quinidine has been researched along with digoxin in 430 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 314 (73.02) | 18.7374 |
| 1990's | 42 (9.77) | 18.2507 |
| 2000's | 39 (9.07) | 29.6817 |
| 2010's | 30 (6.98) | 24.3611 |
| 2020's | 5 (1.16) | 2.80 |
| Authors | Studies |
|---|---|
| Hirai, M; Hori, R; Kioka, N; Komano, T; Okamura, N; Tanigawara, Y; Ueda, K; Yasuhara, M | 1 |
| Fromm, MF; Kim, RB; Roden, DM; Stein, CM; Wilkinson, GR | 1 |
| Adachi, Y; Sugiyama, Y; Suzuki, H | 1 |
| Abe, T; Itoh, T; Kato, Y; Kusuhara, H; Meier, PJ; Shitara, Y; Sugiyama, D; Sugiyama, Y | 1 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Artursson, P; Neuhoff, S; Ungell, AL; Zamora, I | 1 |
| Thakker, DR; Troutman, MD | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Ebner, T; Ishiguro, N; Kishimoto, W; Schaefer, O; Shimizu, H | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R | 1 |
| Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
| Fishel, B; Herzberg, M; Wiener, MH | 1 |
| Donaldson, RM | 1 |
| Romankiewicz, JA | 1 |
| Altschuler, H; Cohen, HL; Escher, DJ; Fisher, JD; Furman, S; Mehra, R | 1 |
| Chapron, DJ; Mumford, D; Pitegoff, GI | 1 |
| Berman, ND | 1 |
| Fenster, P; Goldman, S; Graves, P; Hager, WD; Marcus, FI; Mayersohn, M; Perrier, D | 1 |
| Bigger, JT; Drusin, RE; Heissenbuttel, RH; Leahey, EB; Lovejoy, WP; Reiffel, JA | 2 |
| Doering, W | 2 |
| Milliken, JA | 1 |
| Burkle, WS; Matzke, GR | 1 |
| Jeffrey, LP; Rich, DS | 1 |
| Dahlqvist, R; Ejvinsson, G; Schenck-Gustafsson, K | 2 |
| Bigger, JT | 4 |
| Bigger, JT; Drusin, RE; Heissenbuttel, RH; Leahey, EB; Lovejoy, W; Reiffel, JA | 1 |
| Grabensee, B; Peters, U; Risler, T; Seipel, L | 3 |
| Wolf, PS | 1 |
| Meek, AG; Reid, PR | 1 |
| Hopkins, LE; Lee, M | 1 |
| Ashford, RF; Edmonds, ME; Hayler, AM; Holt, DW | 1 |
| Beitzke, A | 1 |
| Ejvinsson, G | 2 |
| Aldrich, JL; Castellanos, A; Maxwell, M; Myerburg, RJ; Sung, RJ | 1 |
| Jordan, J; Mandel, WJ; Yamaguchi, I | 1 |
| Aronow, WS; Danahy, DT | 1 |
| Doering, W; König, E | 2 |
| Hooymans, PM; Merkus, FW | 1 |
| Durrer, D | 1 |
| Crockatt, D; Okuno, T | 1 |
| Atik, E; Corradini, HB; Ebaid, M; Foronda, A | 1 |
| Cabana, BE | 1 |
| Downar, E; Waxman, MB | 1 |
| Gill, MA; Gourley, DR; Miscia, VF | 1 |
| Dreifus, L; Satinsky, JD | 1 |
| Amsterdam, EA; Mason, DT; Vismara, LA | 1 |
| Aranda, JM; Befeler, B; Castellanos, A; Moleiro, F | 1 |
| Heine, WI; Kollmann, GJ; Shapiro, B | 1 |
| Klein, G; Schinz, A; Schnelle, K | 1 |
| Charuk, J; De Lannoy, IA; Klein, J; Koren, G; Silverman, M | 1 |
| de Lannoy, IA; Silverman, M | 1 |
| Denisiuk, VI; Kotsuta, GI; Lipnitskiĭ, TN; Osiadlaia, ES; Pilipchuk, VP; Stepaniuk, AV | 1 |
| Glezer, MG; Orlov, LL; Tsintsadze, GI; Zaĭchik, IL | 1 |
| Hedman, A | 1 |
| Kamigaki, M; Lane, J; Mergener, MA; Murray, W; Williams, PJ | 1 |
| Candinas, R; Follath, F; Meyer, B | 1 |
| Ashavaid, TF; Colvin, RA; Katz, AM; Messineo, FC | 1 |
| Gu, F | 1 |
| Mazur, NA; Shestakova, NV | 1 |
| Angelin, B; Arvidsson, A; Dahlqvist, R; Hedman, A; Nilsson, B | 1 |
| Dvorský, J; Funiak, S; Kvĕtenský, J; Licko, V; Markuljak, I; Záhradný, V | 1 |
| Acheson, A; Goldstein, S; Landis, JR; Leighton, R; Moosvi, AR; Ritter, G; VanderBrug Medendorp, S; Vasu, CM; Wolfe, RA | 1 |
| Fulton, LJ; McKellar, CD; Stewart, GA | 1 |
| Hanig, JP; Thompson, TJ | 1 |
| Feld, GK; Nademanee, K; Noll, E; Singh, BN | 1 |
| Friedman, HS; Shah, S | 1 |
| Manito, N; Oriol, A; Roca, J | 1 |
| Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y | 2 |
| Lazor, JA; McNulty, RM; Sketch, M | 1 |
| Cepeláková, H; Hapala, J; Smíd, J; Topinka, I; Topolcan, O; Vainer, J | 1 |
| Jenkins, LC; Scoates, PJ | 1 |
| Yamaguchi, I | 1 |
| Abrams, WB; Rocci, ML; Vlasses, PH | 1 |
| Lees, KR; Rubin, PC | 1 |
| Hewick, DS; Ostenfeld, T | 1 |
| Hinohara, Y; Sakai, K; Yamazaki, T | 1 |
| Lodola, E; Ventresca, GP | 1 |
