quinidine has been researched along with tetraethylammonium in 90 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (10.00) | 18.7374 |
1990's | 49 (54.44) | 18.2507 |
2000's | 25 (27.78) | 29.6817 |
2010's | 7 (7.78) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Arndt, P; Busch, AE; Gorboulev, V; Koepsell, H; Lang, F; Quester, S; Ulzheimer, JC; Waldegger, S | 1 |
Dresser, MJ; Giacomini, KM; Gray, AT; Terashita, S; Yost, SC; Zhang, L | 1 |
Inui, KI; Ito, T; Tanaka, K; Yano, I | 1 |
Giacomini, KM; Schaner, ME; Zhang, L | 1 |
Inui, KI; Masuda, S; Okuda, M; Saito, H; Urakami, Y | 1 |
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
Hashimoto, N; Nezu Ji, J; Nikaido, H; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A | 1 |
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
Akhoundova, A; Arndt, P; Bamberg, E; Budiman, T; Gorboulev, V; Koepsell, H; Koppatz, S; Nagel, G; Popp, C; Ulzheimer-Teuber, I; Volk, C | 1 |
Arieff, Z; Bardien-Kruger, S; Brink, P; Chandy, KG; Corfield, V; Wulff, H | 1 |
Akazawa, M; Inui, K; Okuda, M; Saito, H; Urakami, Y | 1 |
Bednarczyk, D; Ekins, S; Wikel, JH; Wright, SH | 1 |
Galanakis, D; Ganellin, CR | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Bedoya, M; Decher, N; González, W; Kiper, AK; Ramírez, D; Rinné, S | 1 |
Hara, N; Ichinose, M; Maeno, T; Sawada, M | 1 |
Knoth, KM; Roberds, SL; Snyders, J; Tamkun, MM | 1 |
Cukierman, S; Jia, H; Walker, AM; Wang, YF | 1 |
Jesuś García, J; Pasantes-Morales, H; Sánchez Olea, R | 1 |
Gorczyca, MG; Wu, CF | 1 |
Laurent, G | 1 |
Bauer, CK; Meyerhof, W; Schwarz, JR | 1 |
Hisada, T; Kurachi, Y; Sugimoto, T | 1 |
Deitmer, JW; Eckert, R | 1 |
Couraud, F; Marqueze, B; Seagar, MJ | 1 |
Beech, DJ; Bolton, TB | 1 |
Aldrich, RW; Hoshi, T | 1 |
Bidet, M; Le Maout, S; Merot, J; Poujeol, P; Tauc, M | 1 |
Greger, R; Kunzelmann, K; Pavenstädt, H | 1 |
Marcus, DC; Wangemann, P | 1 |
DeLeon, C; McKinney, TD; Speeg, KV | 1 |
Fukushima, Y; Hagiwara, S; Henkart, M | 1 |
Brochiero, E; Ehrenfeld, J; Raschi, C | 1 |
Boucher, A; Eng, JW; Hanrahan, JW; Harris, RA; Tabcharani, JA | 1 |
Díaz, M; Sepúlveda, FV | 1 |
Cook, DI; Hayashi, T; Hirono, C; Young, JA | 1 |
Diaz, J; Muallem, S; Xu, X; Zhao, H | 1 |
Clark, RB; Duff, HJ; Giles, WR; Salinas-Stefanon, E; Sanchez-Chapula, J | 1 |
Cook, DI; Ishikawa, T | 1 |
Peterson, VA; Strobl, JS; Wonderlin, WF; Woodfork, KA | 1 |
Agarwal, AK; Rao, SS | 2 |
Arvind, A; Sambasiva, R | 1 |
Bendayan, R; Lo, B; Silverman, M | 1 |
Farrugia, G; Rae, JL; Sarr, MG; Szurszewski, JH | 1 |
Farrugia, G; Rae, JL; Szurszewski, JH | 1 |
Ahn, SC; Kim, KW; Kim, SJ; So, I | 1 |
Berweck, S; Böhmig, M; Garbe, C; Leo, CP; Lepple-Wienhues, A; Meyling, B; Wiederholt, M | 1 |
Inui, K; Okuda, M; Saito, H; Takano, M; Urakami, Y | 1 |
Lomax, RB; Sandle, GI; Warhurst, G | 1 |
Hu, Q; Shi, YL | 1 |
Horimoto, N; Nabekura, J; Ogawa, T | 1 |
Akaike, N; Ebihara, S; Hida, W; Kikuchi, Y; Nishiyama, A; Okamoto, H; Oshiro, T; Sasaki, T; Shimura, S; Shirato, K; Takasawa, S | 1 |
Butterfield, I; Jones, MN; Sandle, GI; Warhurst, G | 1 |
Miranda, D; Morán, J; Pasantes-Morales, H; Sánchez Olea, R | 1 |
