quinidine has been researched along with quinine in 479 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 196 (40.92) | 18.7374 |
| 1990's | 120 (25.05) | 18.2507 |
| 2000's | 86 (17.95) | 29.6817 |
| 2010's | 71 (14.82) | 24.3611 |
| 2020's | 6 (1.25) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Guengerich, FP; Stöckigt, J; Strobl, GR; von Kruedener, S; Wolff, T | 1 |
| Akhoundova, A; Busch, AE; Gorboulev, V; Koepsell, H; Lang, F; Quester, S; Ulzheimer, JC; Waldegger, S | 1 |
| Arndt, P; Busch, AE; Gorboulev, V; Koepsell, H; Lang, F; Quester, S; Ulzheimer, JC; Waldegger, S | 1 |
| Dresser, MJ; Giacomini, KM; Gray, AT; Terashita, S; Yost, SC; Zhang, L | 1 |
| Giacomini, KM; Schaner, ME; Zhang, L | 1 |
| Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Akhoundova, A; Arndt, P; Bamberg, E; Budiman, T; Gorboulev, V; Koepsell, H; Koppatz, S; Nagel, G; Popp, C; Ulzheimer-Teuber, I; Volk, C | 1 |
| Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Abe, T; Itoh, T; Kato, Y; Kusuhara, H; Meier, PJ; Shitara, Y; Sugiyama, D; Sugiyama, Y | 1 |
| Choi, WS; Choi, YJ; Huh, SC; Huh, TL; Kim, DY; Kim, JE; Kim, MH; Kim, SM; Lee, BJ; Lee, SE; Park, BS; Park, E-; Rosenthal, PJ; Suh, KH | 1 |
| Pajeva, IK; Wiese, M | 1 |
| Commandeur, JN; Funae, Y; Hiroi, T; ter Laak, AM; Venhorst, J; Vermeulen, NP | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Galanakis, D; Ganellin, CR | 1 |
| Engel, K; Wang, J | 1 |
| Chen, X; Chong, CR; Liu, JO; Shi, L; Sullivan, DJ | 1 |
| Doh-ura, K; Fukuuchi, T; Kimata, A; Miyata, N; Nakagawa, H; Ohta, S; Ohyama, R; Suzuki, T | 1 |
| Acharya, BN; Kaushik, MP; Saraswat, D | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Dinio, T; Gorka, AP; McGinniss, A; Morgan, JB; Roepe, PD | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Bero, J; Frédérich, M; Leverrier, A; Palermo, J; Quetin-Leclercq, J | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bero, J; Cabrera, J; Frédérich, M; Leverrier, A; Palermo, JA; Quetin-Leclercq, J | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Wang, J | 1 |
| Bedoya, M; Decher, N; González, W; Kiper, AK; Ramírez, D; Rinné, S | 1 |
| Romankiewicz, JA | 1 |
| Horrobin, DF; Manku, MS | 2 |
| Hardie, RA; Pumford, S; Savin, JA; White, DA | 1 |
| Folen, VA | 1 |
| Scott, WA; Solomon, B | 1 |
| Brown, RD; Feldman, AM | 1 |
| Atwater, I; Dawson, CM; Ribalet, B; Rojas, E | 1 |
| Háznagy, A | 1 |
| Aster, RH; Johnson, MM; Kunicki, TJ | 1 |
| Levin, J; Zieve, PD | 1 |
| Aster, RH; Cimo, PL; Desai, RG; Pino, JL; Pisciotta, AV | 1 |
| Domula, M; Keller, J; Lenk, H; Weissbach, G | 1 |
| Kelly, RJ; Klevans, LR; Kovacs, JL | 1 |
| Diab, AM; Karawya, MS | 1 |
| Hanani, M; Shaw, C | 1 |
| Armando-Hardy, M; Ellory, JC; Ferreira, HG; Fleminger, S; Lew, VL | 1 |
| Chmel, K; Chmelová-Hlavatá, V | 1 |
| Abdine, H; Soliman, SA; Zakhari, NA | 1 |
| Berth, J; Bunnag, D; Chittamas, S; Druilhe, P; Harinasuta, T; Karbwang, J | 1 |
| Dixon, PA; Onyeji, CO; Ugwu, NC | 1 |
| Sitar, DS; Smyth, DD; Wong, LT | 2 |
| Hedman, A | 1 |
| Buchanan, WA | 1 |
| Hindsén, M; Isaksson, M; Ljunggren, B | 1 |
| Christie, DJ; Hammerschmidt, DE; Jacob, HS; Shankar, RA; Stroncek, DF; Vercellotti, GM | 1 |
| Edwards, G; Mansor, SM; Ward, SA | 1 |
| Breckenridge, AM; Edwards, G; Hoaksey, PE; Mansor, SM; Ward, SA | 2 |
| Duff, HJ; Rahmberg, M; Sheldon, RS | 2 |
| Aster, RH; Newman, PJ; Visentin, GP | 1 |
| Acmor-Apolinar, MM; Attanath, P; Chongsuphajaisiddhi, T; Pojjaroen-Anant, C; Sabchareon, A; Singhasivanon, V | 1 |
| Hollman, A | 1 |
| Hawes, EM; Korchinski, ED; McKay, G; Midha, KK; Muralidharan, G | 1 |
| Hawes, EM; McKay, G; Midha, KK; Muralidharan, G | 1 |
| Brookshier, LA; Clawson, DC; Hoyer, GL; Marcus, FI; Nolan, PE | 1 |
| Giacomini, KM; Hsyu, PH; Hui, AC; Ott, RJ; Wong, FM | 1 |
| Dutta, GP; Kazim, M; Puri, SK | 1 |
| Inaba, T; Kalow, W; Tyndale, RF | 1 |
| Majumdar, SK; Ray, L | 1 |
| Ching, MS; Czuba, MA; Ghabrial, H; Hardy, KJ; Mihaly, GW; Morgan, DJ; Smallwood, RA | 1 |
| Babalola, CP; Bolaji, OO; Dixon, PA | 1 |
| Björkman, A; Marbiah, N; Payne, D; Willcox, M | 1 |
| Ljunggren, B; Wirestrand, LE | 2 |
| Fallis, G | 1 |
| Monteagudo, FS; Pillai, G | 1 |
| Abdulrahman, S; Baldwin, MA; Harrison, ME; Phillipson, JD; Roberts, MF; Welham, KJ | 1 |
| Ayesh, R; Cholerton, S; Dawling, S; Hayler, A; Idle, JR; Oates, NS; Smith, RL; Widdop, B | 1 |
| Biollaz, J; Munafo, A; Reymond-Michel, G | 1 |
| Black, J; Wesche, DL | 1 |
| Kilimali, VA | 1 |
| Bedenne, L; Caillot, D; Chauffert, B; Corda, C; Martin, F; Pelletier, H; Solary, E | 1 |
| Aster, RH; Newman, PJ; Visentin, GP; Wolfmeyer, K | 1 |
| Davis, TM; Karbwang, J; Looareesuwan, S; Turner, RC; White, NJ | 1 |
| Hahn, EW; Osswald, H; Pommerenke, EW; Volm, M | 1 |
| Cooper, K; Dewey, J; Rae, JL; Rae, JS | 1 |
| Bazill, GW; Dexter, TM | 1 |
| Akintonwa, A; Orisakwe, OE | 1 |
| Prinz, A | 1 |
| Chongsuphajaisiddhi, T; Edstein, MD; Prasitthipayong, A; Sabchareon, A; Webster, HK | 1 |
| Angelin, B; Arvidsson, A; Dahlqvist, R; Hedman, A; Nilsson, B | 1 |
| Advenier, C; Leroyer, R; Pays, M; Varoquaux, O | 1 |
| Hasan, MM; Hassan, MA; Rawashdeh, NM | 1 |
| Tanabe, H | 1 |
| Abramcheck, FJ; Helman, SI; Van Driessche, W | 1 |
| Iwatsuki, N; Petersen, OH | 1 |
| Katayama, Y; Morita, K | 1 |
| Jamaludin, A; Mohamad, M; Mohamed, N; Navaratnam, V; Wernsdorfer, WH; Yeoh, PY | 1 |
| Kaneniwa, N; Wakamatsu, A; Watari, N | 1 |
| Dahlqvist, R; Dumont, E; Spina, E; Steiner, E | 2 |
| Barajas-López, C; Huizinga, JD | 1 |
| Bunnag, D; Karbwang, J; Molunto, P; Na Bangchang, K | 1 |
| Boobis, AR; Davies, DS; Kobayashi, S; Murray, S; Sesardic, D; Watson, D | 1 |
| Bilston, RA; David, R; Firkin, BG; Logan, D; Pfueller, SL; Sloan, IG | 1 |
| Marcus, DC; Wangemann, P | 1 |
| Bunnag, D; Chittamas, S; Harinasuta, T; Looareesuwan, S; White, NJ | 1 |
| Bilston, RA; Firkin, BG; Gibson, JM; Logan, D; Pfueller, SL | 1 |
| Attanath, P; Chanthavanich, P; Chongsuphajaisiddhi, T; Sabchareon, A; Sinhasivanon, V | 1 |
| Brubaker, G; Draper, CC; Hills, M; Kilimali, VA | 1 |
| Crewe, HK; Lennard, MS; Otton, SV; Tucker, GT; Woods, HF | 1 |
| Jamaludin, A; Mohamed, M; Mohamed, N; Navaratnam, V; Wernsdorfer, W; Yeoh, E | 1 |
| Berthe, J; Brandicourt, O; Chongsuphajaisiddhi, T; Druilhe, P | 1 |
| Berth, J; Bunnag, D; Chittamas, S; Druilhe, P; Harinasuta, T; Looareesuwan, S; Punnavut, W; Vanijanonta, S | 1 |
| Bhasin, VK; Trager, W | 1 |
| Buregea, H; Cibanguka, J; Delacollette, C; Nkera, J | 1 |
| Bunnag, D; Harinasuta, T | 1 |
| Smit, EH | 1 |
| Allan, EJ; Scragg, AH | 1 |
| White, NJ | 1 |
| L'Estrange Orme, M | 1 |
| Gioeli, C; Pettersson, C | 1 |
| Christie, DJ; Cook, JM; Diaz-Arauzo, H | 1 |
| Ching, MS; Klejn, MB; Mihaly, GW; Paull, J; Smallwood, RA | 1 |
| Bjellerup, M; Ljunggren, B | 1 |
| Boobis, AR; Davies, DS; Murray, S; Seddon, CE; Speirs, CJ | 1 |
| Pfeifer, S; Pöhlmann, H; Theil, FP | 1 |
| Hardy, KJ; Hyman, KM; Mihaly, GW; Smallwood, RA | 1 |
| Al-Abdulla, IH; Landon, J; Rowell, FJ; Sidki, AM | 1 |
| Aster, RH; Christie, DJ; Mullen, PC | 2 |
| Fujimura, K; Matsuda, Y; Yoshida, S | 1 |
| Drayer, DE; Metakis, L; Notterman, DA; Reidenberg, MM | 1 |
| Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y; Suzuki, H | 1 |
| Jones, CE; Jordan, JV; Kautz, CA; Reid, DM; Shulman, NR; Smith, ME | 1 |
| Berndt, MC; Bull, HA; Castaldi, PA; Chong, BH; Zola, H | 1 |
| Hall, AP; Peters, W | 1 |
| Diwan, JJ | 1 |
| Bramham, S; Morgan, MR; Rhodes, MJ; Robins, RJ; Webb, AJ | 1 |
| Holmes, J; Sapeika, N; Zwarenstein, H | 2 |
| Askari, A; Lowry, K; Pitts, BJ; Rao, SN | 1 |
| Pesce, A; Rugiero, G | 1 |
| Sellers, E; Weser, JK | 1 |
| Achari, G; Banerji, PK; Kapoor, K | 1 |
| Araki, Y | 1 |
| Hrivnák, J; Sarsŭnová, M | 1 |
| Dumas, M; Girard, PL; N'Diaye, IP | 1 |
| Alvarez Sotolongo, M; Krácmar, J; Krácmarová, J | 1 |
| Brener, Z; Brossi, A; Gutzwiller, J; Krettli, AU; Uskoković, M | 2 |
| Haller, R; Schneider, HJ | 1 |
| Armand, J; Badinand, A | 1 |
| Vinczéné, VM | 1 |
| Barkan, S; Levine, J; Maienthal, M; Ross, B; Smith, E | 1 |
| Vincze, Z; Vincze-Vermes, M | 1 |
| Hall, WH; Schlutz, M; Zinneman, HH | 1 |
| Barker, JD; Christensen, J | 1 |
| Capomacchia, AC; Paul, WL; Schulman, SG; Threatte, RM | 1 |
| Erdmann, H; Heimpel, H | 1 |
| Grethe, G; Gutzwiller, J; Lee, HL; Uskoković, MR | 1 |
| Klepzig, H | 1 |
| Böttiger, LE; Westerholm, B | 1 |
| Crowell, EB; Eisner, EV | 1 |
| Auterhoff, H; Pankow, HJ | 1 |
| Bitsch, R; Böhme, H | 1 |
| Jacobsen, CD | 1 |
| Bafna, SL; Bhat, CV; Kamath, BR; Kanhere, SS; Shah, RS; Vyas, AH | 1 |
| Gerhardt, RE; Knouss, RF; Luchi, RJ; Morris, JJ; Thyrum, PT | 1 |
| Ball, EG; Markus, HB | 1 |
| Gutzwiller, J; Henderson, T; Uskoković, M | 1 |
| Gutzwiller, J; Uskoković, M | 1 |
| Dunning, AJ; Kettner, H; Muller, EJ | 1 |
| Chou, SC; Conklin, KA; Heu, P | 1 |
| Olech, A | 1 |
| Peter, JB; Worsfold, M | 1 |
| Stenberg, VI; Travecedo, EF | 1 |
| Kaye, S | 1 |
| Boulos, BM; Davis, LE; Short, CR | 1 |
| Balwani, JH; Kulkarni, SD; Phansalkar, AG | 1 |
| Bright, RE; Rane, L; Rees, RW; Russell, PB; Smith, H; Yardley, JP | 1 |
| Barstad, JA | 1 |
| Fedyshin, PS; Furkalo, NK; Korkushko, OV; Radzivil, VF | 1 |
| Bafna, SL; Kanhere, SS; Shah, RS | 1 |
| Musa, WE; Stenberg, VI; Travecedo, EF | 1 |
| Baggett, B; Martin, B; Palmer, KH; Wall, ME | 1 |
| Brochmann-Hanssen, E; Fontan, CR | 1 |
| French, WN; Morrison, JC | 1 |
| Berndt, MC; Caen, JP | 1 |
| Caldwell, RW; Elam, JT; Mecca, TE; Nash, CB | 1 |
| Ilett, KF; Minchin, RF | 1 |
| Bunnag, D; Chongsuphajaisiddhi, T; Harinasuta, T; Looareesuwan, S; Warrell, DA; White, NJ | 1 |
| Inaba, T; Kalow, W; Otton, SV | 1 |
| Danielson, DA; Douglas, SW; Herzog, P; Jick, H; Porter, JB | 1 |
| Hartung, K; Hermann, A | 1 |
| Aster, RH; Christie, DJ | 1 |
| Fishman, MC; Spector, I | 1 |
| Okada, Y; Tsuchiya, W; Yada, T | 1 |
| Aster, RH; Christie, DJ; Kunicki, TJ | 1 |
| Rieckmann, KH | 1 |
| Balasubramanian, D; Mohan Rao, C; Panijpan, B | 1 |
| Chiodini, PL; Ellis, CJ | 1 |
| Clancy, R; Danis, V; Trent, R | 1 |
| Moss, RA | 1 |
| Boman, A; Wahlberg, JE | 1 |
| Kalow, W; Otton, SV; Seeman, P | 1 |
| Aster, RH; Christie, DJ; Cook, JM; Mullen, PC; Weber, RW | 1 |
| Awazu, S; Hayashi, M; Yokosuka, I | 1 |
| Abraham, I; Ueda, CT | 1 |
| Blaschke, TF; Schulz, P | 1 |
| Firkin, BG; Hosseinzadeh, PK; Pfueller, SL | 2 |
| Scott, B | 1 |
| Jones, MT; Sideropoulos, AS; Specht, SM | 1 |
| Koller, CA | 1 |
| Engelfriet, CP; van Leeuwen, EF; von dem Borne, AE | 1 |
| Patel, CP | 1 |
| Fisher, CM | 1 |
| Bailey, JC; Mirro, MJ; Watanabe, AM | 1 |
| Bhuwapathanapun, S; Christopher, RK; Duffield, AM; Graham, GG; Liddle, C | 1 |
| Vincent, PC | 1 |
| Barrow, SE; Horning, EC; Horning, MG; Taylor, AA | 1 |
| Massing, GK; Mockridge, PB; Wilkerson, RD | 1 |
| Breithardt, G; Haerten, K; Seipel, L | 1 |
| Aster, RH; Caen, JP; Kunicki, TJ; Nurden, AT; Russell, N | 1 |
| Chambers, M; Li, CQ; López, JA; Weisman, S | 1 |
| Malchow, RP; Qian, H; Ripps, H | 1 |
| Bunker, CH; Day, BW; Hopp, L | 1 |
| Díaz, M; Sepúlveda, FV | 1 |
| Bird, MR; Buchanan, RR; Des Parkin, J; Ibrahim, KM; O'Neill, AI | 1 |
| Cook, DI; Hayashi, T; Hirono, C; Young, JA | 1 |
| Snyders, DJ; Yeola, SW | 1 |
| Diaz, J; Muallem, S; Xu, X; Zhao, H | 1 |
| Cook, DI; Ishikawa, T | 1 |
| Gundert-Remy, U; Meineke, I; Rohde, S | 1 |
| Haugh-Scheidt, LM; Malchow, RP; Qian, H; Ripps, H | 1 |
| Huang, Y; Masubuchi, Y; Mizukami, T; Narimatsu, S; Suzuki, T | 2 |
| Herr, GP; Stroncek, DF | 1 |
| Adragna, NC; Lauf, PK | 1 |
| Patterson, FK; Wigler, PW | 1 |
| Cook, JM; Diaz-Araúzo, H; La Loggia, AJ; Lyon, KL; Patterson, FK; Reddy, MS; Wigler, PW | 1 |
| Bendayan, R; Lo, B; Silverman, M | 1 |
| Bode, AP; Boshkov, LK; Hayward, CP; Kelton, JG; Santos, AV; Sheppard, JA; Warkentin, TE | 1 |
| Bochner, F; Chen, ZR; Somogyi, AA | 1 |
| Bruze, M; Gruvberger, B; Isaksson, M; Ljunggren, B | 1 |
| Hasler, JA; Masimirembwa, CM | 1 |
| Augeron, C; Guo, X; Hopfer, U; Laboisse, CL; Merlin, D; Tien, XY | 1 |
| Hyman, MK; Mihaly, GW; Morgan, DJ; Scott, H; Smallwood, RA | 1 |
| Barham, HM; Lennard, MS; Tucker, GT | 1 |
| Kario, K; Matsuo, T | 1 |
| Escobar, MR; Sitar, DS; Smyth, DD; Wong, LT | 1 |
| Christie, DJ; Fairbanks, KD; Kay, NE; Sauro, SC | 1 |
| Aoki, FY; Gaudry, SE; McKenzie, JK; Sitar, DS; Smyth, DD | 1 |
| Kanakubo, Y; Kitada, M; Kiuchi, M; Ohmori, S; Rikihisa, T; Takeda, S | 1 |
| Babalola, CP; Bolaji, OO; Dixon, PA; Ogunbona, FA | 1 |
| Bunnag, D; Davis, TM; Karbwang, J; Looareesuwan, S; Molunto, P; White, NJ | 1 |
| Schubarth, P | 1 |
| Coville, PF; Walker, RJ; Wanwimolruk, S; Wong, SM; Zhang, H | 1 |
| Engel, AG; Milone, M; Sieb, JP | 1 |
| del Pozo, BF; Pérez-Vizcaíno, F; Tamargo, J; Villamor, E; Zaragozá, F | 1 |
| Droogmans, G; Nilius, B; Voets, T | 1 |
| Abou-Donia, MB; Ayad, HM; Corcoran, JJ; Fine, RL; Lanning, CL; Rose, RL | 1 |
| Krishna, S; White, NJ | 1 |
| Gawdi, G; Misra, UK; Pizzo, SV | 1 |
| Karle, JM | 1 |
| Birkett, DJ; Coville, PF; Miners, JO; Walker, RJ; Wanwimolruk, S; Zhang, H | 1 |
| Chow, T; Funae, Y; Hiroi, T; Imaoka, S; Yabusaki, Y | 1 |
| Attali, B; Cherepanov, V; Kolot, A; Sobko, A; Soliven, B; Wang, N | 1 |
| Akaike, N; Kakehata, S; Saito, H; Saito, T; Yamada, T; Yamamoto, T | 1 |
| Kudo, S; Odomi, M; Umehara, K | 1 |
| Ishizaki, T; Kawashiro, T; Zhao, XJ | 1 |
| Hedman, A; Meijer, DK | 2 |
| Newton, CR; Warrell, DA | 1 |
| Ericsson, O; Gustafsson, LL; Mirghani, RA | 1 |
| Aster, RH; Newman, PJ; Peterson, JA; Visentin, GP | 1 |
| Aster, RH; Curtis, BR; Gentilini, G | 1 |
| Clement, EM; Elliott, JM; Grahame-Smith, DG | 1 |
| Tu, ZG; Zhao, LL | 1 |
| Wright, SH; Wunz, TM | 1 |
| Burgel, PR; Camara, P; Hovette, P; Klotz, F; Mbaye, PS; Sane, M | 1 |
| Fujita, S; Funae, Y; Hirota, T; Imaoka, S; Kazusaka, A; Masuda, M; Morino, A; Nakamura, A; Tasaki, T; Yamamoto, Y | 1 |
| Clauss, W; Heinke, B | 1 |
| Alván, G | 1 |
| Lämmerhofer, M; Lindner, W; Maier, NM; Nicoletti, L | 1 |
| Morino, A; Mukai, H | 1 |
| Chalcroft, SC; Coville, PF; Ho, PC; Wanwimolruk, S | 1 |
