Page last updated: 2024-08-17

quinidine and pentobarbital

quinidine has been researched along with pentobarbital in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199014 (56.00)18.7374
1990's2 (8.00)18.2507
2000's5 (20.00)29.6817
2010's4 (16.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bedoya, M; Decher, N; González, W; Kiper, AK; Ramírez, D; Rinné, S1
Romankiewicz, JA1
Chapron, DJ; Mumford, D; Pitegoff, GI1
Gallagher, JD1
Boucher, M; Dubray, C; Duchêne-Marullaz, P; Li, JH; Paire, M1
Devine, JE1
Heeg, E; Reuter, N1
Kritcher, EM; Luchi, RJ1
Foulks, JG; Perry, FA; Sanders, HD1
Foulks, JG; Miller, JA; Perry, FA1
Reuter, N1
Boulos, BM; Davis, LE; Short, CR1
Blackmore, DJ; Curry, AS; Hayes, TS; Rutter, ER1
Pruett, JK; Woods, EF1
DiGregorio, GJ; Fruncillo, RJ1
Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M1
Airarat, W; Cha-on, U; Kukongviriyapan, U; Kukongviriyapan, V; Simajareuk, S1
BEUTNER, R; CALESNICK, B; SMITH, NH1

Reviews

2 review(s) available for quinidine and pentobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
TASK Channels Pharmacology: New Challenges in Drug Design.
    Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22

    Topics: Animals; Drug Design; Drug Discovery; Humans; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Tandem Pore Domain

2019

Other Studies

23 other study(ies) available for quinidine and pentobarbital

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
Effects of antacids on gastrointestinal absorption of drugs.
    Primary care, 1976, Volume: 3, Issue:3

    Topics: Animals; Antacids; Aspirin; Chlordiazepoxide; Chlorpromazine; Dicumarol; Digitoxin; Digoxin; Ephedrine; Guinea Pigs; Humans; Intestinal Absorption; Iron; Isoniazid; Levodopa; Naproxen; Pentobarbital; Pharmaceutical Preparations; Quinidine; Quinine; Rats; Sulfadiazine; Tetracyclines; Warfarin

1976
Apparent quinidine-induced digoxin toxicity after withdrawal of pentobarbital: a case of sequential drug interactions.
    Archives of internal medicine, 1979, Volume: 139, Issue:3

    Topics: Aged; Atrial Fibrillation; Digoxin; Drug Interactions; Female; Half-Life; Humans; Liver; Pentobarbital; Quinidine; Sleep Wake Disorders

1979
Effects of halothane and quinidine on intracardiac conduction and QTc interval in pentobarbital-anesthetized dogs.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:5

    Topics: Action Potentials; Anesthesia; Animals; Dogs; Electrocardiography; Halothane; Heart Conduction System; Hemodynamics; Pentobarbital; Purkinje Fibers; Quinidine

1992
Influence of pentobarbital and chloralose anesthesia on quinidine-induced effects on atrial refractoriness and heart rate in the dog.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:2

    Topics: Anesthetics; Animals; Atrial Function; Blood Pressure; Chloralose; Dogs; Drug Interactions; Female; Heart Rate; Male; Pentobarbital; Quinidine; Ventricular Function

1991
Assessment of the Corvac blood collection tube for drug specimen processing.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:2

    Topics: Blood Specimen Collection; Humans; Lidocaine; Pentobarbital; Pharmaceutical Preparations; Phenytoin; Quinidine; Theophylline; Time Factors

1986
[Effect of ajmaline, N-propyl-ajmaline and quinidine on heart and blood circulation in anesthetized cats].
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 272, Issue:3

    Topics: Ajmaline; Animals; Blood Pressure; Cats; Computers; Computers, Analog; Electrocardiography; Female; Glucagon; Heart; Heart Rate; Lethal Dose 50; Male; Pentobarbital; Plants, Medicinal; Quinidine; Rauwolfia

1972
Drug effects on cardiac myosin adenosine triphosphatase activity.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensin II; Animals; Binding Sites; Calcium; Chloralose; Cyclopropanes; Digoxin; Dogs; Epinephrine; Ethers; Heart; Heart Failure; In Vitro Techniques; Isoproterenol; Lidocaine; Magnesium; Muscle Contraction; Muscle Proteins; Myocardium; Nitrous Oxide; Norepinephrine; Ouabain; Pentobarbital; Pharmacology; Procainamide; Protein Binding; Quinidine; Secobarbital

