Page last updated: 2024-08-17

quinidine and morphine

quinidine has been researched along with morphine in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199016 (30.19)18.7374
1990's4 (7.55)18.2507
2000's22 (41.51)29.6817
2010's11 (20.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Dagenais, C; Ducharme, J; Pollack, GM; Zong, J1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A1
Thakker, DR; Troutman, MD1
Nagashima, R; Nishikawa, T; Tobita, M1
Jolivette, LJ; Ward, KW1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gibson, TC1
Angelo, HR; Arendt-Nielsen, L; Bjerring, P; Brøsen, K; Eriksen, B; Gram, LF; Sindrup, SH1
Agon, P; Bogaert, MG; Goethals, P; Kaufman, JM; Van Haver, D1
Ivanova, TN; Pavlova, LT1
Almirante, L; Murmann, W; Saccani-Guelfi, M1
Beattie, JM; Demetriou, JA; Lowe, ML; Weissman, N1
Blackmore, DJ; Curry, AS; Hayes, TS; Rutter, ER1
Brochmann-Hanssen, E; Fontan, CR1
Stone, TW1
Bochner, F; Eichelbaum, M; Horak, P; Mikus, G; Somogyi, AA; Spector, S1
Asmussen, J; Broen Christensen, C; Brøsen, K; Hofmann, U; Ingwersen, SH; Mikus, G; Nielsen, F; Sindrup, SH1
Caraco, Y; Sheller, J; Wood, AJ1
FORTIN, P1
GIULIANI, G1
ROCHEMAURE, J1
DEXTER, L; PIEMME, TE1
MACKENZIE, GJ; PASCUAL, S1
PESTEL, M1
Erb, K; Geisslinger, G; Jarrar, M; Lötsch, J; Schmidt, H; Skarke, C1
Hoffer, C; Kharasch, ED; Sheffels, P; Whittington, D1
ESTANDIA, A; FORD, TJ; HARRIS, AS; TILLOTSON, RF1
Cisternino, S; Debray, M; Rousselle, C; Scherrmann, JM1
Bianchi, E; Cadet, P; Esch, T; Goumon, Y; Mantione, KJ; Shen, L; Sonetti, D; Stefano, GB; Zhu, W1
Raffa, RB; Stone, DJ1
Bisaga, A; Daniel, WA; Kos, T; Popik, P; Wójcikowski, J1
Ito, Y; Kagawa, Y; Kimura, M; Okura, T; Ozawa, T; Yamada, S1
Ito, Y; Kagawa, Y; Morita, Y; Okura, T; Yamada, S1
Capasso, A; Gallo, C1
Iwanaga, K; Kakemi, M; Minamida, M; Miyazaki, M; Nishimura, C1
Al-Huniti, N; Bui, K; Butler, K; She, F; Sostek, M; Zhou, D1

Reviews

2 review(s) available for quinidine and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The heart in myasthenia gravis.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography

1975

Trials

6 trial(s) available for quinidine and morphine

ArticleYear
The effect of quinidine on the analgesic effect of codeine.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:6

    Topics: Adult; Codeine; Double-Blind Method; Drug Interactions; Female; Humans; Male; Morphine; Pain Measurement; Quinidine

1992
Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake.
    European journal of clinical pharmacology, 1996, Volume: 49, Issue:6

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Blood-Brain Barrier; Central Nervous System; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Methylation; Middle Aged; Mixed Function Oxygenases; Morphine; Quinidine; Sparteine

1996
Impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1

    Topics: Adult; Analgesics, Opioid; Asian People; Biotransformation; Codeine; Cross-Over Studies; Dealkylation; Debrisoquin; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Female; Humans; Male; Morphine; Psychomotor Performance; Pupil; Quinidine; Respiratory Mechanics; White People

1999
Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine.
    Clinical pharmacology and therapeutics, 2003, Volume: 74, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Humans; Infusions, Intravenous; Male; Miosis; Morphine; Pain Measurement; Quinidine; Respiration

2003
Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine.
    Clinical pharmacology and therapeutics, 2003, Volume: 74, Issue:6

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Analgesics, Opioid; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Half-Life; Humans; Injections, Intravenous; Intestinal Absorption; Male; Metabolic Clearance Rate; Morphine; Quinidine

2003
The effect of quinidine, a strong P-glycoprotein inhibitor, on the pharmacokinetics and central nervous system distribution of naloxegol.
    Journal of clinical pharmacology, 2016, Volume: 56, Issue:4

    Topics: Adult; Analgesics, Opioid; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Central Nervous System; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Morphinans; Morphine; Pain; Polyethylene Glycols; Quinidine; Receptors, Opioid, mu