| Brasch, F; Falk, S; Göggel, R; Heydasch, U; Müller, KM; Uhlig, S; Wendel, A | 1 |
| Bertilsson, L; Ericsson, O; Gustafsson, LL; Hellgren, U; Mirghani, RA; Westerberg, PA | 1 |
| Blackburn, MG; Ellis, SW; Harlow, J; Hayhurst, GP; Larsson, C; Lennard, MS; Lightfoot, T; Lim, CK; Mahling, J; Rowland-Yeo, K; Smith, G; Tucker, GT; Wolf, CR | 1 |
| Chiba, M; Lin, JH; Lin, Y; Neway, W; Nishime, JA | 1 |
| Dasgupta, A; Paul, A; Wells, A | 1 |
| Bachhawat, K; Surolia, A; Surolia, N; Thomas, CJ | 1 |
| Crommen, J; Lindner, W; Piett, V | 1 |
| Cook, J; Ericsson, O; Gustafsson, LL; Mirghani, RA; Yu, P | 1 |
| Franco, P; Lämmerhofer, M; Lindner, W; Petracs, M; Zarbl, E | 1 |
| Cooper, RA; Ferdig, MT; Fidock, DA; Fujioka, H; Mu, J; Nomura, T; Roepe, PD; Su, XZ; Ursos, LM; Wellems, TE | 1 |
| Cheze, S; Leporrier, M | 1 |
| Angus, PW; Blake, CL; Ching, MS; Ghabrial, H; Malek, NA | 1 |
| Hasler, JA; Mannervik, B; Mukanganyama, S; Naik, YS; Widersten, M | 1 |
| Heegsma, J; Hooiveld, GJ; Jansen, PL; Meijer, DK; Müller, M; van Montfoort, JE | 1 |
| Karle, IL; Karle, JM | 1 |
| Gelboin, HV; Gonzalez, FJ; Granvil, CP; Idle, JR; Krausz, KW | 1 |
| Beijer, FH; de Vries, JG; Lambers, M; Padron, JM; Toth, I | 1 |
| De Dios, AC; DuBay, K; Leed, A; Roepe, PD; Sears, D; Ursos, LM | 1 |
| Michel, D; Nawrath, H; Wegener, JW | 1 |
| Jantra, A; Pitisuttithum, P; Pukrittayakamee, S; Wanwimolruk, S; White, NJ; Zhang, H | 1 |
| Cook, JM; Ericsson, O; Gustafsson, LL; Mirghani, RA; Tybring, G; Yasar, U; Zheng, T | 1 |
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| Paine, MF; Pusek, SN; Wanwimolruk, S; Watkins, PB | 1 |
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| Hutzler, JM; Walker, GS; Wienkers, LC | 1 |
| Bertilsson, L; Ericsson, O; Gustafsson, LL; Mirghani, RA; Tybring, G | 1 |
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| MALONE, MH; RAGOZZINO, PW | 2 |
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| Emerson, LR; Kuchler, K; Skillman, BC; Wirth, DF; Wolfger, H | 1 |
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| Jin, F; Lu, BZ; Senanayake, CH; Wald, SA; Wu, X; Zhang, Y | 1 |
| Brzostowski, JA; Kimmel, AR; Naudé, B; Wellems, TE | 1 |
| Ballestero, JA; Elgoyhen, AB; Gómez-Casati, ME; Katz, E; Kracun, S; Millar, NS; Plazas, PV; Rothlin, CV; Taranda, J | 1 |
| Cook, JM; Deschamps, JR; Han, D; Srirama Sarma, PV | 1 |
| Nomura, S | 1 |
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| Armand, V; Avoli, M; D'Antuono, M; Devaux, B; Gigout, S; Kawasaki, H; Kurcewicz, I; Laschet, J; Louvel, J; Olivier, A; Pumain, R; Turak, B | 1 |
| Andresen H, M; Baudrand B, R; Guzmán D, AM; Labarca L, J; Pérez C, C; Perret P, C | 1 |
| Huston, M; Levinson, M | 1 |
| Klitgaard, H; Margineanu, DG | 1 |
| Nitek, W; Oleksyn, BJ; Tesarowicz, I | 1 |
| Cooper, RA; Deng, B; Ferdig, MT; Lane, KD; Mu, J; Patel, JJ; Su, X; Wellems, TE | 1 |
| Abdelrahim, II; Adam, I; Elbashir, MI; Elghazali, G; Gustafsson, LL; Mirghani, RA | 1 |
| Fueger, JT; Gottschall, JL; Johnson, ST | 1 |
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| Ansari, MJ; Garapati, S; Iroegbu, N; Okoli, O; Spear, JB; Wongba, W | 1 |
| Bui, T; Ho, RJ; Hsiao, P; Unadkat, JD | 1 |
| Margolskee, RF; Nilius, B; Ninomiya, Y; Talavera, K; Voets, T; Yasumatsu, K; Yoshida, R | 1 |
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| Blue, D; Cruz, J; Graves, V; Gregurek, S; McCarthy, L; Smith, D | 1 |
| Julínek, O; Lindner, W; Urbanová, M | 2 |
| BRAVEMAN, BL; KORANSKY, DS; KULVIN, MM | 1 |
| KEOGH, P; MacCALLUM, M; SHAW, FH | 1 |
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| Ai, C; Chen, Y; Li, Y; Wang, Y; Yang, L | 1 |
| Inazu, M; Matsumiya, T; Tajima, H; Takeda, H; Uchida, Y; Yamada, T | 1 |
| Omoruyi, SI; Onyeji, CO; Soyinka, JO | 1 |
| Jacobson, G; Sleigh, JW; Steyn-Ross, A; Steyn-Ross, M; Voss, LJ | 1 |
| Almeida, GT; Corrêa Soares, JB; Egan, TJ; Ferreira-Pereira, A; Hunter, R; Kuter, D; Menezes, D; Oliveira, MF; Vannier-Santos, MA; Venancio, TM; Verjovski-Almeida, S; Zishiri, VK | 1 |
| Aggarwal, VK; Arshad, M; Illa, O; McGarrigle, EM; Ros, A | 1 |
| Becker, R; Katus, HA; Schweizer, PA; Thomas, D | 1 |
| Cook, JM; Omoruyi, SI; Onyeji, CO; Owolabi, AR; Sarma, PV; Soyinka, JO | 1 |
| Brunklaus, G; Enkelmann, V; Khan, M | 1 |
| ALEXANDER, F; GOLD, H | 1 |
| Aklillu, E; Gustafsson, LL; Mukonzo, JK; Ogwal-Okeng, J; Waako, P | 1 |
| Pendleton, RC; Rondina, MT; Walker, A | 1 |
| Smereck, J | 1 |
| Levkin, PA; Lindner, W; Maier, NM; Schurig, V | 1 |
| DE, P | 1 |
| GEILING, EM; KELSEY, FE; OLDHAM, FK | 1 |
| Kimura, M; Kinoshita, A; Kotaki, H; Yamada, H | 1 |
| Ahmadi, KR; Heaton, J; Legido-Quigley, C; Rahmioglu, N; Smith, NW | 1 |
| Ahmadi, KR; Clement, G; Gill, R; Heaton, J; Hider, RC; Hodgkiss, D; Ma, Y; Rahmioglu, N; Smith, NW; Surdulescu, G; Zlobecka, K | 1 |
| Blanckaert, A; Chemat, F; Elomri, A; Fabiano-Tixier, AS; Petitcolas, E; Seguin, E | 1 |
| de Villiers, KA; Gildenhuys, J; le Roex, T | 1 |
| Epstein, DH; Hirsch, GA; Phillips, KA; Preston, KL | 1 |
| Bouchet, A; Le Barbu-Debus, K; Lepère, V; Piuzzi, F; Scuderi, D; Sen, A; Zehnacker-Rentien, A | 1 |
| Ahmadi, KR; Clement, G; Gill, R; Heaton, J; Hodgkiss, D; Rahmioglu, N; Smith, NW; Surdulescu, G; Zlobecka, K | 1 |
| de Dios, AC; Gorka, AP; Roepe, PD; Sherlach, KS | 1 |
| Dwivedi, H; Pandey, SK; Siddiqui, WA; Singh, S; Tripathi, R | 1 |
| Guerin, PM; Kessler, S; Vlimant, M | 1 |
| Arceo, E; Bravo, F; Cassani, C; Martín-Rapún, R; Melchiorre, P | 1 |
| Heemstra, JM; Spiropulos, NG | 1 |
| Edmund, GH; Howlin, BJ; Lewis, DF | 1 |
| Gargano, AF; Kohout, M; Lämmerhofer, M; Lindner, W; Macíková, P | 1 |
| Hellinger, R; Horak, J; Lindner, W | 1 |
| Meyers, DJ; Sanders, NG; Sullivan, DJ | 1 |
| Doumbo, OK; Guirou, EA; Hendrix, CW; Kayentao, K; Nyunt, MM; Parsons, TL; Plowe, CV; Venkatesan, M | 1 |
| Alpizar, YA; Bultynck, G; Gees, M; Luyten, T; Nilius, B; Parys, JB; Talavera, K; Voets, T | 1 |
| Ke, Y; Liang, X; Song, G; Wang, D; Wu, H | 1 |
| Andersson, TB; Bäckström, T; Bertilsson, L; Björkhem-Bergman, L; Bredberg, E; Diczfalusy, U; Nylén, H; Rönquist-Nii, Y | 1 |
| Aranyi, A; Fülöp, F; Grecsó, N; Ilisz, I; Lindner, W; Misicka, A; Péter, A; Suchotin, P; Tymecka, D; Wilenska, B | 1 |
| Hettegger, H; Kohout, M; Lindner, W; Mimini, V | 1 |
| Cai, L; Chen, M; Lin, J; Liu, Y; Song, L; Wang, S | 1 |
| Cyrklaff, M; Ferdig, MT; Lanzer, M; Liu, CH; Mayer, S; Mu, J; Nurhasanah, A; Sanchez, CP; Stein, WD | 1 |
| Akanmu, MA; Cook, JM; Igbinoba, SI; Nathaniel, TI; Onyeji, CO; Pullela, SS; Soyinka, JO | 1 |
| Bellanca, S; Dave, A; Dittmer, M; Lanzer, M; Martin, RE; Meyrath, M; Nash, MN; Sanchez, CP; Stein, WD; Summers, RL | 1 |
| Huang, YP; Liu, ZS; Zhang, C; Zhang, J | 1 |
| Lippiat, JD; Muench, SP; Wrighton, DC | 1 |
| de Villiers, KA; Gildenhuys, J; Kuter, D; le Roex, T; Müller, R; Sammy, CJ; Streltsov, VA | 1 |
| Agusta, A; Kitamura, C; Maehara, S; Ohashi, K; Shibuya, H | 1 |
| Calderón, C; Horak, J; Lämmerhofer, M | 1 |
| Sutherland, CJ | 1 |
| Calderón, C; Lämmerhofer, M | 1 |
| Bilonda, MK; Mammino, L | 1 |
| Niwa, T; Shizuku, M; Yamano, K | 1 |
| Akbarsha, MA; Karthikeyan, BS; Parthasarathy, S; Suvaithenamudhan, S | 1 |
| Hoye, TR; Ross, SP | 1 |
| Frelek, J; Górecki, M; Groszek, G | 1 |
| Ganzera, M; Murauer, A | 1 |
| Alemán Valls, R; Lorenzo Morales, J; Losada Castillo, MJ; Rocha Cabrera, P; Rodríguez Talavera, I | 1 |
| Daniels, CE; King, RL; Ripoll, JG; Rizvi, MS | 1 |
| Browne, T; Conti, T; Fiorentin, TR; Krotulski, AJ; Logan, BK; Martin, DM; Triplett, J | 1 |
| Horak, J; Lämmerhofer, M | 1 |
| Rosenthal, PJ; Tan, KR | 1 |
| Bonnaillie, P; Brouta, F; Chanteux, H; Gillent, E; Helmer, E; Long, J; Mathy, FX; Nicolaï, J; Nicolas, JM; Rosseels, ML; Viot, D | 1 |
| Alföldi, R; Gyuris, M; Hackler, L; Huzián, O; Kanizsai, I; Knapp, L; Madácsi, R; Puskás, LG; Szebeni, GJ | 1 |
| Cagnon, BR; Mohammadlou, A; Wulff, WD; Yin, X; Zheng, L | 1 |
| Antonchick, AP; Burhop, A; Foley, DJ; Gally, JM; Grigalunas, M; Mantel, Y; Pahl, A; Scheel, R; Sievers, S; Strohmann, C; Waldmann, H; Wild, N; Zinken, S | 1 |
| Kawai, T; Kuninishi, Y; Muraki, Y; Nogawa, H | 1 |
| Christini, DJ; Clark, AP; Kalola, D; Krogh-Madsen, T; Wei, S | 1 |
| Ahmed, SB; Al-Buriahi, MS; Alrowaili, ZA; Birmani, PR; Ejaz, SA; Elqahtani, ZM; Katubi, KM; Saeed, A; Siddique, F; Ujan, R | 1 |
31 review(s) available for quinidine and quinine
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The plasma membrane monoamine transporter (PMAT): Structure, function, and role in organic cation disposition.
Topics: Animals; Biogenic Amines; Humans; Plasma Membrane Neurotransmitter Transport Proteins; Xenobiotics | 2016 |
TASK Channels Pharmacology: New Challenges in Drug Design.
Topics: Animals; Drug Design; Drug Discovery; Humans; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Tandem Pore Domain | 2019 |
Pharmacology of hearing and ototoxicity.
Topics: Adrenal Glands; Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bumetanide; Cochlea; Environmental Pollutants; Erythromycin; Ethacrynic Acid; Female; Furosemide; Guinea Pigs; Hearing; Hearing Disorders; Humans; Kidney; Ovary; Quinidine; Quinine; Seizures; Thyroid Gland | 1978 |
Thrombocytopenia.
Topics: Alcoholism; Antibiotics, Antineoplastic; Autoimmune Diseases; Bacterial Infections; Blood Platelets; Blood Transfusion; Bone Marrow Diseases; Cell Survival; Gold; Humans; Quinidine; Quinine; Splenomegaly; Thrombocytopenia | 1976 |
Inhibition of desipramine 2-hydroxylation by quinidine and quinine in rapid and slow debrisoquine hydroxylators.
Topics: Debrisoquin; Depression, Chemical; Desipramine; Humans; Hydroxylation; Isoquinolines; Phenotype; Quinidine; Quinine | 1989 |
Quinine and quinidine in malaria in Thailand.
Topics: Humans; Malaria; Quinidine; Quinine; Thailand | 1987 |
Quinine is not what it used to be....
Topics: Animals; Cinchona Alkaloids; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Quinidine; Quinine | 1987 |
The potential of plant cell culture for the production of quinine.
Topics: Cells, Cultured; Cinchona; Plants, Medicinal; Quinidine; Quinine | 1987 |
The pharmacokinetics of quinine and quinidine in malaria.
Topics: Humans; Malaria; Quinidine; Quinine | 1987 |
Side effects of quinine and derivatives.
Topics: Humans; Malaria; Quinidine; Quinine | 1987 |
Systemic drug photosensitivity.
Topics: Amiodarone; Animals; Anti-Inflammatory Agents; Benzodiazepines; Benzofurans; Griseofulvin; Humans; Nalidixic Acid; Phenothiazines; Photosensitivity Disorders; Quinidine; Quinine; Sulfonamides; Tetracyclines | 1986 |
Drug interactions with coumarin anticoagulants. 2.
Topics: Allopurinol; Anabolic Agents; Animals; Anti-Bacterial Agents; Anticoagulants; Barbiturates; Chloral Hydrate; Chloramphenicol; Cholestyramine Resin; Clofibrate; Contraceptives, Oral; Coumarins; Dextrothyroxine; Diuretics; Drug Antagonism; Drug Synergism; Ethacrynic Acid; Ethanol; Glucagon; Glucocorticoids; Glutethimide; Humans; Oxyphenbutazone; Phenylbutazone; Quinidine; Quinine; Quinolines; Salicylates; Sulfinpyrazone; Sulfonamides; Thyroid Hormones; Tolbutamide | 1971 |
[Drug-induced jaundice].
Topics: Acetanilides; Aminosalicylic Acids; Benzenesulfonates; Bilirubin; Biological Transport; Cholestasis; Drug Hypersensitivity; Hepatitis; Humans; Jaundice; Liver; Microsomes, Liver; Phenacetin; Quinidine; Quinine; Sulfasalazine; Sulfones | 1972 |
[Asymmetrical reactions].
Topics: Aluminum; Catalysis; Chemical Phenomena; Chemistry; Enzyme Induction; Ephedrine; Estradiol; Isomerism; Ketones; Kinetics; Lithium; Oxidation-Reduction; Quinidine; Quinine; Stereoisomerism; Structure-Activity Relationship | 1973 |
Platelet glycoproteins.
Topics: Antibodies; Blood Platelets; Calpain; Endopeptidases; Factor VIII; Glycoproteins; Hemorrhagic Disorders; Humans; Membrane Proteins; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Quinidine; Quinine; Receptors, Cell Surface; Receptors, Immunologic; Receptors, Thrombin; Syndrome; Thrombocytopenia | 1984 |
Ca2+ activated K+ conductance in molluscan neurones.
Topics: Action Potentials; Animals; Apamin; Aplysia; Binding Sites; Caffeine; Calcium; Electric Conductivity; Gallamine Triethiodide; Helix, Snails; Ion Channels; Membrane Potentials; Mollusca; Neurons; Photoreceptor Cells; Potassium; Quinidine; Quinine; Ruthenium Red; Tetraethylammonium Compounds | 1983 |
Falciparum malaria: the urgent need for safe and effective drugs.
Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Sulfadoxine | 1983 |
Drug-induced immune thrombocytopenia.
Topics: Antibody Specificity; Heparin; Heroin; Humans; Immune Complex Diseases; Immune System Diseases; Quinidine; Quinine; Thrombocytopenia | 1980 |
Immune thrombocytopenic purpura.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antibodies; Autoimmune Diseases; Blood Platelets; Child; Child, Preschool; Chronic Disease; Female; Humans; Infant, Newborn; Isoantibodies; Male; Platelet Count; Purpura, Thrombocytopenic; Quinidine; Quinine; Splenectomy; Transfusion Reaction | 1980 |
[Malaria: the most important emergency in subjects returning from the tropics].
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Emergencies; Humans; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium; Pyrimethamine; Quinidine; Quinine; Sulfadoxine | 1993 |
Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Interactions; Drug Therapy, Combination; Malaria, Falciparum; Molecular Conformation; Quinidine; Quinine | 1996 |
Neurological manifestations of falciparum malaria.
Topics: Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Humans; Malaria, Cerebral; Quinidine; Quinine; Sesquiterpenes | 1998 |
[Immuno-allergic cytopenias].
Topics: Agranulocytosis; Anti-Bacterial Agents; Antimalarials; Diagnosis, Differential; Drug Hypersensitivity; Humans; Lactams; Quinidine; Quinine; Recurrence; Risk Factors; Thrombocytopenia | 2001 |
Emerging drug--resistance and guidelines for treatment of malaria.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors | 2004 |
[Definition and mechanism of drug-induced thrombocytopenia].
