Page last updated: 2024-08-17

quinidine and flecainide

quinidine has been researched along with flecainide in 143 studies

Research

Studies (143)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (18.88)	18.7374
1990's	49 (34.27)	18.2507
2000's	40 (27.97)	29.6817
2010's	23 (16.08)	24.3611
2020's	4 (2.80)	2.80

Authors

Authors	Studies
Argentieri, TM; Gomez, RP; Lind, JM; Morgan, TK; Nickisch, K; Phillips, GB; Sullivan, ME; Wohl, RA	1
Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Arieff, Z; Bardien-Kruger, S; Brink, P; Chandy, KG; Corfield, V; Wulff, H	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Keserü, GM	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Abraham, S; Barrett, TD; Beatch, GN; Clohs, L; Dong, Y; Fedida, D; Jung, GL; Liu, Y; Lynn, L; Plouvier, B; Sheng, T; Walker, MJ; Wall, RA; Wang, WQ; Zhu, JJ; Zolotoy, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Dalvie, D; Loi, CM; Smith, DA	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Hsieh, MZ; Penz, W; Pugsley, M; Walker, MJ	1
Kanno, M; Nakaya, H; Oyama, Y; Shishido, Y	1
Lastra, AA; Nesterenko, VV; Rosenshtraukh, LV; Starmer, CF	1
Baĭer, T; Brakhmann, I; Khilbel, T; Kiubler, V; Shmitt, K; Valdeker, B	1
Biollaz, J; Buclin, T; Munafo, A; Tuto, D	1
Chouty, F; Coumel, P; Denjoy, I; Leclercq, JF; Slama, R	1
Lau, CP; Leung, WH; Wong, CK	1
Birgersdotter, UM; Roden, DM; Turgeon, J; Wong, W	1
Candinas, R; Follath, F; Meyer, B	1
Biour, M; Cheymol, G; Chézalviel, F; Davy, JM; Ertzbischoff, O; Harlé, X; Poirier, JM; Weissenburger, J	1
Brinker, J; Griffith, LS; Guarnieri, T; Tomaselli, G	1
Akaike, N; Inomata, N; Ishihara, T	1
Guize, L; Hatem, S; Lavergne, T; Le Grand, B; Le Heuzey, JY	1
Duker, BG	1
Crijns, HJ; Gosselink, AM; Hillege, H; Lie, KI; Van Gelder, IC; Van Gilst, WH	1
Cheymol, G; Chézalviel, F; Davy, JM; Engel, F; Ertzbischoff, O; Lainée, P; Motté, G; Penin, E; Poirier, JM; Weissenburger, J	1
Anderson, JL	1
Biollaz, J; Munafo, A; Reymond-Michel, G	1
Nattel, S; Pelletier, LC; Talajic, M; Wang, ZG	1
Keefe, DL; Miura, D; Somberg, JC	1
Crijns, HJ; den Heijer, P; Lie, KI; van Gilst, WH; van Wijk, LM	1
Hoffmeister, HM; Krämer, B; Pflug, A; Seipel, L	1
Scamps, F; Undrovinas, A; Vassort, G	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Roy, D	1
Echt, DS; Roden, DM; Woosley, RL	1
Morganroth, J; Nestico, PF	2
Huang, SK; Marcus, FI	1
Light, RT; Onrot, J; Robertson, D; Robertson, RM; Tantengco, MV	1
Kates, RE	1
Hepp, A; Hoffmeister, HM; Seipel, L	1
Bach, P; Doliwa, R; Steinbeck, G	1
Borgeat, A; Goy, JJ; Grbic, M; Kaufmann, U; Maendly, R; Sigwart, U	1
Podrid, PJ	1
Collignon, P; Legrand, V	1
Atarashi, H; Hayakawa, H	1
Hillis, WS; Whiting, B	1
Somberg, JC	1
Bricaud, H; Castagne, D; Clémenty, J; Dallocchio, M	1
Granrud, G; Hodges, M; Salerno, DM; Sharkey, P	1
Granrud, G; Hodges, M; Salerno, DM	1
Block, PJ; Winkle, RA	1
Banitt, EH; Kvam, DC; Schmid, JR	1
Grey, E; Silverman, DI	1
Chi, L; Fagbemi, SO; Lucchesi, BR	1
Fermini, B; Nattel, S; Wang, Z	1
Haberl, R; Knez, A; Steinbeck, G	1
Castle, NA; Slawsky, MT	1
Barchi, RL; Davison, K; Dugrenier, N; Estep, K; Ezrin, AM; Josef, K; Kallen, RG; Krafte, DS; Silver, PJ	1
Cowan, JC	1
Lüderitz, B; Manz, M	1
Brechenmacher, C; Chauvin, M; Koenig, A; Theolade, R	1
Blatt, CM; Graboys, TB; Lampert, S	1
Chow, MS; Fisher, JR; Kluger, J; Tisdale, JE	1
Barrett, TD; Hayes, ES; Walker, MJ	1
Camm, AJ; Sopher, SM	1
Coumel, P; Dorian, P; Hohnloser, SH; Naccarelli, GV	1
Iida, M; Kodama, I; Toyama, J	1
Catterall, WA; McPhee, JC; Ragsdale, DS; Scheuer, T	1
DiMarco, JP; Jung, F	1
Snyders, DJ; Yeola, SW	1
Beurrier, D; Brembilla-Perrot, B; Danchin, N; Houplon, P; Jacquemin, L; Louis, P; Terrier de la Chaise, A	1
Fernández del Pozo, B; Fernández, C; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá, F	1
Bellandi, F; Cantini, F; Dabizzi, RP; Mugnaioni, G; Palchetti, R	1
Adamantidis, M; Cardinal, R; Delfaut, P; Dupuis, B; Kacet, S; Klug, D; Lacroix, D	1
Epstein, LM; Huang, DT; Josephson, ME; Monahan, KM; Papageorgiou, P; Zimetbaum, P	1
D'Andrea, A; Ducceschi, V; Iacono, A; Liccardo, B; Santangelo, L; Sarubbi, B	1
Allessie, MA; Dorland, R; Wijffels, MC	1
Hancox, JC; Mitcheson, JS	1
Erzouki, HK; Goldberg, SR; Schindler, CW	1
Citra, M; Freedman, TB; Long, F; Nafie, LA	1
Feng, JL; Nattel, S; Wang, Z; Yue, L	1
Dell'Orfano, JT; Luck, JC; Naccarelli, GV; Patel, HM; Wolbrette, DL	1
Allessie, MA; Dorland, R; Mast, F; Wijffels, MC	1
Boyett, MR; Honjo, H; Kodama, I; Lei, M	1
Alings, M; Dekker, L; Sadée, A; Wilde, A	1
Curtis, MJ; Farkas, A	1
Hancox, JC; Paul, AA; Witchel, HJ	1
Aida, H; Hiraga, A; Kuwahara, M; Ohmura, H; Tsubone, H	1
Bhatta, L; Hynes, J; Khan, M; Luck, J; Naccarelli, GV; Samii, S; Wolbrette, DL	1
Kao, W; Kowey, PR; Winkel, E; Yan, GX	1
Caballero, R; Delpón, E; Nattel, S; Pourrier, M; Schram, G; Tamargo, J	1
Bauskin, A; Breit, S; Bursill, J; Campbell, T; Singarayar, S; Vandenberg, J; Wu, W; Wyse, K	1
Antzelevitch, C; Bianchi, F; Borggrefe, M; Brugada, R; Calò, L; Gaita, F; Giustetto, C; Haissaguerre, M; Schimpf, R; Wolpert, C	1
Belhassen, B; Glick, A; Viskin, S	1
Dorian, P; Humphries, KH; Kerr, CR; Steinbuch, M	1
Scharf, C	1
Colledge, WH; Goddard, CA; Grace, AA; Huang, CL; Stokoe, KS; Thomas, G	1
Balasubramaniam, R; Colledge, WH; Goddard, CA; Grace, AA; Huang, CL; Stokoe, KS	1
Ai, T; Cheng, J; Li, Z; Merkle, EM; Razavi, M; Shuraih, M; Sohma, Y; Taylor, E; Towbin, JA; Vatta, M; Xi, Y	1
Chen, YW; Cheng, KI; Chu, CC; Chu, KS; Huang, KL; Tzeng, JI; Wang, JJ	1
Borggrefe, M; Breithardt, G; Eckardt, L; Milberg, P; Osada, N; Schimpf, R; Tegelkamp, R; Wolpert, C	1
Kaufman, ES	1
Birettoni, F; della Rocca, G; Di Salvo, A; Porciello, F; Rishniw, M; Sgorbini, M	1
Goddard, CA; Grace, AA; Huang, CL; Jones, VJ; Li, LM; Sabir, IN	1
Dautova, Y; Grace, AA; Huang, CL; Sabir, I; Zhang, Y	1
Giacomini, KM; Kim, RB; Liu, K; McBride, BF; Roden, DM; Urban, TJ; Yang, T	1
Grace, AA; Hakim, P; Huang, CL; Thresher, R	1
Dautova, Y; Grace, AA; Huang, CL; Zhang, Y	1
Grace, AA; Huang, CL; Martin, CA	2
Chen, YC; Chen, YW; Chu, CC; Leung, YM; Wang, JJ	1
Cros, C; Lainee, P; Moors, J; Skinner, M; Valentin, JP	1