| Offerhaus, L | 2 |
| Dencker, L; Milton, A; Odlind, B | 1 |
| Akera, T; Berlin, JR; Brody, TM | 1 |
| Durkee, J; Hsu, PH; Lee, IK; Morganroth, J; Pool, PE; Salerno, DM; Somberg, JC | 1 |
| Gal, J; Molitoris, BA; Nakata, LM; Sedman, AJ | 1 |
| Morganroth, J; Nestico, PF | 1 |
| Angelin, B; Arvidsson, A; Dahlqvist, R; Hedman, A; Schenck-Gustafsson, K | 1 |
| Bach, P; Doliwa, R; Steinbeck, G | 1 |
| Ben Dayan, R; Giesbrecht, E; Klein, J; Koren, G; MacLeod, S; Sellers, E; Silverman, M; Soldin, S | 1 |
| Colucci, RD; Greenstein, RJ; Halpern, NA; Levy, E; McElhinney, AJ | 1 |
| Riley, CM | 1 |
| Jelliffe, RW | 2 |
| Adamski, M; Howlin, K; Jones, W; O'Neill, P; Quin, J; Stewart, G; Young, A | 1 |
| Hanano, M; Iga, T; Kurihara, A; Sawada, Y; Sugiyama, Y; Suzuki, H | 1 |
| Castellani, W; Chou, D; Galen, RS; Matzen, RN; Van Lente, F | 1 |
| Beekman, RH; Crowley, DC; Dick, M; Rocchini, AP; Rosenthal, A; Snider, AR; Spicer, RL; Webb, CL | 1 |
| Ilmurzyńska, K; Jachimowicz, J | 1 |
| Wilson, DD | 1 |
| Primm, RK; Roden, DM; Woosley, RL | 1 |
| Burckart, GJ; Marin-Garcia, J | 1 |
| Goldenberg, LM; Gordon, M | 1 |
| Gelband, H; Pickoff, AS; Stolfi, A | 1 |
| Beck, BL; Wilkerson, RD | 1 |
| Pedersen, KE | 2 |
| McGuirk, SM; Muir, WW | 2 |
| Strauss, HC; Wenger, TL | 1 |
| Stewart, PA; Wladimiroff, JW | 1 |
| Fossati, C | 1 |
| Piepho, RW | 1 |
| Barnard, JT; Bigger, JT; Warner, NJ | 1 |
| Gersh, BJ; Hammill, SC; Holmes, DR; Mair, DD; McLaran, C; Sugrue, DD | 1 |
| Rameis, H | 1 |
| Hobbins, JC; Kleinman, CS; Reece, EA; Romero, R; Santulli, T | 1 |
| Koren, G | 2 |
| Bren, GB; Gold, RL; Katz, RJ; Ross, AM; Varghese, PJ | 1 |
| Gibson, TP; O'Brien, MS; Salamone, LF | 1 |
| Bassan, HM; Ben-Itzhak, J; Lanir, A; Shor, R | 1 |
| Pitterle, ME; Sorkness, CA; Wiederholt, JB | 1 |
| Doering, W; Fichtl, B; Schäfer, SG; Schuhmann, G | 1 |
| Hill, BL; Tilley, LP | 1 |
| Dorph-Petersen, A | 1 |
| Basta, LL; Ehrenhaft, JL; Takeshita, A; Theilen, EO | 1 |
| Ferrer, MI | 1 |
| Barrillon, A; Gerbaux, A; Lenègre, J; Maurice, P | 1 |
| McGuire, J | 1 |
| Lamarche, M; Royer, R; Weiller, M | 1 |
| Doherty, JE; Kane, JJ | 1 |
| Kaiser, J; Schoelkens, B | 1 |
| Kritcher, EM; Luchi, RJ | 1 |
| Gotsman, MS; Pimstone, NR | 1 |
| Julian, DG | 1 |
| Manning, JA; Viles, PH | 1 |
| Laforet, EG | 1 |
| Warner, H | 1 |
| Smith, GH | 1 |
| Gaston, JH; Harrison, DC; Isaeff, DM | 1 |
| Craenen, J; Hosier, DM; Kilman, JW | 1 |
| Marion, DF; Terrien, CM | 1 |
| Cohen, SN; Doyle, EF; Rutkowski, MM | 1 |
| Andersen, ED; Jacobsen, JR; Sandoe, E; Videbaek, J; Wennevold, A | 1 |
| Anderson, WT; Cheitlin, MD; Golden, MS; Pinder, T | 1 |
| Tejani, N | 1 |
| Dreifus, LS | 1 |
| Artinian, B; Reesal, M | 1 |
| Fernandez, J; Fertig, H; Gooch, AS; Jan, MA; Maranhao, V; Morse, D | 1 |
| Forssell, G; Nordlander, R; Nyquist, O; Orinius, E | 1 |
| Gentzler, RD | 1 |
| Carrasco, H; Corday, E; Lang, TW; Lozano, J; Rubins, S | 1 |
| Berlinerblau, R; Feder, W | 1 |
| Christie, K; Cumming, GR; Sanchez, J | 1 |
| Cantwell, JD; Dawson, JE; Fletcher, GF | 1 |
| Behrer, RM; Goldring, D; Hernandez, A; Klint, RB | 1 |
| Guerricchio, G | 1 |
| Erickson, A | 1 |
| Langley, RB; Turner, AS; Wilson, DF | 1 |
| Cloup, M; Fidelle, J; Nouaille, J | 1 |
| Mah, GK | 1 |
| Donoso, E; Friedberg, CK; Lyon, LJ | 1 |
| Schollmeyer, P | 1 |
| Kretschmer, P; Selchau, M | 1 |
| Greenberg, HB; Hyman, AL | 1 |
| Oravetz, J; Slodki, SJ | 1 |
| Sapiński, A | 1 |
| Aberg, H; Cullhed, I | 1 |
| Greenberg, HB; Meyer, AD | 1 |
| Dick, HL; McCawley, EL; Reeves, M | 1 |
| Gorlin, R; Herman, MV; Sullivan, JM; Wolfson, S | 1 |
| Pruett, JK; Woods, EF | 1 |
| Escher, DJ; Furman, S; Solomon, N | 1 |
| Reid, JM; Stevenson, JC | 1 |
| Orgain, ES; Zipes, DP | 1 |
| Pyle, RL | 1 |
| Opie, LH | 2 |
| Schenck-Gustafsson, K | 1 |
| Grosse-Brockhoff, F | 1 |
| George, CF; Renwick, AG | 1 |
| Marcus, FI | 1 |