Topics: Anticoagulants; Autoantibodies; Benzothiadiazines; Blood Platelets; Diagnosis, Differential; Diuretics; Heparin; Humans; Megakaryocytes; Purpura, Thrombocytopenic, Idiopathic; Quinidine; Quinine; Sodium Chloride Symporter Inhibitors; Thrombocytopenia | 2005 |
Are one or two dangerous? Quinine and quinidine exposure in toddlers.
Topics: Child, Preschool; Dose-Response Relationship, Drug; Drug Overdose; Humans; Infant; Poison Control Centers; Quinidine; Quinine; United States | 2006 |
Solution phase enantioselective recognition and discrimination by electrospray ionization--mass spectrometry: state-of-the-art, methods, and an eye towards increased throughput measurements.
Topics: Calorimetry; Chromatography, High Pressure Liquid; Combinatorial Chemistry Techniques; Molecular Structure; Quinidine; Quinine; Solutions; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Time Factors | 2007 |
[Drug-induced thrombocytopenia].
Topics: Abciximab; Antibodies, Monoclonal; Carbamazepine; Gold Compounds; Heparin; Humans; Immunoglobulin Fab Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Procainamide; Quinidine; Quinine; Rifampin; Thrombocytopenia; Time Factors | 2007 |
Cardiac complications of unwitting co-injection of quinine/quinidine with heroin in an intravenous drug user.
Topics: Adult; Arrhythmias, Cardiac; Drug Contamination; Drug Users; Electrocardiography; Follow-Up Studies; Heroin Dependence; Humans; Male; Quinidine; Quinine; Risk Assessment; Substance Abuse, Intravenous | 2012 |
15 trial(s) available for quinidine and quinine
| Article | Year |
|---|---|
Pharmacokinetics of quinine, quinidine and Cinchonine when given as combination.
Topics: Adult; Antimalarials; Cinchona Alkaloids; Drug Combinations; Humans; Malaria, Falciparum; Male; Quinidine; Quinine; Treatment Outcome | 1992 |
Red cell and plasma concentrations of combined quinine-quinidine and quinine in falciparum malaria.
Topics: Antimalarials; Child; Child, Preschool; Cinchona Alkaloids; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation; Erythrocytes; Female; Humans; Malaria, Falciparum; Male; Plasma; Quinidine; Quinine | 1991 |
Susceptibility of Plasmodium falciparum to different doses of quinine in vivo and to quinine and quinidine in vitro in relation to chloroquine in Liberia.
Topics: Animals; Child; Child, Preschool; Drug Resistance; Humans; Infant; Liberia; Malaria, Falciparum; Plasmodium falciparum; Quinidine; Quinine | 1991 |
Gender and age as factors in the inhibition of renal clearance of amantadine by quinine and quinidine.
Topics: Adult; Aged; Aging; Amantadine; Analysis of Variance; Drug Interactions; Female; Humans; Kidney; Male; Middle Aged; Quinidine; Quinine; Reference Values; Sex Characteristics | 1993 |
A comparison of the pharmacokinetic and pharmacodynamic properties of quinine and quinidine in healthy Thai males.
Topics: Adult; Electrocardiography; Half-Life; Hearing Loss; Hemodynamics; Humans; Infusions, Intravenous; Male; Quinidine; Quinine; Thailand | 1993 |
Grapefruit juice has no effect on quinine pharmacokinetics.
Topics: Antimalarials; Beverages; Chromatography, High Pressure Liquid; Citrus; Cross-Over Studies; Drug Interactions; Humans; Male; Quinidine; Quinine | 1999 |
The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo.
Topics: Adult; Antifungal Agents; Antimalarials; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Fluvoxamine; Humans; Hydroxylation; Ketoconazole; Male; Mixed Function Oxygenases; Quinidine; Quinine; Selective Serotonin Reuptake Inhibitors | 1999 |
Effects of cigarette smoking on quinine pharmacokinetics in malaria.
Topics: Acute Disease; Adult; Antimalarials; Humans; Malaria, Falciparum; Male; Quinidine; Quinine; Smoking | 2002 |
Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4?
Topics: Administration, Oral; Adult; Aged; Antimalarials; Area Under Curve; Breath Tests; Cross-Over Studies; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Erythromycin; Female; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Molecular Probes; Ovarian Neoplasms; Quinidine; Quinine; Troleandomycin | 2002 |
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.
Topics: Adult; Biomarkers; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluvoxamine; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Male; Middle Aged; Quinidine; Quinine | 2003 |
Metabolism and elimination of quinine in healthy volunteers.
Topics: Antimalarials; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Ketoconazole; Mixed Function Oxygenases; Quinidine; Quinine; Quinones; Time Factors | 2003 |
Pharmacokinetics of quinine and its metabolites in pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria.
Topics: Antimalarials; Area Under Curve; Female; Half-Life; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Quinidine; Quinine; Sudan | 2007 |
Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration.
Topics: Administration, Oral; Adult; Aged; Anti-HIV Agents; Antimalarials; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Male; Middle Aged; Quinidine; Quinine; Ritonavir | 2010 |
Quinine compared to 4β-hydroxycholesterol and midazolam as markers for CYP3A induction by rifampicin.
Topics: Biomarkers; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Dose-Response Relationship, Drug; Healthy Volunteers; Humans; Hydrocortisone; Hydroxycholesterols; Midazolam; Quinidine; Quinine; Rifampin | 2014 |
Effect of dehusked Garcinia kola seeds on the overall pharmacokinetics of quinine in healthy Nigerian volunteers.
Topics: Administration, Oral; Adult; Area Under Curve; Biotransformation; Chromatography, High Pressure Liquid; Cross-Over Studies; Dietary Supplements; Drug Interactions; Female; Garcinia kola; Half-Life; Healthy Volunteers; Humans; Male; Metabolic Clearance Rate; Nigeria; Quinidine; Quinine; Seeds; Therapeutic Equivalency; Young Adult | 2015 |
433 other study(ies) available for quinidine and quinine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies.
Topics: Alkaloids; Computer Simulation; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Ethanolamines; Humans; Indoles; Microsomes, Liver; Mixed Function Oxygenases; Models, Molecular; Molecular Conformation; Molecular Structure; Quinidine; Quinolines; Secologanin Tryptamine Alkaloids; Yohimbine | 1993 |
Monoamine neurotransmitter transport mediated by the polyspecific cation transporter rOCT1.
Topics: Acetylcholine; Animals; Biogenic Monoamines; Carrier Proteins; Cell Line; Cloning, Molecular; Dopamine; Female; Histamine; Humans; Kidney; Kidney Tubules, Proximal; Kinetics; Liver; Membrane Potentials; Membrane Proteins; Oocytes; Organic Cation Transporter 1; Rats; Recombinant Proteins; Serotonin; Transfection; Xenopus laevis | 1996 |
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
Topics: Animals; Base Sequence; Biological Transport; Carrier Proteins; Cations; Choline; Electric Conductivity; Kidney; Lidocaine; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Niacinamide; Organic Cation Transporter 1; Pyridinium Compounds; Rats; Recombinant Proteins; Substrate Specificity | 1996 |
Cloning and functional expression of a human liver organic cation transporter.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Liver; Membrane Proteins; Molecular Sequence Data; Oocytes; Organic Cation Transporter 1; Polymerase Chain Reaction; Rats; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Tissue Distribution; Xenopus laevis | 1997 |
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection | 1998 |
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis | 1999 |
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
Topics: Animals; Anions; Carrier Proteins; Cations; Cell Line; Cell Membrane; Choline; Cloning, Molecular; Female; Guanidine; Histamine; Humans; In Vitro Techniques; Kidney; Kinetics; Membrane Potentials; Membrane Proteins; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Transfection; Xenopus laevis | 2001 |
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antimalarials; Biological Transport, Active; Digoxin; Enzyme Inhibitors; Estradiol; Ibuprofen; LLC-PK1 Cells; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Quinidine; Quinine; Rats; Rifampin; Swine | 2002 |
Synthesis and evaluation of new antimalarial analogues of quinoline alkaloids derived from Cinchona ledgeriana Moens ex Trimen.
Topics: Animals; Antimalarials; Chloroquine; Cinchona Alkaloids; Drug Design; Drug Resistance; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Plasmodium; Quinolines; Structure-Activity Relationship | 2002 |
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
Topics: Adenosine Triphosphatases; Algorithms; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Caco-2 Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Radioligand Assay; Rhodamine 123; Stereoisomerism; Verapamil; Vinblastine | 2002 |
Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Coumarins; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Ligands; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Protein Binding; Quinidine; Quinine; Rabbits; Rats; Sequence Homology, Amino Acid; Sparteine; Species Specificity | 2003 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry.
Topics: Animals; Apamin; Guinea Pigs; Hepatocytes; Kinetics; Molecular Conformation; Potassium Channels, Calcium-Activated | 2004 |
Interaction of organic cations with a newly identified plasma membrane monoamine transporter.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cell Line; Dogs; Equilibrative Nucleoside Transport Proteins; Humans; Membrane Transport Proteins; Nerve Tissue Proteins; Organic Cation Transport Proteins; Tyramine | 2005 |
A clinical drug library screen identifies astemizole as an antimalarial agent.
Topics: Animals; Antimalarials; Astemizole; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Drug Resistance, Multiple; Humans; Mice; Plasmodium falciparum; Plasmodium yoelii | 2006 |
New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation.
Topics: Animals; Antioxidants; Cell Line, Tumor; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Mice; PrPSc Proteins; Pyrazolones; Structure-Activity Relationship; Superoxide Dismutase | 2007 |
Pharmacophore based discovery of potential antimalarial agent targeting haem detoxification pathway.
Topics: Animals; Antimalarials; Drug Discovery; Heme; Isoniazid; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Stereoisomerism | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum.
Topics: Antimalarials; Chloroquine; Cinchona Alkaloids; Drug Resistance; Inhibitory Concentration 50; Molecular Structure; Plasmodium falciparum; Quinine | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Antiparasitic hybrids of Cinchona alkaloids and bile acids.
Topics: Antiparasitic Agents; Bile Acids and Salts; Cell Line; Cinchona Alkaloids; Humans; Inhibitory Concentration 50 | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Structure-activity relationship of hybrids of Cinchona alkaloids and bile acids with in vitro antiplasmodial and antitrypanosomal activities.
Topics: Antimalarials; Bile Acids and Salts; Cinchona Alkaloids; Dose-Response Relationship, Drug; Molecular Conformation; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2015 |
Effects of antacids on gastrointestinal absorption of drugs.
Topics: Animals; Antacids; Aspirin; Chlordiazepoxide; Chlorpromazine; Dicumarol; Digitoxin; Digoxin; Ephedrine; Guinea Pigs; Humans; Intestinal Absorption; Iron; Isoniazid; Levodopa; Naproxen; Pentobarbital; Pharmaceutical Preparations; Quinidine; Quinine; Rats; Sulfadiazine; Tetracyclines; Warfarin | 1976 |
Chloroquine, quinine, procaine, quinidine, tricyclic antidepressants, and methylxanthines as prostaglandin agonists and antagonists.
Topics: Antidepressive Agents, Tricyclic; Antimalarials; Chloroquine; Ductus Arteriosus, Patent; Humans; Infant; Procaine; Prostaglandin Antagonists; Quinidine; Quinine; Xanthines | 1976 |
Quinine dermatitis: investigation of a factory outbreak.
Topics: Adult; Dermatitis, Occupational; Drug Industry; Humans; Male; Middle Aged; Patch Tests; Quinidine; Quinine; Time Factors | 1978 |
X-ray powder diffraction data for some drugs, excipients, and adulterants in illicit samples.
Topics: Ascorbic Acid; Benzocaine; Carbohydrates; Drug Contamination; Forensic Medicine; Humans; Narcotics; Pharmaceutical Preparations; Powders; Psychotropic Drugs; Quinidine; Quinine; Saccharin; Silicon Dioxide; Starch; X-Ray Diffraction | 1975 |
Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations.
Topics: Adenylyl Cyclases; Antimalarials; Atropine; Chloroquine; Cyclic AMP; Histamine; Kinetics; Neurospora; Neurospora crassa; Phosphoric Diester Hydrolases; Quinidine; Quinine; Theophylline | 1975 |
Potassium permeability activated by intracellular calcium ion concentration in the pancreatic beta-cell.
Topics: Action Potentials; Animals; Azides; Calcium; Cell Membrane Permeability; Dinitrophenols; Electric Conductivity; Glucose; Hydrazones; In Vitro Techniques; Ion Channels; Islets of Langerhans; Membrane Potentials; Mice; Potassium; Quinidine; Quinine | 1979 |
[Direct spectrophotometric measuring of the 2 major alkaloid pairs of the Chinae succirubrae cortex].
Topics: Quinidine; Quinine; Spectrophotometry | 1977 |
Absence of the platelet receptor for drug-dependent antibodies in the Bernard-Soulier syndrome.
Topics: Antibodies; Binding Sites; Blood Platelet Disorders; Blood Platelets; Blood Proteins; Cell Membrane; Chymotrypsin; Glycoproteins; Humans; Membrane Proteins; Quinidine; Quinine; Syndrome; Trypsin | 1978 |
Detection of drug-dependent antibodies by the 51Cr platelet lysis test: documentation of immune thrombocytopenia induced by diphenylhydantoin, diazepam, and sulfisoxazole.
Topics: Adolescent; Antibodies; Antibody Specificity; Blood Platelets; Chromium Radioisotopes; Diazepam; Female; Humans; Male; Middle Aged; Phenytoin; Quinidine; Quinine; Sulfisoxazole; Thrombocytopenia | 1977 |
[Effect of drug therapy during pregnancy on the clotting potential of the newborn].
Topics: Aspirin; Blood Coagulation Disorders; Drug-Related Side Effects and Adverse Reactions; Female; Hemostasis; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Pregnancy; Quinidine; Quinine; Thiazines; Tolbutamide | 1977 |
Comparison of the antiarrhythmic activity of quinidine and quinine.
Topics: Acetylcholine; Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Bundle of His; Cats; Dogs; Electric Stimulation; Female; Heart Ventricles; Male; Neural Conduction; Ouabain; Purkinje Fibers; Quinidine; Quinine; Refractory Period, Electrophysiological; Time Factors; Ventricular Fibrillation | 1977 |
Colorimetric assay of quinine and quinidine in raw materials, formulations, and biological fluids.
Topics: Adult; Chromatography, Thin Layer; Cinchona Alkaloids; Colorimetry; Drug Combinations; Humans; Indicators and Reagents; Male; Quinidine; Quinine; Solutions; Tablets | 1977 |
A potassium contribution to the response of the barnacle photoreceptor.
Topics: Adaptation, Ocular; Animals; Calcium; Electric Conductivity; In Vitro Techniques; Membrane Potentials; Photoreceptor Cells; Potassium; Quinidine; Quinine; Thoracica | 1977 |
Chloroquine, quinine, procaine, quinidine and clomipramine are prostaglandin agonists and antagonists.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Chloroquine; Clomipramine; Dibenzazepines; Indomethacin; Male; Mesenteric Arteries; Norepinephrine; Procaine; Prostaglandin Antagonists; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Quinidine; Quinine; Rats | 1976 |
Inhibition of the calcium-induced increase in the potassium permeability of human red blood cells by quinine.
Topics: Calcium; Cell Membrane Permeability; Erythrocytes; Humans; In Vitro Techniques; Potassium; Quinidine; Quinine | 1975 |
[Chromatography of cinchona alkaloids on thin-layer Silufol].
Topics: Chromatography, Thin Layer; Cinchona; Plants, Medicinal; Quinidine; Quinine | 1975 |
Nonaqueous titration of sulfates of quinine and quinidine using barium acetate.
Topics: Acetates; Barium; Carbonates; Methods; Potentiometry; Quinidine; Quinine; Sulfates; Sulfuric Acids; Tablets | 1976 |
Disposition of quinine in rats with induced renal failure.
Topics: Acute Kidney Injury; Animals; Chromatography, High Pressure Liquid; Gentamicins; Glycerol; Injections, Intraperitoneal; Male; Mercuric Chloride; Quinidine; Quinine; Rats; Rats, Wistar; Urea | 1992 |
Stereoselective inhibition of renal organic cation transport in human kidney.
Topics: Adult; Aged; Amantadine; Animals; Cations; Female; Humans; In Vitro Techniques; Kidney; Kidney Cortex; Male; Middle Aged; Quinidine; Quinine; Rats; Stereoisomerism | 1992 |
Inhibition by basic drugs of digoxin secretion into human bile.
Topics: Bile; Chromatography, High Pressure Liquid; Digoxin; Drug Interactions; Humans; Probenecid; Quinidine; Quinine; Radioimmunoassay; Spironolactone; Verapamil | 1992 |
Quinine or quinidine?
Topics: Canada; Communication; Drug Prescriptions; Humans; Legislation, Pharmacy; Medication Errors; Nurses; Quinidine; Quinine; Telephone | 1992 |
Systemic quinine photosensitivity with photoepicutaneous cross-reactivity to quinidine.
Topics: Aged; Humans; Male; Patch Tests; Photosensitivity Disorders; Quinidine; Quinine; Ultraviolet Rays | 1992 |
Characterization of multiple quinine-dependent antibodies in a patient with episodic hemolytic uremic syndrome and immune agranulocytosis.
Topics: Adult; Antigens, Surface; Autoantibodies; Blood Platelets; Cell Adhesion; Endothelium, Vascular; Erythrocytes; Female; Hemolytic-Uremic Syndrome; Humans; Molecular Weight; Neutropenia; Neutrophils; Periodicity; Platelet Membrane Glycoproteins; Quinidine; Quinine; T-Lymphocytes; Thrombocytopenia | 1992 |
The effect of fever on quinine and quinidine disposition in the rat.
Topics: Animals; Biotransformation; Fever; Liver; Male; Microsomes, Liver; Myocardium; Quinidine; Quinine; Rats; Rats, Inbred Strains | 1991 |
The influence of alpha 1-acid glycoprotein on quinine and quinidine disposition in the rat isolated perfused liver preparation.
Topics: Animals; Half-Life; Liver; Male; Orosomucoid; Oxygen Consumption; Protein Binding; Quinidine; Quinine; Rats; Rats, Inbred Strains | 1991 |
Role of quinidine in the mexiletine-quinidine interaction: electrophysiologic correlates of enhanced antiarrhythmic efficacy.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Diazepam; Dogs; Drug Combinations; Drug Interactions; Heart Conduction System; Mexiletine; Quinidine; Quinine; Refractory Period, Electrophysiological | 1990 |
Quinidine/quinine: stereospecific electrophysiologic and antiarrhythmic effects in a canine model of ventricular tachycardia.
Topics: Animals; Dogs; Heart Conduction System; Quinidine; Quinine; Refractory Period, Electrophysiological; Tachycardia | 1990 |
Characteristics of quinine- and quinidine-induced antibodies specific for platelet glycoproteins IIb and IIIa.
Topics: Animals; Autoantibodies; Chymotrypsin; Epitopes; Humans; Immunoblotting; Immunoglobulin G; Immunosorbent Techniques; Mice; Peptide Fragments; Platelet Membrane Glycoproteins; Quinidine; Quinine; Thrombocytopenia | 1991 |
Quinine and quinidine.
Topics: Cardiology; History, 17th Century; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Plants, Medicinal; Quinidine; Quinine | 1991 |
Quinidine but not quinine inhibits in man the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase.
Topics: Adult; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Humans; Male; Methamphetamine; Mixed Function Oxygenases; Oxidation-Reduction; Quinidine; Quinine | 1991 |
Quinine is a more potent inhibitor than quinidine in rat of the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase.
Topics: Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Methamphetamine; Mixed Function Oxygenases; Oxidation-Reduction; Quinidine; Quinine; Rats; Rats, Inbred Lew | 1991 |
High-performance liquid chromatographic method for the quantitation of quinidine and selected quinidine metabolites.
Topics: Chromatography, High Pressure Liquid; Cyclic N-Oxides; Humans; Quinidine; Quinine; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1991 |
Interactions of quinidine and quinine and (+)- and (-)-pindolol with the organic cation/proton antiporter in renal brush border membrane vesicles.
Topics: Animals; Biological Transport; Carrier Proteins; Hydrogen-Ion Concentration; Kidney Cortex; Kinetics; Microvilli; Niacinamide; Pindolol; Quinidine; Quinine; Rabbits; Stereoisomerism | 1991 |
Comparative evaluation of blood schizontocidal activity of quinine and quinidine against drug resistant rodent malaria.