Attali, B; Cherepanov, V; Kolot, A; Sobko, A; Soliven, B; Wang, N | 1 |
Akaike, N; Kakehata, S; Saito, H; Saito, T; Yamada, T; Yamamoto, T | 1 |
Chavez, RA; Forsayeth, JR; Gray, AT; Harada, M; Kindler, CH; Leonoudakis, D; Taylor, DM; Winegar, BD; Yost, CS | 1 |
Buckingham, SD; Cayre, M; Sattelle, DB; Strambi, A; Strambi, C | 1 |
Abitbol, I; Attali, B; Peretz, A; Sobko, A; Wu, CF | 1 |
Wright, SH; Wunz, TM | 1 |
Clauss, W; Heinke, B | 1 |
Murakami, M; Nishi, K; Tokutomi, N; Tokutomi, Y; Tomita, K | 1 |
Dufy, B; Dufy-Barbe, L; Prevarskaya, N; Skryma, R; Van Coppenolle, F | 1 |
Furuichi, K; Kohda, M; Miyake, A; Mochizuki, S; Yokoi, H | 1 |
Klimatcheva, E; Wonderlin, WF | 1 |
Duan, Y; Duff, HJ; Lees-Miller, JP; Teng, GQ | 1 |
Kemp, PJ; O'Kelly, I; Peers, C | 1 |
Fukada, A; Inui, KI; Ohnishi, S; Saito, H | 1 |
Fu, Y; Hao, XM; Jin, H; Liu, TF | 1 |
Fukuda, K; Kato, T; Kodama, H; Miyoshi, S; Ogawa, S; Tahara, S | 1 |
Aoki, T; Hino, N; Ochi, R; Wang, W; Yamasaki, H | 1 |
Appel, SB; Brodie, MS; Liu, Z; McElvain, MA | 1 |
O'Donnell, MJ; Rheault, MR | 1 |
Arberry, LA; Choisy, SC; Hancox, JC; James, AF; Reynolds, AM; Shattock, MJ | 1 |
Fukami, T; Furuishi, T; Moriki, Y; Suzuki, T; Tomono, K; Watanabe, J | 1 |
Gruhn, M; Guckenheimer, J; Harris-Warrick, RM; Land, B | 1 |
Bijelic, G; Kim, NR; O'Donnell, MJ | 1 |
O'Donnell, MJ; Plaumann, JS; Rheault, MR | 1 |
Bourdet, DL; Thakker, DR | 1 |
Inui, K; Katsura, T; Masuda, S; Sato, T; Tanihara, Y; Yonezawa, A | 1 |
Hashimoto, Y; Kagawa, Y; Taguchi, M; Tahara, K; Takaai, M | 1 |
Inazu, M; Matsumiya, T; Tajima, H; Takeda, H; Uchida, Y; Yamada, T | 1 |
Hashimoto, Y; Horie, A; Ishida, K; Ito, T; Masago, M; Sakata, J; Taguchi, M; Takaai, M | 1 |
Azad, R; Bhatnagar, A; Biswas, NR; Ghose, S; Mittal, G; Nirmal, J; Singh, SB; Thavaraj, V; Velpandian, T | 1 |
Azad, RV; Biswas, NR; Nirmal, J; Singh, SB; Thavaraj, V; Velpandian, T | 1 |
2 review(s) available for quinidine and tetraethylammonium
Article | Year |
---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
TASK Channels Pharmacology: New Challenges in Drug Design.
Topics: Animals; Drug Design; Drug Discovery; Humans; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Tandem Pore Domain | 2019 |
88 other study(ies) available for quinidine and tetraethylammonium
Article | Year |
---|---|
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
Topics: Animals; Base Sequence; Biological Transport; Carrier Proteins; Cations; Choline; Electric Conductivity; Kidney; Lidocaine; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Niacinamide; Organic Cation Transporter 1; Pyridinium Compounds; Rats; Recombinant Proteins; Substrate Specificity | 1996 |
Cloning and functional expression of a human liver organic cation transporter.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Liver; Membrane Proteins; Molecular Sequence Data; Oocytes; Organic Cation Transporter 1; Polymerase Chain Reaction; Rats; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Tissue Distribution; Xenopus laevis | 1997 |
Transport of quinolone antibacterial drugs by human P-glycoprotein expressed in a kidney epithelial cell line, LLC-PK1.
Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Epithelial Cells; Epithelium; Fluoroquinolones; Humans; Kidney; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Quinolones; Swine | 1997 |
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection | 1998 |
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
Topics: Animals; Base Sequence; Carrier Proteins; Cations; Cell Line; Cell Membrane; DNA Primers; Dogs; Kidney Tubules; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Tetraethylammonium | 1998 |
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis | 1999 |
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism | 1999 |
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tissue Distribution; Tritium | 2001 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
Topics: Animals; Anions; Carrier Proteins; Cations; Cell Line; Cell Membrane; Choline; Cloning, Molecular; Female; Guanidine; Histamine; Humans; In Vitro Techniques; Kidney; Kinetics; Membrane Potentials; Membrane Proteins; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Transfection; Xenopus laevis | 2001 |
Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI).
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA; Heart Block; Heart Diseases; Humans; Mice; Molecular Sequence Data; Potassium Channels; Potassium Channels, Voltage-Gated; Shaker Superfamily of Potassium Channels; Trinucleotide Repeats | 2002 |
cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.
Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Cations; Cell Line; Cloning, Molecular; DNA, Complementary; Genetic Variation; Humans; Kidney; Molecular Sequence Data; Organic Cation Transport Proteins; Organic Cation Transporter 2; Tetraethylammonium; Tissue Distribution; Transfection | 2002 |
Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.
Topics: Computational Biology; HeLa Cells; Humans; Models, Molecular; Organic Cation Transporter 1; Pyridinium Compounds; Quinolinium Compounds; Structure-Activity Relationship; Transfection | 2003 |
Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry.
Topics: Animals; Apamin; Guinea Pigs; Hepatocytes; Kinetics; Molecular Conformation; Potassium Channels, Calcium-Activated | 2004 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Induction of two K+ currents by complement component C5a in mouse macrophages.
Topics: Animals; Calcium; Charybdotoxin; Complement C5a; Dinoprostone; Egtazic Acid; Electrophysiology; Macrophages; Mice; Mice, Inbred C3H; Potassium; Quinidine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Heart; Humans; Kinetics; L Cells; Membrane Potentials; Mice; Molecular Sequence Data; Myocardium; Potassium; Potassium Channels; Quinidine; Receptors, Drug; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Transfection | 1992 |
K-current mediation of prolactin-induced proliferation of malignant (Nb2) lymphocytes.
Topics: 4-Aminopyridine; Animals; Barium; Cell Division; Lymphocytes; Lymphoma; Potassium Channels; Prolactin; Quinidine; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1992 |
Taurine release associated to volume regulation in rabbit lymphocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acids; Animals; Calcimycin; Colchicine; Cytochalasin B; Furosemide; Hypotonic Solutions; Ion Channels; Lymphocytes; Quinidine; Rabbits; Taurine; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Single-channel K+ currents in Drosophila muscle and their pharmacological block.
Topics: Animals; Barium; Drosophila; Electric Conductivity; Muscles; Potassium Channels; Quinidine; Stress, Mechanical; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Evidence for voltage-activated outward currents in the neuropilar membrane of locust nonspiking local interneurons.
Topics: 4-Aminopyridine; Animals; Cell Membrane; Cobalt; Electric Conductivity; Evoked Potentials; Grasshoppers; In Vitro Techniques; Interneurons; Kinetics; Membrane Potentials; Potassium Channels; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1991 |
An inward-rectifying K+ current in clonal rat pituitary cells and its modulation by thyrotrophin-releasing hormone.
Topics: 4-Aminopyridine; Animals; Barium; Cesium; Membrane Potentials; Pituitary Gland, Anterior; Potassium Channels; Quinidine; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Thyrotropin-Releasing Hormone; Time Factors | 1990 |
Properties of membrane currents in isolated smooth muscle cells from guinea-pig trachea.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium; Calcium Channels; Cell Membrane Permeability; Cells, Cultured; Electric Conductivity; Guinea Pigs; Kinetics; Membrane Potentials; Muscle, Smooth; Potassium; Potassium Channels; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Trachea | 1990 |
Two components of Ca-dependent potassium current in identified neurons of Aplysia californica.
Topics: Animals; Apamin; Aplysia; Calcium; Dose-Response Relationship, Drug; Drug Resistance; Electric Conductivity; Ion Channels; Neurons; Potassium; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1985 |
Solubilization of the apamin receptor associated with a calcium-activated potassium channel from rat brain.
Topics: Animals; Apamin; Binding, Competitive; Brain; Calcium; Gallamine Triethiodide; Ion Channels; Kinetics; Potassium; Potassium Channels; Quinidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Synaptosomes; Tetraethylammonium; Tetraethylammonium Compounds; Tubocurarine | 1987 |
The effects of tetraethylammonium ions, 4-aminopyridine or quinidine on K+-currents in single smooth muscle cells of the rabbit portal vein.