| Runge, M | 1 |
| Jozefczak, C; Le Fur, G; Mestre, M; Rougeot, C; Uzan, A | 1 |
| Ceci, V; Di Marcotullio, G; Dini, P; Milazzotto, F; Polizzi, C; Santini, M | 1 |
| Jahrmärker, H; Theisen, K | 1 |
| Chen, TS; Friedman, HS | 2 |
| Halawa, B; Mazurek, W | 2 |
| Belz, GG; Doering, W | 1 |
| Akera, T; Brody, TM; Kim, DH | 3 |
| Ball, WJ; Bilezikian, JP; Butler, VP; Schwartz, A; Tse-Eng, D; Wallick, ET | 1 |
| Bayer, R; Cohen, J; Henion, WA; Hilal, A; Montondo, D | 1 |
| Klitgaard, NA; Pedersen, KE | 1 |
| Bexton, RS; Camm, AJ | 1 |
| Hondeghem, LM; Mason, JW | 1 |
| Hancock, EW | 2 |
| Koren, G; MacLeod, SM | 1 |
| Flinn, GS; Marin-Garcia, J; Shaver, DC; Sibai, BM; Spinnato, JA; Watson, DL | 1 |
| Fujita, M; Ito, K; Owada, E; Yoshida, A | 1 |
| Dahlqvist, R; Jogestrand, T; Nordlander, R; Schenck-Gustafsson, K | 2 |
| Azzolini, P; Capurso, S | 1 |
| Risler, T; Seipel, L | 1 |
| Dyer, PD | 1 |
| Knox, SM; Miura, DS; Somberg, JC | 1 |
| Hanano, M; Iga, T; Sato, J; Sawada, Y | 1 |
| Koren, G; MacLeod, SM; Soldin, S | 1 |
| Collins-Nakai, RL; Ng, PK | 1 |
| Bussey, HI | 4 |
| Barr, CE; Carlson, J; Das, G | 1 |
| Bussey, HI; Hill, EG; Merritt, GJ | 1 |
| Barnard, JT; Bigger, JT; Hougen, TJ; Leahey, EB; Smith, TW; Warner, NJ | 1 |
| Blaschke, TF; Schulz, P | 1 |
| Fenster, PE; Goodman, MM; Hager, WD | 1 |
| Golitsyn, SP; Grosu, AA; Smetnev, AS; Sokolov, SF | 1 |
| Bigger, JT; Leahey, EB | 1 |
| Sato, T | 1 |
| Bisset, GS; James, FW; Kaplan, S; Meyer, RA; Schwartz, DC | 1 |
| Müller, FO; Steyn, JM | 1 |
| Achilli, A; Serra, N | 1 |
| Surawicz, B | 1 |
| Brodin, LA; Dahlqvist, R; Jogestrand, T; Nordlander, R; Schenck-Gustafsson, K | 1 |
| Christiansen, BD; Klitgaard, NA; Nielsen-Kudsk, F; Pedersen, KE | 2 |
| Scott, B | 1 |
| Danilo, P; Gessman, L; Rosen, MR | 1 |
| Cody, RJ; Greenblatt, DJ; Jick, H; Walker, AM | 1 |
| Bigger, JT; Hougen, TJ; Leahey, EB; Smith, TW; Warner, NJ | 1 |
| Doering, W; Fichtl, B; Seidel, H | 1 |
| Hair, TL; Taubert, KA | 1 |
| Dahlqvist, R; Juhlin-Dannfelt, A; Schenck-Gustafsson, K | 1 |
| Hunt, D; Manolas, EG; Sloman, G | 1 |
| Tonkin, A | 1 |
| Vlietstra, RE | 1 |
| Dahlgvist, R; Schenck-Gustafsson, K | 1 |
| Halwa, B | 1 |
| Stults, BM | 1 |
| Drake, CE | 1 |
| Besenfelder, E; Doering, W; Fichtl, B; Herrmann, M | 1 |
| Cheng, TO | 1 |
| Das, G | 1 |
| Dickstein, ES | 1 |
| Basseches, PJ; DiGregorio, GJ; Piraino, AJ; Ruch, EK | 1 |
| Barry, WH; Horowitz, JD; Smith, TW | 1 |
| Aust, PE; Belz, GG; Doering, W; Heinz, M; Matthews, J; Schneider, B | 1 |
| Doherty, JE | 1 |
| Clohisy, DR; Gibson, TP; Quintanilla, AP | 1 |
| Aust, PE; Belz, GG; Doering, W; Heinz, M; Schneider, B | 1 |
| Hefner, LL; Lash, RE; Reeves, DN; Reeves, RC | 1 |
| Fenster, PE; Graves, PE; Hager, WD; Michael, UF; Perrier, D; Powell, JR | 1 |
| Das, G; Geiger, JD; Parmar, SS | 1 |
| Kośmicki, M; Mamont, B | 1 |
| Ochs, HR | 1 |
| Soyka, LF | 1 |
| Conne, P; Grandjean, EM | 1 |
| Burelle, T; Hurst, D; Mungall, DR; Perry, W; Robichaux, RP; Robinson, A; Scott, JW | 1 |
| Leahey, EB | 1 |
| Fenster, PE; Hager, WD; Powell, JR | 1 |
| Doering, W; Fichtl, B | 1 |
| Dahlqvist, R; Schenck-Gustafsson, K | 1 |
| Buch, J; Egeblad, H; Hansen, PB; Kjaergaard, H; Steiness, E; Waldorff, S | 1 |
| Mathew, B; Williams, JF | 1 |
| Hirschberg, R; Kewitz, H; Kreutz, G; Schaefer, K; von Herrath, D | 1 |
| Affrime, MB; Lowenthal, DT | 1 |
| Marshall, J; Pieroni, RE | 1 |
| Ewy, GA; Fenster, PE | 1 |
| Doering, W; Höhne, M; Wagner, J | 1 |
| Graves, PE; Hager, WD; Mayersohn, M | 1 |
| Bigger, JT; Butler, VP; Leahey, EB; O'Connell, GC; Reiffel, JA; Rottman, JN; Scaffidi, LE | 1 |
| Achilli, A; Capezzuto, A; De Luca, F; Giacci, M; Guerra, R; Serra, N | 1 |
| Bodem, G; Greenblatt, DJ; Ochs, HR | 1 |
| Hartwig, W | 1 |
| Belpaire, F; De Rick, A | 1 |
| Lee, ST | 1 |
| Hvidt, S; Pedersen, KE | 1 |
| Straub, KD | 1 |