Grace, AA; Guzadhur, L; Huang, CL; Matthews, GD; Sabir, IN	1
Osadchii, OE	5
Bergenholm, L; Chappell, MJ; Collins, T; Evans, ND; Mettetal, J; Parkinson, J	1
Kleinlogel, S; Streit, J	1
Ishikawa, Y; Ohmura, H; Takahashi, Y	1
Hinoi, E; Miyawaki, I; Tsubouchi, T; Watanabe, K; Yamada, T	1
Kawai, T; Kuninishi, Y; Muraki, Y; Nogawa, H	1
Bove, T; Cilenti, F; Copetti, R; Cristiani, L; Guglielmo, N; Orso, D; Santangelo, S	1

Reviews

23 review(s) available for quinidine and flecainide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Comparisons of efficacy and tolerance of moricizine with other antiarrhythmic agents in the treatment of chronic ventricular arrhythmias. The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Double-Blind Method; Encainide; Female; Flecainide; Humans; Male; Moricizine; Phenothiazines; Propranolol; Quinidine; Randomized Controlled Trials as Topic	1990
The treatment of ventricular rhythm disturbances. American heart journal, 1986, Volume: 111, Issue:6 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Electric Countershock; Electric Stimulation; Electrocardiography; Exercise Test; Flecainide; Heart Ventricles; Humans; Lidocaine; Phenytoin; Piperidines; Procainamide; Quinidine; Risk; Tachycardia; Tocainide; United States; Ventricular Fibrillation; Verapamil	1986
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drugs. Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2 Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1986
Effects of congestive heart failure on the pharmacokinetics and pharmacodynamics of antiarrhythmic agents. The American journal of cardiology, 1986, Jan-31, Volume: 57, Issue:3 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Digitalis; Disopyramide; Drug Interactions; Encainide; Flecainide; Half-Life; Heart Failure; Hemodynamics; Humans; Kidney; Kinetics; Lidocaine; Liver; Piperidines; Plants, Medicinal; Plants, Toxic; Potassium; Procainamide; Quinidine; Regional Blood Flow; Tocainide	1986
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment. Cardiology clinics, 1986, Volume: 4, Issue:2 Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil	1986
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
Antiarrhythmic agents for chronic ventricular arrhythmias. Comprehensive therapy, 1987, Volume: 13, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide	1987
Hemodynamic effects of antiarrhythmic drugs. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide	1983
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy. European heart journal, 1993, Volume: 14 Suppl E Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Flecainide; Humans; Imidazoles; Pre-Excitation Syndromes; Propafenone; Quinidine; Sotalol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Verapamil	1993
[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock]. Presse medicale (Paris, France : 1983), 1993, Nov-20, Volume: 22, Issue:36 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Disopyramide; Electric Countershock; Flecainide; Humans; Propafenone; Quinidine; Recurrence; Sotalol	1993
Atrial fibrillation: maintenance of sinus rhythm versus rate control. The American journal of cardiology, 1996, Jan-25, Volume: 77, Issue:3 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Calcium Channel Blockers; Catheter Ablation; Digoxin; Electric Countershock; Flecainide; Heart Failure; Heart Rate; Heart Ventricles; Humans; Quinidine; Sinoatrial Node; Thromboembolism; Time Factors	1996
Antiarrhythmic drug therapy in the treatment of atrial fibrillation. Cardiology clinics, 1996, Volume: 14, Issue:4 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Electrophysiology; Flecainide; Humans; Ion Channels; Quinidine; Sotalol; Sulfonamides	1996
Atrial fibrillation: what are the effects of drug therapy on the effectiveness and complications of electrical cardioversion? The Canadian journal of cardiology, 1998, Volume: 14, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Digoxin; Electric Countershock; Flecainide; Humans; Procainamide; Quinidine; Verapamil	1998
Cost-effective management of acute atrial fibrillation: role of rate control, spontaneous conversion, medical and direct current cardioversion, transesophageal echocardiography, and antiembolic therapy. The American journal of cardiology, 2000, May-25, Volume: 85, Issue:10A Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cost-Benefit Analysis; Echocardiography, Transesophageal; Electric Countershock; Flecainide; Humans; Procainamide; Propafenone; Quinidine; Sotalol; Verapamil	2000
Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Australia; Canada; Controlled Clinical Trials as Topic; Europe; Flecainide; Heart Conduction System; Heart Failure; Humans; Multicenter Studies as Topic; Myocardial Infarction; Phenethylamines; Propafenone; Quinidine; Sotalol; Sulfonamides; Survival Analysis; Therapeutic Equivalency; Treatment Outcome; United States	2003
Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Flecainide; Heart Rate; Humans; Phenethylamines; Practice Guidelines as Topic; Propafenone; Quinidine; Stroke; Sulfonamides; Ventricular Dysfunction, Left	2003
Efficacy of quinidine in high-risk patients with Brugada syndrome. Circulation, 2004, Sep-28, Volume: 110, Issue:13 Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cohort Studies; Death, Sudden, Cardiac; Defibrillators, Implantable; Drug Evaluation; Electric Countershock; Electrocardiography; Female; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Prospective Studies; Quinidine; Retrospective Studies; Risk; Shal Potassium Channels; Syndrome; Ventricular Fibrillation	2004
[Atrial flutter and fibrillation]. Praxis, 2005, Nov-09, Volume: 94, Issue:45 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Calcium Channel Blockers; Catheter Ablation; Clinical Trials as Topic; Disopyramide; Electric Countershock; Electrocardiography; Emergencies; Flecainide; Heart Rate; Humans; Middle Aged; Pacemaker, Artificial; Propafenone; Quinidine; Recurrence; Sotalol; Sulfonamides; Treatment Outcome; Vasodilator Agents	2005