2016

Other Studies

45 other study(ies) available for quinidine and morphine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Effect of mdr1a P-glycoprotein gene disruption, gender, and substrate concentration on brain uptake of selected compounds.
    Pharmaceutical research, 2001, Volume: 18, Issue:7

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Knockout; Morphine; Narcotics; Perfusion; Quinidine; Sex Characteristics; Substrate Specificity; Verapamil

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
    Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine

2003
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
    Pharmaceutical research, 2003, Volume: 20, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Study with positron emission tomography of the osmotic opening of the dog blood-brain barrier for quinidine and morphine.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:8

    Topics: Animals; Blood-Brain Barrier; Brain; Dogs; Evans Blue; Mannitol; Morphine; Osmosis; Quinidine; Tomography, Emission-Computed

1988
[Correction of arrhythmia in the complex treatment of cardiac insufficiency and heart defects].
    Kardiologiia, 1970, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Flutter; Cardiac Complexes, Premature; Electric Countershock; Female; Heart Failure; Heart Valve Diseases; Humans; Middle Aged; Morphine; Phenylephrine; Procainamide; Quinidine; Sodium Chloride; Strophanthins; Tachycardia

1970
Effects of hexobarbitone, ether, morphine, and urethane upon the acute toxicity of propranolol and D-(--)-INPEA.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:10

    Topics: Amino Alcohols; Animals; Atropine; Bradycardia; Central Nervous System; Drug Synergism; Ethers; Heart Arrest; Heart Rate; Hexobarbital; Lidocaine; Male; Mice; Morphine; Nitrobenzenes; Propranolol; Quinidine; Seizures; Sleep; Urethane

1966
Screening method for detection of drugs of abuse in human urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Alkaloids; Amphetamine; Analgesics; Barbiturates; Chlorpheniramine; Chromatography; Chromatography, Thin Layer; Codeine; Dextropropoxyphene; Histamine H1 Antagonists; Hot Temperature; Humans; Indicators and Reagents; Isonipecotic Acids; Meperidine; Methadone; Methods; Morphinans; Morphine; Pentazocine; Phenacetin; Phenothiazines; Quinidine; Substance-Related Disorders; Ultraviolet Rays

1971
Automated analysis for drugs in urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Alkaloids; Amobarbital; Autoanalysis; Barbiturates; Chemistry, Clinical; Chlordiazepoxide; Fluorometry; Humans; Indicators and Reagents; Male; Methods; Morphine; Nicotine; Pentobarbital; Quinidine; Smoking; Spectrophotometry; Ultraviolet Rays

1971
Gas chromatography of alkaloids with polar stationary liquids.
    Journal of chromatography, 1965, Volume: 19, Issue:2

    Topics: Alkaloids; Atropine; Chromatography, Gas; Cinchona; Cocaine; Codeine; Morphine; Papaverine; Pilocarpine; Plants, Medicinal; Quinidine; Quinine; Scopolamine; Strychnine; Thebaine

1965
The effects of 4-aminopyridine on the isolated vas deferens and its effects on the inhibitory properties of adenosine, morphine, noradrenaline and gamma-aminobutyric acid.
    British journal of pharmacology, 1981, Volume: 73, Issue:3

    Topics: 4-Aminopyridine; Adenosine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Morphine; Muscle Contraction; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium Chloride; Quinidine; Tetraethylammonium Compounds; Vas Deferens

1981
Endogenous codeine and morphine in poor and extensive metabolisers of the CYP2D6 (debrisoquine/sparteine) polymorphism.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2

    Topics: Adult; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Morphine; Phenotype; Polymorphism, Genetic; Quinidine

1994
[VENTRICULAR TACHYCARDIA. (DIAGNOSIS AND TREATMENT)].
    Les Cahiers du College de medecine des hopitaux de Paris, 1963, Dec-30, Volume: 4

    Topics: Digitalis Glycosides; Electric Countershock; Electric Stimulation Therapy; Electrocardiography; Hydroxyzine; Morphine; Potassium; Procainamide; Quinidine; Tachycardia; Tachycardia, Ventricular

1963
[TREATMENT OF MYASTHENIA].
    Minerva medica, 1964, Jan-27, Volume: 55

    Topics: Adrenocorticotropic Hormone; Cyclopropanes; Epinephrine; Galantamine; Humans; Hypnotics and Sedatives; Isoflurophate; Morphine; Myasthenia Gravis; Neostigmine; Neuromuscular Nondepolarizing Agents; Nitrogen; Organophosphate Poisoning; Parasympathomimetics; Phosphorus; Poisons; Quinidine; Quinine; Surgical Procedures, Operative; Thymus Gland

