Page last updated: 2024-08-17

quinidine and hydrochlorothiazide

quinidine has been researched along with hydrochlorothiazide in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19909 (30.00)18.7374
1990's1 (3.33)18.2507
2000's11 (36.67)29.6817
2010's8 (26.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G; Lorenti, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chazov, EI1
Crockatt, D; Okuno, T1
Almeyda, J; Levantine, A1
Crowell, EB; Eisner, EV1
Orgain, ES; Zipes, DP1
Hancock, EW1
AbdelHameed, MH; Chen, TM; Chiou, WL1
HYMAN, AS1
BAKER, DR; HITCHCOCK, CR; SCHRADER, WH1
Kapoor, N; Panchagnula, R; Sarkar, M; Varma, MV1
Panchagnula, R; Varma, MV1

Reviews

2 review(s) available for quinidine and hydrochlorothiazide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug reactions. XVI. Lichenoid drug eruptions.
    The British journal of dermatology, 1971, Volume: 85, Issue:6

    Topics: Aminosalicylic Acids; Aniline Compounds; Arsphenamine; Chlorothiazide; Chlorpropamide; Dermatitis, Exfoliative; Gold; Humans; Hydrochlorothiazide; Lichen Planus; Methyldopa; Phenothiazines; Phenylbutazone; Quinacrine; Quinidine; Tetracycline; Thiazoles

1971

Other Studies

28 other study(ies) available for quinidine and hydrochlorothiazide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution prediction.
    Journal of medicinal chemistry, 2004, Jul-29, Volume: 47, Issue:16

    Topics: Chromatography, Affinity; Hydrogen-Ion Concentration; Ions; Models, Molecular; Molecular Conformation; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin, Bovine; Ultracentrifugation

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[Treatment of rhythm and conduction disorders].
    Kardiologiia, 1975, Volume: 15, Issue:1

    Topics: Adrenergic beta-Antagonists; Ajmaline; Arrhythmias, Cardiac; Atropine; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Inosine; Isoproterenol; Quinidine

1975
Anti-drug-related antibodies in nonthrombocytopenic cardiac patients.
    American journal of clinical pathology, 1976, Volume: 65, Issue:4

    Topics: Adult; Aged; Antibodies; Blood Platelets; Chromium Radioisotopes; Digoxin; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Platelet Factor 3; Purpura, Thrombocytopenic; Quinidine

1976
When a drug is the culprit.
    Geriatrics, 1973, Volume: 28, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effects and Adverse Reactions; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction; Nitrofurantoin; Nitroglycerin; Procainamide; Quinidine; Reserpine

1973
Hydrochlorothiazide-dependent thrombocytopenia due to IgM antibody.
    JAMA, 1971, Jan-18, Volume: 215, Issue:3

    Topics: Aged; Blood Cell Count; Blood Platelets; Complement Fixation Tests; Humans; Hydrochlorothiazide; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulin M; Macroglobulins; Male; Purpura, Thrombocytopenic; Quinidine; Quinine

1971
Refractory paroxysmal ventricular tachycardia.
    Annals of internal medicine, 1967, Volume: 67, Issue:6

    Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Electrocardiography; Heart Ventricles; Humans; Hydrochlorothiazide; Male; Middle Aged; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal

1967
Bigeminal rhythm on multiple cardiac drug therapy.
    Hospital practice (Office ed.), 1984, Volume: 19, Issue:2

    Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Digoxin; Drug Therapy, Combination; Electrocardiography; Furosemide; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Nitroglycerin; Potassium Chloride; Quinidine

1984
Intrahepatic distribution of hydrochlorothiazide and quinidine in rats: implications in pharmacokinetics.
    Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Infusions, Intravenous; Liver; Male; Quinidine; Rats; Rats, Sprague-Dawley; Tissue Distribution

1993
THE CARDIAC ATHLETE. RECENT STUDIES IN SPORTS MEDICINE.
    Texas state journal of medicine, 1964, Volume: 60

    Topics: Athletes; Atrial Fibrillation; Classification; Exercise Test; Heart; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Pharmaceutical Preparations; Quinidine; Reserpine; Sports Medicine; Tachycardia

1964
SMALL-BOWEL ULCERATION APPARENTLY ASSOCIATED WITH THIAZIDE AND POTASSIUM THERAPY.
    JAMA, 1964, Nov-16, Volume: 190

    Topics: Chlorides; Digitalis; Gastrointestinal Hemorrhage; Geriatrics; Gluconates; Humans; Hydrochlorothiazide; Ileum; Intestinal Diseases; Intestinal Obstruction; Intestinal Perforation; Intestine, Small; Iron; Jejunum; Pathology; Potassium; Potassium Chloride; Quinidine; Reserpine; Tablets; Tablets, Enteric-Coated; Thiazides; Thyroid Hormones; Toxicology; Ulcer

1964
pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs 1. Simultaneous determination of quinidine and permeability markers in rat in situ perfusion samples.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Feb-25, Volume: 816, Issue:1-2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Furosemide; Hydrochlorothiazide; Hydrogen-Ion Concentration; Intestinal Absorption; Permeability; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity

2005
pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Chromatography, High Pressure Liquid; Furosemide; Hydrochlorothiazide; Hydrogen-Ion Concentration; Ileum; Intestinal Absorption; Jejunum; Membranes, Artificial; Perfusion; Permeability; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Verapamil

2005