Page last updated: 2024-08-17

quinidine and quercetin

quinidine has been researched along with quercetin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (38.89)29.6817
2010's10 (55.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Afzelius, L; Andersson, TB; Baroni, M; Cruciani, G; Karlén, A; Masimirembwa, CM; Mecucci, S; Zamora, I1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Hashizume, H; Kawasaki, M; Komatsu, M; Matsumoto, M; Sasaki, H; Shimokawa, Y; Tomishige, T; Tsubouchi, H1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Li, H; Martásek, P; Poulos, TL; Qin, Y; Roman, LJ; Silverman, RB; Wang, HY1
Caligari, S; Callegari, E; De Toma, C; Dilernia, R; Frigerio, F; Graziani, D; Longhi, M; Menegon, S; Pinzi, L; Pirona, L; Rastelli, G; Riva, C; Tazzari, V; Valsecchi, AE; Vistoli, G1
Adebesin, AM; Falck, JR; Fischer, R; Konkel, A; Lossie, J; Paudyal, MP; Puli, N; Schunck, WH; Vijaykumar, J; Wesser, T; Westphal, C; Zhu, C1
Chen, Y; Dong, R; Hou, S; Huang, J; Li, H; Liu, C; Liu, X; Lu, T; Tang, W; Wang, X; Xu, J; Zhang, T; Zhang, Y1
Annaert, PP; Brouwer, KL1
Kanamaru, H; Kitamura, A; Komuro, S; Mizuno, Y; Natsui, K; Yabuki, M1
Kamishikiryo, J; Matsumura, R; Sugihara, N; Takamori, T1
Endo, T; Fujii, Y; Haraguchi, K; Kato, Y; Kimura, O; Koga, N; Ohta, C1

Other Studies

18 other study(ies) available for quinidine and quercetin

ArticleYear
Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors.
    Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4

    Topics: Amino Acids; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Structure; Quantitative Structure-Activity Relationship

2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
    PLoS medicine, 2006, Volume: 3, Issue:11

    Topics: Animals; Antitubercular Agents; Blood; Cell Line; Humans; In Vitro Techniques; Intracellular Membranes; Macrophages; Mammals; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium; Mycobacterium bovis; Mycolic Acids; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis

2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.
    Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10

    Topics: Aminopyridines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Molecular Structure; Nitric Oxide Synthase Type I; Structure-Activity Relationship

2016
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Allosteric Regulation; Amides; Animals; Biological Availability; Carbamates; CHO Cells; Cricetulus; Dogs; Excitatory Amino Acid Agents; Humans; Ligands; Rats; Receptor, Metabotropic Glutamate 5; Structure-Activity Relationship; Sulfonamides; Urea

2019
Development of Robust 17(
    Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22

    Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Dose-Response Relationship, Drug; Drug Stability; Epoxide Hydrolases; Esterification; Hepatocytes; Humans; Male; Mice; Microsomes, Liver; Myocardial Infarction; Myocytes, Cardiac; Rats, Sprague-Dawley; Rats, Wistar

2019
Discovery of
    Journal of medicinal chemistry, 2021, 09-09, Volume: 64, Issue:17

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Catalytic Domain; Cell Line, Tumor; Cyclin-Dependent Kinase 9; Half-Life; Humans; Mice; Molecular Structure; Protein Binding; Protein Kinase Inhibitors; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2021
Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Culture Techniques; Cells, Cultured; Collagenases; Digoxin; Drug Interactions; Hepatocytes; Male; Progesterone; Quercetin; Quinidine; Rats; Rats, Wistar; Rhodamine 123; Verapamil

2005
Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.
    Biopharmaceutics & drug disposition, 2005, Volume: 26, Issue:2

    Topics: Antibodies, Monoclonal; Antipsychotic Agents; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Indoles; Isoenzymes; Isoindoles; Ketoconazole; Male; Microsomes, Liver; Models, Chemical; Quercetin; Quinidine; Thiazoles

2005
Effect of quercetin on the transport of N-acetyl 5-aminosalicylic acid.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:7

    Topics: Aminosalicylic Acids; Biological Transport; Caco-2 Cells; Drug Interactions; Humans; Mitoxantrone; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Propionates; Quercetin; Quinidine; Quinolines

2013
Effect of quercetin on the uptake and efflux of aristolochic acid I from Caco-2 cell monolayers.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:7

    Topics: Acetic Acid; Aristolochic Acids; ATP-Binding Cassette Transporters; Benzoic Acid; Biological Transport; Caco-2 Cells; Cells, Cultured; Cyclosporine; Diketopiperazines; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrogen-Ion Concentration; Indomethacin; Intestinal Absorption; Mitoxantrone; Pravastatin; Propionates; Quercetin; Quinidine; Quinolines

2016