Page last updated: 2024-08-17

quinidine and probenecid

quinidine has been researched along with probenecid in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (9.76)	18.7374
1990's	5 (12.20)	18.2507
2000's	18 (43.90)	29.6817
2010's	13 (31.71)	24.3611
2020's	1 (2.44)	2.80

Authors

Authors	Studies
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Topliss, JG; Yoshida, F	1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T	1
Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL	1
Akhoundova, A; Arndt, P; Bamberg, E; Budiman, T; Gorboulev, V; Koepsell, H; Koppatz, S; Nagel, G; Popp, C; Ulzheimer-Teuber, I; Volk, C	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ebner, T; Ishiguro, N; Kishimoto, W; Schaefer, O; Shimizu, H	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Henderson, GB	1
Hedman, A	1
Bentur, Y; Cheung, D; Klein, J; Koren, G; Moselhy, G	1
Kunnemann, ME; McKinney, TD	1
Holmes, J; Sapeika, N; Zwarenstein, H	1
McKinney, TD; Speeg, KV	1
Offerhaus, L	1
Inui, K; Nakamura, T; Takano, M; Yasuhara, M	1
Hanada, K; Kato, T; Kinami, J; Ogata, H; Takubo, T	1
Bungay, PM; Elmquist, WF; Sun, H	1
Borg, N; Lindén, K; Ljungdahl-Ståhle, E; Ståhle, L	1
Tsai, PL; Tsai, TH	1
Geisslinger, G; Jarrar, M; Langer, M; Lötsch, J; Schmidt, H; Skarke, C	1
Bruesewitz, C; Funke, A; Kuhland, U; Lipp, R; Wagner, T	1
Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Liu, PQ; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW	1
Abaut, AY; Chevanne, F; Le Corre, P	1
Lai, PC; Walters, JD	1
Jung, JA; Parvez, MM; Shin, HJ; Shin, JG	1

Reviews

3 review(s) available for quinidine and probenecid

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug interactions at excretory mechanisms. Pharmacology & therapeutics, 1981, Volume: 15, Issue:1 Topics: Cardiac Glycosides; Drug Interactions; Furosemide; Humans; Hydrogen-Ion Concentration; Kidney Tubules; Lithium; Probenecid; Quinidine; Spironolactone	1981

Trials

1 trial(s) available for quinidine and probenecid

Article	Year
Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans. Anesthesiology, 2004, Volume: 101, Issue:6 Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Membrane Transport Proteins; Models, Biological; Morphine Derivatives; Probenecid; Pupil; Quinidine; Renal Agents	2004