| Conrad, K; Fenster, PE; Graves, P; Hager, WD; Powell, JR; Wandell, M | 1 |
| Castellanos, A; Styperek, JL; Sung, RJ | 1 |
| Gibson, TP; Nelson, HA | 1 |
| Holford, NH | 2 |
| Moench, TR | 1 |
| Cieśliński, A; Grześkowiak, A; Ochotny, R; Wierzchowiecki, M | 1 |
| Hartzler, GO; Holmes, DR; Maloney, JD | 1 |
| Bonora, MR; Guaglio, R; Rondanelli, R; Terzoni, PA | 1 |
| Gebauerová, M; Málek, I; Stanĕk, V | 1 |
| Bissett, JK; de Soyza, N; Doherty, JE; Kane, JJ; Murphy, ML; Straub, KD | 1 |
| Massing, GK; Mockridge, PB; Wilkerson, RD | 1 |
| Abbott, JA; Cheitlin, MD; Desai, J; Holford, N; Peters, RW; Remedios, P; Scheinman, MM | 1 |
| Buch, J; Egeblad, H; Hansen, PB; Kjaergård, H; Steiness, E; Waldorff, S | 1 |
| Hastrup, J; Hvidt, S; Pedersen, KE | 1 |
| Bigger, JT; Giardina, EG; Leahey, EB; Reiffel, JA | 1 |
| Haustein, KO; Oltmanns, G | 1 |
| Halkin, H | 1 |
| Aladjem, M; Halkin, H; Kaplinsky, C; Laufer, J; Wolfish, N | 1 |
| Guggenheim, R; Reidenberg, MM | 1 |
| Hallam, CC; Noble, RJ; Steinmetz, EF | 1 |
| Gibson, TP; Quintanilla, A | 1 |
| Hirsh, PD; North, RL; Weiner, HJ | 1 |
| Bauernfeind, RA; Dhingra, RC; Palileo, E; Rosen, KM; Strasberg, B; Swiryn, SP; Wyndham, CR | 1 |
| Shapiro, W | 1 |
| Johnson, DE; Manyari, DE; Melendez, LJ; Patterson, C | 1 |
| Doherty, JE; Straub, KD | 1 |
| Bisset, GS; Gaum, WE; Kaplan, S; Seigel, SF | 1 |
| Kirikova, LT; Kostin, VI; Nesterov, IuI; Raevskaia, LG | 1 |
| Bebee, R; Freitag, D; Sunderland, B | 1 |
| Halinen, MO; Huttunen, M; Paakkinen, S; Tarssanen, L | 1 |
| Fernandez, IP; Herrera Carranza, J; Mac-Kay, MV; Sancez Burson, J | 1 |
| Blanc, JJ; Mansourati, J | 1 |
| Haberl, R; Knez, A; Steinbeck, G | 1 |
| Aiba, T; Hori, R; Okamura, N; Tanigawara, Y | 1 |
| Boriani, G; Capucci, A; Della Casa, S; Magnani, B; Rubino, I; Sanguinetti, M | 1 |
| Cowan, JC | 1 |
| Benson, DW; Deal, BJ; Müller, GI; Strasburger, JF | 1 |
| Almog, S; Ezra, D; Halkin, H; Mordel, A; Zulty, L | 1 |
| Faitel, K; Kerin, NZ; Naini, M | 1 |
| Camm, AJ; Sopher, SM | 1 |
| Kölbel, F; Schreiber, V | 1 |
| Cyr, DR; Guntheroth, WG; Nghiem, HV; Shields, LE | 1 |
| Huang, JD; Su, SF | 1 |
| Bauer, LA; Horn, JR; Pettit, H | 1 |
| Futterman, LG; Lemberg, L | 1 |
| Drake, CM; Kittleson, MD; Parraga, ME | 1 |
| Dillon, EC; Innes, GD; Metcalfe, C; Vertesi, L | 1 |
| Camm, AJ; Grace, AA | 1 |
| Ito, S; Koren, G; Woodland, C | 1 |
| Hedman, A; Meijer, DK | 2 |
| D'Andrea, A; Ducceschi, V; Iacono, A; Liccardo, B; Santangelo, L; Sarubbi, B | 1 |
| Halawa, B | 1 |
| Fromm, MF | 1 |
| Alvarez, AI; Kim, RB; Merino, G; Prieto, JG | 1 |
| Kakumoto, M; Kita, T; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y | 1 |
| Drescher, S; Eichelbaum, M; Fromm, MF; Glaeser, H; Hitzl, M; Mürdter, T | 1 |
| Mannesse, CK; van der Cammen, TJ | 1 |
| Ben-Zvi, Z; Holcberg, G; Huleihel, M; Katz, M; Lazer, S; Mazor, M; Sapir, O; Tsadkin, M | 1 |
| MCDONALD, L; O'BRIEN, K; RESNEKOV, L | 1 |
| DELMAN, AJ; STEIN, E | 1 |
| BEAULNES, A; BRODEUR, J | 1 |
| GUNTON, RW | 1 |
| SOWTON, E | 1 |
| READ, WO; WELTY, JD | 1 |
| ELLIS, CH | 1 |
| NEUFELD, HN; YAHINI, JH; ZAHAVI, I | 1 |
| ROBINSON, HJ; WAGNER, JA | 1 |
| LYON, AF; SHALAN, LJ | 1 |
| DE MONCHAUX, RJ | 1 |
| KATHE, JH; RODENSKY, PL; WASSERMAN, F | 1 |
| Benet, LZ; Lau, YY; Okochi, H; Wu, CY | 1 |
| Bulanova, NA; Kositsyna, IV; Morozova, MN; Tereshchenko, SN; Uteshev, IuA | 1 |
| Annaert, PP; Brouwer, KL | 1 |
| Chan, K; Jiang, ZH; Liu, L; Liu, ZQ; Wong, YF; Xu, HX; Zhou, H | 1 |
| Chung, FS; Endres, CJ; Hsiao, P; Unadkat, JD | 1 |
| Keogh, JP; Kunta, JR | 1 |
| Dirson, G; Farinotti, R; Fernandez, C; German-Fattal, M; Gimenez, F; Hindlet, P; Roux, F | 1 |
| Chiou, WL; Yao, HM | 1 |
| Jin, JS; Kakumoto, M; Nakamura, T; Nishiguchi, K; Okamura, N; Okumura, K; Sakaeda, T | 1 |
| Kawasaki, M; Langguth, P; Moriya, Y; Nakamura, T; Okumura, K; Omatsu, H; Sakaeda, T; Sakane, T; Shirasaka, Y; Yamashita, S | 1 |