Topics: Animals; Drug Evaluation, Preclinical; Drug Resistance; Malaria; Mice; Plasmodium berghei; Plasmodium yoelii; Quinidine; Quinine | 1991 |
Treatment of severe Plasmodium falciparum malaria with quinidine gluconate: discontinuation of parenteral quinine from CDC drug service.
Topics: Animals; Antimalarials; Centers for Disease Control and Prevention, U.S.; Humans; Infusions, Intravenous; Malaria; Plasmodium falciparum; Quinidine; Quinine; United States | 1991 |
Oxidation of reduced haloperidol to haloperidol: involvement of human P450IID6 (sparteine/debrisoquine monooxygenase).
Topics: Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Haloperidol; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Quinidine; Quinine | 1991 |
Bioconversion of quininone to quinidine by resting cells of Hansenula anomala var. schneggii.
Topics: Biotransformation; Pichia; Quinidine; Quinine | 1991 |
Disposition of the diastereoisomers quinine and quinidine in the ovine fetus.
Topics: Animals; Chromatography, High Pressure Liquid; Creatinine; Female; Fetus; Placenta; Pregnancy; Quinidine; Quinine; Sheep; Stereoisomerism | 1991 |
Characterization of the principal metabolite of quinine in human urine by 1H-n.m.r. spectroscopy.
Topics: Adult; Humans; Magnetic Resonance Spectroscopy; Male; Quinidine; Quinine | 1991 |
Quinine and quinidine cross-react after systemic photosensitization in the mouse.
Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Interactions; Female; Injections, Intraperitoneal; Mice; Photosensitivity Disorders; Quinidine; Quinine; Ultraviolet Rays | 1990 |
The effect of malaria infection on the disposition of quinine and quinidine in the rat isolated perfused liver preparation.
Topics: Animals; Chromatography, Liquid; In Vitro Techniques; Liver; Malaria; Male; Perfusion; Plasmodium berghei; Quinidine; Quinine; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1990 |
Quinine or quinidine?
Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Female; Humans; Medication Errors; Quinidine; Quinine | 1991 |
Quinidine--an alternative to quinine for malaria.
Topics: Animals; Humans; Malaria; Plasmodium falciparum; Quinidine; Quinine | 1991 |
High-performance liquid chromatographic-mass spectrometric assay of high-value compounds for pharmaceutical use from plant cell tissue culture: Cinchona alkaloids.
Topics: Chromatography, High Pressure Liquid; Cinchona Alkaloids; Culture Techniques; Mass Spectrometry; Quinidine; Quinine; Spectrometry, Mass, Fast Atom Bombardment | 1991 |
Comparative effects of the diastereoisomers, quinine and quinidine in producing phenocopy debrisoquine poor metabolisers (PMs) in healthy volunteers.
Topics: Adult; Debrisoquin; Desipramine; Female; Humans; Male; Metabolic Clearance Rate; Molecular Structure; Nortriptyline; Phenotype; Quinidine; Quinine; Reference Values; Stereoisomerism | 1991 |
Altered flecainide disposition in healthy volunteers taking quinine.
Topics: Adult; Biotransformation; Cimetidine; Drug Interactions; Electrocardiography; Flecainide; Half-Life; Heart Rate; Humans; Male; Quinidine; Quinine; Reference Values | 1990 |
A comparison of the antimalarial activity of the cinchona alkaloids against Plasmodium falciparum in vitro.
Topics: Animals; Chromatography, High Pressure Liquid; Cinchona Alkaloids; Drug Combinations; Isomerism; Plasmodium falciparum; Quinidine; Quinine | 1990 |
The in vitro response of Plasmodium falciparum to amodiaquine, quinine and quinidine in Tanga region, Tanzania.
Topics: Adolescent; Amodiaquine; Animals; Child; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Quinidine; Quinine; Tanzania | 1990 |
Potential usefulness of quinine to circumvent the anthracycline resistance in clinical practice.
Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Colonic Neoplasms; Drug Resistance; Drug Synergism; Epirubicin; In Vitro Techniques; Quinidine; Quinine; Rats; Verapamil | 1990 |
Stereoselective inhibition of amantadine accumulation by quinine and quinidine in rat renal proximal tubules and cortical slices.
Topics: Amantadine; Animals; Biological Transport; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Proximal; Quinidine; Quinine; Rats; Stereoisomerism | 1990 |
Detection of drug-dependent, platelet-reactive antibodies by antigen-capture ELISA and flow cytometry.
Topics: Antibodies; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Humans; Quinidine; Quinine; Thrombocytopenia | 1990 |
Comparative effects of quinine and quinidine on glucose metabolism in healthy volunteers.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Glucose; Humans; Infusion Pumps; Insulin; Islets of Langerhans; Male; Quinidine; Quinine | 1990 |
Activity of various amphiphilic agents in reversing multidrug resistance of L 1210 cells.
Topics: Animals; Drug Resistance; Ethylamines; Hycanthone; Leukemia L1210; Phenotype; Piperidines; Quinidine; Quinine; Tamoxifen; Trifluoperazine; Verapamil | 1990 |
A maxi calcium-activated potassium channel from chick lens epithelium.
Topics: Animals; Barium; Calcium; Cell Membrane Permeability; Cesium; Chick Embryo; Chickens; Decamethonium Compounds; Epithelium; Lens, Crystalline; Membrane Potentials; Potassium Channels; Quinidine; Quinine; Sodium; Tetraethylammonium Compounds | 1990 |
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil | 1990 |
The adsorption of quinine and quinidine to activated charcoal with and without magnesium sulfate.
Topics: Adsorption; Antidotes; Charcoal; Humans; Magnesium Sulfate; Poisoning; Quinidine; Quinine | 1990 |
[Discovery of the cardiac effectiveness of cinchona bark and its alkaloids].
Topics: Arrhythmias, Cardiac; Cinchona Alkaloids; Europe; Heart; History, 17th Century; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Quinidine; Quinine | 1990 |
Simultaneous measurement of quinine and quinidine in human plasma, whole blood, and erythrocytes by high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Erythrocytes; Fluorescence; Humans; Quinidine; Quinine; Time Factors | 1990 |
Interactions in the renal and biliary elimination of digoxin: stereoselective difference between quinine and quinidine.
Topics: Adult; Bile; Digoxin; Duodenum; Humans; Kidney Tubules; Liver; Male; Perfusion; Quinidine; Quinine; Stereoisomerism | 1990 |
Quinidine oxidative metabolism. Identification and biosynthesis of quinidine 10,11-dihydrodiol stereoisomers.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Molecular Structure; Phenobarbital; Quinidine; Quinine; Rats; Rats, Inbred Strains; Stereoisomerism | 1990 |
Effect of oral activated charcoal on the pharmacokinetics of quinidine and quinine administered intravenously to rabbits.
Topics: Animals; Charcoal; Half-Life; Injections, Intravenous; Male; Quinidine; Quinine; Rabbits | 1990 |
[Myotonic syndrome].
Topics: Animals; Electromyography; Humans; Membrane Potentials; Myotonia; Quinidine; Quinine | 1990 |
Autoregulation of apical membrane Na+ permeability of tight epithelia. Noise analysis with amiloride and CGS 4270.
Topics: Amiloride; Animals; Cell Membrane Permeability; Electricity; Epithelium; Homeostasis; Ion Channels; Physiology; Pyrazines; Quinidine; Quinine; Rana pipiens; Skin; Sodium | 1985 |
Inhibition of Ca2+-activated K+ channels in pig pancreatic acinar cells by Ba2+, Ca2+, quinine and quinidine.
Topics: Animals; Barium; Calcium; Electrophysiology; In Vitro Techniques; Ion Channels; Pancreas; Potassium; Quinidine; Quinine; Swine | 1985 |
Adenosine 5'-triphosphate modulates membrane potassium conductance in guinea-pig myenteric neurones.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; Intestine, Small; Membrane Potentials; Neurons; Potassium; Quinidine; Quinine; Substance P; Tetraethylammonium Compounds; Tetrodotoxin | 1989 |
Comparative multiple dose pharmacokinetics of quinine, quinidine and quinidine sustained release.
Topics: Adult; Delayed-Action Preparations; Humans; Male; Quinidine; Quinine | 1989 |
Comparison of disposition parameters of quinidine and quinine in the rat.
Topics: Animals; Bile; Blood Proteins; Injections, Intravenous; Male; Metabolic Clearance Rate; Protein Binding; Quinidine; Quinine; Rats; Rats, Inbred Strains; Stereoisomerism; Tissue Distribution | 1989 |
Quinidine and quinine effects on the slow wave activity of colonic circular muscle.
Topics: Animals; Colon; Dogs; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Quinidine; Quinine | 1989 |
Determination of quinine and quinidine in biological fluids by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Quinidine; Quinine | 1989 |
The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man.
Topics: Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Debrisoquin; Humans; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; Quinidine; Quinine; Rats; Rats, Inbred Strains; Species Specificity | 1989 |
Differing susceptibilities of platelets from normal individuals and patients with von Willebrand's disease to attack by quinine- and quinidine-dependent antiplatelet antibodies.
Topics: Autoantibodies; Blood Platelets; HLA Antigens; Humans; Immunoblotting; Immunoglobulin G; Platelet Aggregation; Platelet Factor 3; Quinidine; Quinine; Serotonin; von Willebrand Diseases; von Willebrand Factor | 1989 |
Membrane potential measurements of transitional cells from the crista ampullaris of the gerbil. Effects of barium, quinidine, quinine, tetraethylammonium, cesium, ammonium, thallium and ouabain.
Topics: Animals; Cations; Chlorides; Ear, Inner; Electrophysiology; Gerbillinae; In Vitro Techniques; Membrane Potentials; Ouabain; Quinidine; Quinine; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand.
Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Chloroquine; Female; Follow-Up Studies; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Quinidine; Quinine; Quinolines; Recurrence; Thailand | 1987 |
Heterogeneity of drug-dependent platelet antigens and their antibodies in quinine- and quinidine-induced thrombocytopenia: involvement of glycoproteins Ib, IIb, IIIa, and IX.
Topics: Antigens, Differentiation; Binding Sites, Antibody; Blood Platelet Disorders; Blood Platelets; Blotting, Western; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Isoantibodies; Isoantigens; Platelet Membrane Glycoproteins; Quinidine; Quinine; Receptors, Fc; Receptors, IgG; Thrombocytopenia | 1988 |
In vivo and in vitro responses to quinine and quinidine of Plasmodium falciparum.
Topics: Animals; Child; Child, Preschool; Female; Humans; Malaria; Male; Plasmodium falciparum; Prospective Studies; Quinidine; Quinine; Random Allocation | 1988 |
Phototoxic properties of quinine and quinidine: two quinoline methanol isomers.
Topics: Animals; Candida albicans; Dose-Response Relationship, Drug; Female; Hemolysis; Injections, Intraperitoneal; Mice; Quinidine; Quinine; Tail; Ultraviolet Rays | 1988 |
Serial studies on the evolution of drug resistance in malaria in an area of east Africa: findings from 1979 up to 1986.
Topics: Age Factors; Amodiaquine; Animals; Antibodies, Protozoan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Quinolines; Sulfadoxine; Tanzania | 1988 |
Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes.
Topics: Cytochrome P-450 Enzyme System; Dealkylation; Debrisoquin; Humans; Hydroxylation; In Vitro Techniques; Isoquinolines; Kinetics; Metoprolol; Microsomes, Liver; Quinidine; Quinine; Sparteine | 1988 |
Single-dose comparative kinetics and bioavailability study of quinine hydrochloride, quinidine sulfate and quinidine bisulfate sustained-release in healthy male volunteers.
Topics: Adult; Biological Availability; Delayed-Action Preparations; Humans; Malaria; Male; Quinidine; Quinine | 1988 |
Activity of a combination of three cinchona bark alkaloids against Plasmodium falciparum in vitro.
Topics: Animals; Cinchona Alkaloids; Drug Resistance; Drug Synergism; Humans; Plasmodium falciparum; Quinidine; Quinine | 1988 |
Treatment of chloroquine-resistant falciparum malaria with a combination of quinine, quinidine and cinchonine (LA40221) in adults by oral and intravenous administration.
Topics: Administration, Oral; Adult; Animals; Antimalarials; Cinchona Alkaloids; Drug Combinations; Humans; Infusions, Intravenous; Malaria; Male; Plasmodium falciparum; Quinidine; Quinine | 1987 |
Gametocytocidal effect in vitro of cinchona alkaloids and derivatives on a Plasmodium falciparum clone.
Topics: Animals; Chemical Phenomena; Chemistry; Cinchona Alkaloids; Plasmodium falciparum; Quinidine; Quinine | 1987 |
Compared response to chloroquine, fansidar, quinine, and quinidine slow release of infections with Plasmodium falciparum in the Kivu region of Zaire.
Topics: Animals; Antimalarials; Chloroquine; Delayed-Action Preparations; Democratic Republic of the Congo; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Sulfadoxine; Sulfanilamides | 1987 |
Improved resolution of enantiomers of naproxen by the simultaneous use of a chiral stationary phase and a chiral additive in the mobile phase.
Topics: Chromatography, Liquid; Naproxen; Quinidine; Quinine; Stereoisomerism | 1988 |
Inhibition of desipramine 2-hydroxylation by quinidine and quinine.
Topics: Adult; Desipramine; Drug Interactions; Female; Humans; Hydroxylation; Male; Quinidine; Quinine | 1988 |
Antibody-mediated platelet destruction by quinine, quinidine, and their metabolites.
Topics: Antibody Formation; Antibody-Dependent Cell Cytotoxicity; Blood Platelets; Chemical Phenomena; Chemistry; Complement System Proteins; Humans; Quinidine; Quinine; Thrombocytopenia | 1988 |
Proceedings of the symposium on the use of quinine and quinidine in malaria. Amsterdam, 9-11 March 1987.
Topics: Humans; Malaria; Quinidine; Quinine | 1987 |
Differences in the binding of quinine and quinidine to plasma proteins.
Topics: Adult; Blood Proteins; Dialysis; Female; Fetal Blood; Humans; Male; Orosomucoid; Protein Binding; Quinidine; Quinine; Serum Albumin | 1987 |
Quinidine and the identification of drugs whose elimination is impaired in subjects classified as poor metabolizers of debrisoquine.
Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Humans; In Vitro Techniques; Isoenzymes; Isoquinolines; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenotype; Quinidine; Quinine | 1986 |
[In vitro and in vivo photochemical reactivity of quinine- and quinidine-N-oxide].
Topics: Animals; Cyclic N-Oxides; In Vitro Techniques; Mass Spectrometry; Photochemistry; Quinidine; Quinine; Rats; Rats, Inbred Strains; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1986 |
High-performance liquid chromatographic analysis of quinine and its diastereoisomer quinidine.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Fetal Blood; Indicators and Reagents; Kinetics; Pregnancy; Quinidine; Quinine; Sheep; Stereoisomerism | 1987 |
Polarisation fluoroimmunoassay for quinine in serum and urine.
Topics: Adult; Antimalarials; Cross Reactions; Fluorescence Polarization; Humans; Kinetics; Male; Quinidine; Quinine | 1987 |
Quinine- and quinidine platelet antibodies can react with GPIIb/IIIa.
Topics: Antigen-Antibody Reactions; Bernard-Soulier Syndrome; Blood Platelets; Humans; Platelet Membrane Glycoproteins; Precipitin Tests; Quinidine; Quinine; Rosette Formation | 1987 |
Effects of quinidine and quinine on the excitability of pyramidal neurons in guinea-pig hippocampal slices.
Topics: Animals; Electric Stimulation; Guinea Pigs; Hippocampus; Membrane Potentials; Nerve Fibers; Neurons; Quinidine; Quinine | 1986 |
Stereoselective renal tubular secretion of quinidine and quinine.
Topics: Adult; Aged; Biological Transport; Humans; Hydrogen-Ion Concentration; Kidney Tubules; Kinetics; Male; Middle Aged; Protein Binding; Quinidine; Quinine; Stereoisomerism; Urine | 1986 |
Transport of cimetidine by the rat choroid plexus in vitro.
Topics: Amino Acids; Animals; Biological Transport, Active; Choroid Plexus; Cimetidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Male; Mathematics; Oligopeptides; Penicillin G; Proline; Quinidine; Quinine; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1986 |
Binding of quinine- and quinidine-dependent drug antibodies to platelets is mediated by the Fab domain of the immunoglobulin G and is not Fc dependent.
Topics: Autoantibodies; Binding, Competitive; Blood Platelets; Cell Membrane; Complement Fixation Tests; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Quinidine; Quinine; Radioimmunoassay; Thrombocytopenia | 1987 |
Fab-mediated binding of drug-dependent antibodies to platelets in quinidine- and quinine-induced thrombocytopenia.
Topics: Antibodies; Antibodies, Anti-Idiotypic; Blood Platelets; Depression, Chemical; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Protein Binding; Quinidine; Quinine; Receptors, Antigen, B-Cell; Rosette Formation; Staphylococcal Protein A; Thrombocytopenia | 1985 |
Molecular characterization of quinine/quinidine drug-dependent antibody platelet interaction using monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Binding Sites, Antibody; Blood Platelets; Fluorescent Antibody Technique; Glycoproteins; Humans; Peptide Hydrolases; Platelet Aggregation; Quinidine; Quinine | 1985 |
The treatment of severe falciparum malaria.
Topics: Exchange Transfusion, Whole Blood; Humans; Malaria; Plasmodium falciparum; Quinidine; Quinine | 1985 |
Effect of quinine on mitochondrial K+ and Mg++ flux.
Topics: Animals; Biological Transport; Magnesium; Mitochondria, Liver; Permeability; Potassium; Quinidine; Quinine; Quinuclidines; Rats; Uncoupling Agents | 1986 |
Specific immunoassays for quinine and quinidine: comparison of radioimmunoassay and enzyme-linked immunosorbent assay procedures.
Topics: Cross Reactions; Enzyme-Linked Immunosorbent Assay; Quinidine; Quinine; Radioimmunoassay | 1985 |
Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH.
Topics: Chloroquine; Coumarins; Heterocyclic Compounds; Hydralazine; Indophenol; NADP; Novobiocin; Quinacrine; Quinidine; Quinine; Quinolines; Spectrophotometry; Warfarin | 1974 |
Effects of quinidine on some reactions and ion translocations catalyzed by the Na+, K+ -ATPase complex.
Topics: Adenosine Triphosphatases; Animals; Brain; Cardiac Glycosides; Cattle; Dose-Response Relationship, Drug; Erythrocytes; Heart; Humans; In Vitro Techniques; Myocardium; Ouabain; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Potassium; Quinidine; Quinine; Rats; Rubidium; Sodium | 1973 |
[Influence on curare-like action of drugs used in therapy].
Topics: Anti-Bacterial Agents; Barbiturates; Cholinesterase Inhibitors; Ganglionic Blockers; Humans; Magnesium; Muscles; Pituitary Hormones, Anterior; Procaine; Quinidine; Quinine; Vitamins | 1964 |
Actions of emetine dehydroemetine, quinine and quinidine on Finkleman preparation of rabbit ileum.
Topics: Adrenergic beta-Antagonists; Animals; Culture Techniques; Emetine; Ileum; Neurons; Quinidine; Quinine; Rabbits | 1972 |
The separation and evaluation of alkaloids of cinchona by thin-layer chromatography and gas liquid chromatography.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Cinchona; Plants, Medicinal; Quinidine; Quinine; Quinuclidines | 1974 |
[Trial of a new cerebral vasoregulator: viquidil hydrochloride, in black Africans].
Topics: Adult; Age Factors; Aged; Black People; Cerebrovascular Disorders; Female; Humans; Intracranial Arteriosclerosis; Isomerism; Male; Middle Aged; Quinidine; Quinine; Time Factors | 1974 |
[UV-spectrophotometry in drug control. 14. Characterization and determination of drugs with quinoline and isoquinoline chromophores].
Topics: Amodiaquine; Chloroquine; Hydroxychloroquine; Isoquinolines; Papaverine; Primaquine; Quinidine; Quinine; Quinolines; Spectrophotometry, Ultraviolet | 1974 |
Antimalarial activity of racemic 3-epidihydroquinine, 3-epidihydroquinidine and their various racemic analogs in mice infected with Plasmodium berghei.
Topics: Animals; Chemical Phenomena; Chemistry; Malaria; Mice; Plasmodium berghei; Quinidine; Quinine; Structure-Activity Relationship | 1973 |
[Quinidine (or quinine) determination in biological media].
Topics: Animals; Benzene; Body Fluids; Chromatography, Thin Layer; Dogs; Methods; Quinidine; Quinine; Solvents; Spectrometry, Fluorescence | 1972 |
[Chromatographic separation of the main alkaloids found in Chinae succirubrae cortex (Ph. Hg. VI.)].
