quinidine has been researched along with isomethyleugenol in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beaune, P; Cullin, C; Mansuy, D; Pompon, D; Renaud, JP | 1 |
| Cull, GA; Scott, NC | 1 |
| Charette, C; Midha, KK | 1 |
| Kalsner, S | 2 |
| Bochner, F; Kerry, NL; Mikus, G; Somogyi, AA | 1 |
| Asmussen, J; Broen Christensen, C; Brøsen, K; Hofmann, U; Ingwersen, SH; Mikus, G; Nielsen, F; Sindrup, SH | 1 |
| Juvonen, RO; Kojo, A; Komulainen, H; Liesivuori, J; Pasanen, M; Pennanen, S | 1 |
| Hufschmid, E; Theurillat, R; Thormann, W; Wilder-Smith, CH | 1 |
| Fogelman, SM; Greenblatt, DJ; Schmider, J; Shader, RI; von Moltke, LL | 1 |
| Jones, BC; Smith, DA; Tyman, CA | 1 |
| Belpaire, FM; Brøsen, K; Rasmussen, BB; Temmerman, A; Wijnant, P | 1 |
| Linnet, K; Olesen, OV | 1 |
| Greenblatt, DJ; Shader, RI; Störmer, E; von Moltke, LL | 1 |
| Ekins, S; Mankowski, DC; Margolis, JM; O'Donnell, JP; Obach, RS | 1 |
| Ahokas, JT; Ching, MS; Ghabrial, H; Haritos, VS | 1 |
| Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL | 1 |
| Gillam, EM; Guengerich, FP; Hanna, IH; Martin, MV | 1 |
| Di Marco, A; Laufer, R; Yao, D | 1 |
| Kraemer, T; Maurer, HH; Paul, LD; Springer, D; Staack, RF | 1 |
| Tsai, PL; Tsai, TH | 1 |
| Howald, W; Lalovic, B; Phillips, B; Risler, LL; Shen, DD | 1 |
1 trial(s) available for quinidine and isomethyleugenol
| Article | Year |
|---|---|
Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake.
Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Blood-Brain Barrier; Central Nervous System; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Methylation; Middle Aged; Mixed Function Oxygenases; Morphine; Quinidine; Sparteine | 1996 |
21 other study(ies) available for quinidine and isomethyleugenol
| Article | Year |
|---|---|
Expression of human liver cytochrome P450 IIIA4 in yeast. A functional model for the hepatic enzyme.
Topics: Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Fungal; Humans; Immunohistochemistry; Macrolides; Methylation; Microsomes, Liver; Nifedipine; Oxidation-Reduction; Plasmids; Quinidine; Saccharomyces cerevisiae; Spectrophotometry; Substrate Specificity | 1990 |
Structure-activity relationships in some series of 2-alkyl-1,2,3,-benzotriazinium compounds.
Topics: Acetylcholine; Alkylation; Animals; Anura; Chemical Phenomena; Chemistry; Chickens; In Vitro Techniques; Methylation; Muscle Contraction; Muscles; Quaternary Ammonium Compounds; Quinidine; Rana pipiens; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Triazines; Tubocurarine | 1973 |
GLC determination of quinidine from plasma and whole blood.
Topics: Aniline Compounds; Chromatography, Gas; Cinchona; Humans; Methods; Methylation; Plants, Medicinal; Quinidine; Spectrometry, Fluorescence; Time Factors | 1974 |
Potentiation of responses to histamine in aortic strips by steroids.
Topics: Amine Oxidase (Copper-Containing); Amodiaquine; Animals; Aorta; Drug Synergism; Estradiol; Histamine; Hydrocortisone; Ileum; Imidazoles; Iproniazid; Methylation; Muscle Contraction; Muscle, Smooth; Quinidine; Rabbits; Reserpine; Serotonin; Steroids; Testosterone; Transferases | 1970 |
Effects of tyramine on responses to and inactivation of histamine in aortic strips.
Topics: Amine Oxidase (Copper-Containing); Amodiaquine; Animals; Aorta; Catecholamines; Chlorpheniramine; Cocaine; Diffusion; Histamine; Imidazoles; In Vitro Techniques; Iproniazid; Methylation; Muscle Contraction; Muscles; Oils; Phentolamine; Quinidine; Rabbits; Reserpine; Semicarbazides; Tranylcypromine; Tyramine | 1970 |
The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes.
Topics: Autoantibodies; Binding, Competitive; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextropropoxyphene; Dextrorphan; Humans; In Vitro Techniques; Methadone; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Perhexiline; Phenotype; Quinidine | 1994 |
CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver.