| Asashi, S; Higuchi, T; Katoh, M; Suzuyama, N; Takeuchi, T; Yokoi, T; Yoshitomi, S | 1 |
| Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Liu, PQ; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW | 1 |
| Heikkinen, AT; Kemiläinen, H; Korjamo, T; Mönkkönen, J | 1 |
| Brenner, SS; Drescher, S; Eichelbaum, M; Fromm, MF; Glaeser, H; Heinkele, G; Hofmann, U; Igel, S; Mürdter, T; Omari, T; Schäfer, C; Somogyi, AA; Tegude, H | 1 |
| Acharya, P; Ayrton, A; Bentz, J; Ellens, H; O'Connor, MP; Polli, JW | 1 |
| Hirano, T; Iseki, K; Itagaki, S; Kobayashi, M; Ochiai, A; Sugawara, M | 1 |
| Anzai, N; Endou, H; Jutabha, P; Kadota, T; Otomo, J; Wempe, MF | 1 |
| Acharya, P; Ayrton, A; Bentz, J; Ellens, H; Lumen, AA; Polli, JW | 1 |
| Daubert, JP | 1 |
| Kochanowski, J; Kosior, DA; Opolski, G; Piatkowski, R; Postuła, M; Rabczenko, D; Scisło, P | 1 |
| Beale, KK; Bertino, JS; Ma, JD; Nafziger, AN; Trivedi, M; Tsunoda, SM | 1 |
| Baba, K; Hamahata, Y; Hayashi, M; Iwanaga, K; Kakemi, M; Miyazaki, M; Shibano, M; Taniguchi, M | 1 |
| Kawazu, K; Kiuchi, Y; Miyazaki, T; Oyabu, M; Toda, R | 1 |
| Abonyi, T; Beéry, E; Erdo, F; Fazakas, C; Herédi-Szabó, K; Kis, E; Krajcsi, P; Krizbai, I; Makai, I; Molnár, PM; Sziráki, I; Tóth, GK; Wilhelm, I | 1 |
| Li, P; Roberts, MS; Weiss, M | 1 |
| Amad, M; Batonga, J; Bethell, RC; Bolger, G; Cordingley, MG; Duan, J; Garneau, M; Jutras, M; Kukolj, G; Lapeyre, N; Montpetit, H; Otis, F; Rhéaume, M; White, PW | 1 |
| Kallem, R; Kulkarni, CP; Mahammad, SS; Mandlekar, S; Patel, D; Singh, SP; Sinz, M; Thakur, M | 1 |
| Ahmed, Z; Bentz, J; Ellens, H; Hidalgo, IJ; Li, J; Li, L; Lumen, AA; Meng, Z; Owen, A | 1 |
| Hu, ZY; Zhao, Y | 1 |
| Fricker, G; Gartzke, D | 1 |
| Enya, S; Kogayu, M; Komura, H; Nagao, A; Suzuki, M; Takubo, H; Yoshikawa, T | 1 |
| Fujii, S; Hosoya, K; Kawazu, K; Setoguchi, C | 1 |
| Akazawa, T; Ohtsuki, S; Tachikawa, M; Terasaki, T; Uchida, Y | 1 |
| Bentz, J; Ellens, H; Meng, Z | 1 |
| Murakami, T; Oda, K | 1 |
| Jin, H; Yang, S; Zhao, Z | 1 |
| Costales, C; Eatemadpour, S; Kimoto, E; Lazzaro, S; Varma, MV; Yamazaki, S | 1 |
| Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H | 1 |
| De Zwart, L; Evers, R; Yamazaki, S | 1 |
| Asaumi, R; Nunoya, KI; Sugiyama, Y; Taskar, KS; Yamaura, Y | 1 |
40 review(s) available for quinidine and digoxin
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The treatment of common cardiac arrhythmias.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Bradycardia; Digitalis Glycosides; Digoxin; Heart Block; Heart Ventricles; Humans; Infant; Isoproterenol; Lidocaine; Phenytoin; Potassium; Procainamide; Propranolol; Quinidine; Tachycardia; Tachycardia, Paroxysmal | 1976 |
[Mechanisms of interactions of anti-arrhythmia agents during their combined use].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Potassium; Procainamide; Propranolol; Quinidine; Verapamil | 1991 |
[Physiopathology of the transplanted heart. Review and clinical implications].
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Catecholamines; Coronary Circulation; Digoxin; Disopyramide; Dogs; Electrocardiography; Exercise Test; Follow-Up Studies; Heart; Heart Transplantation; Hemodynamics; Humans; Quinidine; Time Factors | 1989 |
Anaesthetic implications of calcium channel blockers.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Asthma; Calcium; Calcium Channel Blockers; Dantrolene; Digoxin; Drug Interactions; Esophagus; Humans; Hyperkalemia; Intracranial Pressure; Malignant Hyperthermia; Neuromuscular Blocking Agents; Quinidine; Theophylline; Vasoconstriction | 1985 |
[The interaction of antiarrhythmic drugs with other drugs].
Topics: Adrenergic beta-Agonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Digoxin; Drug Interactions; Humans; Lidocaine; Mexiletine; Phenytoin; Procainamide; Quinidine | 1985 |
Geriatric clinical pharmacology.