Quinidine in short QT syndrome: an old drug for a new disease. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Electrocardiography; Electrophysiologic Techniques, Cardiac; Flecainide; Genetic Predisposition to Disease; Humans; Quinidine; Rabbits; Sotalol; Treatment Outcome	2007
Bayesian Network Meta-analysis of Randomized Controlled Trials on the Efficacy of Antiarrhythmics in the Pharmacological Cardioversion of Paroxysmal Atrial Fibrillation. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2023, Volume: 23, Issue:4 Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Flecainide; Humans; Network Meta-Analysis; Quinidine; Randomized Controlled Trials as Topic; Ranolazine; Systematic Reviews as Topic; Verapamil	2023

Trials

16 trial(s) available for quinidine and flecainide

Article	Year
The effect of a low dose of quinidine on the disposition of flecainide in healthy volunteers. European journal of clinical pharmacology, 1992, Volume: 43, Issue:4 Topics: Adult; Drug Interactions; Electrocardiography; Flecainide; Humans; Infusions, Intravenous; Male; Quinidine; Time Factors	1992
A randomized double-blind crossover study comparing the efficacy and tolerability of flecainide and quinidine in the control of patients with symptomatic paroxysmal atrial fibrillation. American heart journal, 1992, Volume: 124, Issue:3 Topics: Adult; Aged; Atrial Fibrillation; Chi-Square Distribution; Double-Blind Method; Electrocardiography, Ambulatory; Female; Flecainide; Follow-Up Studies; Gastrointestinal Diseases; Humans; Life Tables; Male; Middle Aged; Quinidine; Recurrence; Treatment Outcome; Vision Disorders	1992
Comparisons of efficacy and tolerance of moricizine with other antiarrhythmic agents in the treatment of chronic ventricular arrhythmias. The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Double-Blind Method; Encainide; Female; Flecainide; Humans; Male; Moricizine; Phenothiazines; Propranolol; Quinidine; Randomized Controlled Trials as Topic	1990
Flecainide versus quinidine in the prevention of paroxysms of atrial fibrillation. Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:1 Topics: Adult; Aged; Atrial Fibrillation; Female; Flecainide; Humans; Male; Middle Aged; Quinidine; Random Allocation	1989
[Therapy of paroxysmal atrial fibrillation. Cardiac glycosides alone or combined with anti-arrhythmia agents?]. Deutsche medizinische Wochenschrift (1946), 1988, Dec-02, Volume: 113, Issue:48 Topics: Administration, Oral; Aged; Atrial Fibrillation; Clinical Trials as Topic; Digoxin; Drug Therapy, Combination; Female; Flecainide; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Random Allocation; Time Factors	1988
Flecainide versus quinidine for conversion of atrial fibrillation to sinus rhythm. The American journal of cardiology, 1986, Sep-01, Volume: 58, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Female; Flecainide; Heart; Heart Rate; Humans; Male; Middle Aged; Piperidines; Quinidine; Radiography	1986
[Comparative study of a slow-release quinidine preparation and flecainide administered in 2 daily doses for the treatment of extrasystole]. Annales de cardiologie et d'angeiologie, 1984, Volume: 33, Issue:6 Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Delayed-Action Preparations; Drug Administration Schedule; Electrocardiography; Female; Flecainide; Humans; Male; Middle Aged; Monitoring, Physiologic; Piperidines; Quinidine	1984
Flecainide versus quinidine for treatment of chronic ventricular arrhythmias. A multicenter clinical trial. Circulation, 1983, Volume: 67, Issue:5 Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Flecainide; Heart Ventricles; Humans; Male; Middle Aged; Piperidines; Quinidine; Random Allocation; Tachycardia	1983
Comparison of flecainide with quinidine for suppression of chronic stable ventricular ectopic depolarizations. A double-blind randomized study in ambulatory outpatients. Annals of internal medicine, 1983, Volume: 98, Issue:4 Topics: Adult; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Flecainide; Heart Ventricles; Humans; Male; Middle Aged; Piperidines; Quinidine; Random Allocation	1983
Flecainide versus quinidine: results of a multicenter trial. The American journal of cardiology, 1984, Feb-27, Volume: 53, Issue:5 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Flecainide; Humans; Piperidines; Quinidine; Random Allocation	1984
[The use of digitalis glycosides in atrial fibrillation]. Zeitschrift fur Kardiologie, 1994, Volume: 83 Suppl 5 Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Digoxin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Tachycardia, Paroxysmal	1994
Prospective comparison of flecainide versus quinidine for the treatment of paroxysmal atrial fibrillation/flutter. The Flecainide Multicenter Atrial Fibrillation Study Group. The American journal of cardiology, 1996, Jan-25, Volume: 77, Issue:3 Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Female; Flecainide; Follow-Up Studies; Humans; Life Tables; Male; Middle Aged; Prospective Studies; Quinidine	1996
Influence of quinidine and flecainide on autonomic nervous activity in thoroughbred horses. The Veterinary record, 2003, Jan-25, Volume: 152, Issue:4 Topics: Animals; Autonomic Nervous System; Diarrhea; Female; Flecainide; Heart Rate; Horses; Male; Quinidine	2003
Short QT syndrome: pharmacological treatment. Journal of the American College of Cardiology, 2004, Apr-21, Volume: 43, Issue:8 Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Female; Flecainide; Humans; Male; Quinidine; Sotalol; Syndrome; Treatment Outcome	2004
Treatment of chronic atrial fibrillation in the horse with flecainide: personal observation. Veterinary research communications, 2007, Volume: 31 Suppl 1 Topics: Animals; Anti-Arrhythmia Agents; Area Under Curve; Atrial Fibrillation; Chronic Disease; Flecainide; Half-Life; Horse Diseases; Horses; Quinidine	2007
Predicting QRS and PR interval prolongations in humans using nonclinical data. British journal of pharmacology, 2017, Volume: 174, Issue:19 Topics: Animals; Anti-Arrhythmia Agents; Azabicyclo Compounds; Carbamates; Dogs; Drug Evaluation, Preclinical; Electrocardiography; Flecainide; Guinea Pigs; Heart; Heart Rate; Humans; Long QT Syndrome; Male; Models, Biological; Quinidine; Verapamil	2017