Topics: Chromatography, Paper; Cinchona; Plants, Medicinal; Quinidine; Quinine | 1973 |
Examination of quinidine and quinine and their pharmaceutical preparations.
Topics: Alkaloids; Capsules; Chemistry, Pharmaceutical; Chromatography, Gas; Chromatography, Thin Layer; Cinchona; Crystallization; Plants, Medicinal; Powders; Quinidine; Quinine; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfates; Tablets | 1973 |
[Rapid analysis of the main alkaloid ratio in extracts of cortex Chinae succirubrae (Ph.Hung.VI)].
Topics: Chromatography, Paper; Cinchona; Densitometry; Methods; Plant Extracts; Plants, Medicinal; Quinidine; Quinine; Spectrophotometry, Ultraviolet | 1973 |
Drug fever caused by quinine and quinidine.
Topics: Adult; Drug Hypersensitivity; Fever; Humans; Male; Middle Aged; Quinidine; Quinine | 1973 |
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro.
Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts | 1973 |
Some effects of quinidine and quinine on the electromyogram of the colon.
Topics: Action Potentials; Animals; Cats; Colon; Electrodes; Electromyography; In Vitro Techniques; Quinidine; Quinine | 1973 |
Fluorescence of 6-methoxyquinoline, quinine, and quinidine in aqueous media.
Topics: Chemical Phenomena; Chemistry; Fluorescence; Hydrogen-Ion Concentration; Quinidine; Quinine; Quinolines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
[Immune thrombocytopenia].
Topics: Acetazolamide; Anemia, Hemolytic, Autoimmune; Autoantibodies; Autoimmune Diseases; Blood Coagulation Tests; Chlorothiazide; Complement Fixation Tests; Drug Hypersensitivity; Fluorescent Antibody Technique; Humans; Hypnotics and Sedatives; Isoantibodies; Lupus Erythematosus, Systemic; Prednisone; Quinidine; Quinine; Splenectomy; Sulfonamides; Thrombocytopenia; Virus Diseases | 1970 |
Synthesis of 9-epi-quinine and 9-epi-quinidine.
Topics: Magnetic Resonance Spectroscopy; Mass Spectrometry; Methods; Quinidine; Quinine | 1972 |
[Misleading indications on the EKG due to pharmacologic influences].
Topics: Antidepressive Agents; Cardiac Glycosides; Diagnosis; Diagnostic Errors; Electrocardiography; Humans; Potassium Deficiency; Quinidine; Quinine; Vasodilator Agents | 1972 |
Thrombocytopenia. II. Drug-induced thrombocytopenia.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Platelet Disorders; Child; Child, Preschool; Diuretics; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Purpura, Thrombocytopenic; Quinidine; Quinine; Remission, Spontaneous; Sex Factors | 1972 |
Hydrochlorothiazide-dependent thrombocytopenia due to IgM antibody.
Topics: Aged; Blood Cell Count; Blood Platelets; Complement Fixation Tests; Humans; Hydrochlorothiazide; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulin M; Macroglobulins; Male; Purpura, Thrombocytopenic; Quinidine; Quinine | 1971 |
Antimalarial activity of natural, racemic and unnatural dihydroquinine, dihydroquinidine and their various racemic analogs in mice infected with Plasmodium berghei.
Topics: Administration, Oral; Animals; Antimalarials; Injections, Intraperitoneal; Lethal Dose 50; Malaria; Male; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Plasmodium; Quinidine; Quinine; Stereoisomerism | 1971 |
[On the circular dichroism of quinoalkaloids].
Topics: Chemical Phenomena; Chemistry; Color; Quinidine; Quinine | 1966 |
[Layer chromatographic separation and purification of Cinchona alkaloids].
Topics: Alkaloids; Chromatography, Thin Layer; Cinchona; Germany; Pharmacopoeias as Topic; Plants, Medicinal; Quinidine; Quinine | 1970 |
[Drug-induced anemias].
Topics: Adrenal Cortex Hormones; Anemia; Barbiturates; Bone Marrow; Chloramphenicol; Chlorpromazine; Dihydroxyphenylalanine; Gastrointestinal Hemorrhage; Gold; Humans; Hypoglycemic Agents; Indomethacin; Isoniazid; Nitrofurantoin; Phenacetin; Phenylbutazone; Phenytoin; Quinidine; Quinine; Salicylates; Sulfonamides | 1970 |
Studies with ion-exchange resins on cinchona alkaloids. 3. Exchange rates.
Topics: Cinchona; Ion Exchange Resins; Plants, Medicinal; Quinidine; Quinine | 1969 |
Quinidine excretion in aciduria and alkaluria.
Topics: Humans; Hydrogen-Ion Concentration; Quinidine; Quinine | 1969 |
Inhibition of lipolytic processes in rat adipose tissue by antimalaria drugs.
Topics: Adipose Tissue; Animals; Antimalarials; Chloroquine; Epididymis; Fatty Acids; Heparin; Hydroxychloroquine; Lipid Metabolism; Male; Primaquine; Quinacrine; Quinidine; Quinine; Rats | 1969 |
Total synthesis of quinine and quinidine. I.
Topics: Quinidine; Quinine | 1970 |
Total synthesis of quinine and quinidine. II.
Topics: Quinidine; Quinine | 1970 |
Two patients with intoxication by cinchona alkaloids.
Topics: Adult; Female; Humans; Male; Middle Aged; Quinidine; Quinine | 1970 |
Quinine--effect on Tetrahymena pyriformis. II. Comparative activity of the stereoisomers, quinidine and quinine.
Topics: Amino Acids; Carbon Isotopes; Cell Division; DNA; Lipids; Protein Biosynthesis; Quinidine; Quinine; RNA; Stereoisomerism; Tetrahymena; Thymidine | 1970 |
[Determination of quinine, quinidine, cinchonine, cinchonidine and sparteine by means of Reinecke's salt].
Topics: Chemistry Techniques, Analytical; Cinchona; Indicators and Reagents; Methods; Plants, Medicinal; Quinidine; Quinine; Salts; Sparteine | 1970 |
Kinetics of calcium transport by fragmented sarcoplasmic reticulum.
Topics: Animals; Biological Transport; Calcium; Calcium Isotopes; Chlorpromazine; Endoplasmic Reticulum; Humans; In Vitro Techniques; Kinetics; Muscles; Oxalates; Quinidine; Quinine; Rabbits; Rats | 1970 |
Nitrogen photochemistry. V. A new photochemical reduction of the cinchona alkaloids, quinine, quinidine, cinchonidine, cinchonine.
Topics: Antimalarials; Chemistry, Pharmaceutical; Cinchona; Oxidation-Reduction; Photochemistry; Plants, Medicinal; Quinidine; Quinine | 1970 |
Bedside toxicology.
Topics: Alcohols; Antimony; Arsenic Poisoning; Barbiturates; Bismuth; Bromides; Carbon Monoxide Poisoning; Child; Coloring Agents; Humans; Indicators and Reagents; Iron; Kerosene; Lead Poisoning; Mercury Poisoning; Methods; Parathion; Phenothiazines; Poisoning; Quinidine; Quinine; Salicylates; Strychnine; Sulfanilamides | 1970 |
Quinine and quinidine inhibition of pentobarbital metabolism.
Topics: Animals; Arousal; Blood Proteins; Brain Chemistry; Carbon Isotopes; Goats; Horses; Humans; In Vitro Techniques; Mice; Microsomes, Liver; Pentobarbital; Protein Binding; Quinidine; Quinine; Rats; Sleep; Species Specificity; Swine; Time Factors | 1970 |
Influence of some antiarrhythmic agents on electrically induced convulsive seizures in rats.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Chloroquine; Electroshock; Female; Lidocaine; Male; Phenytoin; Procainamide; Procaine; Quinidine; Quinine; Rats; Seizures; Time Factors; Water | 1970 |
Antimalarial and other biological activities of some 2'-alkyl and 2'-aryl derivatives of cinchona alkaloids.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Antimalarials; Bacteria; Chemical Phenomena; Chemistry; Chickens; Cinchona; Mice; Microbial Sensitivity Tests; Models, Structural; Plants, Medicinal; Quinidine; Quinine | 1971 |
[Pharmacology of neuromuscular transmission].
Topics: Acetylcholine; Anesthetics, Local; Calcium; Decamethonium Compounds; Magnesium; Neostigmine; Neuromuscular Junction; Nicotine; Phosphates; Physostigmine; Potassium; Quinidine; Quinine; Succinylcholine; Toxins, Biological; Veratrine | 1971 |
[Treatment of arrhythmias].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Diet, Sodium-Restricted; Humans; Hypnotics and Sedatives; Potassium Chloride; Procainamide; Quinidine; Quinine; Rheumatic Fever | 1967 |
Ion-exchange resins and cinchona alkaloids. I. Exchange equilibria.
Topics: Chemical Phenomena; Chemistry; Ion Exchange Resins; Quinidine; Quinine; Quinolines; Sulfates; Sulfonic Acids | 1968 |
A new photoreduction on quinoline alkaloids.
Topics: Alkaloids; Antimalarials; Chemical Phenomena; Chemistry; Oxidation-Reduction; Quinidine; Quinine; Quinolines; Radiation Effects | 1969 |
The metabolic fate of orally administered quinidine gluconate in humans.
Topics: Chemical Phenomena; Chemistry; Chromatography; Chromatography, Gas; Gluconates; Glucuronates; Humans; Methods; Quinidine; Quinine; Quinuclidines; Spectrophotometry; Spectrum Analysis; Ultraviolet Rays | 1969 |
Gas chromatography of alkaloids with polar stationary liquids.
Topics: Alkaloids; Atropine; Chromatography, Gas; Cinchona; Cocaine; Codeine; Morphine; Papaverine; Pilocarpine; Plants, Medicinal; Quinidine; Quinine; Scopolamine; Strychnine; Thebaine | 1965 |
Identification of complexes of phenobarbital with quinine, quinidine, or hydroquinidine in pharmaceutical dosage forms.
Topics: Chemistry, Pharmaceutical; Dosage Forms; Phenobarbital; Quinidine; Quinine; Spectrum Analysis | 1965 |
alpha-Adrenergic blocking properties of quinine HCl.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Blood Pressure; Calcium; Cardiovascular System; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Myocardial Contraction; Norepinephrine; Quinidine; Quinine; Rabbits; Vascular Diseases; Vasoconstrictor Agents | 1980 |
Comparative uptake of quinine and quinidine in rat lung.
Topics: Animals; Kinetics; Lung; Male; Quinidine; Quinine; Rats; Stereoisomerism | 1981 |
Quinidine in falciparum malaria.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cardiovascular System; Drug Tolerance; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Quinidine; Quinine; Thailand | 1981 |
Competitive inhibition of sparteine oxidation in human liver by beta-adrenoceptor antagonists and other cardiovascular drugs.
Topics: Adrenergic beta-Agonists; Cardiovascular Agents; Humans; Kinetics; Liver; Oxidation-Reduction; Quinidine; Quinine; Sparteine | 1984 |
Drug-induced blood disorders.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Hemolytic; Child; Female; Hematologic Diseases; Humans; Male; Middle Aged; Pancytopenia; Quinidine; Quinine; Sulfasalazine; Thrombocytopenia | 1984 |
Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia.
Topics: Antibody Formation; Antigens; Binding Sites, Antibody; Blood Platelet Disorders; Blood Platelets; Cross Reactions; Dose-Response Relationship, Immunologic; Factor VIII; Humans; Quinidine; Quinine; Receptors, Drug; Receptors, IgG; Receptors, Immunologic; Thrombocytopenia; von Willebrand Factor | 1982 |
Potassium current suppression by quinidine reveals additional calcium currents in neuroblastoma cells.
Topics: Action Potentials; Animals; Calcium; Cell Line; Ion Channels; Mice; Neuroblastoma; Potassium; Quinidine; Quinine | 1981 |
Calcium channel and calcium pump involved in oscillatory hyperpolarizing responses of L-strain mouse fibroblasts.
Topics: Animals; Biological Transport, Active; Calcium; Dose-Response Relationship, Drug; Flavonoids; Ion Channels; L Cells; Membrane Potentials; Mice; Nifedipine; Potassium; Quinidine; Quinine | 1982 |
The human platelet receptor(s) for quinine/quinidine-dependent antibodies.
Topics: Antibodies; Antigens; Blood Platelets; Cell Membrane; Factor VIII; Glycoproteins; Humans; Immune Complex Diseases; Membrane Proteins; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Quinidine; Quinine; Receptors, Cell Surface; Receptors, Immunologic; Thrombocytopenia; von Willebrand Factor | 1983 |
Interaction of antimalarial drugs with hemin.
Topics: Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Circular Dichroism; Heme; Hemin; Plasmodium berghei; Quinidine; Quinine; Spectrometry, Fluorescence; Spectrum Analysis | 1983 |
The treatment of falciparum malaria.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinidine; Quinine; Quinolines; Sesquiterpenes | 1984 |
A modified C1q deviation radioimmunoassay for use in a routine clinical laboratory.
Topics: Antigen-Antibody Complex; Binding Sites; Complement C1; Drug Hypersensitivity; Humans; Immune Complex Diseases; Immunoglobulin G; Penicillins; Quinidine; Quinine; Radioimmunoassay | 1980 |
Contact sensitivity to quinidine sulfate from occupational exposure.
Topics: Adult; Animals; Cross Reactions; Dermatitis, Contact; Dermatitis, Occupational; Female; Guinea Pigs; Humans; Male; Middle Aged; Patch Tests; Quinidine; Quinine | 1981 |
High affinity of quinidine for a stereoselective microsomal binding site as determined by a radioreceptor assay.
Topics: Binding, Competitive; Humans; Microsomes, Liver; Molecular Conformation; Quinidine; Quinine; Radioligand Assay | 1984 |
Structural features of the quinidine and quinine molecules necessary for binding of drug-induced antibodies to human platelets.
Topics: Adult; Aged; Antibodies; Antibody Affinity; Binding Sites, Antibody; Blood Platelets; Chromium Radioisotopes; Cross Reactions; Female; Humans; Immunoelectrophoresis; Male; Middle Aged; Quinidine; Quinine; Stereoisomerism; Structure-Activity Relationship; Thrombocytopenia | 1984 |
Drug distribution and binding to muscle in rat.
Topics: Actins; Animals; Carrier Proteins; Cytosol; Furosemide; Male; Muscles; Myosins; Pharmaceutical Preparations; Phenylbutazone; Quinidine; Quinine; Rats; Rats, Inbred Strains; Subcellular Fractions; Tissue Distribution | 1984 |
Comparative disposition kinetics of two diastereomeric pairs of cinchona alkaloids in the dog.
Topics: Animals; Cinchona Alkaloids; Dogs; Injections, Intravenous; Kinetics; Male; Plasma; Quinidine; Quinine; Stereoisomerism | 1984 |
Pharmacokinetic interaction of single doses of quinine and digoxin in dogs.
Topics: Animals; Digoxin; Dogs; Drug Interactions; Infusions, Parenteral; Kinetics; Quinidine; Quinine | 1984 |
Quinine- and quinidine-dependent antiplatelet antibodies. Requirement of factor VIII-related antigen for platelet damage and for in vitro transformation of lymphocytes from patients with drug-induced thrombocytopenia.
Topics: Autoantibodies; Blood Platelets; Factor VIII; Humans; Lymphocyte Activation; Platelet Aggregation; Quinidine; Quinine; Serotonin; Thrombocytopenia | 1981 |
Drugs that increase the serum concentration of digoxin.
Topics: Anti-Bacterial Agents; Calcium Channel Blockers; Digoxin; Drug Interactions; Humans; Quinidine; Quinine; Spironolactone | 1983 |
Feasibility of testing DNA repair inhibitors for mutagenicity by a simple method.
Topics: Depression, Chemical; DNA; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Evaluation, Preclinical; Escherichia coli; Genetic Techniques; Quinacrine; Quinidine; Quinine; Ultraviolet Rays | 1980 |
Study of the factors that cause specific transformation in cultures of lymphocytes from patients with quinine- and quinidine-induced immune thrombocytopenia.
Topics: Antigen-Antibody Complex; Antigens; Blood Platelets; Humans; Lymphocyte Activation; Purpura, Thrombocytopenic; Quinidine; Quinine | 1980 |
Studies on quinine- and quinidine-dependent antibodies against platelets and their reaction with platelets in the Bernard-Soulier syndrome.
Topics: Antibodies; Blood Coagulation Disorders; Blood Platelets; Complement Fixation Tests; Fluorescent Antibody Technique; Humans; Immunoglobulin G; Purpura, Thrombocytopenic; Quinidine; Quinine; Receptors, Fc; Syndrome; Thrombocytopenia | 1982 |
Liquid chromatographic determination of quinidine in serum and urine.
Topics: Chromatography, Liquid; Humans; Quinidine; Quinine; Temperature | 1982 |
Visual disturbances associated with quinidine and quinine.
Topics: Aged; Diagnosis, Differential; Female; Humans; Ischemic Attack, Transient; Male; Migraine Disorders; Quinidine; Quinine; Vision Disorders | 1981 |
Electrophysiological effects of the optical isomers of disopyramide and quinidine in the dog. Dependence on stereochemistry.
Topics: Action Potentials; Animals; Disopyramide; Dogs; Electrophysiology; Female; Male; Purkinje Fibers; Pyridines; Quinidine; Quinine; Stereoisomerism; Time Factors | 1981 |
Identification of new urinary metabolites in man of quinine using methane chemical ionization gas chromatography-mass spectrometry.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Methane; Quinidine; Quinine | 1981 |
In vitro study of drug-induced granulocytopenia.
Topics: Agranulocytosis; Amodiaquine; Bone Marrow; Culture Techniques; Female; Humans; Male; Middle Aged; Quinidine; Quinine | 1980 |
High-performance liquid chromatographic separation and isolation of quinidine and quinine metabolites in rat urine.
Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Male; Quinidine; Quinine; Rats | 1980 |
Effects of selected drugs on serum digoxin concentration in dogs.
Topics: Acetaminophen; Animals; Aspirin; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ibuprofen; Indomethacin; Male; Metabolic Clearance Rate; Quinidine; Quinine; Time Factors | 1980 |
[Paradoxic response to disopyramide and quinidine (author's transl)].
Topics: Adult; Aged; Disopyramide; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Mitral Valve; Pyridines; Quinidine; Quinine; Tachycardia; Ventricular Fibrillation | 1980 |
Further studies of the human platelet receptor for quinine- and quinine-dependent antibodies.
Topics: Antibodies; Antibody Specificity; Blood Platelet Disorders; Blood Platelets; Cell Membrane; Chromatography, Affinity; Glycoproteins; Humans; Quinidine; Quinine; Receptors, Drug; Solubility | 1981 |
The glycoprotein Ib-IX complex-specific monoclonal antibody SZ1 binds to a conformation-sensitive epitope on glycoprotein IX: implications for the target antigen of quinine/quinidine-dependent autoantibodies.
Topics: Animals; Antibodies, Monoclonal; Autoantibodies; Autoantigens; Autoimmune Diseases; Cell Line, Transformed; Chlorocebus aethiops; CHO Cells; Cricetinae; Epitopes; Formaldehyde; L Cells; Mice; Platelet Membrane Glycoproteins; Polymers; Protein Conformation; Quinidine; Quinine; Thrombocytopenia; Transfection | 1995 |
A novel action of quinine and quinidine on the membrane conductance of neurons from the vertebrate retina.
Topics: Animals; Calcium; Electric Conductivity; Extracellular Space; Gap Junctions; In Vitro Techniques; Ion Channel Gating; Ion Channels; Neurons; Patch-Clamp Techniques; Quinidine; Quinine; Retina; Skates, Fish | 1994 |
Quinine sensitive changes in cellular Na+ and K+ homeostasis of COS-7 cells caused by a lipophilic phenol red impurity.
Topics: Animals; Cell Line; Cells, Cultured; Drug Contamination; Gallic Acid; Homeostasis; Humans; Ion Channels; Phenolphthalein; Phenolphthaleins; Phenolsulfonphthalein; Potassium; Quinidine; Quinine; Sodium; Sulfonamides | 1995 |
Characterisation of Ca(2+)-dependent inwardly rectifying K+ currents in HeLa cells.
Topics: Adenosine Triphosphate; Barium; Bradykinin; Calcium; Cations, Monovalent; Cell Membrane Permeability; Charybdotoxin; Edetic Acid; Electric Conductivity; HeLa Cells; Histamine; Humans; Magnesium; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Quinidine; Quinine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Lupus anticoagulant in the elderly may be associated with both quinine and quinidine usage.