Topics: Adrenergic beta-Antagonists; Aged; Aging; Anti-Arrhythmia Agents; Biological Availability; Body Composition; Cardiovascular Agents; Digestive System Physiological Phenomena; Digoxin; Humans; Intestinal Absorption; Kidney; Kinetics; Liver; Pharmaceutical Preparations; Quinidine; Tissue Distribution | 1986 |
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil | 1986 |
Drug-receptor relationships, selection of therapeutic goals, and adaptive control of pharmacokinetic systems.
Topics: Aminoglycosides; Cardiac Output; Computer Simulation; Creatinine; Digoxin; Gentamicins; Humans; Kinetics; Lidocaine; Models, Biological; Quinidine; Receptors, Drug | 1987 |
Interactions between digitalis and antiarrhythmic drugs.
Topics: Anti-Arrhythmia Agents; Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Humans; Kinetics; Quinidine | 1985 |
[Pharmacologic interaction of amiodarone with other drugs].
Topics: Amiodarone; Benzofurans; Digoxin; Drug Interactions; Humans; Kinetics; Quinidine; Tachycardia | 1985 |
Digitalis toxicity.
Topics: Arrhythmias, Cardiac; Digitalis Glycosides; Digoxin; Drug Interactions; Humans; Myocardial Infarction; Quinidine | 1985 |
Individualization of calcium entry-blocker dosage for systemic hypertension.
Topics: Adult; Age Factors; Aged; Calcium Channel Blockers; Child; Cimetidine; Diabetes Complications; Digoxin; Drug Interactions; Female; Humans; Hypertension; Kidney Diseases; Kinetics; Lactation; Liver Diseases; Middle Aged; Pregnancy; Quinidine; Smoking | 1985 |
Pre-excitation syndrome: mechanisms and treatment.
Topics: Action Potentials; Cardiac Complexes, Premature; Digoxin; Electrocardiography; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Neural Pathways; Pacemaker, Artificial; Procainamide; Prognosis; Quinidine; Sinoatrial Node; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome | 1970 |
Clinical pharmacology and therapeutics use of digitalis glycosides.
Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Digitalis Glycosides; Digitoxin; Digoxin; Heart; Heart Failure; Heart Rate; Humans; Kidney Diseases; Kinetics; Lanatosides; Lidocaine; Myocardium; Pacemaker, Artificial; Phenytoin; Potassium; Procainamide; Propranolol; Quinidine; Thyroid Diseases | 1973 |
Recent advances in the treatment of congenital heart disease.
Topics: Age Factors; Arrhythmias, Cardiac; Child; Child, Preschool; Chlorothiazide; Diet, Sodium-Restricted; Digitalis Glycosides; Digoxin; Diuretics; Ethacrynic Acid; Furosemide; Heart Block; Heart Defects, Congenital; Heart Failure; Heart Septal Defects, Ventricular; Humans; Infant; Infant, Newborn; Organomercury Compounds; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tetralogy of Fallot; Transposition of Great Vessels | 1974 |
Therapy of common arrhythmias.
Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digitalis Glycosides; Digoxin; Fever; Heart Atria; Heart Block; Humans; Hypotension; Lung Diseases, Obstructive; Methoxamine; Pacemaker, Artificial; Procainamide; Propranolol; Pulmonary Embolism; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Ventricular Fibrillation | 1974 |
[Cardioactive agents. 49].
Topics: Aspartic Acid; Bufanolides; Cardanolides; Cardiac Glycosides; Digitoxin; Digoxin; Heart; Heart Diseases; Humans; Khellin; Lanatosides; Nitrites; Plants, Medicinal; Procainamide; Quinidine; Strophanthins; Sympatholytics; Sympathomimetics; Vasodilator Agents | 1970 |
[Therapy of arrhythmia during pregnancy].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biotransformation; Coumarins; Digoxin; Drug Synergism; Female; Fetal Growth Retardation; Fetus; Heparin; Humans; Infant, Newborn; Milk, Human; Pacemaker, Artificial; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Verapamil | 1984 |
[Medical treatment of extrasystole and tachycardia (author's transl)].
Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1980 |
Quinidine.
Topics: Animals; Arrhythmias, Cardiac; Digoxin; Drug Interactions; Electrocardiography; Heart Conduction System; Humans; Kinetics; Quinidine | 1984 |
Quinidine and digoxin. An important interaction.
Topics: Digoxin; Drug Interactions; Humans; Intestinal Absorption; Kidney; Myocardial Contraction; Quinidine | 1982 |
[Clinical pharmacology of digitalis glycosides].
Topics: Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Furosemide; Humans; Kinetics; Quinidine; Spironolactone; Vasodilator Agents | 1982 |
Pharmacokinetics of cardiovascular drugs.
Topics: Biological Availability; Cardiovascular Agents; Digoxin; Half-Life; Heart Diseases; Humans; Kinetics; Lidocaine; Models, Biological; Procainamide; Propranolol; Quinidine | 1980 |
[Quinidine-digoxin interaction-clinical therapy and pharmacokinetics].
Topics: Digoxin; Drug Interactions; Humans; Kinetics; Quinidine | 1980 |
[Digoxin: biological availability and interactions].
Topics: Anti-Arrhythmia Agents; Anticholesteremic Agents; Biological Availability; Digoxin; Drug Interactions; Humans; Intestinal Absorption; Neomycin; Quinidine | 1981 |
Digoxin use in the elderly.
Topics: Adult; Age Factors; Aged; Atrial Fibrillation; Digoxin; Diuretics; Drug Interactions; Half-Life; Heart Conduction System; Heart Failure; Heart Ventricles; Humans; Middle Aged; Monitoring, Physiologic; Patient Compliance; Quinidine | 1982 |
The quinidine--digoxin interaction.
Topics: Animals; Anti-Arrhythmia Agents; Binding, Competitive; Cattle; Digitalis Glycosides; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Humans; Kinetics; Quinidine; Time Factors | 1981 |
The influence of quinidine and other agents on digitalis glycosides.