Topics: 4-Aminopyridine; Aminopyridines; Animals; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscle, Smooth, Vascular; Potassium; Quinidine; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Voltage-dependent K+ currents and underlying single K+ channels in pheochromocytoma cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Charybdotoxin; Ion Channels; Membrane Potentials; Pheochromocytoma; Potassium; Quinidine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1988 |
Two types of K+ channels in the apical membrane of rabbit proximal tubule in primary culture.
Topics: Alkaline Phosphatase; Animals; Barium; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Electric Conductivity; gamma-Glutamyltransferase; Hexokinase; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Kinetics; Leucyl Aminopeptidase; Membrane Potentials; Parathyroid Hormone; Potassium Channels; Quinidine; Rabbits; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
Characterization of potassium channels in respiratory cells. II. Inhibitors and regulation.
Topics: Adenosine Triphosphate; Barium; Calcium; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Cystic Fibrosis; Epithelial Cells; Epithelium; Guanosine Triphosphate; Humans; Hydrogen-Ion Concentration; Lidocaine; Membrane Potentials; Nasal Polyps; Potassium; Potassium Channels; Quinidine; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
Membrane potential measurements of transitional cells from the crista ampullaris of the gerbil. Effects of barium, quinidine, quinine, tetraethylammonium, cesium, ammonium, thallium and ouabain.
Topics: Animals; Cations; Chlorides; Ear, Inner; Electrophysiology; Gerbillinae; In Vitro Techniques; Membrane Potentials; Ouabain; Quinidine; Quinine; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
Organic cation uptake by a cultured renal epithelium.
Topics: Animals; Azides; Biological Transport; Cell Line; Cimetidine; Epithelial Cells; Epithelium; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Kinetics; Quinidine; Sodium Azide; Temperature; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Potassium current in clonal cytotoxic T lymphocytes from the mouse.
Topics: Action Potentials; Animals; Cells, Cultured; Clone Cells; Electric Conductivity; Magnesium; Membrane Potentials; Mice; Potassium; Quinidine; T-Lymphocytes, Cytotoxic; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1984 |
Basolateral potassium membrane permeability of A6 cells and cell volume regulation.
Topics: Animals; Calcium; Cell Line; Cell Membrane Permeability; Cell Size; Glyburide; Ion Channels; Ion Transport; Kidney; Models, Biological; Osmotic Pressure; Potassium; Quinidine; Rubidium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Xenopus laevis | 1994 |
Basolateral K channel activated by carbachol in the epithelial cell line T84.
Topics: 4-Aminopyridine; Calcimycin; Carbachol; Cell Membrane; Charybdotoxin; Colonic Neoplasms; Cyclic AMP; Epithelium; Fluorescence; Humans; Ionomycin; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Quinidine; Scorpion Venoms; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tumor Cells, Cultured | 1994 |
Characterisation of Ca(2+)-dependent inwardly rectifying K+ currents in HeLa cells.
Topics: Adenosine Triphosphate; Barium; Bradykinin; Calcium; Cations, Monovalent; Cell Membrane Permeability; Charybdotoxin; Edetic Acid; Electric Conductivity; HeLa Cells; Histamine; Humans; Magnesium; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Quinidine; Quinine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
The ACh-induced whole-cell currents in sheep parotid secretory cells. Do BK channels really carry the ACh-evoked whole-cell K+ current?
Topics: 4-Aminopyridine; Acetylcholine; Animals; Barium; Cell Membrane; Chlorides; Parotid Gland; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Sensitivity and Specificity; Sheep; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1995 |
Regulation of [Na+]i in resting and stimulated submandibular salivary ducts.
Topics: Amiloride; Animals; Barium Compounds; Carbachol; Ion Transport; Male; Ouabain; Quinidine; Quinine; Rats; Sodium; Submandibular Gland; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Quinidine-induced open channel block of K+ current in rat ventricle.
Topics: Action Potentials; Animals; Electrophysiology; Heart Ventricles; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Effects of K+ channel blockers on inwardly and outwardly rectifying whole-cell K+ currents in sheep parotid secretory cells.
Topics: Animals; Barium; Cesium; Charybdotoxin; In Vitro Techniques; Lidocaine; Membrane Potentials; Parotid Gland; Potassium; Potassium Channels; Quinidine; Quinine; Scorpion Venoms; Sheep; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1993 |
Inhibition of ATP-sensitive potassium channels causes reversible cell-cycle arrest of human breast cancer cells in tissue culture.
Topics: 4-Aminopyridine; Breast Neoplasms; Cell Cycle; Cell Division; Glyburide; Humans; Potassium Channel Blockers; Potassium Channels; Pyrrolidines; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1995 |
Effect of quinidine on kidney biochemistry and function in male Sprague-Dawley rats.