Topics: Aged; Aged, 80 and over; Antiphospholipid Syndrome; Female; Humans; Lupus Coagulation Inhibitor; Male; Quinidine; Quinine; Retrospective Studies | 1995 |
The ACh-induced whole-cell currents in sheep parotid secretory cells. Do BK channels really carry the ACh-evoked whole-cell K+ current?
Topics: 4-Aminopyridine; Acetylcholine; Animals; Barium; Cell Membrane; Chlorides; Parotid Gland; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Sensitivity and Specificity; Sheep; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1995 |
Determinants of antiarrhythmic drug action. Electrostatic and hydrophobic components of block of the human cardiac hKv1.5 channel.
Topics: Anti-Arrhythmia Agents; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Potassium Channel Blockers; Quaternary Ammonium Compounds; Quinidine; Quinine; Tetraethylammonium Compounds | 1995 |
Regulation of [Na+]i in resting and stimulated submandibular salivary ducts.
Topics: Amiloride; Animals; Barium Compounds; Carbachol; Ion Transport; Male; Ouabain; Quinidine; Quinine; Rats; Sodium; Submandibular Gland; Tetraethylammonium; Tetraethylammonium Compounds | 1995 |
Effects of K+ channel blockers on inwardly and outwardly rectifying whole-cell K+ currents in sheep parotid secretory cells.
Topics: Animals; Barium; Cesium; Charybdotoxin; In Vitro Techniques; Lidocaine; Membrane Potentials; Parotid Gland; Potassium; Potassium Channels; Quinidine; Quinine; Scorpion Venoms; Sheep; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1993 |
An inexpensive and sensitive method for the determination of quinidine in plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Parasympatholytics; Quality Control; Quinidine; Quinine; Reference Standards; Spectrophotometry, Ultraviolet | 1995 |
The effects of quinine and quinidine on isolated retinal horizontal cells.
Topics: Animals; Calcium; Cobalt; Electric Conductivity; Halothane; Quinidine; Quinine; Retina; Skates, Fish | 1994 |
Development of a high-performance liquid chromatographic method for the analysis of enatiomer/enantiomer interaction in oxidative metabolism of bunitrolol in rat liver microsomes.
Topics: Adrenergic beta-Antagonists; Animals; Chromatography, High Pressure Liquid; Debrisoquin; Gas Chromatography-Mass Spectrometry; Male; Microsomes, Liver; Oxidation-Reduction; Propanolamines; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism | 1994 |
The chemical and immunoglobulin structural features necessary for reactions of quinine-dependent antibodies to neutrophils.
Topics: Autoantibodies; Cinchona Alkaloids; Flow Cytometry; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Immunosorbent Techniques; Neutrophils; Quinidine; Quinine; Quinolinic Acid | 1995 |
Quinine and quinidine inhibit and reveal heterogeneity of K-Cl cotransport in low K sheep erythrocytes.
Topics: Animals; Calcimycin; Carrier Proteins; Cell Death; Chlorides; Dose-Response Relationship, Drug; Erythrocytes; Hemoglobins; K Cl- Cotransporters; Magnesium; Potassium; Quinidine; Quinine; Rubidium; Sheep; Symporters | 1994 |
Reversal agent inhibition of the multidrug resistance pump in human leukemic lymphoblasts.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Drug Resistance; Humans; Leukemia; Membrane Glycoproteins; Propranolol; Propylamines; Quinidine; Quinine; Rhodamine 123; Rhodamines; Stereoisomerism; Tumor Cells, Cultured | 1994 |
Epoxide metabolite of quinine and inhibition of the multidrug resistance pump in human leukemic lymphoblasts.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Drug Resistance, Multiple; Epoxy Compounds; Humans; Leukemia, Lymphoid; Oxidation-Reduction; Quinidine; Quinine; Rhodamine 123; Rhodamines; Tumor Cells, Cultured | 1994 |
Characterization of cimetidine transport in LLCPK1 cells.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Azides; Biological Transport; Carrier Proteins; Cell Line; Cimetidine; Guanidine; Guanidines; Kidney; Macrolides; Microscopy, Fluorescence; Models, Biological; Niacinamide; Proton-Translocating ATPases; Quinidine; Quinine; Sodium Azide; Sodium-Hydrogen Exchangers; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia.
Topics: Autoimmune Diseases; Blood Coagulation Factors; Blood Coagulation Tests; Blood Platelets; Flow Cytometry; Heparin; Humans; Immunoglobulin G; Quinidine; Quinine; Serotonin; Thrombocytopenia; Thrombosis | 1994 |
Dextromethorphan metabolism in rat: interstrain differences and the fate of individually administered oxidative metabolites.
Topics: Animals; Biotransformation; Dealkylation; Dextromethorphan; Female; Male; Oxidation-Reduction; Quinidine; Quinine; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution | 1994 |
Quinine and quinidine photoproducts can be identical.
Topics: Chromatography, High Pressure Liquid; Cross Reactions; Dermatitis, Photoallergic; Humans; Photochemistry; Photosensitivity Disorders; Quinidine; Quinine; Ultraviolet Rays | 1994 |
Characterisation of praziquantel metabolism by rat liver microsomes using cytochrome P450 inhibitors.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Diphenhydramine; Hydroxylation; Kinetics; Male; Microsomes, Liver; Praziquantel; Quinidine; Quinine; Rats; Rats, Sprague-Dawley | 1994 |
ATP-stimulated electrolyte and mucin secretion in the human intestinal goblet cell line HT29-Cl.16E.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Barium; Cell Line; Chloride Channels; Chlorides; Humans; Intestinal Mucosa; Mucins; Potassium Channels; Quinidine; Quinine | 1994 |
Quinine impairs quinidine clearance in rat perfused liver.
Topics: Animals; Depression, Chemical; In Vitro Techniques; Liver; Male; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1993 |
An evaluation of cytochrome P450 isoform activities in the female dark agouti (DA) rat: relevance to its use as a model of the CYP2D6 poor metaboliser phenotype.
Topics: Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Isoenzymes; Kinetics; Metoprolol; Microsomes, Liver; Mixed Function Oxygenases; Phenotype; Quinidine; Quinine; Rats; Rats, Wistar; Substrate Specificity | 1994 |
[Thrombocytopenia due to therapeutic drugs].
Topics: Aspirin; Blood Platelets; Cephalosporins; Heparin; Humans; Immunoglobulin G; Platelet Count; Quinidine; Quinine; Thrombocytopenia | 1993 |
Gender-associated differences in rat renal tubular amantadine transport and absence of stereoselective transport inhibition by quinine and quinidine in distal tubules.
Topics: Amantadine; Animals; Biological Transport; Female; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Sex Characteristics; Stereoisomerism | 1993 |
Detection of clonal platelet antibodies in immunologically-mediated thrombocytopenias: association with circulating clonal/oligoclonal B cells.
Topics: Adult; Aged; Antibody Specificity; Autoantibodies; Autoimmune Diseases; B-Lymphocytes; Blood Platelets; Child; Clone Cells; Female; Flow Cytometry; Gene Rearrangement; Humans; Immunoglobulin Light Chains; Male; Middle Aged; Quinidine; Quinine; Thrombocytopenia | 1993 |
Studies on cytochrome P450 responsible for oxidative metabolism of imipramine in human liver microsomes.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Electrophoresis, Polyacrylamide Gel; Humans; Imipramine; Immunoblotting; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Propranolol; Quinidine; Quinine; Testosterone; Troleandomycin | 1993 |
Column liquid chromatographic analysis of quinine in human plasma, saliva and urine.
Topics: Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Primaquine; Quinidine; Quinine; Saliva; Spectrophotometry, Ultraviolet | 1993 |
Metabolism of quinine in man: identification of a major metabolite, and effects of smoking and rifampicin pretreatment.
Topics: Antimalarials; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Glucuronates; Humans; Quinidine; Quinine; Rifampin; Smoking | 1995 |
Effects of the quinoline derivatives quinine, quinidine, and chloroquine on neuromuscular transmission.
Topics: Animals; Cholinesterase Inhibitors; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Motor Endplate; Neuromuscular Junction; Patch-Clamp Techniques; Quinidine; Quinine; Quinolones; Rats; Receptors, Presynaptic; Synaptic Transmission | 1996 |
Stereoselective effects of the enantiomers, quinidine and quinine, on depolarization- and agonist-mediated responses in rat isolated aorta.
Topics: Animals; Aorta; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Endothelins; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Serotonin; Stereoisomerism | 1996 |
Potent block of volume-activated chloride currents in endothelial cells by the uncharged form of quinine and quinidine.
Topics: Animals; Anti-Arrhythmia Agents; Antimalarials; Cattle; Cell Line; Cell Size; Chloride Channels; Endothelium, Vascular; Ion Channel Gating; Patch-Clamp Techniques; Quinidine; Quinine; Stereoisomerism | 1996 |
Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance.
Topics: Animals; Anisoles; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Glycosylation; Insecticides; Larva; Lepidoptera; Lethal Dose 50; Molecular Weight; Piperonyl Butoxide; Quinidine; Quinine; Thiocarbamates; Vinblastine | 1996 |
In-vitro metabolic interaction of bunitrolol enantiomers in rabbit liver microsomes.
Topics: Adrenergic beta-Antagonists; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Propanolamines; Quinidine; Quinine; Rabbits; Rats; Rats, Wistar; Species Specificity; Stereoisomerism | 1996 |
Chloroquine, quinine and quinidine inhibit calcium release from macrophage intracellular stores by blocking inositol 1,4,5-trisphosphate binding to its receptor.
Topics: Animals; Antimalarials; Calcium; Calcium Channels; Cell Compartmentation; Chloroquine; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Macrophages, Peritoneal; Mice; Protein Binding; Quinidine; Quinine; Receptors, Cytoplasmic and Nuclear | 1997 |
X-ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity.
Topics: Antimalarials; Crystallography, X-Ray; Heart Diseases; Hydrogen Bonding; Molecular Conformation; Phenanthrenes; Quinidine; Quinine; Stereoisomerism | 1997 |
Evidence for involvement of human CYP3A in the 3-hydroxylation of quinine.
Topics: Antimalarials; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Isoenzymes; Kinetics; Male; Microsomes, Liver; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating; Quinidine; Quinine | 1997 |
Specific binding of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6.
Topics: Carrier Proteins; Cytochrome P-450 CYP2D6; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gene Expression; Humans; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Mitochondria; Nerve Tissue Proteins; Piperazines; Quinidine; Quinine; Saccharomyces cerevisiae | 1997 |
Characterization of delayed rectifier Kv channels in oligodendrocytes and progenitor cells.
Topics: 4-Aminopyridine; Animals; Cell Differentiation; Cell Line; Delayed Rectifier Potassium Channels; Humans; In Situ Hybridization; Ion Transport; Kidney; Kv1.2 Potassium Channel; Kv1.4 Potassium Channel; Kv1.5 Potassium Channel; Macromolecular Substances; Multigene Family; Nerve Tissue Proteins; Oligodendroglia; Oligonucleotides, Antisense; Patch-Clamp Techniques; Polymerase Chain Reaction; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quaternary Ammonium Compounds; Quinidine; Quinine; Rats; Recombinant Fusion Proteins; RNA, Messenger; Stem Cells; Tetraethylammonium; Transfection | 1997 |
Effects of potassium channel blockers on the acetylcholine-induced currents in dissociated outer hair cells of guinea pig cochlea.
Topics: 4-Aminopyridine; Acetylcholine; Analgesics, Non-Narcotic; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hair Cells, Auditory, Outer; Male; Nicotinic Antagonists; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Scorpion Venoms; Tetraethylammonium; Tubocurarine | 1997 |
Involvement of CYP2D1 in the metabolism of carteolol by male rat liver microsomes.
Topics: Adrenergic beta-Antagonists; Animals; Antibodies; Carteolol; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Male; Microsomes, Liver; NADP; Quinidine; Quinine; Rats; Rats, Sprague-Dawley | 1997 |
Mutual inhibition between quinine and etoposide by human liver microsomes. Evidence for cytochrome P4503A4 involvement in their major metabolic pathways.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Etoposide; Humans; Ketoconazole; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, O-Demethylating; Quinidine; Quinine; Troleandomycin | 1998 |
The stereoisomers quinine and quinidine exhibit a marked stereoselectivity in the inhibition of hepatobiliary transport of cardiac glycosides.
Topics: Animals; Biliary Tract; Biological Transport; Calcium Channel Blockers; Cardiac Glycosides; Cardiotonic Agents; Digoxin; Drug Interactions; Liver; Male; Metabolic Clearance Rate; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes.
Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; In Vitro Techniques; Male; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
High-performance liquid chromatographic method for the determination of the major quinine metabolite, 3-hydroxyquinine, in plasma and urine.
Topics: Chromatography, High Pressure Liquid; Humans; Quinidine; Quinine; Sensitivity and Specificity | 1998 |
A recombinant soluble form of the integrin alpha IIb beta 3 (GPIIb-IIIa) assumes an active, ligand-binding conformation and is recognized by GPIIb-IIIa-specific monoclonal, allo-, auto-, and drug-dependent platelet antibodies.
Topics: Antibodies, Monoclonal; Autoantibodies; Dimerization; Humans; Isoantibodies; Ligands; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Conformation; Quinidine; Quinine; Recombinant Proteins; Solubility; Sulfamethoxazole; Thrombocytopenia | 1998 |
An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies.
Topics: Aged; Animals; Anti-Ulcer Agents; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases; Blood Platelets; CHO Cells; Cimetidine; Cricetinae; Cricetulus; Epitopes; Famotidine; Female; Flow Cytometry; Histamine H2 Antagonists; Humans; Molecular Structure; Nizatidine; Platelet Glycoprotein GPIb-IX Complex; Precipitin Tests; Protein Conformation; Quinidine; Quinine; Ranitidine; Recombinant Fusion Proteins; Structure-Activity Relationship; Thrombocytopenia; Transfection | 1998 |
Investigation of the presynaptic effects of quinine and quinidine on the release and uptake of monoamines in rat brain tissue.
Topics: Animals; Biogenic Monoamines; Brain; Dopamine; In Vitro Techniques; Male; Nerve Tissue Proteins; Norepinephrine; Paroxetine; Presynaptic Terminals; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Serotonin; Synaptosomes | 1998 |
Inhibitory effects of quinidine and quinine on liver microsome oxidation enzymes in man and rat.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Humans; Male; Microsomes, Liver; Mixed Function Oxygenases; Quinidine; Quinine; Rats; Species Specificity | 1996 |
Influence of substrate structure on substrate binding to the renal organic cation/H+ exchanger.
Topics: Acridines; Animals; Antiporters; Carbon Radioisotopes; Cations; Ephedrine; Ion Transport; Kidney Cortex; Microvilli; Molecular Structure; Nicotine; Pyridinium Compounds; Quinidine; Quinine; Quinolinium Compounds; Rabbits; Stereoisomerism; Structure-Activity Relationship; Tetraethylammonium | 1999 |
[Pulmonary manifestations associated with malaria].
Topics: Adult; Anti-Bacterial Agents; Antimalarials; Bronchitis; Child; Chloroquine; Female; Humans; Infant, Newborn; Lung Diseases; Malaria, Falciparum; Male; Mefloquine; Oxygen Inhalation Therapy; Phenanthrenes; Pleurisy; Pregnancy; Pregnancy Complications, Parasitic; Pulmonary Edema; Quinidine; Quinine; Respiratory Distress Syndrome, Newborn; Travel | 1998 |
Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21.
Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; Calcium Channel Blockers; Cholinergic Antagonists; Cyclohexanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Inhibitors; Humans; Isoenzymes; Liver; Lymphocytes; Male; Microsomes, Liver; Phenylacetates; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Troleandomycin | 1999 |
Potassium conductances in isolated single cells from Xenopus laevis colonic epithelium.
Topics: Animals; Barium; Cesium; Colon; Epithelial Cells; Female; Hydrogen-Ion Concentration; Ion Transport; Lidocaine; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Tetraethylammonium; Verapamil; Xenopus laevis | 1999 |
[Quinine/quinidine treatment of cramps of the calf is not supported by the Pharmaceutical Product Agency].
Topics: Humans; Leg; Muscle Cramp; Muscle Relaxants, Central; Quinidine; Quinine | 1999 |
Enantioselective anion exchangers based on cinchona alkaloid-derived carbamates: influence of C8/C9 stereochemistry on chiral recognition.
Topics: Antimalarials; Carbamates; Chromatography, High Pressure Liquid; Cinchona Alkaloids; Crystallography, X-Ray; Models, Chemical; Molecular Conformation; Quinidine; Quinine; Stereoisomerism | 1999 |
Renal excretion mechanism of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Biological Transport; Carbon Radioisotopes; Dogs; Glomerular Filtration Rate; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; Microvilli; Quinidine; Quinine; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Secretory Rate; Stereoisomerism | 1999 |
Quinolines attenuate PAF-induced pulmonary pressor responses and edema formation.
Topics: Airway Resistance; Animals; Aspirin; Benzoquinones; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Chloroquine; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; In Vitro Techniques; Interleukin-6; Lipoxygenase Inhibitors; Lung; Male; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Pulmonary Circulation; Pulmonary Edema; Quinidine; Quinine; Quinolines; Rats; Rats, Wistar; Receptors, Thromboxane; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction | 1999 |
Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Enzyme Inhibitors; Kinetics; Ligands; Metoprolol; Mutagenesis, Site-Directed; Oxidation-Reduction; Propranolol; Quinidine; Quinine; Serine; Substrate Specificity; Yeasts | 2000 |
Comparative in vitro metabolism of indinavir in primates--a unique stereoselective hydroxylation in monkey.
Topics: Animals; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; HIV Protease Inhibitors; Humans; Hydroxylation; Indinavir; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Molecular Conformation; Molecular Structure; Primates; Quinidine; Quinine | 2000 |
Stereospecificity of antibody: quinine, the optical isomer of quinidine and anti-malarial drug chloroquine do not cross-react with quinidine immunoassays.
Topics: Antibodies; Antimalarials; Chloroquine; Cross Reactions; Humans; Immunoassay; Quinidine; Quinine; Stereoisomerism | 2000 |
Interaction of chloroquine and its analogues with heme: An isothermal titration calorimetric study.
Topics: Amodiaquine; Antimalarials; Binding Sites; Calorimetry; Chloroquine; Hemin; Hydrogen-Ion Concentration; Mefloquine; Octoxynol; Quinidine; Quinine; Solubility; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Titrimetry | 2000 |
Enantioseparation of anionic analytes by non-aqueous capillary electrophoresis using quinine and quinidine derivatives as chiral counter-ions.
Topics: Anions; Electrophoresis, Capillary; Quinidine; Quinine; Sensitivity and Specificity; Stereoisomerism | 2000 |
Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Quinidine; Quinine; Quinones; Reproducibility of Results; Stereoisomerism | 2001 |
Development of stereoselective nonaqueous capillary electrophoresis system for the resolution of cationic and amphoteric analytes.
Topics: Carbamates; Cations; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Indicators and Reagents; Leucine; Mefloquine; Molecular Structure; Nitrobenzoates; Quinidine; Quinine; Stereoisomerism | 2001 |
Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum.
Topics: Acridine Orange; Animals; Antimalarials; Calcium Channel Blockers; Chloroquine; Drug Interactions; Drug Resistance; Fluorescence; Membrane Proteins; Membrane Transport Proteins; Molecular Conformation; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine; Verapamil | 2002 |
Differential inhibition of human CYP1A1 and CYP1A2 by quinidine and quinine.
Topics: Acetaminophen; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Humans; Microsomes, Liver; Oxazines; Phenacetin; Quinidine; Quinine; Rats; Recombinant Proteins; Yeasts | 2001 |
Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance.
Topics: Antimalarials; Artemisinins; Carmustine; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Ethacrynic Acid; Glutathione Transferase; Humans; Isoenzymes; Quinidine; Quinine; Recombinant Proteins; Sesquiterpenes; Tetracycline | 2002 |
Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P-glycoproteins.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Cations; Drug Design; Humans; Immunoblotting; Insecta; Muscarinic Antagonists; Quinidine; Quinine; Rats; Recombinant Proteins | 2002 |
Crystal structure of (-)-mefloquine hydrochloride reveals consistency of configuration with biological activity.
Topics: Animals; Antimalarials; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Mefloquine; Molecular Conformation; Plasmodium falciparum; Quinidine; Quinine; Stereoisomerism | 2002 |
4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine.
Topics: Adrenergic Agents; Antimalarials; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydroxylation; Microsomes; Quinidine; Quinine | 2002 |
Highly selective hydroformylation of the cinchona alkaloids.
Topics: Alcohols; Aldehydes; Catalysis; Cinchona Alkaloids; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Quinidine; Quinine; Rhodium | 2002 |
Solution structures of antimalarial drug-heme complexes.