Topics: Aged; Animals; Antibodies, Monoclonal; Caproates; Cytochrome P-450 Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Male; Methylation; Metyrapone; Mice; Microsomes, Liver; Middle Aged; NADPH-Ferrihemoprotein Reductase; Occupational Exposure; Proadifen; Quinidine; Rats; Rats, Wistar; Troleandomycin | 1996 |
Characterization of the genetic polymorphism of dihydrocodeine O-demethylation in man via analysis of urinary dihydrocodeine and dihydromorphine by micellar electrokinetic capillary chromatography.
Topics: Codeine; Dihydromorphine; Electrophoresis, Capillary; Humans; Methylation; Micelles; Phenotype; Polymorphism, Genetic; Quinidine; Reference Values | 1996 |
Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.
Topics: Animals; Antitussive Agents; Benzoflavones; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Ditiocarb; Enzyme Inhibitors; Humans; In Vitro Techniques; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Quinidine; Rats; Sulfaphenazole; Tissue Donors | 1997 |
Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes.
Topics: Adult; Aged; Anisoles; Anti-Infective Agents; Anticoagulants; Antifungal Agents; Antimalarials; Binding, Competitive; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Kinetics; Male; Methylation; Microsomes, Liver; Middle Aged; Quinidine; Substrate Specificity; Sulfaphenazole; Theophylline | 1997 |
The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors.
Topics: 1-Naphthylamine; Adult; Anti-Arrhythmia Agents; Child; Citalopram; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Fluoxetine; Fluvoxamine; Humans; Hydroxylation; Kinetics; Male; Methylation; Metoprolol; Microsomes, Liver; Oxidation-Reduction; Paroxetine; Quinidine; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
Studies on the stereoselective metabolism of citalopram by human liver microsomes and cDNA-expressed cytochrome P450 enzymes.
Topics: Citalopram; Cytochrome P-450 Enzyme System; DNA, Complementary; Fluvoxamine; Gene Expression; Humans; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Oxidation-Reduction; Quinidine; Recombinant Proteins; Stereoisomerism | 1999 |
Metabolism of the antidepressant mirtazapine in vitro: contribution of cytochromes P-450 1A2, 2D6, and 3A4.
Topics: Antidepressive Agents, Tricyclic; Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydroxylation; Isoenzymes; Methylation; Mianserin; Microsomes, Liver; Mirtazapine; Oxidation-Reduction; Quinidine; Recombinant Proteins | 2000 |
(R)-, (S)-, and racemic fluoxetine N-demethylation by human cytochrome P450 enzymes.
Topics: Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Fluoxetine; Humans; Isoenzymes; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Quinidine; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Stereoisomerism; Sulfaphenazole | 2000 |
Role of cytochrome P450 2D6 (CYP2D6) in the stereospecific metabolism of E- and Z-doxepin.
Topics: Cytochrome P-450 CYP2D6; Doxepin; Humans; Hydroxylation; Methylation; Microsomes, Liver; Quinidine; Recombinant Proteins | 2000 |
CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.
Topics: Anti-Anxiety Agents; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flunitrazepam; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Quinidine; Ritonavir; Sulfaphenazole; Transfection | 2001 |
Role of glutamic acid 216 in cytochrome P450 2D6 substrate binding and catalysis.
Topics: Amines; Amino Acid Substitution; Binding Sites; Catalysis; Cytochrome P-450 CYP2D6; Ethanolamines; Glutamic Acid; Glutamine; Humans; Hydroxylation; Methylation; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Binding; Quinidine; Recombinant Proteins; Spiro Compounds; Static Electricity; Substrate Specificity; Sulfonamides; Tyramine | 2003 |
Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.
Topics: Animals; Benzoflavones; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Hepatocytes; Inhibitory Concentration 50; Kinetics; Male; Methylation; Microsomes, Liver; Oxidoreductases, O-Demethylating; Protein Binding; Quinidine; Quinine; Rats; Rats, Sprague-Dawley; Sulfaphenazole; Troleandomycin | 2003 |
Identification of cytochrome P450 enzymes involved in the metabolism of 4'-methoxy-alpha-pyrrolidinopropiophenone (MOPPP), a designer drug, in human liver microsomes.
Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6 Inhibitors; DNA, Complementary; Humans; Kinetics; Liver; Mass Spectrometry; Methylation; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Models, Chemical; Propiophenones; Protein Isoforms; Pyrroles; Pyrrolidines; Quinidine; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2003 |
Hepatobiliary excretion of berberine.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Berberine; Bile; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Glucuronides; Half-Life; Injections, Intravenous; Liver; Male; Methylation; Microdialysis; Organic Cation Transport Proteins; Proadifen; Probenecid; Quinidine; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2004 |
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Intestinal Mucosa; Intestines; Ketoconazole; Kinetics; Metabolic Clearance Rate; Methylation; Microsomes; Microsomes, Liver; Molecular Structure; Morphinans; Oxidoreductases, N-Demethylating; Oxycodone; Oxymorphone; Protein Binding; Quinidine | 2004 |