Topics: Analysis of Variance; Animals; Biological Transport; In Vitro Techniques; Injections, Intraperitoneal; Kidney Cortex; Kidney Function Tests; L-Lactate Dehydrogenase; Male; Mitochondria; Oxygen Consumption; p-Aminohippuric Acid; Quinidine; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Effects of quinidine on renal biochemistry and function in young and old rats.
Topics: Aging; Animals; Blood Urea Nitrogen; Creatinine; In Vitro Techniques; Kidney Cortex; Male; Mitochondria; Oxygen Consumption; p-Aminohippuric Acid; Quinidine; Rats; Rats, Inbred F344; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Characterization of cimetidine transport in LLCPK1 cells.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Azides; Biological Transport; Carrier Proteins; Cell Line; Cimetidine; Guanidine; Guanidines; Kidney; Macrolides; Microscopy, Fluorescence; Models, Biological; Niacinamide; Proton-Translocating ATPases; Quinidine; Quinine; Sodium Azide; Sodium-Hydrogen Exchangers; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Potassium current in circular smooth muscle of human jejunum activated by fenamates.
Topics: 4-Aminopyridine; Cadmium; Flufenamic Acid; Humans; In Vitro Techniques; Ion Channel Gating; Jejunum; Kinetics; Mefenamic Acid; Membrane Potentials; Muscle, Smooth; Potassium Channels; Potassium Chloride; Probability; Quinidine; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
Characterization of an outward potassium current in canine jejunal circular smooth muscle and its activation by fenamates.
Topics: Animals; Calcium; Dogs; Electric Conductivity; Female; Flufenamic Acid; In Vitro Techniques; Jejunum; Male; Mefenamic Acid; Membrane Potentials; Muscle, Smooth; Potassium; Potassium Channels; Quinidine; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
In vitro and in vivo effects of quinidine on the kidneys in Fischer-344 rats.
Topics: Aminohippuric Acids; Animals; Biological Transport; In Vitro Techniques; Kidney Cortex; Mitochondria; Oxygen Consumption; Quinidine; Rats; Rats, Inbred F344; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
Quinidine blockade of the carbachol-activated nonselective cationic current in guinea-pig gastric myocytes.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Anti-Arrhythmia Agents; Calcium Channels; Carbachol; Cations; Dose-Response Relationship, Drug; Electrophysiology; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ion Transport; Male; Microelectrodes; Muscle, Smooth; Potassium Channels; Quinidine; Receptors, Muscarinic; Stomach; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
K+ channels and the intracellular calcium signal in human melanoma cell proliferation.
Topics: Animals; Barium; Blood Physiological Phenomena; Calcium; Cattle; Cell Cycle; Cell Division; Charybdotoxin; Culture Media; Fibroblast Growth Factor 2; Humans; Melanoma; Membrane Potentials; Neoplasm Proteins; Patch-Clamp Techniques; Potassium; Potassium Channels; Quinidine; Signal Transduction; Skin Neoplasms; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1996 |
cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Blotting, Northern; Carrier Proteins; Cimetidine; Cloning, Molecular; DNA Primers; DNA, Complementary; Female; In Vitro Techniques; Kidney; Membrane Proteins; Molecular Sequence Data; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Polymerase Chain Reaction; Procainamide; Quinidine; Rats; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Tetraethylammonium; Tetraethylammonium Compounds; Xenopus laevis | 1996 |
Characteristics of two basolateral potassium channel populations in human colonic crypts.
Topics: Case-Control Studies; Colon; Humans; Intestinal Mucosa; ortho-Aminobenzoates; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Characterization of an inward-rectifying potassium current in NG108-15 neuroblastoma x glioma cells.
Topics: 4-Aminopyridine; Barium; Bucladesine; Cadmium; Calcium; Cell Differentiation; Cesium; Cobalt; Cyclic AMP; Glioma; Neuroblastoma; Patch-Clamp Techniques; Potassium Channels; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1997 |
Arachidonic acid activation of potassium channels in rat visual cortex neurons.
Topics: 4-Aminopyridine; Animals; Apamin; Arachidonic Acid; Barium; Charybdotoxin; Docosahexaenoic Acids; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Glyburide; In Vitro Techniques; Indomethacin; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds; Visual Cortex | 1997 |
Role of cyclic ADP-ribose in ATP-activated potassium currents in alveolar macrophages.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Apamin; Calcium; Charybdotoxin; Cyclic ADP-Ribose; Dose-Response Relationship, Drug; Macrophages, Alveolar; Nystatin; Potassium Channel Blockers; Potassium Channels; Quinidine; Rats; Rats, Wistar; Second Messenger Systems; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Characterization of apical potassium channels induced in rat distal colon during potassium adaptation.