Topics: Anti-Arrhythmia Agents; Digitalis Glycosides; Digitoxin; Digoxin; Diuretics; Drug Interactions; Glomerular Filtration Rate; Humans; Metabolic Clearance Rate; Quinidine; Tissue Distribution | 1982 |
[Can atrial fibrillation be managed without anti-arrhythmia drugs?].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Digoxin; Double-Blind Method; Drug Therapy, Combination; Electric Countershock; Female; Follow-Up Studies; Heart Rate; Humans; Male; Quinidine | 1994 |
Atrial fibrillation: maintenance of sinus rhythm versus rate control.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Calcium Channel Blockers; Catheter Ablation; Digoxin; Electric Countershock; Flecainide; Heart Failure; Heart Rate; Heart Ventricles; Humans; Quinidine; Sinoatrial Node; Thromboembolism; Time Factors | 1996 |
Three autacoids--endogenous digitalis-like factor, clonidine-displacing substance, and quinidine-like immunoreactivity.
Topics: Animals; Autacoids; Cardenolides; Clonidine; Digoxin; Enzyme Inhibitors; Humans; Quinidine; Saponins | 1995 |
Atrial fibrillation: an increasingly common and provocative arrhythmia.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Electric Countershock; Female; Humans; Myocardial Infarction; Quinidine | 1996 |
Quinidine.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Clinical Trials as Topic; Digoxin; Drug Interactions; Electrophysiology; Heart; Humans; Potassium Channels; Quinidine; Sodium Channels | 1998 |
Toxic digoxin-drug interactions: the major role of renal P-glycoprotein.
Topics: Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cyclosporine; Digoxin; Drug Interactions; Glomerular Filtration Rate; Humans; Itraconazole; Kidney Tubules; Quinidine; Verapamil | 1998 |
Atrial fibrillation: what are the effects of drug therapy on the effectiveness and complications of electrical cardioversion?
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Digoxin; Electric Countershock; Flecainide; Humans; Procainamide; Quinidine; Verapamil | 1998 |
[Chronic heart failure and atrial fibrilation: aspects of management].
Topics: Acute Disease; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Cardiotonic Agents; Clinical Trials as Topic; Digoxin; Electric Countershock; Heart Failure; Humans; Quinidine; Randomized Controlled Trials as Topic; Sotalol; Sympatholytics; Time Factors; Vasodilator Agents | 2003 |
The role of transporters in drug interactions.
Topics: Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Digoxin; Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; In Vitro Techniques; Kidney; Liver; Membrane Transport Proteins; Models, Biological; Organic Anion Transporters; Organic Cation Transport Proteins; Quinidine | 2006 |
Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Drug Interactions; Genotype; Humans; Pharmacogenetics; Phenotype; Polymorphism, Single Nucleotide; Prescription Drugs; Propanolamines; Quinidine; Reproducibility of Results; Terfenadine | 2010 |
17 trial(s) available for quinidine and digoxin
| Article | Year |
|---|---|
Antazoline therapy of recurrent refractory supraventricular arrhythmias--a preliminary report.
Topics: Adolescent; Adult; Aged; Antazoline; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Digoxin; Drug Evaluation; Female; Humans; Imidazoles; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Recurrence | 1975 |
Oral N-acetylprocainamide compared to quinidine plus digoxin in the chronic suppression of atrial flutter in humans.
Topics: Acecainide; Action Potentials; Aged; Atrial Flutter; Digoxin; Drug Therapy, Combination; Humans; Male; Middle Aged; Quinidine; Random Allocation | 1989 |
Comparative study of encainide and quinidine in the treatment of ventricular arrhythmias.
Topics: Adult; Aged; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Digoxin; Double-Blind Method; Drug Interactions; Electrocardiography; Encainide; Female; Humans; Male; Middle Aged; Quinidine; Random Allocation | 1986 |
[Therapy of paroxysmal atrial fibrillation. Cardiac glycosides alone or combined with anti-arrhythmia agents?].
Topics: Administration, Oral; Aged; Atrial Fibrillation; Clinical Trials as Topic; Digoxin; Drug Therapy, Combination; Female; Flecainide; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Random Allocation; Time Factors | 1988 |
Quinidine-digoxin interaction: are the pharmacokinetics of both drugs altered?
Topics: Acetyldigoxins; Adult; Digoxin; Drug Interactions; Humans; Male; Metabolic Clearance Rate; Quinidine | 1985 |
Effect of coadministration of verapamil and quinidine on serum digoxin concentration.
Topics: Adult; Digoxin; Drug Combinations; Drug Interactions; Electrocardiography; Heart Rate; Humans; Middle Aged; Quinidine; Verapamil | 1983 |
Effects of quinidine and disopyramide on serum digoxin concentrations.
Topics: Adult; Aged; Arrhythmias, Cardiac; Digoxin; Disopyramide; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pyridines; Quinidine; Syncope | 1980 |
Quinidine-digoxin interaction: cardiac efficacy of elevated serum digoxin concentration.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Output; Digoxin; Drug Interactions; Electrocardiography; Heart; Hemodynamics; Humans; Male; Quinidine | 1982 |
Pharmacodynamics of a single dose of quinidine during chronic digoxin treatment. A randomized double blind placebo and sparteine--controlled crossover study.
Topics: Adult; Blood Pressure; Digoxin; Double-Blind Method; Drug Interactions; Electrocardiography; Heart Rate; Hemodynamics; Humans; Male; Placebos; Quinidine; Random Allocation; Sparteine | 1982 |
Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).
Topics: Acute Disease; Adult; Aged; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Quinidine; Sotalol; Tachycardia; Time Factors | 1995 |
[The use of digitalis glycosides in atrial fibrillation].
Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Digoxin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Tachycardia, Paroxysmal | 1994 |
A controlled study on oral propafenone versus digoxin plus quinidine in converting recent onset atrial fibrillation to sinus rhythm.
Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Digoxin; Drug Combinations; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Placebos; Propafenone; Quinidine; Remission Induction; Single-Blind Method; Ventricular Function | 1994 |
The efficacy of intravenous amiodarone for the conversion of chronic atrial fibrillation. Amiodarone vs quinidine for conversion of atrial fibrillation.