1967
Augmentation of caffeine-contracture tension by twitch-potentiating agents in frog toe muscle.
    Canadian journal of physiology and pharmacology, 1971, Volume: 49, Issue:10

    Topics: Androstanes; Animals; Anura; Caffeine; Calcium; Cell Membrane; Chloroform; Drug Interactions; Drug Synergism; Ethers; In Vitro Techniques; Magnesium; Membrane Potentials; Muscle Contraction; Neuromuscular Depolarizing Agents; Nitrates; Pentobarbital; Perchlorates; Potassium; Quinidine; Tetraethylammonium Compounds; Toes; Zinc

1971
Restoration of the ability of frog skeletal muscle to develop potassium contractures in calcium-deficient media.
    Canadian journal of physiology and pharmacology, 1973, Volume: 51, Issue:5

    Topics: Acetates; Androstanes; Animals; Anura; Caffeine; Calcium; Chelating Agents; Chlorides; Ethyl Ethers; Ferrocyanides; Glycols; In Vitro Techniques; Kinetics; Magnesium; Muscle Contraction; Muscles; Nitrates; Pentobarbital; Potassium; Quinidine; Tetraethylammonium Compounds; Time Factors; Zinc

1973
[Effect of quinidine, iproveratril, lidocaine and sparteine on ECG and circulatory system of the anesthetized cat].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:8

    Topics: Anesthesia; Animals; Blood Pressure; Cats; Drug Interactions; Electrocardiography; Heart; Heart Rate; Hemodynamics; Injections, Intraperitoneal; Lidocaine; Male; Pentobarbital; Quinidine; Sinoatrial Node; Sparteine; Verapamil

1973
Quinine and quinidine inhibition of pentobarbital metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:3

    Topics: Animals; Arousal; Blood Proteins; Brain Chemistry; Carbon Isotopes; Goats; Horses; Humans; In Vitro Techniques; Mice; Microsomes, Liver; Pentobarbital; Protein Binding; Quinidine; Quinine; Rats; Sleep; Species Specificity; Swine; Time Factors

1970
Automated analysis for drugs in urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Alkaloids; Amobarbital; Autoanalysis; Barbiturates; Chemistry, Clinical; Chlordiazepoxide; Fluorometry; Humans; Indicators and Reagents; Male; Methods; Morphine; Nicotine; Pentobarbital; Quinidine; Smoking; Spectrophotometry; Ultraviolet Rays

1971
The relationship of intracellular depolarization rates and contractility in the dog ventricle in situ: effects of positive and negative inotropic agents.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1

    Topics: Action Potentials; Animals; Cocaine; Digoxin; Dogs; Electrophysiology; Female; Heart; Heart Ventricles; Male; Muscle Contraction; Pentobarbital; Quinidine

1967
Pharmacokinetics of pentobarbital, quinidine, lidocaine, and theophylline in the thermally injured rat.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:8

    Topics: Animals; Burns; Dialysis; Kinetics; Lidocaine; Male; Pentobarbital; Quinidine; Rats; Rats, Inbred Strains; Theophylline

1984
Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:1

    Topics: Acute Disease; Anesthesia; Anesthetics, Inhalation; Animals; Astemizole; Atrioventricular Node; Catheter Ablation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Electrocardiography; Female; Halothane; Heart Block; Isoflurane; Long QT Syndrome; Male; Pentobarbital; Quinidine; Sensitivity and Specificity; Torsades de Pointes

2001
Alteration of drug kinetics in rats following exposure to trichloroethylene.
    Pharmacology, 2001, Volume: 63, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Hypnotics and Sedatives; Male; Pentobarbital; Pharmacokinetics; Phosphodiesterase Inhibitors; Quinidine; Rats; Rats, Sprague-Dawley; Sex Factors; Solvents; Theophylline; Trichloroethylene

2001
Combined action of cardiotoxic drugs; a study on the acute toxicity of combined quinidine, meperidine, pentobarbital, procaine and procaine amide.
    The Journal of pharmacology and experimental therapeutics, 1951, Volume: 102, Issue:2

    Topics: Cardiotoxicity; Heart; Hedera; Meperidine; Pentobarbital; Procainamide; Procaine; Quinidine

1951