Topics: Adaptation, Physiological; Animals; Barium; Calcium; Colon; Electric Conductivity; Ion Transport; Male; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium, Dietary; Quinidine; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. I. Regulatory volume decrease.
Topics: 3T3 Cells; 4-Aminopyridine; Animals; Anions; ATP Binding Cassette Transporter, Subfamily B, Member 1; Barium; Cell Membrane Permeability; Chloride Channels; Chlorides; Colchicine; Colforsin; Dipyridamole; Gramicidin; Kinetics; Mice; Niflumic Acid; Nitrobenzoates; Potassium Channel Blockers; Potassium Channels; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Water-Electrolyte Balance | 1997 |
Characterization of delayed rectifier Kv channels in oligodendrocytes and progenitor cells.
Topics: 4-Aminopyridine; Animals; Cell Differentiation; Cell Line; Delayed Rectifier Potassium Channels; Humans; In Situ Hybridization; Ion Transport; Kidney; Kv1.2 Potassium Channel; Kv1.4 Potassium Channel; Kv1.5 Potassium Channel; Macromolecular Substances; Multigene Family; Nerve Tissue Proteins; Oligodendroglia; Oligonucleotides, Antisense; Patch-Clamp Techniques; Polymerase Chain Reaction; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quaternary Ammonium Compounds; Quinidine; Quinine; Rats; Recombinant Fusion Proteins; RNA, Messenger; Stem Cells; Tetraethylammonium; Transfection | 1997 |
Effects of potassium channel blockers on the acetylcholine-induced currents in dissociated outer hair cells of guinea pig cochlea.
Topics: 4-Aminopyridine; Acetylcholine; Analgesics, Non-Narcotic; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hair Cells, Auditory, Outer; Male; Nicotinic Antagonists; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Scorpion Venoms; Tetraethylammonium; Tubocurarine | 1997 |
An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum.
Topics: Acids; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Barium; Blotting, Northern; Bupivacaine; Central Nervous System Depressants; Cerebellum; Cloning, Molecular; Ethanol; Ion Channel Gating; Lidocaine; Magnesium; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Peptides; Phenytoin; Phosphorylation; Potassium Channels; Quinidine; Rats; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tetraethylammonium; Xenopus; Zinc | 1998 |
Adult insect mushroom body neurons in primary culture: cell morphology and characterization of potassium channels.
Topics: Animals; Axonal Transport; Brain; Cadmium; Cell Survival; Cells, Cultured; Culture Techniques; DNA Replication; Ganglia, Invertebrate; Gryllidae; Horseradish Peroxidase; Membrane Potentials; Neurons; Potassium Channels; Quinidine; Tetraethylammonium | 1998 |
A Ca2+/calmodulin-dependent protein kinase modulates Drosophila photoreceptor K+ currents: a role in shaping the photoreceptor potential.
Topics: Adaptation, Ocular; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Drosophila; Drosophila Proteins; Enzyme Inhibitors; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Photoreceptor Cells, Invertebrate; Potassium Channels; Quinidine; Reaction Time; Shaker Superfamily of Potassium Channels; Sulfonamides; Tetraethylammonium; Vasodilator Agents; Vision, Ocular | 1998 |
Influence of substrate structure on substrate binding to the renal organic cation/H+ exchanger.
Topics: Acridines; Animals; Antiporters; Carbon Radioisotopes; Cations; Ephedrine; Ion Transport; Kidney Cortex; Microvilli; Molecular Structure; Nicotine; Pyridinium Compounds; Quinidine; Quinine; Quinolinium Compounds; Rabbits; Stereoisomerism; Structure-Activity Relationship; Tetraethylammonium | 1999 |
Potassium conductances in isolated single cells from Xenopus laevis colonic epithelium.
Topics: Animals; Barium; Cesium; Colon; Epithelial Cells; Female; Hydrogen-Ion Concentration; Ion Transport; Lidocaine; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Tetraethylammonium; Verapamil; Xenopus laevis | 1999 |
Alkalinization-induced K+ current of the mouse megakaryocyte.
Topics: 4-Aminopyridine; Animals; Calcium; Electric Stimulation; Hydrogen-Ion Concentration; Megakaryocytes; Membrane Potentials; Mice; Mice, Inbred BALB C; Potassium Channel Blockers; Potassium Channels; Quinidine; Streptomycin; Tetraethylammonium | 1999 |
Characterization of Ca(2+)-inhibited potassium channels in the LNCaP human prostate cancer cell line.