1964
[TREATMENT OF PAROXYSMAL TACHYCARDIA].
    Le Progres medical, 1964, May-10, Volume: 92

    Topics: Acetylcholine; Alkaloids; Digitalis Glycosides; Electric Countershock; Electric Stimulation Therapy; Humans; Hydroxyzine; Morphine; Phenylephrine; Procainamide; Quinidine; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal

1964
DISORDERS OF THE PULMONARY CIRCULATION.
    Modern treatment, 1964, Volume: 1

    Topics: Aminophylline; Anti-Bacterial Agents; Antibiotics, Antitubercular; Diagnosis; Diet, Sodium-Restricted; Digitalis Glycosides; Diuretics; Humans; Hyperemia; Hypertension; Hypertension, Pulmonary; Morphine; Oxygen; Procaine; Pulmonary Circulation; Pulmonary Edema; Pulmonary Embolism; Pulmonary Heart Disease; Quinidine; Therapeutics; Vascular Surgical Procedures

1964
PAROXYSMAL VENTRICULAR TACHYCARDIA.
    British heart journal, 1964, Volume: 26

    Topics: Coronary Disease; Diagnosis; Digitalis Glycosides; Electrocardiography; Heart Failure; Hydrocortisone; Morphine; Mortality; Myocardial Infarction; Phenobarbital; Procainamide; Quinidine; Rheumatic Heart Disease; Statistics as Topic; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Ventricular; Toxicology

1964
[WHAT SHOULD BE KNOWN ABOUT AURICULAR PAROXYSMAL TACHYCARDIA AND ITS TREATMENT].
    La Presse medicale, 1965, Apr-24, Volume: 73

    Topics: Acetylcholine; Barbiturates; Child; Diagnosis; Digitalis Glycosides; Drug Therapy; Electrocardiography; Heart Block; Humans; Morphine; Phenylephrine; Potassium; Procainamide; Quinidine; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal; Therapeutics

1965
Quinidine lactate and gluconate in the suppression of ectopic ventricular tachycardias associated with myocardial infarction; control of toxicity by morphine.
    Circulation, 1951, Volume: 4, Issue:4

    Topics: Gluconates; Humans; Lactic Acid; Morphine; Myocardial Infarction; Quinidine; Tachycardia; Tachycardia, Ventricular; Ventricular Premature Complexes

1951
In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier.
    Pharmaceutical research, 2004, Volume: 21, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Colchicine; Cyclosporins; Dexamethasone; Drug Interactions; Male; Mice; Mice, Inbred Strains; Morphine; Progesterone; Quinidine; Verapamil; Vinblastine

2004
Tyrosine and tyramine increase endogenous ganglionic morphine and dopamine levels in vitro and in vivo: cyp2d6 and tyrosine hydroxylase modulation demonstrates a dopamine coupling.
    Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:11

    Topics: alpha-Methyltyrosine; Animals; Base Sequence; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; DNA, Complementary; Dopamine; Enzyme Inhibitors; Ganglia, Invertebrate; Molecular Sequence Data; Morphine; Mytilus edulis; Quinidine; RNA, Messenger; Tyramine; Tyrosine; Tyrosine 3-Monooxygenase; Up-Regulation

2005
Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Analgesics, Opioid; Animals; Codeine; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Hot Temperature; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quinidine; Reserpine; Seizures; Stereoisomerism; Tramadol

2008
Brain levels of dextromethorphan and the intensity of opioid withdrawal in mice.
    Drug and alcohol dependence, 2008, May-01, Volume: 95, Issue:1-2

    Topics: Animals; Brain; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Drug Synergism; Male; Mastication; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Quinidine; Stereotyped Behavior; Substance Withdrawal Syndrome

2008
Enhancement by grapefruit juice of morphine antinociception.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:12

    Topics: Algorithms; Analgesics, Opioid; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beverages; Citrus paradisi; Drug Synergism; Drug Tolerance; Intestinal Absorption; Male; Microdialysis; Morphine; Pain Measurement; Quinidine; Rats; Rats, Sprague-Dawley; Reaction Time

2008
Effects of quinidine on antinociception and pharmacokinetics of morphine in rats.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:5

    Topics: Administration, Oral; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intravenous; Intestinal Absorption; Male; Metabolic Clearance Rate; Morphine; Pain Measurement; Quinidine; Rats; Rats, Sprague-Dawley; Tissue Distribution

2009
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
    Current drug safety, 2009, Volume: 4, Issue:2

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline

2009
Pharmacokinetic assessment of absorptive interaction of oral etoposide and morphine in rats.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:3

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Drug Interactions; Etoposide; Intestinal Absorption; Male; Morphine; Propantheline; Quinidine; Rats; Rats, Wistar

2014