Other Studies

105 other study(ies) available for quinidine and flecainide

Article	Year
Synthesis and cardiac electrophysiological activity of aryl-substituted derivatives of the class III antiarrhythmic agent sematilide. Potential class I/III agents. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chemical Phenomena; Chemistry; Dogs; Drug Design; Electrophysiology; Guinea Pigs; In Vitro Techniques; Ouabain; Procainamide; Purkinje Fibers; Structure-Activity Relationship	1990
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents. Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship	1993
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI). European journal of human genetics : EJHG, 2002, Volume: 10, Issue:1 Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; COS Cells; DNA; Heart Block; Heart Diseases; Humans; Mice; Molecular Sequence Data; Potassium Channels; Potassium Channels, Voltage-Gated; Shaker Superfamily of Potassium Channels; Trinucleotide Repeats	2002
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Synthesis and biological studies of novel 2-aminoalkylethers as potential antiarrhythmic agents for the conversion of atrial fibrillation. Journal of medicinal chemistry, 2007, Jun-14, Volume: 50, Issue:12 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Biological Availability; Cell Line; Crystallography, X-Ray; Cyclohexanes; Dogs; Electric Stimulation; Ethers; Female; Humans; Male; Mice; Molecular Structure; Myocardial Ischemia; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium Channels; Stereoisomerism; Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
A new ECG measure (RSh) for detecting possible sodium channel blockade in vivo in rats. Journal of pharmacological and toxicological methods, 1992, Volume: 27, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Flecainide; Heart Rate; Lidocaine; Male; Quinidine; Rats; Rats, Inbred Strains; Sodium; Sodium Channels	1992
Voltage-dependent modification of Vmax recovery from use-dependent block by pirmenol in guinea pig papillary muscles: comparison with other class I drugs. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Flecainide; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Mexiletine; Microelectrodes; Neuromuscular Depolarizing Agents; Papillary Muscles; Piperidines; Propylamines; Pyridines; Quinidine; Sodium Channels	1992
A proarrhythmic response to sodium channel blockade: modulation of the vulnerable period in guinea pig ventricular myocardium. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:5 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Flecainide; Guinea Pigs; Heart; In Vitro Techniques; Moricizine; Quinidine; Sodium Channels	1992
[Anti-arrhythmia agents in heart failure]. Kardiologiia, 1992, Volume: 32, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Flecainide; Humans; Mexiletine; Middle Aged; Propafenone; Quinidine	1992
Flecainide in quinidine-resistant atrial fibrillation. The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5 Topics: Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged; Quinidine; Time Factors	1992
Stereoselective genetically-determined interaction between chronic flecainide and quinidine in patients with arrhythmias. British journal of clinical pharmacology, 1992, Volume: 33, Issue:3 Topics: Arrhythmias, Cardiac; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Drug Interactions; Flecainide; Humans; Mixed Function Oxygenases; Polymorphism, Genetic; Quinidine	1992
[Drug therapy in supraventricular arrhythmia]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992, Apr-28, Volume: 81, Issue:18 Topics: Amiodarone; Anti-Arrhythmia Agents; Digoxin; Flecainide; Humans; Quinidine; Tachycardia, Supraventricular	1992
Comparison of the cardiac electrophysiological effects of flecainide and hydroquinidine in anesthetized dog: concentration-response relationship. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:1 Topics: Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Female; Flecainide; Heart; Heart Conduction System; Male; Quinidine; Refractory Period, Electrophysiological; Sinoatrial Node	1990
The interaction of antiarrhythmic drugs and the energy for cardioversion of chronic atrial fibrillation. Pacing and clinical electrophysiology : PACE, 1991, Volume: 14, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cerebrovascular Disorders; Chronic Disease; Electric Countershock; Electrocardiography; Energy Transfer; Female; Flecainide; Humans; Male; Middle Aged; Quinidine; Stroke Volume; Time Factors	1991
Mechanisms of the anticholinergic effect of SUN 1165 in comparison with flecainide, disopyramide and quinidine in single atrial myocytes isolated from guinea-pig. British journal of pharmacology, 1991, Volume: 104, Issue:4 Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Flecainide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardium; Parasympatholytics; Potassium Channels; Quinidine; Receptors, Cholinergic	1991
Cellular electropharmacology of human atrium: effects of antiarrhythmic drugs. Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:8 Suppl Topics: Action Potentials; Anti-Arrhythmia Agents; Atrial Function; Electrophysiology; Flecainide; Heart Atria; Humans; In Vitro Techniques; Quinidine	1991
Frequency dependent effects of tocainide, quinidine, and flecainide on conduction as reflected in the rise time of the monophasic action potential in the isolated guinea pig heart. Cardiovascular research, 1991, Volume: 25, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Flecainide; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Kinetics; Lidocaine; Quinidine; Tocainide	1991