Topics: Adenocarcinoma; Calcium; Charybdotoxin; Elapid Venoms; Humans; Ion Channel Gating; Ion Transport; Lymphatic Metastasis; Male; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Prostatic Neoplasms; Quinidine; Tetraethylammonium; Tumor Cells, Cultured | 1999 |
New ether-à-go-go K(+) channel family members localized in human telencephalon.
Topics: Amino Acid Sequence; Cell Line; Chromosome Mapping; Chromosomes, Human, Pair 12; Cloning, Molecular; Ether-A-Go-Go Potassium Channels; Humans; In Situ Hybridization; Ion Channel Gating; Molecular Sequence Data; Nerve Tissue Proteins; Patch-Clamp Techniques; Phylogeny; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Receptor Protein-Tyrosine Kinases; Receptor, EphB4; Receptors, Eph Family; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Telencephalon; Tetraethylammonium; Transfection | 1999 |
An ATP-sensitive K(+) current that regulates progression through early G1 phase of the cell cycle in MCF-7 human breast cancer cells.
Topics: Adenosine Triphosphate; Breast Neoplasms; Calcium; Female; G1 Phase; Gene Expression; Genes, ras; Glyburide; Humans; Intracellular Fluid; Ion Transport; Membrane Potentials; Potassium; Potassium Channel Blockers; Pyrrolidines; Quinidine; Tetraethylammonium; Tumor Cells, Cultured | 1999 |
Molecular determinant of high-affinity dofetilide binding to HERG1 expressed in Xenopus oocytes: involvement of S6 sites.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Binding Sites; Cation Transport Proteins; Ether-A-Go-Go Potassium Channels; Models, Biological; Mutation; Oocytes; Phenethylamines; Phenylalanine; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Recombinant Proteins; Sulfonamides; Tetraethylammonium; Xenopus laevis | 2000 |
O2-sensing by model airway chemoreceptors. Hypoxic inhibition of K+ channels in H146 cells.
Topics: 4-Aminopyridine; Cadmium; Calcium Channels; Cell Hypoxia; Cell Line; Chemoreceptor Cells; Humans; Lung; Membrane Potentials; Oxygen; Potassium Channel Blockers; Potassium Channels; Pulmonary Circulation; Quinidine; Sodium Channels; Tetraethylammonium | 2000 |
Independent organic cation transport activity of Na(+)-L-carnitine cotransport system in LLC-PK(1) cells.
Topics: Animals; Carnitine; Carrier Proteins; Cations; Cell Line; Cell Polarity; Cephaloridine; Cephalosporins; Cimetidine; Enzyme Inhibitors; Epithelial Cells; Hydrogen-Ion Concentration; Ion Transport; Kidney Tubules, Proximal; Kinetics; Quinidine; Sodium; Swine; Tetraethylammonium | 2001 |
Calcium-activated potassium current in single Novikoff cell.
Topics: Animals; Apamin; Cell Line; Egtazic Acid; Electric Stimulation; Electrophysiology; Liver Neoplasms, Experimental; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Quinidine; Tetraethylammonium | 2001 |
Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channels, L-Type; Cells, Cultured; Cytochalasin D; Drug Evaluation, Preclinical; ErbB Receptors; Focal Adhesion Kinase 2; Mitogen-Activated Protein Kinases; Myocardium; Phosphorylation; Piperidines; Potassium Channel Blockers; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Quinidine; Rats; Rats, Wistar; Tetraethylammonium; Time Factors; Tyrphostins | 2001 |
KV2.1 K+ channels underlie major voltage-gated K+ outward current in H9c2 myoblasts.
Topics: Amino Acid Sequence; Cell Line; Delayed Rectifier Potassium Channels; Gene Expression Regulation; Heart Ventricles; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Muscle Cells; Myoblasts; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sequence Alignment; Shab Potassium Channels; Tetraethylammonium; Ventricular Function | 2002 |
Ethanol excitation of dopaminergic ventral tegmental area neurons is blocked by quinidine.
Topics: Adrenergic alpha-Antagonists; Animals; Barium; Central Nervous System Depressants; Cesium; Cyclic Nucleotide-Gated Cation Channels; Dopamine; Drug Interactions; Ethanol; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Ion Channels; Male; Neurons; Potassium Channels; Pyrimidines; Quinidine; Rats; Rats, Inbred F344; Receptors, Dopamine; Tetraethylammonium; Ventral Tegmental Area | 2003 |
Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological methods.
Topics: Animals; Biological Transport, Active; Cimetidine; Drosophila melanogaster; Electrophysiology; Ion Transport; Malpighian Tubules; Microelectrodes; Potassium; Quinidine; Tetraethylammonium; Tetraphenylborate; Verapamil; Vinblastine | 2004 |
Evidence for a novel K(+) channel modulated by alpha(1A)-adrenoceptors in cardiac myocytes.