Topics: Aminoquinolines; Antimalarials; Binding Sites; Chloroquine; Dimerization; Hemin; Hydrogen-Ion Concentration; Macromolecular Substances; Nuclear Magnetic Resonance, Biomolecular; Protons; Quinidine; Quinine; Solutions; Thermodynamics | 2002 |
Effects of quinine and quinidine on the transient outward and on the L-type Ca(2+) current in rat ventricular cardiomyocytes.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channels; Calcium Channels, L-Type; Female; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2002 |
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Microsomes, Liver; Pharmacokinetics; Quinidine; Quinine | 2002 |
Quinine pharmacokinetics in chronic haemodialysis patients.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Female; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Muscle Relaxants, Central; Orosomucoid; Quinidine; Quinine; Quinones; Renal Dialysis | 2002 |
Highly stereoselective, uniformly sized molecularly imprinted polymers for cinchona alkaloids in hydro-organic mobile phases.
Topics: Chromatography, High Pressure Liquid; Cinchona Alkaloids; Polymers; Quinidine; Quinine; Thermodynamics | 2003 |
[Stereoselectivity in O-demethylation of trans tramadol in rat liver microsomes in vitro].
Topics: Analgesics, Opioid; Animals; Cell Separation; Male; Microsomes, Liver; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tramadol | 2002 |
Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain.
Topics: Binding Sites; Cation Transport Proteins; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Membrane Proteins; Phosphodiesterase Inhibitors; Point Mutation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Structure, Tertiary; Pyrazines; Quinidine; Quinine; Quinolines; Trans-Activators; Transcriptional Regulator ERG; Tyrosine | 2003 |
Inhibition of cytochrome P450 2D6: structure-activity studies using a series of quinidine and quinine analogues.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Esters; Gas Chromatography-Mass Spectrometry; Hydrogen Bonding; Protein Binding; Quaternary Ammonium Compounds; Quinidine; Quinine; Spectrophotometry; Stereoisomerism; Structure-Activity Relationship | 2003 |
A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord.
Topics: Amino Acid Sequence; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Arachidonic Acid; Barium; Cell Line; Cloning, Molecular; Docosahexaenoic Acids; Electrophysiology; Ethanolamines; Fatty Acids; Fatty Acids, Nonesterified; Glyburide; Humans; Hydrogen-Ion Concentration; Lidocaine; Mice; Models, Biological; Molecular Sequence Data; Patch-Clamp Techniques; Phylogeny; Potassium Channels; Propafenone; Protein Structure, Tertiary; Quinidine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Tissue Distribution; Transfection | 2003 |
Enantiomeric separation of N-protected amino acids by non-aqueous capillary electrophoresis with dimeric forms of quinine and quinidine derivatives serving as chiral selectors.
Topics: Amino Acids; Electrophoresis, Capillary; Indicators and Reagents; Polymers; Quinidine; Quinine; Spectrophotometry, Ultraviolet; Stereoisomerism | 2002 |
Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.
Topics: Animals; Benzoflavones; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Hepatocytes; Inhibitory Concentration 50; Kinetics; Male; Methylation; Microsomes, Liver; Oxidoreductases, O-Demethylating; Protein Binding; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Troleandomycin | 2003 |
High-performance liquid chromatographic method for the determination of quinine and 3-hydroxyquinine in blood samples dried on filter paper.
Topics: Chromatography, High Pressure Liquid; Humans; Paper; Quinidine; Quinine; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Macroporous monolithic chiral stationary phases for capillary electrochromatography: New chiral monomer derived from cinchona alkaloid with enhanced enantioselectivity.
Topics: Amino Acids; Chromatography, Liquid; Cinchona Alkaloids; Cross-Linking Reagents; Electrophoresis, Capillary; Fluorescence; Methacrylates; Nitriles; Porosity; Quinidine; Quinine; Reproducibility of Results; Stereoisomerism | 2003 |
Action of sheep liver homogenates on quinine, quinidine, cinchonine and cinchonidine.
Topics: Animals; Cinchona Alkaloids; Liver; Quinidine; Quinine; Sheep; Sheep, Domestic | 1952 |
Observations on cases of thrombocytopenic purpura due to quinine, sulphamezathine, and quinidine.
Topics: Humans; Purpura; Purpura, Thrombocytopenic; Quinidine; Quinine; Sulfamethazine; Sulfanilamide; Sulfanilamides; Sulfonamides; Thrombocytopenia | 1953 |
The action of quinine and quinidine on the contractions of striated muscle.
Topics: Humans; Muscle, Skeletal; Muscle, Striated; Muscles; Quinidine; Quinine | 1955 |
[Micro-determination of quinine and quinidine in blood serum by the intermediary of a dye combination formed with rose bengal].
Topics: Coloring Agents; Humans; Quinidine; Quinine; Rose Bengal; Serum | 1957 |
Immunoreactions involving platelets. III. Quantitative aspects of platelet agglutination, inhibition of clot retraction, and other reactions caused by the antibody of quinidine purpura.
Topics: Agglutination; Animals; Antibodies; Antibody Formation; Blood Platelets; Clot Retraction; Complement System Proteins; Dogs; Guinea Pigs; Humans; Purpura; Purpura, Thrombocytopenic; Quinidine; Quinine; Thrombocytopenia | 1958 |
[Results of treatment of remote disorders of rhythm of cardiac activity with quinidine, quinine bromide and novocainamide].
Topics: Arrhythmias, Cardiac; Bromides; Niacin; Nicotinic Acids; Procainamide; Quinidine; Quinine | 1961 |
[On acute quinine poisoning; clinical course and therapy].
Topics: Cardiovascular Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Quinidine; Quinine | 1961 |
Prophylactic quinidine after myocardial infarction.
Topics: Arrhythmias, Cardiac; Biomedical Research; Cardiovascular Diseases; Humans; Myocardial Infarction; Quinidine; Quinine | 1961 |
[Experimental studies on the effect of quinine, quinidine and procaine amide on ECG and on oxygen consumption by the heart muscle].
Topics: Electrocardiography; Humans; Myocardium; Oxygen Consumption; Procainamide; Procaine; Quinidine; Quinine | 1961 |
Reaction between DNA and quinacrine and other antimalarials.
Topics: Antimalarials; Chloroquine; DNA; Quinacrine; Quinidine; Quinine | 1962 |
[Regulatory treatment of complete arrhythmia].
Topics: Arrhythmias, Cardiac; Humans; Quinidine; Quinine | 1963 |
The effect of quinidine and quinine on nitrogen and electrolyte balance (protein anabolic effect) and on glucose utilization.
Topics: Anabolic Agents; Calcium; Calcium, Dietary; Chlorides; Glucose; Guanidines; Guanine; Nitrogen; Phosphorus; Potassium; Proteins; Quinidine; Quinine; Sodium; Sodium, Dietary; Water-Electrolyte Balance | 1963 |
Rapid diagnosis of drug-induced thrombocytopenic purpura. Report of three cases due to quinine, quinidine, and Dilantin.
Topics: Humans; Hydantoins; Phenytoin; Purpura; Purpura, Thrombocytopenic; Quinidine; Quinine; Thrombocytopenia | 1962 |
The cytotoxic effect of quinine, quinidine and hydroxyethylapocupreine upon mammalian cell cultures.
Topics: Animals; Humans; Quinidine; Quinine | 1963 |
SOME CONSIDERATIONS IN POISONING WITH QUININE AND RELATED COMPOUNDS.
Topics: Humans; Quinidine; Quinine; Toxicology | 1963 |
BIODYNAMICS OF THIOUREA-ALKALOID COMBINATIONS.
Topics: Absorption; Alkaloids; Anti-Bacterial Agents; Blood Chemical Analysis; Caffeine; Intestines; Metabolism; Penicillins; Pharmacology; Quinidine; Quinine; Rats; Research; Salicylic Acid; Thiourea | 1963 |
A MECHANISM OF CELL DESTRUCTION IN INDIVIDUALS SENSITIZED TO FOREIGN ANTIGENS AND ITS IMPLICATIONS IN AUTO-IMMUNITY. COMBINED CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH.
Topics: Anemia; Anemia, Hemolytic; Antigens; Autoantibodies; Complement Fixation Tests; Drug Hypersensitivity; Erythrocytes; Humans; Leukocytes; National Institutes of Health (U.S.); Purpura; Quinidine; Quinine; United States | 1964 |
[OPHTHALMOLOGICAL COMPLICATIONS OF CERTAIN GENERAL THERAPEUTICS].
Topics: Acetazolamide; Adrenal Cortex Hormones; Anthelmintics; Arsenicals; Barbiturates; Chloroquine; Chlorpromazine; Dinitrophenols; Ophthalmology; Parasympathomimetics; Quinidine; Quinine; Streptomycin; Sulfonamides; Toxicology; Tranquilizing Agents; Vitamin D; Vitamins | 1964 |
DRUG-INDUCED THROMBOCYTOPENIA.
Topics: Acetazolamide; Anticonvulsants; Arsphenamine; Chloramphenicol; Chlorothiazide; Colchicine; Gold; Hydantoins; Hypoglycemic Agents; Meprobamate; Perchlorates; Phenothiazines; Phenylbutazone; Pyrimethamine; Quinacrine; Quinidine; Quinine; Ristocetin; Streptomycin; Sulfonamides; Thrombocytopenia; Toxicology | 1964 |
[TREATMENT OF MYASTHENIA].
Topics: Adrenocorticotropic Hormone; Cyclopropanes; Epinephrine; Galantamine; Humans; Hypnotics and Sedatives; Isoflurophate; Morphine; Myasthenia Gravis; Neostigmine; Neuromuscular Nondepolarizing Agents; Nitrogen; Organophosphate Poisoning; Parasympathomimetics; Phosphorus; Poisons; Quinidine; Quinine; Surgical Procedures, Operative; Thymus Gland | 1964 |
[ANALYSIS OF GALENIC PREPARATIONS. QUINA-KOLA SYRUP].
Topics: Caffeine; Chemistry, Pharmaceutical; Cinchona; Pharmacy; Quinidine; Quinine; Research | 1964 |
[THE HEART AND POISONINGS].
Topics: Chloroquine; Diagnosis; Digitalis Glycosides; Heart; Heart Failure; Imipramine; Prognosis; Quinidine; Quinine; Toxicology | 1964 |
FACTORIAL STUDY OF THIOUREA ADJUVANTS ON QUININE AND QUINIDINE ABSORPTION.
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Biomedical Research; Buffers; Factor Analysis, Statistical; Fasting; Intestinal Absorption; Pharmacology; Phenylthiourea; Quinidine; Quinine; Rats; Research; Thiourea | 1964 |
STEREOSPECIFIC HYDROGENATIONS USING PALLADIUM-ON-SILICA GEL CATALYSTS.
Topics: Catalysis; Chemistry, Pharmaceutical; Cinchona; Hydrogenation; Palladium; Pharmacy; Quinidine; Quinine; Research; Silica Gel; Silicon Dioxide | 1964 |
[ARRHYTMIA: DIAGNOSIS AND TREATMENT].
Topics: Amyl Nitrite; Arrhythmias, Cardiac; Atropine; Diagnosis; Digitalis Glycosides; Drug Therapy; Ephedrine; Epinephrine; Humans; Ouabain; Physostigmine; Pilocarpine; Quinidine; Quinine; Strophanthins | 1964 |
COMPARISON OF IMMUNOLOGIC AND IDIOPATHIC THROMBOCYTOPENIA.
Topics: Allergy and Immunology; Antibody Formation; Antigen-Antibody Reactions; Autoantibodies; Blood Transfusion; Drug Hypersensitivity; gamma-Globulins; Humans; Immunoelectrophoresis; Immunoglobulin G; Isoantibodies; Purpura, Thrombocytopenic; Quinidine; Quinine; Thrombocytopenia; Toxicology | 1964 |
THIN-LAYER CHROMATOGRAPHY OF CINCHONA ALKALOIDS II. QUALITATIVE EXAMINATION OF DIHYDRO-BASES OF THE CINCHONA ALDALOIDS IN COMMERCIAL PRODUCTS.
Topics: Chromatography; Chromatography, Thin Layer; Cinchona; Cinchona Alkaloids; Quinidine; Quinine; Research | 1965 |
Effect of orally administered quinine and quinidine on apparent values for urinary catecholamines.
Topics: Catecholamines; Hematologic Tests; Humans; Quinidine; Quinine | 1960 |
A comparison of activity of quinine and quinidine on the isolated electrically stimulated rat ventricle strip.
Topics: Animals; Electricity; Heart; Heart Ventricles; Quinidine; Quinine; Rats | 1961 |
[On the differentiation between quinine and quinidine].
Topics: Quinidine; Quinine | 1961 |
Catalytic asymmetric total syntheses of quinine and quinidine.
Topics: Catalysis; Quinidine; Quinine; Stereoisomerism | 2004 |
Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.
Topics: Animals; Anti-Infective Agents; Biguanides; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Dogs; Enzyme Inhibitors; Microsomes, Liver; NADP; Oxidation-Reduction; Quinidine; Quinine; Spectrometry, Mass, Electrospray Ionization | 2004 |
Quinine/quinidine-induced thrombocytopenia: a great imitator.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Arrhythmia Agents; Antibodies; Female; Humans; Male; Middle Aged; Muscle Cramp; Muscle Relaxants, Central; Quinidine; Quinine; Thrombocytopenia | 2004 |
The antiaccelerator cardiac action of quinine and quinidine.
Topics: Heart; Heart Rate; Humans; Myocardial Contraction; Quinidine; Quinine | 1950 |
[Action of quinine and of quinidine on cholinesterase].
Topics: Cholinesterase Inhibitors; Humans; Quinidine; Quinine | 1951 |
Action of quinine of the renal circulation in dogs.
Topics: Animals; Dogs; Humans; Quinidine; Quinine; Renal Circulation | 1952 |
[Mentality of malaria patients and modality of quinine therapy].
Topics: Humans; Malaria; Quinidine; Quinine | 1952 |
Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system.
Topics: Antifungal Agents; Antimalarials; Catalysis; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Estrogen Antagonists; Ethinyl Estradiol; Flavanones; Hormone Antagonists; Humans; Immunosuppressive Agents; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Mifepristone; NADPH-Ferrihemoprotein Reductase; Phospholipids; Quinidine; Quinine; Tacrolimus | 2004 |
The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.
Topics: Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Cycloheximide; Drug Resistance, Multiple, Fungal; Gene Deletion; Genes, Fungal; Mefloquine; Mutation; Quinacrine; Quinidine; Quinine; Saccharomyces cerevisiae; Transcription, Genetic | 2004 |
Sympatholytic effects of quinine and quinidine.
Topics: Humans; Nervous System; Quinidine; Quinine; Sympathetic Nervous System; Sympatholytics | 1950 |
Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Quinidine; Quinine | 2004 |
New general sulfinylating process for asymmetric synthesis of enantiopure sulfinates and sulfoxides.
Topics: Chemistry, Organic; Cinchona Alkaloids; Molecular Structure; Quinidine; Quinine; Stereoisomerism; Sulfinic Acids; Sulfoxides | 2005 |
Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.
Topics: Acids; Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Cytoplasmic Vesicles; Dictyostelium; Drug Resistance, Bacterial; Gene Expression; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Phenotype; Phylogeny; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinidine; Quinine; Quinolines; Transfection | 2005 |
Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors.
Topics: Animals; Antimalarials; Chloroquine; Hair Cells, Auditory, Inner; Quinidine; Quinine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Recombinant Proteins; Xenopus laevis | 2005 |
Confirmation of the structure of (3S)-3-hydroxyquinine: synthesis and X-ray crystal structure of its 9-aceto analogue.
Topics: Crystallography, X-Ray; Molecular Conformation; Molecular Structure; Quinidine; Quinine; Stereoisomerism | 2005 |
Application of solid-phase microextraction in the investigation of protein binding of pharmaceuticals.
Topics: Binding, Competitive; Chromatography, High Pressure Liquid; Ciprofloxacin; Haloperidol; Humans; Kinetics; Naproxen; Nortriptyline; Paclitaxel; Pharmaceutical Preparations; Protein Binding; Quinidine; Quinine; Serum Albumin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Ultrafiltration | 2006 |
Effects of gap junction blockers on human neocortical synchronization.
Topics: 4-Aminopyridine; Adolescent; Adult; Aged; Brain Diseases; Carbenoxolone; Child; Cortical Synchronization; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agents; Gap Junctions; Humans; Membrane Potentials; Middle Aged; Neocortex; Octanols; Organ Culture Techniques; Potassium Channel Blockers; Quinidine; Quinine; Receptors, GABA; Receptors, N-Methyl-D-Aspartate | 2006 |
[Malaria: report of 12 non autochthonous cases].
Topics: Adolescent; Adult; Antimalarials; Diagnosis, Differential; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Quinidine; Quinine; Retrospective Studies | 2006 |
The connexin 36 blockers quinine, quinidine and mefloquine inhibit cortical spreading depression in a rat neocortical slice model in vitro.
Topics: Animals; Cell Communication; Connexins; Cortical Spreading Depression; Dose-Response Relationship, Drug; Gap Junction delta-2 Protein; Gap Junctions; Male; Mefloquine; Membrane Potentials; Models, Neurological; Neocortex; Organ Culture Techniques; Potassium Channel Blockers; Quinidine; Quinine; Rats; Rats, Sprague-Dawley | 2006 |
Crystal and molecular structures of trichloro-cobalt(II) complexes of epiquinine, epiquinidine, and epidihydrocinchonine.
Topics: Antimalarials; Cinchona Alkaloids; Cobalt; Crystallography, X-Ray; Hydrocarbons, Chlorinated; Models, Molecular; Quinidine; Quinine | 2007 |
Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine | 2007 |
One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia--a new paradigm.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents, Non-Steroidal; Cefotetan; Cephalosporins; Child; Child, Preschool; Coombs Test; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Penicillins; Quinidine; Quinine; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Serologic Tests | 2007 |
An improved synthesis of 10,11-didehydro Cinchona alkaloids.
Topics: Cinchona Alkaloids; Magnetic Resonance Spectroscopy; Methods; Molecular Structure; Quinidine; Quinine; Stereoisomerism | 2008 |
A man with tropical travel history, fever, and pulmonary infiltrates.
Topics: Africa, Western; Aged; Animals; Antimalarials; Atovaquone; Doxycycline; Drug Combinations; Fever; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Proguanil; Quinidine; Quinine; Respiratory Distress Syndrome; Travel; Tropical Climate | 2007 |
In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Boron Compounds; Carbamates; Carbon Radioisotopes; Cyclosporine; Drug Interactions; Fluorescent Dyes; Furans; Humans; LLC-PK1 Cells; Positron-Emission Tomography; Quinidine; Quinine; Rats; Sulfonamides; Swine; Verapamil | 2008 |
The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions.
Topics: Animals; Cells, Cultured; Chorda Tympani Nerve; Electric Conductivity; Humans; Ion Channel Gating; Mice; Patch-Clamp Techniques; Quaternary Ammonium Compounds; Quinidine; Quinine; Sucrose; Taste; TRPM Cation Channels | 2008 |
Effects of repeated oral doses of quinine and quinidine on the blood pressure and renal circulation of dogs with experimental neurogenic hypertension.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Cinchona; Dogs; Hypertension; Quinidine; Quinine; Renal Circulation | 1948 |
Application of multivariate methods to the simultaneous Fourier Transform Infrared (FT-IR) spectrometric determination of stereo-isomers; quinine and quinidine.
Topics: Antimalarials; Artificial Intelligence; Calibration; Chemistry, Pharmaceutical; Indicators and Reagents; Least-Squares Analysis; Multivariate Analysis; Principal Component Analysis; Quinidine; Quinine; Software; Solutions; Spectroscopy, Fourier Transform Infrared; Stereoisomerism | 2008 |
Fatal transfusion-transmitted Babesia microti in the Midwest.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Babesia microti; Babesiosis; Clindamycin; Disseminated Intravascular Coagulation; Erythrocyte Transfusion; Fatal Outcome; Female; Heart Failure; Humans; Kidney Failure, Chronic; Middle Aged; Midwestern United States; Quinidine; Quinine; Shock, Septic | 2009 |
Enantioselective complexation of carbamoylated quinine and quinidine with N-blocked amino acids: vibrational and electronic circular dichroism study.
Topics: Amino Acids; Circular Dichroism; Dinitrobenzenes; Glycine; Leucine; Molecular Structure; Quinidine; Quinine; Spectrophotometry, Infrared; Stereoisomerism; Vibration | 2009 |
Quinine amaurosis.
Topics: Blindness; Humans; Quinidine; Quinine | 1948 |
The pharmacology of quinine methiodide.