Serial antiarrhythmic drug treatment to maintain sinus rhythm after electrical cardioversion for chronic atrial fibrillation or atrial flutter. The American journal of cardiology, 1991, Aug-01, Volume: 68, Issue:4 Topics: Actuarial Analysis; Aged; Amiodarone; Analysis of Variance; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Drug Administration Schedule; Electric Countershock; Female; Flecainide; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Quinidine; Recurrence; Sotalol	1991
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, Ambulatory; Electrolytes; Electrophysiology; Female; Flecainide; Heart Block; Hypocalcemia; Lidocaine; Male; Propranolol; Quinidine; Sotalol	1991
Altered flecainide disposition in healthy volunteers taking quinine. European journal of clinical pharmacology, 1990, Volume: 38, Issue:3 Topics: Adult; Biotransformation; Cimetidine; Drug Interactions; Electrocardiography; Flecainide; Half-Life; Heart Rate; Humans; Male; Quinidine; Quinine; Reference Values	1990
Effects of flecainide and quinidine on human atrial action potentials. Role of rate-dependence and comparison with guinea pig, rabbit, and dog tissues. Circulation, 1990, Volume: 82, Issue:1 Topics: Action Potentials; Aged; Animals; Dogs; Female; Flecainide; Guinea Pigs; Heart; Heart Atria; Heart Rate; Humans; Male; Middle Aged; Quinidine; Rabbits	1990
Circulatory and myocardial effects of different sodium antagonistic drugs in comparison to the calcium antagonist verapamil. Arzneimittel-Forschung, 1989, Volume: 39, Issue:11 Topics: Animals; Cardiac Output; Disopyramide; Flecainide; Heart; Hemodynamics; In Vitro Techniques; Injections, Intravenous; Male; Quinidine; Rats; Rats, Inbred Strains; Sodium; Verapamil	1989
Inhibition of ICa in single frog cardiac cells by quinidine, flecainide, ethmozin, and ethacizin. The American journal of physiology, 1989, Volume: 256, Issue:3 Pt 1 Topics: Animals; Anti-Arrhythmia Agents; Calcium Channels; Flecainide; Heart; In Vitro Techniques; Membrane Potentials; Moricizine; Phenothiazines; Quinidine; Rana esculenta	1989
Orthostatic hypotension: clinical spectrum and approach to treatment. Comprehensive therapy, 1986, Volume: 12, Issue:6 Topics: Adult; Aged; Amiodarone; Disopyramide; Female; Flecainide; Humans; Hypotension, Orthostatic; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Quinidine; Sympathomimetics; Tocainide	1986
Metabolites of antiarrhythmic drugs: are they clinically important? Rational drug therapy, 1986, Volume: 20, Issue:5 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Procainamide; Quinidine	1986
Negative inotropic effect of class-I-antiarrhythmic drugs: comparison of flecainide with disopyramide and quinidine. European heart journal, 1987, Volume: 8, Issue:10 Topics: Animals; Cardiac Volume; Depression, Chemical; Disopyramide; Flecainide; Male; Myocardial Contraction; Pressure; Quinidine; Rats; Rats, Inbred Strains	1987
Aggravation of ventricular arrhythmia. A drug-induced complication. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
Haemodynamic effects of class I antiarrhythmic agents. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anti-Arrhythmia Agents; Disopyramide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1985
[Anti-arrhythmia agents (I): Quinidine, procainamide, disopyramide, encainide, propafenone and flecainide]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
Antiarrhythmic drugs. British medical journal (Clinical research ed.), 1983, Apr-23, Volume: 286, Issue:6374 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil	1983
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
Antiarrhythmic and electrophysiologic actions of flecainide in animal models. The American journal of cardiology, 1984, Feb-27, Volume: 53, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electrophysiology; Flecainide; Heart Conduction System; In Vitro Techniques; Lidocaine; Piperidines; Procainamide; Quinidine; Rabbits	1984
Efficacy of type 1C antiarrhythmic agents for treatment of resistant atrial fibrillation. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:12 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Encainide; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Procainamide; Propafenone; Quinidine; Recurrence; Retrospective Studies	1993
Antifibrillatory and profibrillatory actions of selected class I antiarrhythmic agents. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:5 Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Blood Gas Analysis; Electrophysiology; Flecainide; Glyburide; Guanidines; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Pinacidil; Potassium Channels; Quinidine; Rabbits; Refractory Period, Electrophysiological; Vasodilator Agents	1993
Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1 Topics: 4-Aminopyridine; Dose-Response Relationship, Drug; Flecainide; Heart Atria; Humans; In Vitro Techniques; Ion Channel Gating; Middle Aged; Potassium; Potassium Channels; Quinidine	1995
K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Cells, Cultured; Electrophysiology; Flecainide; Heart; Heart Ventricles; Kinetics; Potassium Channels; Propafenone; Quinidine; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity	1994
Pharmacological modulation of human cardiac Na+ channels. European journal of pharmacology, 1994, Feb-15, Volume: 266, Issue:3 Topics: Animals; Azetidines; Cardiotonic Agents; Electrophysiology; Female; Flecainide; Humans; Lidocaine; Mercaptopurine; Myocardium; Oocytes; Piperazines; Quinidine; RNA, Complementary; Sodium Channels; Tetrodotoxin; Transcription, Genetic; Xenopus laevis	1994
Antiarrhythmic drugs in the management of atrial fibrillation. British heart journal, 1993, Volume: 70, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Flecainide; Heart; Humans; Propafenone; Quinidine	1993
Is exercise testing safe in patients treated with flecainide for atrial arrhythmia? American heart journal, 1993, Volume: 126, Issue:1 Topics: Contraindications; Exercise Test; Flecainide; Humans; Quinidine; Tachycardia, Supraventricular	1993
Efficacy of class 1C antiarrhythmic agents in patients with inducible ventricular tachycardia refractory to therapy with class 1A antiarrhythmic drugs. Journal of clinical pharmacology, 1993, Volume: 33, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Benzeneacetamides; Electric Stimulation; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Piperidines; Quinidine; Retrospective Studies; Stroke Volume; Tachycardia, Ventricular	1993