Other Studies

37 other study(ies) available for quinidine and probenecid

Article	Year
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Molecular pharmacology, 2001, Volume: 59, Issue:5 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis	2001
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells. Pharmaceutical research, 2001, Volume: 18, Issue:2 Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium	2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:3 Topics: Animals; Anions; Carrier Proteins; Cations; Cell Line; Cell Membrane; Choline; Cloning, Molecular; Female; Guanidine; Histamine; Humans; In Vitro Techniques; Kidney; Kinetics; Membrane Potentials; Membrane Proteins; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Transfection; Xenopus laevis	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Base Sequence; Dipeptidyl-Peptidase IV Inhibitors; DNA Primers; Drug Evaluation, Preclinical; Drug Interactions; HEK293 Cells; Humans; In Vitro Techniques; Linagliptin; LLC-PK1 Cells; Purines; Quinazolines; Swine	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells. Biochimica et biophysica acta, 1992, Oct-05, Volume: 1110, Issue:2 Topics: Adenosine Triphosphate; Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Leukemia L1210; Methotrexate; Mice; Probenecid; Prostaglandins A; Quinidine; Reserpine; Sulfobromophthalein; Tumor Cells, Cultured; Verapamil; Vincristine	1992
Inhibition by basic drugs of digoxin secretion into human bile. European journal of clinical pharmacology, 1992, Volume: 42, Issue:4 Topics: Bile; Chromatography, High Pressure Liquid; Digoxin; Drug Interactions; Humans; Probenecid; Quinidine; Quinine; Radioimmunoassay; Spironolactone; Verapamil	1992
Renal handling of cisplatin: interactions with organic anions and cations in the dog. Clinical and investigative medicine. Medecine clinique et experimentale, 1991, Volume: 14, Issue:5 Topics: Animals; Anions; Blood Proteins; Cations; Cimetidine; Cisplatin; Dogs; Glomerular Filtration Rate; Kidney; Kidney Tubules; Metabolic Clearance Rate; Probenecid; Protein Binding; Quinidine; Ranitidine	1991
Cimetidine transport in rabbit renal cortical brush-border membrane vesicles. The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2 Topics: Animals; Biological Transport, Active; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cimetidine; Female; Hydrogen-Ion Concentration; Kidney Cortex; Microvilli; Osmolar Concentration; Probenecid; Procainamide; Quinidine; Rabbits; Tetraethylammonium Compounds; Valinomycin	1987
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro. Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2 Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts	1973
Cimetidine and procainamide secretion by proximal tubules in vitro. The American journal of physiology, 1982, Volume: 242, Issue:6 Topics: Absorption; Acecainide; Animals; Carbon Dioxide; Chromatography, High Pressure Liquid; Cimetidine; Guanidines; Hypothermia; Kidney Tubules, Proximal; Kinetics; Ouabain; Probenecid; Procainamide; Quinidine; Rabbits	1982
In-vivo clearance study of vancomycin in rats. The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:11 Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Cimetidine; Kidney; Male; Metabolic Clearance Rate; Probenecid; Quinidine; Rats; Rats, Wistar; Renal Agents; Vancomycin	1996
Effect of trimethoprim on the renal clearance of lamivudine in rats. The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:3 Topics: Animals; Anti-HIV Agents; Cimetidine; Drug Interactions; Glomerular Filtration Rate; Kidney; Lamivudine; Male; Metabolic Clearance Rate; Probenecid; Quinidine; Rats; Rats, Wistar; Time Factors; Trimethoprim	2000
Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3 Topics: Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Capillary Permeability; Carrier Proteins; Cross-Over Studies; Dibenzocycloheptenes; Fluoresceins; Fluorescent Dyes; Frontal Lobe; Male; Microdialysis; Models, Biological; Probenecid; Quinidine; Quinolines; Rats; Rats, Wistar; Sensitivity and Specificity; Time Factors	2001
Effect of probenecid and quinidine on the transport of alovudine (3'-fluorothymidine) to the rat brain studied by microdialysis. Pharmacology & toxicology, 2003, Volume: 93, Issue:5 Topics: Animals; Antiviral Agents; Area Under Curve; Biological Transport, Active; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Dideoxynucleosides; Extracellular Fluid; Male; Microdialysis; Probenecid; Quinidine; Rats; Rats, Sprague-Dawley; Tissue Distribution	2003
Hepatobiliary excretion of berberine. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4 Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Berberine; Bile; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Glucuronides; Half-Life; Injections, Intravenous; Liver; Male; Methylation; Microdialysis; Organic Cation Transport Proteins; Proadifen; Probenecid; Quinidine; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Time Factors	2004
Comparison of permeation enhancing strategies for an oral factor Xa inhibitor using the Caco-2 cell monolayer model. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2006, Volume: 64, Issue:2 Topics: Algorithms; Antithrombin III; Caco-2 Cells; Cell Membrane Permeability; Chitosan; Drug Synergism; Glycerides; Humans; Molecular Structure; Probenecid; Prodrugs; Quinidine; Serine Proteinase Inhibitors; Spectrophotometry, Ultraviolet; Verapamil	2006
Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge. Current drug metabolism, 2007, Volume: 8, Issue:4 Topics: Abietanes; Adenosine Triphosphate; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Digoxin; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Microsomes, Liver; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Probenecid; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Temperature; Transfection; Verapamil	2007
Influence of efflux transporters on liver, bile and brain disposition of amitriptyline in mice. International journal of pharmaceutics, 2009, Aug-13, Volume: 378, Issue:1-2 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Brain; Cytochrome P-450 CYP2D6; Female; Injections, Intraperitoneal; Liver; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Novobiocin; Probenecid; Quinidine; Tissue Distribution	2009
Azithromycin kills invasive Aggregatibacter actinomycetemcomitans in gingival epithelial cells. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3 Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Azithromycin; Biological Transport; Carnitine; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Gingiva; Humans; Kinetics; Probenecid; Procainamide; Pyrilamine; Quinidine; Time Factors	2013
Evaluation of Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:5 Topics: Aminosalicylic Acid; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cimetidine; Drug Interactions; HEK293 Cells; Humans; Ibuprofen; Liver-Specific Organic Anion Transporter 1; Naproxen; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 2; Probenecid; Proton Pump Inhibitors; Quinidine; Rifampin; Verapamil	2017