Topics: Quinidine; Quinine | 1948 |
Pharmacological studies on warm anesthesia; Theophylline, methylene blue, quinine.
Topics: Humans; Methylene Blue; Quinidine; Quinine | 1948 |
Evaluation of quinine in human plasma with a note on the evaluation of quinidine.
Topics: Blood; Humans; Quinidine; Quinine | 1947 |
Insight into the effects of chiral isomers quinidine and quinine on CYP2D6 inhibition.
Topics: Catalytic Domain; Chemistry, Pharmaceutical; Cytochrome P-450 CYP2D6 Inhibitors; Drug Design; Humans; Hydrogen Bonding; Models, Chemical; Molecular Conformation; Protein Binding; Quantitative Structure-Activity Relationship; Quinidine; Quinine; Static Electricity; Stereoisomerism | 2009 |
Expression and functional characterization of choline transporter in human keratinocytes.
Topics: Acetylcholine; Anisoles; Antigens, CD; Biological Transport; Cell Membrane; Cells, Cultured; Choline; Clonidine; Desipramine; Diphenhydramine; Gene Expression Profiling; Humans; Keratinocytes; Membrane Potentials; Octamer Transcription Factor-3; Organic Cation Transport Proteins; p-Aminohippuric Acid; Quinidine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters; Tetraethylammonium; Time Factors; Tritium | 2009 |
Simultaneous liquid chromatographic analysis of ritonavir, quinine and 3-hydroxyquinine in human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Quinidine; Quinine; Reference Standards; Ritonavir; Sensitivity and Specificity | 2009 |
Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice.
Topics: Analgesics, Non-Narcotic; Animals; Carbenoxolone; Cerebral Cortex; Connexins; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Female; Gap Junction delta-2 Protein; In Vitro Techniques; Magnesium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Seizures; Time Factors | 2009 |
Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.
Topics: Animals; Anthelmintics; Female; Gastrointestinal Tract; Gene Expression Profiling; Hemeproteins; Intestinal Mucosa; Liver; Male; Mice; Parasite Egg Count; Quinacrine; Quinidine; Quinine; Schistosoma mansoni; Schistosomiasis mansoni | 2009 |
Practical and highly selective sulfur ylide mediated asymmetric epoxidations and aziridinations using an inexpensive, readily available chiral sulfide. Applications to the synthesis of quinine and quinidine.
Topics: Aziridines; Biological Products; Costs and Cost Analysis; Epoxy Compounds; Quinidine; Quinine; Stereoisomerism; Substrate Specificity; Sulfides; Sulfur | 2010 |
Successful acute and long-term management of electrical storm in Brugada syndrome using orciprenaline and quinine/quinidine.
Topics: Adrenergic Agonists; Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillators, Implantable; Drug Therapy, Combination; Humans; Male; Metaproterenol; Muscle Relaxants, Central; Quinidine; Quinine; Treatment Outcome | 2010 |
Crystal engineering of pharmaceutical Co-crystals: application of methyl paraben as molecular hook.
Topics: Antimalarials; Chemistry, Pharmaceutical; Computer Simulation; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Conformation; Parabens; Quantum Theory; Quinidine; Quinine; Stereoisomerism | 2010 |
The relative value of synthetic quinidine, dihydroquinidine, commercial quinidine, and quinine in the control of cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Humans; Quinidine; Quinine | 1947 |
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Black People; Body Weight; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Female; Genes; Genetic Variation; Haplotypes; Humans; Immunosuppressive Agents; Male; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Quinidine; Quinine; Sex Factors; Uganda | 2010 |
Drug-induced thrombocytopenia for the hospitalist physician with a focus on heparin-induced thrombocytopenia.
Topics: Acute Disease; Algorithms; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Causality; Decision Trees; Diagnosis, Differential; Heparin; Hospitalists; Humans; Medical History Taking; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Quinidine; Quinine; Thrombocytopenia; Time Factors | 2010 |
Malaria in pregnancy: update on emergency management.
Topics: Abortion, Spontaneous; Adult; Anti-Bacterial Agents; Antimalarials; Clindamycin; Female; Humans; Malaria, Vivax; Plasmodium vivax; Pregnancy; Pregnancy Complications, Parasitic; Quinidine; Quinine | 2011 |
Strong detrimental effect of a minute enantiomeric impurity of a chiral selector on the enantioselectivity factor.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Dinitrobenzenes; Molecular Structure; Pharmaceutical Preparations; Quinidine; Quinine; Stereoisomerism | 2010 |
The comparative action of some alkyl hydrocupreidines.
Topics: Humans; Quinidine; Quinine | 1946 |
Studies on antimalarial drugs; the metabolism of quinine and quinidine in birds and mammals.
Topics: Animals; Antimalarials; Birds; Mammals; Quinidine; Quinine | 1945 |
Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system.
Topics: Animals; Antimalarials; Arrhythmias, Cardiac; Guinea Pigs; Heart; Heart Conduction System; Mefloquine; Phenanthrenes; Quinidine; Quinine; Time Factors | 2010 |
Rapid quantification of quinine and its major metabolite (3S)-3-hydroxyquinine in diluted urine by UPLC-MS/MS.
Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Quinidine; Quinine; Reference Standards; Reproducibility of Results; Solid Phase Extraction; Solutions; Tandem Mass Spectrometry | 2011 |
Study of stereoselective interactions of carbamoylated quinine and quinidine with 3,5-dinitrobenzoyl α-amino acids using VCD spectroscopy in the region of C−H stretching vibrations.
Topics: Absorption; Alanine; Amino Acids; Circular Dichroism; Dinitrobenzenes; Glycine; Hydrophobic and Hydrophilic Interactions; Isoleucine; Leucine; Quinidine; Quinine; Stereoisomerism; Valine; Vibration | 2011 |
Genetic epidemiology of induced CYP3A4 activity.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers, Pharmacological; Body Mass Index; Cytochrome P-450 CYP3A; Female; Humans; Hypericum; Middle Aged; Models, Genetic; Plant Extracts; Quinidine; Quinine; Smoking; Surveys and Questionnaires | 2011 |
Rapid and green analytical method for the determination of quinoline alkaloids from Cinchona succirubra based on Microwave-Integrated Extraction and Leaching (MIEL) prior to high performance liquid chromatography.
Topics: Antimalarials; Chromatography, High Pressure Liquid; Cinchona; Cinchona Alkaloids; Green Chemistry Technology; Microwaves; Plant Bark; Plant Extracts; Quinidine; Quinine; Quinolines | 2011 |
Iron(III) protoporphyrin IX complexes of the antimalarial Cinchona alkaloids quinine and quinidine.
Topics: Antimalarials; Cinchona Alkaloids; Iron; Models, Molecular; Molecular Conformation; Protoporphyrins; Quinidine; Quinine; Structure-Activity Relationship; X-Ray Diffraction | 2012 |
Conformational analysis of quinine and its pseudo enantiomer quinidine: a combined jet-cooled spectroscopy and vibrational circular dichroism study.
Topics: Cinchona; Circular Dichroism; Electrons; Gases; Lasers; Models, Molecular; Molecular Conformation; Quantum Theory; Quinidine; Quinine; Spectrum Analysis; Stereoisomerism; Thermodynamics | 2012 |
Genome-wide association study reveals a complex genetic architecture underpinning-induced CYP3A4 enzyme activity.
Topics: Aged; Aged, 80 and over; Biomarkers; Biotransformation; Cytochrome P-450 CYP3A; Enzyme Induction; Female; Genome-Wide Association Study; Genotype; Humans; Hydroxylation; Hypericum; Liver; Middle Aged; Phenotype; Plant Preparations; Quinidine; Quinine; Substrate Specificity; Twins | 2013 |
Relative to quinine and quinidine, their 9-epimers exhibit decreased cytostatic activity and altered heme binding but similar cytocidal activity versus Plasmodium falciparum.
Topics: Antimalarials; Cells, Cultured; Crystallization; Cytostatic Agents; Cytotoxins; Erythrocytes; Heme; Hemeproteins; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kinetics; Mass Spectrometry; Plasmodium falciparum; Quinidine; Quinine; Spectrometry, Fluorescence | 2013 |
Antimalarial interaction of quinine and quinidine with clarithromycin.
Topics: Animals; Antimalarials; Clarithromycin; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium yoelii; Quinidine; Quinine | 2013 |
The sugar meal of the African malaria mosquito Anopheles gambiae and how deterrent compounds interfere with it: a behavioural and neurophysiological study.
Topics: Action Potentials; Analysis of Variance; Animals; Anopheles; Berberine; Caffeine; Chemoreceptor Cells; Feeding Behavior; Female; Fructose; Glucose; Microscopy, Electron, Transmission; Nigeria; Quaternary Ammonium Compounds; Quinidine; Quinine; Sensilla; Sucrose | 2013 |
Synthesis of 9-amino(9-deoxy)epi cinchona alkaloids, general chiral organocatalysts for the stereoselective functionalization of carbonyl compounds.
Topics: Aluminum Compounds; Catalysis; Chemistry Techniques, Synthetic; Cinchona Alkaloids; Hydrogenation; Hydrolysis; Lithium Compounds; Molecular Structure; Oxidation-Reduction; Quinidine; Quinine | 2013 |
Templating effect in DNA proximity ligation enables use of non-bioorthogonal chemistry in biological fluids.
Topics: Aptamers, Nucleotide; Benzaldehydes; Biological Assay; Buffers; Cinchona Alkaloids; Cocaine; DNA; Humans; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Nucleic Acid Conformation; Quinidine; Quinine; Sequence Analysis, DNA; Serum; Urine | 2012 |
Modelling species selectivity in rat and human cytochrome P450 2D enzymes.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Cytochrome P-450 CYP2D6; Humans; Ligands; Molecular Docking Simulation; Molecular Sequence Data; Quinidine; Quinine; Rats; Species Specificity; Stereoisomerism | 2013 |
Direct high-performance liquid chromatographic enantioseparation of free α-, β- and γ-aminophosphonic acids employing cinchona-based chiral zwitterionic ion exchangers.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cinchona; Ion Exchange Resins; Phosphorous Acids; Quinidine; Quinine; Stereoisomerism | 2013 |
Enantioseparation of 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate tagged amino acids and other zwitterionic compounds on cinchona-based chiral stationary phases.
Topics: Amino Acids; Aminoquinolines; Carbamates; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cinchona; Fluorescence; Quinidine; Quinine; Stereoisomerism | 2013 |
Antimalarial efficacy of hydroxyethylapoquinine (SN-119) and its derivatives.
Topics: Animals; Antimalarials; CHO Cells; Cricetulus; Drug Resistance; ERG1 Potassium Channel; Erythrocytes; Ether-A-Go-Go Potassium Channels; Gene Expression; Humans; Inhibitory Concentration 50; Malaria; Mice; Mice, Inbred C57BL; Plasmodium berghei; Plasmodium falciparum; Quinidine; Quinine; Survival Analysis | 2014 |
Preliminary study of quinine pharmacokinetics in pregnant women with malaria-HIV co-infection.
Topics: Adult; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Coinfection; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria, Falciparum; Nevirapine; Parasite Load; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Quinidine; Quinine; Stavudine; Treatment Outcome; Young Adult; Zidovudine | 2014 |
Differential effects of bitter compounds on the taste transduction channels TRPM5 and IP3 receptor type 3.
Topics: Animals; Calcium; HEK293 Cells; Humans; Inositol 1,4,5-Trisphosphate Receptors; Mice; Nicotine; Patch-Clamp Techniques; Protein Isoforms; Quinidine; Quinine; Signal Transduction; Sweetening Agents; TRPM Cation Channels | 2014 |
Novel chiral stationary phases based on peptoid combining a quinine/quinidine moiety through a C9-position carbamate group.
Topics: Carbamates; Chromatography, High Pressure Liquid; Molecular Structure; Peptoids; Quinidine; Quinine | 2014 |
Enantioseparation of β(2)-amino acids on cinchona alkaloid-based zwitterionic chiral stationary phases. Structural and temperature effects.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Quinidine; Quinine; Stereoisomerism; Temperature; Thermodynamics | 2014 |
Novel carbamoyl type quinine and quinidine based chiral anion exchangers implementing alkyne-azide cycloaddition immobilization chemistry.
Topics: Alkynes; Amino Acids; Azides; Carbamates; Chromatography; Click Chemistry; Cycloaddition Reaction; Ion Exchange; Quinidine; Quinine; Silicon Dioxide; Stereoisomerism | 2014 |
New insight into the stereoselective interactions of quinine and quinidine, with bovine serum albumin.
Topics: Animals; Binding Sites; Cattle; Protein Binding; Protein Structure, Secondary; Quinidine; Quinine; Serum Albumin, Bovine | 2014 |
A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum.
Topics: Animals; Chromosome Mapping; Endoplasmic Reticulum; Golgi Apparatus; Plasmodium falciparum; Polymorphism, Genetic; Quantitative Trait Loci; Quinidine; Quinine; Ubiquitin-Protein Ligases | 2014 |
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites.
Topics: Animals; Antimalarials; Binding Sites; Binding, Competitive; Biological Transport; Cells, Cultured; Chloroquine; Drug Resistance; Female; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Quinidine; Quinine; Verapamil; Xenopus laevis | 2014 |
Macromolecular crowding-assisted fabrication of liquid-crystalline imprinted polymers.
Topics: Acetonitriles; Chemistry Techniques, Synthetic; Chromatography, High Pressure Liquid; Cinchona Alkaloids; Cross-Linking Reagents; Hydrogen-Ion Concentration; Liquid Crystals; Molecular Imprinting; Polymethyl Methacrylate; Polystyrenes; Quinidine; Quinine; Temperature | 2015 |
Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium.
Topics: Animals; Barium; Female; Large-Conductance Calcium-Activated Potassium Channels; Mice; Potassium Channel Blockers; Protein Structure, Secondary; Quinidine; Quinine; Xenopus laevis | 2015 |
Alkoxide coordination of iron(III) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution.
Topics: Acetonitriles; Antimalarials; Cinchona Alkaloids; Coordination Complexes; Ferric Compounds; Mefloquine; Protoporphyrins; Quinidine; Quinine; Spectrophotometry; Thermodynamics; X-Ray Diffraction | 2015 |
Composition of the endophytic filamentous fungi associated with Cinchona ledgeriana seeds and production of Cinchona alkaloids.
Topics: Ascomycota; Base Sequence; Cinchona; Cinchona Alkaloids; Endophytes; Indonesia; Phylogeny; Quinidine; Quinine; Seeds; Species Specificity | 2016 |
Chiral separation of 2-hydroxyglutaric acid on cinchonan carbamate based weak chiral anion exchangers by high-performance liquid chromatography.
Topics: Anions; Carbamates; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Cinchona; Glutarates; Quinidine; Quinine; Stereoisomerism; Temperature | 2016 |
Rescuing artemisinin combination therapy in Africa.
Topics: Africa; Antimalarials; Artemisinins; Clindamycin; Quinidine; Quinine | 2017 |
Chiral separation of short chain aliphatic hydroxycarboxylic acids on cinchonan carbamate-based weak chiral anion exchangers and zwitterionic chiral ion exchangers.
Topics: 3-Hydroxybutyric Acid; Anion Exchange Resins; Carbamates; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fatty Acids; Hydroxy Acids; Ion Exchange Resins; Quinidine; Quinine; Stereoisomerism | 2017 |
Intramolecular Hydrogen Bonds in Conformers of Quinine and Quinidine: An HF, MP2 and DFT Study.
Topics: Antimalarials; Drug Stability; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Quantum Theory; Quinidine; Quinine | 2017 |
Effect of genetic polymorphism on the inhibition of dopamine formation from p-tyramine catalyzed by brain cytochrome P450 2D6.
Topics: Animals; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dopamine; Humans; Polymorphism, Genetic; Quinidine; Quinine; Rats; Recombinant Proteins; Tyramine | 2017 |
Analysis of Species-Selectivity of Human, Mouse and Rat Cytochrome P450 1A and 2B Subfamily Enzymes using Molecular Modeling, Docking and Dynamics Simulations.
Topics: Animals; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Humans; Hydrogen Bonding; Ligands; Mice; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Quinidine; Quinine; Rats; Software; Species Specificity | 2018 |
Reactions of hexadehydro-Diels-Alder benzynes with structurally complex multifunctional natural products.
Topics: Benzene Derivatives; Biological Products; Cycloaddition Reaction; Molecular Structure; Quinidine; Quinine | 2017 |
Chirality sensing of bioactive compounds with amino alcohol unit via circular dichroism.
Topics: Amino Alcohols; Circular Dichroism; Oseltamivir; Quinidine; Quinine; Stereoisomerism | 2017 |
Quantitative determination of major alkaloids in Cinchona bark by Supercritical Fluid Chromatography.
Topics: Alkaloids; Chromatography, Supercritical Fluid; Cinchona; Cinchona Alkaloids; Limit of Detection; Plant Bark; Plant Extracts; Quinidine; Quinine | 2018 |
Detachment of retinal pigment epithelium in retinopathy due to malaria.
Topics: Antimalarials; Chad; Doxycycline; Erythrocytes; Fluorescein Angiography; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Middle Aged; Prednisone; Quinidine; Quinine; Retinal Detachment; Retinal Hemorrhage; Retinal Pigment Epithelium; Tomography, Optical Coherence; Travel-Related Illness | 2018 |
Severe
Topics: Aged; Agricultural Workers' Diseases; Antiprotozoal Agents; Babesia microti; Babesiosis; Clindamycin; Erythrocyte Transfusion; Humans; Immunocompetence; Male; Multiple Organ Failure; Quinidine; Quinine; Treatment Outcome | 2018 |
Detection of Cutting Agents in Drug-Positive Seized Exhibits within the United States.
Topics: Acetaminophen; Caffeine; Chromatography, Liquid; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Kentucky; Levamisole; Procaine; Quinidine; Quinine; Vermont | 2019 |
Stereoselective separation of underivatized and 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatized amino acids using zwitterionic quinine and quinidine type stationary phases by liquid chromatography-High resolution mass spectrometry.
Topics: Amino Acids; Aminoquinolines; Carbamates; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Cinchona; Quinidine; Quinine; Stereoisomerism; Tandem Mass Spectrometry | 2019 |
Expanded Availability of Intravenous Artesunate for the Treatment of Severe Malaria in the United States.
Topics: Administration, Intravenous; Antimalarials; Artesunate; Centers for Disease Control and Prevention, U.S.; Drug Administration Schedule; Drug Approval; Humans; Malaria, Falciparum; Quinidine; Quinine; United States; United States Food and Drug Administration | 2019 |
Role of P-glycoprotein in the brain disposition of seletalisib: Evaluation of the potential for drug-drug interactions.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Drug Interactions; Enzyme Inhibitors; Female; Humans; LLC-PK1 Cells; Male; Phosphatidylinositol 3-Kinases; Pyridines; Quinidine; Quinine; Quinolines; Rats; Rats, Wistar; Swine | 2020 |
Enantioselective Synthesis of 8-Hydroxyquinoline Derivative, Q134 as a Hypoxic Adaptation Inducing Agent.
Topics: Cell Line, Tumor; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydroxyquinolines; Hypoxia-Inducible Factor 1, alpha Subunit; Membrane Potential, Mitochondrial; Oxidative Stress; Oxyquinoline; Protein Stability; Quinidine; Quinine; Stereoisomerism | 2019 |
Resolution of Vaulted Biaryl Ligands via Borate Esters of Quinine and Quinidine.
Topics: Borates; Esters; Ligands; Quinidine; Quinine | 2020 |
Natural product fragment combination to performance-diverse pseudo-natural products.
Topics: Biological Products; Cheminformatics; Chromones; Drug Discovery; Griseofulvin; Indoles; Morphinans; Quinidine; Quinine; Small Molecule Libraries | 2021 |
Pharmacological characterisation of electrocardiogram J-T
Topics: Animals; DNA-Binding Proteins; Electrocardiography; Flecainide; Guinea Pigs; Long QT Syndrome; Nifedipine; Quinidine; Quinine; Ranolazine; Sotalol; Torsades de Pointes; Verapamil | 2022 |
An in silico-in vitro pipeline for drug cardiotoxicity screening identifies ionic pro-arrhythmia mechanisms.
Topics: Action Potentials; Arrhythmias, Cardiac; Cardiotoxicity; Cisapride; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Ion Channels; Myocytes, Cardiac; Quinidine; Quinine; Verapamil | 2022 |
In-silico Investigations of quinine and quinidine as potential Inhibitors of AKR1B1 and AKR1B10: Functional and structural characterization.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Colonic Neoplasms; Humans; Molecular Docking Simulation; Quinidine; Quinine | 2022 |