Lack of selectivity for ventricular and ischaemic tissue limits the antiarrhythmic actions of lidocaine, quinidine and flecainide against ischaemia-induced arrhythmias. European journal of pharmacology, 1995, Oct-24, Volume: 285, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Flecainide; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Lidocaine; Male; Myocardial Ischemia; Quinidine; Rats; Rats, Sprague-Dawley	1995
Negative dromotropic effects of class I antiarrhythmic drugs in anisotropic ventricular muscle. Cardiovascular research, 1996, Volume: 31, Issue:4 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aprindine; Calcium Channel Blockers; Dose-Response Relationship, Drug; Flecainide; Heart Conduction System; In Vitro Techniques; Membrane Potentials; Quinidine; Rabbits; Sodium Channels; Thiazoles	1996
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-20, Volume: 93, Issue:17 Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Binding Sites; Dose-Response Relationship, Drug; Flecainide; Ion Channel Gating; Lidocaine; Mutagenesis, Site-Directed; Mutation; Phenytoin; Quinidine; Rats; Recombinant Proteins; Sodium Channels; Structure-Activity Relationship	1996
Electrophysiological and pharmacological correspondence between Kv4.2 current and rat cardiac transient outward current. Cardiovascular research, 1997, Volume: 33, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Biological Transport, Active; Cell Line; Flecainide; Heart; Humans; Patch-Clamp Techniques; Potassium Channels; Quinidine; Rats; Shal Potassium Channels	1997
[Can 1/1 atrial flutter be foreseen by class I anti-arrhythmics?]. Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:7 Topics: Aged; Anti-Arrhythmia Agents; Atrial Flutter; Disopyramide; Electrocardiography; Female; Flecainide; Heart Conduction System; Humans; Imidazoles; Male; Middle Aged; Predictive Value of Tests; Propafenone; Quinidine; Risk Factors	1997
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle. General pharmacology, 1997, Volume: 29, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Aorta; Desipramine; Disopyramide; Flecainide; Imipramine; In Vitro Techniques; Lidocaine; Male; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Quinidine; Rats; Rats, Sprague-Dawley	1997
[Pharmacological cardioversion of isolated atrial fibrillation: recovery of atrial mechanical function and correlation with duration of arrhythmia]. Giornale italiano di cardiologia, 1997, Volume: 27, Issue:10 Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Data Interpretation, Statistical; Echocardiography, Doppler, Pulsed; Female; Flecainide; Follow-Up Studies; Hemodynamics; Humans; Male; Middle Aged; Propafenone; Quinidine; Recurrence; Time Factors	1997
Differential effects of quinidine, flecainide, and cibenzoline on anisotropic conduction in the isolated porcine heart. Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:1 Topics: Action Potentials; Animals; Anisotropy; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiac Pacing, Artificial; Female; Flecainide; Heart; Heart Conduction System; Imidazoles; In Vitro Techniques; Pericardium; Potassium Channel Blockers; Quinidine; Swine	1998
Hybrid pharmacologic and ablative therapy: a novel and effective approach for the management of atrial fibrillation. Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged; Propafenone; Quinidine	1998
Pharmacologic cardioversion of chronic atrial fibrillation in the goat by class IA, IC, and III drugs: a comparison between hydroquinidine, cibenzoline, flecainide, and d-sotalol. Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Disease Models, Animal; Electrocardiography; Flecainide; Follow-Up Studies; Goats; Heart Conduction System; Imidazoles; Injections, Intravenous; Quinidine; Secondary Prevention; Sotalol; Treatment Outcome	1999
Characteristics of a transient outward current (sensitive to 4-aminopyridine) in Ca2+-tolerant myocytes isolated from the rabbit atrioventricular node. Pflugers Archiv : European journal of physiology, 1999, Volume: 438, Issue:1 Topics: 4-Aminopyridine; Action Potentials; Algorithms; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Electrophysiology; Flecainide; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Quinidine; Rabbits	1999
Comparison of cocaine and Na+ channel blockers on cardio-respiratory function in the rabbit. European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cocaine; Dopamine Uptake Inhibitors; Electrocardiography; Female; Flecainide; Heart; Heart Rate; Lidocaine; Male; Procainamide; Quinidine; Rabbits; Respiration; Sodium Channel Blockers	1999
Hydrogen-stretching vibrational circular dichroism spectroscopy: absolute configuration and solution conformation of selected pharmaceutical molecules. Enantiomer, 1999, Volume: 4, Issue:2 Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Circular Dichroism; Flecainide; Hydrogen; Ibuprofen; Models, Molecular; Molecular Conformation; Molecular Structure; Naphthalenes; Naproxen; Propranolol; Pyrrolidinones; Quinidine; Vibration	1999
Effects of ambasilide, quinidine, flecainide and verapamil on ultra-rapid delayed rectifier potassium currents in canine atrial myocytes. Cardiovascular research, 2000, Volume: 46, Issue:1 Topics: Aminobenzoates; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channels, L-Type; Dogs; Dose-Response Relationship, Drug; Flecainide; Heart Atria; Myocardium; Patch-Clamp Techniques; Potassium Channels; Quinidine; Time Factors; Verapamil	2000
Widening of the excitable gap during pharmacological cardioversion of atrial fibrillation in the goat: effects of cibenzoline, hydroquinidine, flecainide, and d-sotalol. Circulation, 2000, Jul-11, Volume: 102, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Flecainide; Goats; Heart Conduction System; Imidazoles; Quinidine; Sotalol	2000