Topics: Acidosis; Animals; Electrophysiology; GTP-Binding Proteins; Heart; Male; Myocytes, Cardiac; Nerve Tissue Proteins; Pertussis Toxin; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Sodium-Activated; Potassium Channels, Tandem Pore Domain; Quinidine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Signal Transduction; Tetraethylammonium; Time Factors | 2004 |
In vivo evidence for the efflux transport of pentazocine from the brain across the blood-brain barrier using the brain efflux index method.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Carnitine; Dose-Response Relationship, Drug; Drug Carriers; Drug Evaluation, Preclinical; Half-Life; Inulin; Male; Microinjections; Pentazocine; Quinidine; Rats; Rats, Wistar; Tetraethylammonium; Tritium; Verapamil | 2005 |
Dopamine modulation of two delayed rectifier potassium currents in a small neural network.
Topics: 4-Aminopyridine; Animals; Cadmium Chloride; Delayed Rectifier Potassium Channels; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Invertebrate; In Vitro Techniques; Membrane Potentials; Nerve Net; Neural Conduction; Neurons; Palinuridae; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Quinidine; Tetraethylammonium; Tetrodotoxin | 2005 |
Effects of dietary or injected organic cations on larval Drosophila melanogaster: mortality and elimination of tetraethylammonium from the hemolymph.
Topics: Animals; Biological Transport, Active; Cations; Cimetidine; Diet; Dose-Response Relationship, Drug; Drosophila melanogaster; Hemolymph; Larva; Lethal Dose 50; Malpighian Tubules; Quinidine; Survival Rate; Temperature; Tetraethylammonium | 2005 |
Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Chromatography, Thin Layer; Cimetidine; Female; In Vitro Techniques; Insecta; Male; Malpighian Tubules; Niacinamide; Nicotine; Quinidine; Rhodnius; Tetraethylammonium; Time Factors | 2006 |
Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein.
Topics: 2,4-Dinitrophenol; Absorption; Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cations; Cell Membrane Permeability; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Membrane Potentials; Organic Cation Transport Proteins; Quinidine; Ranitidine; Tetraethylammonium; Tetrahydroisoquinolines; Tritium; Uncoupling Agents | 2006 |
Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cell Line; Cimetidine; Dogs; Humans; Metformin; Octamer Transcription Factor-1; Organic Cation Transport Proteins; Organic Cation Transporter 2; Procainamide; Quinidine; Tetraethylammonium; Transfection | 2008 |
Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 Cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bisoprolol; Cells, Cultured; Cimetidine; LLC-PK1 Cells; Organic Cation Transport Proteins; Quinidine; Swine; Tetraethylammonium | 2008 |
Expression and functional characterization of choline transporter in human keratinocytes.
Topics: Acetylcholine; Anisoles; Antigens, CD; Biological Transport; Cell Membrane; Cells, Cultured; Choline; Clonidine; Desipramine; Diphenhydramine; Gene Expression Profiling; Humans; Keratinocytes; Membrane Potentials; Octamer Transcription Factor-3; Organic Cation Transport Proteins; p-Aminohippuric Acid; Quinidine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters; Tetraethylammonium; Time Factors; Tritium | 2009 |
Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells.
Topics: Animals; Anti-Arrhythmia Agents; Biological Transport, Active; Caco-2 Cells; Cation Transport Proteins; Cell Membrane; Drug Interactions; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Kidney; LLC-PK1 Cells; Procainamide; Quinidine; Swine; Temperature; Tetraethylammonium | 2010 |
Evaluation of the functional importance of organic cation transporters on the ocular disposition of its intravitreally injected substrate in rabbits.
Topics: Animals; Blood-Retinal Barrier; Chromatography, High Pressure Liquid; Female; Intravitreal Injections; Male; Organic Cation Transport Proteins; Potassium Channel Blockers; Quinidine; Rabbits; Tandem Mass Spectrometry; Technetium; Tetraethylammonium; Vitreous Body; Voltage-Gated Sodium Channel Blockers | 2012 |
Potential pharmacokinetic role of organic cation transporters in modulating the transcorneal penetration of its substrates administered topically.
Topics: Administration, Topical; Animals; Aqueous Humor; Atropine; Biological Transport; Chromatography, Liquid; Cornea; Mass Spectrometry; Metformin; Models, Animal; Organic Cation Transport Proteins; Quinidine; Rabbits; Tetraethylammonium; Tomography, Optical Coherence; Voltage-Gated Sodium Channel Blockers | 2013 |