015

Article

Year

Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.

Clinical pharmacology and therapeutics, 2014, Volume: 96, Issue:5

Topics: Acetanilides; Calcium Channel Blockers; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart Rate; Humans; Phenethylamines; Piperazines; Potassium Channel Blockers; Prospective Studies; Quinidine; Ranolazine; Sodium Channel Blockers; Sulfonamides; Verapamil

2014

Comprehensive T wave morphology assessment in a randomized clinical study of dofetilide, quinidine, ranolazine, and verapamil.

Journal of the American Heart Association, 2015, Apr-13, Volume: 4, Issue:4

Topics: Adult; Calcium Channel Blockers; Cross-Over Studies; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Heart; Humans; Long QT Syndrome; Male; Phenethylamines; Quinidine; Ranolazine; Sodium Channel Blockers; Sulfonamides; Verapamil

2015

Other Studies

38 other study(ies) available for quinidine and uk 68798

Article	Year
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents. Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship	1993
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation. European journal of medicinal chemistry, 2008, Volume: 43, Issue:11 Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Dofetilide, a new class III antiarrhythmic agent, reduces pacing induced heterogeneity of repolarisation in vivo. Cardiovascular research, 1992, Volume: 26, Issue:11 Topics: Animals; Anti-Arrhythmia Agents; Dogs; Electrocardiography; Electrophysiology; Heart Rate; Phenethylamines; Quinidine; Sulfonamides; Ventricular Function	1992
Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence. Circulation, 1996, Feb-01, Volume: 93, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Electrophysiology; Extracellular Space; Heart; Humans; Mice; Myocardium; Phenethylamines; Potassium; Quinidine; Sulfonamides; Torsades de Pointes	1996
Electrophysiologic effects of the new class III antiarrhythmic drug dofetilide compared to the class IA antiarrhythmic drug quinidine in experimental canine atrial flutter: role of dispersion of refractoriness in antiarrhythmic efficacy. Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:9 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Flutter; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction System; Phenethylamines; Quinidine; Sulfonamides; Treatment Outcome	1996
Differential effects of antiarrhythmic agents on post-pause repolarization in cardiac Purkinje fibres. Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:9 Topics: Action Potentials; Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Dose-Response Relationship, Drug; Phenethylamines; Potassium Channels; Purkinje Fibers; Quaternary Ammonium Compounds; Quinidine; Sodium Channels; Sotalol; Sulfonamides	1996
Inhibition of cardiac potassium currents by the vesnarinone analog OPC-18790: comparison with quinidine and dofetilide. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:3 Topics: Animals; Cardiotonic Agents; Female; L Cells; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenethylamines; Potassium Channel Blockers; Quinidine; Quinolones; Recombinant Proteins; Sulfonamides	1997
Rapid inactivation determines the rectification and [K+]o dependence of the rapid component of the delayed rectifier K+ current in cardiac cells. Circulation research, 1997, Volume: 80, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Electric Conductivity; Electrophysiology; Female; Heart; Hybridization, Genetic; Magnesium; Mice; Mice, Inbred Strains; Myocardium; Osmolar Concentration; Phenethylamines; Potassium; Quinidine; Sulfonamides; Time Factors; Tumor Cells, Cultured	1997
Molecular determinant of high-affinity dofetilide binding to HERG1 expressed in Xenopus oocytes: involvement of S6 sites. Molecular pharmacology, 2000, Volume: 57, Issue:2 Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Binding Sites; Cation Transport Proteins; Ether-A-Go-Go Potassium Channels; Models, Biological; Mutation; Oocytes; Phenethylamines; Phenylalanine; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Recombinant Proteins; Sulfonamides; Tetraethylammonium; Xenopus laevis	2000
Species plays an important role in drug-induced prolongation of action potential duration and early afterdepolarizations in isolated Purkinje fibers. Journal of cardiovascular electrophysiology, 2001, Volume: 12, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Electrophysiology; In Vitro Techniques; Mammals; Phenethylamines; Purkinje Fibers; Quinidine; Reaction Time; Species Specificity; Sulfonamides	2001
A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link? The Journal of physiology, 2002, Apr-01, Volume: 540, Issue:Pt 1 Topics: Adrenergic alpha-Antagonists; Animals; Cation Transport Proteins; CHO Cells; Cricetinae; Ether-A-Go-Go Potassium Channels; Female; Gene Expression; Guinea Pigs; Male; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Oocytes; Patch-Clamp Techniques; Phenethylamines; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Xenopus laevis	2002
Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels. Basic & clinical pharmacology & toxicology, 2004, Volume: 94, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Delayed Rectifier Potassium Channels; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Hydantoins; Hydrogen-Ion Concentration; Imidazoles; Imidazolidines; Myocardial Ischemia; Oocytes; Patch-Clamp Techniques; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Transfection; Xenopus	2004
Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels. Acta pharmacologica Sinica, 2004, Volume: 25, Issue:5 Topics: Animals; Anti-Allergic Agents; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Ganglionic Stimulants; Ion Channel Gating; Mutation; Nicotine; Oocytes; Patch-Clamp Techniques; Phenethylamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Terfenadine; Xenopus laevis	2004
Comparison of kinetic properties of quinidine and dofetilide block of HERG channels. European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3 Topics: Animals; Dose-Response Relationship, Drug; Electrophysiology; Gene Expression; Humans; Japan; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Phenethylamines; Potassium Channels, Voltage-Gated; Pyrazines; Quinidine; Quinolines; Sulfonamides; Time Factors; Xenopus laevis	2004
The influence of extracellular acidosis on the effect of IKr blockers. Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10, Issue:1 Topics: Acidosis; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Humans; Hydantoins; Imidazolidines; Myocardial Infarction; Oocytes; Phenethylamines; Piperazines; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Trans-Activators; Xenopus laevis	2005
Use of a failing rabbit heart as a model to predict torsadogenicity. Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 93, Issue:1 Topics: Amiodarone; Animals; Cardiac Output, Low; Cisapride; Dose-Response Relationship, Drug; Electrocardiography; Models, Animal; Phenethylamines; Quaternary Ammonium Compounds; Quinidine; Rabbits; Sulfonamides; Torsades de Pointes; Verapamil	2006
Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels. Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:11 Topics: Cell Line; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Kidney; Mesoridazine; Phenethylamines; Potassium; Potassium Channel Blockers; Quinidine; Sulfonamides; Terfenadine	2006
Assessment of QT-prolonging drugs in the isolated normal and failing rabbit hearts. The Journal of toxicological sciences, 2012, Volume: 37, Issue:3 Topics: Animals; Arrhythmias, Cardiac; Cisapride; Electrocardiography; Feasibility Studies; Glucose; Heart; Heart Failure; In Vitro Techniques; Male; Models, Animal; Phenethylamines; Quinidine; Rabbits; Sulfonamides; Torsades de Pointes; Tromethamine	2012
Looking for virtuous promiscuity: electrocardiographic evidence of multichannel drug block. Clinical pharmacology and therapeutics, 2014, Volume: 96, Issue:5 Topics: Acetanilides; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Phenethylamines; Piperazines; Potassium Channel Blockers; Quinidine; Ranolazine; Sulfonamides; Verapamil	2014
Characteristics of electromechanical window in anesthetized rabbit models of short QT and long QT syndromes. The Journal of toxicological sciences, 2017, Volume: 42, Issue:5 Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzopyrans; Biomarkers; Biomarkers, Pharmacological; Cromakalim; Disease Models, Animal; Electrocardiography; Isoflurane; Long QT Syndrome; Phenethylamines; Pinacidil; Quinidine; Rabbits; Risk; Sulfonamides; Systole; Torsades de Pointes; Ventricular Pressure	2017
Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals. PloS one, 2018, Volume: 13, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; In Vitro Techniques; Perfusion; Phenethylamines; Procainamide; Quinidine; Sulfonamides	2018
Effects of antiarrhythmics on the electrical restitution in perfused guinea-pig heart are critically determined by the applied cardiac pacing protocol. Experimental physiology, 2019, Volume: 104, Issue:4 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Electrocardiography; Female; Guinea Pigs; Heart; Heart Conduction System; Heart Ventricles; Phenethylamines; Quinidine; Refractory Period, Electrophysiological; Sulfonamides; Ventricular Fibrillation	2019
Changes in global electrical heterogeneity associated with dofetilide, quinidine, ranolazine, and verapamil. Heart rhythm, 2020, Volume: 17, Issue:3 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Heart Ventricles; Humans; Male; Phenethylamines; Potassium Channel Blockers; Quinidine; Ranolazine; Risk Assessment; Sodium Channel Blockers; Sulfonamides; Treatment Outcome	2020
Antiarrhythmic drug effects on premature beats are partly determined by prior cardiac activation frequency in perfused guinea-pig heart. Experimental physiology, 2020, Volume: 105, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Phenethylamines; Procainamide; Quinidine; Sulfonamides	2020
Assessment of Drug Proarrhythmic Potential in Electrically Paced Human Induced Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes Using Multielectrode Array. SLAS discovery : advancing life sciences R & D, 2021, Volume: 26, Issue:3 Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cations, Divalent; Cell Differentiation; Humans; Induced Pluripotent Stem Cells; Ion Transport; Microelectrodes; Models, Biological; Myocardial Contraction; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Phenethylamines; Primary Cell Culture; Quinidine; Sotalol; Sulfonamides; Tetrodotoxin; Verapamil	2021