Characterisation of the transient outward K+ current in rabbit sinoatrial node cells. Cardiovascular research, 2000, Volume: 46, Issue:3 Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Cell Size; Flecainide; Linear Models; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Quinidine; Rabbits; Sinoatrial Node	2000
Quinidine induced electrocardiographic normalization in two patients with Brugada syndrome. Pacing and clinical electrophysiology : PACE, 2001, Volume: 24, Issue:9 Pt 1 Topics: Adult; Electrocardiography; Flecainide; Humans; Male; Middle Aged; Quinidine; Syndrome; Treatment Outcome; Ventricular Fibrillation	2001
Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Flecainide; Heart; Heart Rate; In Vitro Techniques; Lidocaine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Chloride; Quinidine; Rats; Rats, Wistar; Ventricular Fibrillation	2002
Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine. British journal of pharmacology, 2002, Volume: 136, Issue:5 Topics: Cation Transport Proteins; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flecainide; Humans; Lidocaine; Neural Inhibition; Potassium Channels; Potassium Channels, Voltage-Gated; Propafenone; Quinidine; Trans-Activators; Transcriptional Regulator ERG	2002
Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines. British journal of pharmacology, 2003, Volume: 138, Issue:8 Topics: Animals; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Flecainide; Membrane Potentials; Mutation; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Rats; Shal Potassium Channels; Valine	2003
Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine. Journal of cardiovascular electrophysiology, 2003, Volume: 14, Issue:6 Topics: Acidosis; Animals; Anti-Arrhythmia Agents; Biological Transport, Active; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Female; Flecainide; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Models, Cardiovascular; Ovary; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sensitivity and Specificity; Shal Potassium Channels; Statistics as Topic; Time Factors	2003
Atrial fibrillation: rate control often better than rhythm control. Prescrire international, 2004, Volume: 13, Issue:70 Topics: Adult; Aged; Amiodarone; Anticoagulants; Arrhythmia, Sinus; Atrial Fibrillation; Canada; Disopyramide; Electric Countershock; Flecainide; Heart Rate; Humans; Netherlands; Platelet Aggregation Inhibitors; Propafenone; Quinidine; Sotalol; United States	2004
Limitations to antiarrhythmic drug use in patients with atrial fibrillation. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Sep-28, Volume: 171, Issue:7 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Canada; Contraindications; Female; Flecainide; Humans; Male; Middle Aged; Propafenone; Quinidine; Registries; Sotalol	2004
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3. The Journal of physiology, 2007, Jan-01, Volume: 578, Issue:Pt 1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Electric Stimulation; Electrocardiography; Electrophysiology; Female; Flecainide; Heart; Heart Conduction System; In Vitro Techniques; Long QT Syndrome; Male; Mice; Mice, Transgenic; NAV1.5 Voltage-Gated Sodium Channel; Quinidine; Sodium Channels	2007
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome. The Journal of physiology, 2007, May-15, Volume: 581, Issue:Pt 1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Disease Models, Animal; Electric Stimulation; Electrophysiology; Female; Flecainide; Gene Expression Regulation; Heart; Male; Mice; Mice, Inbred Strains; NAV1.5 Voltage-Gated Sodium Channel; Quinidine; Sodium Channels	2007
A common SCN5A variant alters the responsiveness of human sodium channels to class I antiarrhythmic agents. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:4 Topics: Anti-Arrhythmia Agents; Cells, Cultured; Flecainide; Genetic Variation; Humans; Ion Channel Gating; Mexiletine; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Quinidine; Sodium Channels	2007
The cutaneous analgesic effect of class I antiarrhythmic drugs. Anesthesia and analgesia, 2007, Volume: 104, Issue:4 Topics: Analgesics; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Bupivacaine; Dose-Response Relationship, Drug; Flecainide; Injections, Subcutaneous; Lidocaine; Male; Mexiletine; Pain Measurement; Pain Threshold; Quinidine; Rats; Rats, Sprague-Dawley; Reflex; Skin; Sodium Channel Blockers; Time Factors	2007
Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:6 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Flecainide; Heart Conduction System; In Vitro Techniques; Pinacidil; Quinidine; Rabbits; Random Allocation; Refractory Period, Electrophysiological; Sotalol; Vasodilator Agents	2007
Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome. Pflugers Archiv : European journal of physiology, 2008, Volume: 455, Issue:4 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Brugada Syndrome; Cardiac Pacing, Artificial; Disease Models, Animal; Electrocardiography; Endocardium; Flecainide; Heart Rate; Long QT Syndrome; Mice; Mice, Transgenic; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Perfusion; Pericardium; Quinidine; Sodium Channels; Time Factors	2008
Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome. Pflugers Archiv : European journal of physiology, 2009, Volume: 458, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Models, Animal; Flecainide; Heart Rate; Humans; Long QT Syndrome; Mice; Mice, Transgenic; NAV1.5 Voltage-Gated Sodium Channel; Quinidine; Sodium Channels; Treatment Outcome	2009
The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel. Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:1 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cation Transport Proteins; Electrophysiology; Ether-A-Go-Go Potassium Channels; Flecainide; Gene Expression; Heart; Humans; Immunohistochemistry; In Situ Hybridization; Inhibitory Concentration 50; Myocytes, Cardiac; Organic Cation Transport Proteins; Patch-Clamp Techniques; Potassium Channels; Quinidine; Sulfonamides; Symporters	2009
Effects of flecainide and quinidine on action potential and ventricular arrhythmogenic properties in Scn3b knockout mice. Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:8 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electric Stimulation; Endocardium; Flecainide; Mice; Mice, Knockout; Pericardium; Quinidine; Refractory Period, Electrophysiological	2010
Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts. Experimental physiology, 2010, Volume: 95, Issue:10 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Function; Brugada Syndrome; Cardiac Pacing, Artificial; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Flecainide; Heart Atria; Heart Ventricles; Mice; Mice, 129 Strain; Mice, Transgenic; NAV1.5 Voltage-Gated Sodium Channel; Perfusion; Quinidine; Sodium Channels; Time Factors; Ventricular Function	2010
Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model. American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:2 Topics: Action Potentials; Algorithms; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Electrocardiography; Electrophysiological Phenomena; Flecainide; Heterozygote; In Vitro Techniques; Mice; Mice, Knockout; NAV1.5 Voltage-Gated Sodium Channel; Pericardium; Quinidine; Refractory Period, Electrophysiological; Sodium Channels; Ventricular Function, Left; Ventricular Function, Right	2011
Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a (+/-) mouse model. Pflugers Archiv : European journal of physiology, 2011, Volume: 462, Issue:4 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Electric Stimulation; Flecainide; Heart; Heart Ventricles; Ion Channel Gating; Mice; NAV1.5 Voltage-Gated Sodium Channel; Quinidine; Refractory Period, Electrophysiological; Sodium Channels	2011
Spinal blockades of class I antiarrythmic drugs with bupivacaine by isobolographic analysis in rats. Neuroscience letters, 2012, Oct-18, Volume: 528, Issue:1 Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Bupivacaine; Dose-Response Relationship, Drug; Flecainide; Injections, Spinal; Male; Mexiletine; Quinidine; Rats; Rats, Sprague-Dawley	2012
Detecting drug-induced prolongation of the QRS complex: new insights for cardiac safety assessment. Toxicology and applied pharmacology, 2012, Dec-01, Volume: 265, Issue:2 Topics: Animals; CHO Cells; Cricetinae; Dogs; Electrocardiography; Flecainide; Heart Rate; Male; Mexiletine; Patch-Clamp Techniques; Quinidine; Telemetry; Voltage-Gated Sodium Channel Blockers	2012
Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a(+/-) hearts. The Journal of physiology, 2013, Sep-01, Volume: 591, Issue:17 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Flecainide; Heart Ventricles; Heterozygote; Male; Mice; Mutation; Myocardial Contraction; Myocardial Reperfusion; NAV1.5 Voltage-Gated Sodium Channel; Pericardium; Quinidine; Ventricular Function; Voltage-Gated Sodium Channel Blockers	2013
Effects of Na+ channel blockers on extrasystolic stimulation-evoked changes in ventricular conduction and repolarization. Journal of cardiovascular pharmacology, 2014, Volume: 63, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; Heart Ventricles; Lidocaine; Mexiletine; Quinidine; Sodium Channel Blockers; Tachycardia, Ventricular	2014
Effects of Na+ channel blockers on the restitution of refractory period, conduction time, and excitation wavelength in perfused guinea-pig heart. PloS one, 2017, Volume: 12, Issue:2 Topics: Action Potentials; Animals; Electrocardiography; Female; Flecainide; Guinea Pigs; Heart; Heart Conduction System; Heart Rate; Quinidine; Refractory Period, Electrophysiological; Voltage-Gated Sodium Channel Blockers	2017
Dynamic all-optical drug screening on cardiac voltage-gated ion channels. Scientific reports, 2018, 01-18, Volume: 8, Issue:1 Topics: Astemizole; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Flecainide; Gene Expression; HEK293 Cells; High-Throughput Screening Assays; Humans; Lidocaine; Membrane Potentials; NAV1.5 Voltage-Gated Sodium Channel; Optogenetics; Patch-Clamp Techniques; Phosphines; Plasmids; Potassium Channel Blockers; Quinidine; Voltage-Gated Sodium Channel Blockers	2018
Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals. PloS one, 2018, Volume: 13, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; In Vitro Techniques; Perfusion; Phenethylamines; Procainamide; Quinidine; Sulfonamides	2018
Treatment of recent-onset atrial fibrillation with quinidine and flecainide in Thoroughbred racehorses: 107 cases (1987-2014). Journal of the American Veterinary Medical Association, 2018, Jun-01, Volume: 252, Issue:11 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Flecainide; Horse Diseases; Horses; Male; Quinidine; Retrospective Studies	2018
Telemetered common marmosets is useful for the assessment of electrocardiogram parameters changes induced by multiple cardiac ion channel inhibitors. The Journal of toxicological sciences, 2019, Volume: 44, Issue:7 Topics: Animals; Astemizole; Body Temperature; Calcium Channel Blockers; Callithrix; Electrocardiography; Flecainide; Male; Models, Animal; Quinidine; Risk Assessment; Sotalol; Telemetry; Terfenadine; Verapamil; Voltage-Gated Sodium Channel Blockers	2019
Antiarrhythmic drug effects on premature beats are partly determined by prior cardiac activation frequency in perfused guinea-pig heart. Experimental physiology, 2020, Volume: 105, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Phenethylamines; Procainamide; Quinidine; Sulfonamides	2020
Electrocardiographic marker of the cardiac action potential triangulation induced by antiarrhythmic drugs in perfused guinea-pig heart. Experimental physiology, 2022, Volume: 107, Issue:8 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Flecainide; Guinea Pigs; Pericardium; Procainamide; Quinidine	2022
Pharmacological characterisation of electrocardiogram J-T European journal of pharmacology, 2022, Jul-15, Volume: 927 Topics: Animals; DNA-Binding Proteins; Electrocardiography; Flecainide; Guinea Pigs; Long QT Syndrome; Nifedipine; Quinidine; Quinine; Ranolazine; Sotalol; Torsades de Pointes; Verapamil	2022