Topics: Administration, Oral; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Digoxin; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Quinidine; Treatment Outcome | 1996 |
Mixed-effect modeling for detection and evaluation of drug interactions: digoxin-quinidine and digoxin-verapamil combinations.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anti-Arrhythmia Agents; Body Weight; Calcium Channel Blockers; Computer Simulation; Creatinine; Digoxin; Drug Combinations; Drug Interactions; Female; Humans; Male; Middle Aged; Models, Biological; Quinidine; Regression Analysis; Verapamil | 1996 |
Effectiveness of verapamil-quinidine versus digoxin-quinidine in the emergency department treatment of paroxysmal atrial fibrillation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Double-Blind Method; Drug Therapy, Combination; Emergency Medical Services; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Tachycardia, Paroxysmal; Treatment Outcome; Verapamil | 1997 |
Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport, Active; Digoxin; Enterocytes; Enzyme Inhibitors; Epithelial Cells; Humans; Intestinal Absorption; Jejunum; Male; Protein Transport; Quinidine; Xenobiotics | 2007 |
Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Digoxin; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Heart Conduction System; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Propafenone; Prospective Studies; Quinidine; Recurrence; Time Factors; Treatment Outcome | 2009 |
373 other study(ies) available for quinidine and digoxin
| Article | Year |
|---|---|
Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Digoxin; Drug Interactions; Gene Expression; Humans; Kidney Tubules; Membrane Glycoproteins; Quinidine; Swine; Transfection; Verapamil | 1992 |
Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments].
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Cardiovascular Agents; Digoxin; Drug Interactions; Drug Resistance, Multiple; Humans; Mice; Quinidine; Tissue Distribution | 1999 |
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection | 2001 |
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antimalarials; Biological Transport, Active; Digoxin; Enzyme Inhibitors; Estradiol; Ibuprofen; LLC-PK1 Cells; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Quinidine; Quinine; Rats; Rifampin; Swine | 2002 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Digoxin; Drug Interactions; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Pharmaceutical Preparations; Pharmacokinetics | 2003 |
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2003 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Base Sequence; Dipeptidyl-Peptidase IV Inhibitors; DNA Primers; Drug Evaluation, Preclinical; Drug Interactions; HEK293 Cells; Humans; In Vitro Techniques; Linagliptin; LLC-PK1 Cells; Purines; Quinazolines; Swine | 2013 |
Development of an
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic | 2021 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
Hepatic microsomal enzyme induction and its evaluation in a clinical laboratory.
Topics: Adult; Aged; Diazepam; Digoxin; Enzyme Induction; Female; Furosemide; gamma-Glutamyltransferase; Glucaric Acid; Humans; Male; Methyldopa; Microsomes, Liver; Middle Aged; Quinidine | 1977 |
The treatment of supraventricular arrhythmias.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Digoxin; Disopyramide; Electric Countershock; Humans; Phenytoin; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1979 |
Effects of antacids on gastrointestinal absorption of drugs.
Topics: Animals; Antacids; Aspirin; Chlordiazepoxide; Chlorpromazine; Dicumarol; Digitoxin; Digoxin; Ephedrine; Guinea Pigs; Humans; Intestinal Absorption; Iron; Isoniazid; Levodopa; Naproxen; Pentobarbital; Pharmaceutical Preparations; Quinidine; Quinine; Rats; Sulfadiazine; Tetracyclines; Warfarin | 1976 |
Cardiac pacing and pacemakers II. Serial electrophysiologic-pharmacologic testing for control of recurrent tachyarrhythmias.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Bretylium Compounds; Cardiac Complexes, Premature; Digoxin; Edrophonium; Electrocardiography; Female; Heart; Heart Ventricles; Humans; Male; Middle Aged; Pacemaker, Artificial; Phenytoin; Procainamide; Propantheline; Propranolol; Pyridostigmine Bromide; Quinidine; Recurrence; Tachycardia | 1977 |
Apparent quinidine-induced digoxin toxicity after withdrawal of pentobarbital: a case of sequential drug interactions.
Topics: Aged; Atrial Fibrillation; Digoxin; Drug Interactions; Female; Half-Life; Humans; Liver; Pentobarbital; Quinidine; Sleep Wake Disorders | 1979 |
The elderly patient in the coronary care unit. II. Incidence and treatment of arrhythmias.
Topics: Aged; Arrhythmias, Cardiac; Atropine; Cardiac Pacing, Artificial; Coronary Care Units; Digoxin; Electric Countershock; Electrocardiography; Female; Humans; Lidocaine; Male; Myocardial Infarction; Ontario; Procainamide; Propranolol; Quinidine | 1979 |
Digoxin-quinidine interaction Pharmacokinetic evaluation.
Topics: Digoxin; Drug Interactions; Half-Life; Humans; Quinidine | 1979 |
Drugs in the elderly.
Topics: Aged; Analgesics; Anti-Bacterial Agents; Anticoagulants; Antihypertensive Agents; Digoxin; Diuretics; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypnotics and Sedatives; Male; Psychotropic Drugs; Quinidine; Theophylline | 1979 |
Enhanced cardiac effect of digoxin during quinidine treatment.
Topics: Aged; Aortic Valve Stenosis; Arrhythmias, Cardiac; Digoxin; Drug Synergism; Female; Heart; Hemodynamics; Humans; Male; Middle Aged; Quinidine | 1979 |
Quinidine-digoxin interaction: Pharmacokinetics, underlying mechanism and clinical implications.
Topics: Adult; Aged; Animals; Binding Sites; Digoxin; Drug Interactions; Female; Humans; Kidney; Male; Middle Aged; Myocardium; Quinidine; Sarcolemma; Sheep | 1979 |
Interactions of digitalis.
Topics: Arrhythmias, Cardiac; Barbiturates; Digitalis Glycosides; Digitoxin; Digoxin; Diuretics; Drug Interactions; Humans; Hypokalemia; Phenylbutazone; Potassium; Quinidine | 1979 |
Effect of quinidine on serum digoxin concentrations.
Topics: Aged; Atrial Fibrillation; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Quinidine | 1979 |
Quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1979 |
Digoxin-quinidine interaction.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1979 |
The quinidine-digoxin interaction: what do we know about it?
Topics: Animals; Anti-Arrhythmia Agents; Binding Sites; Cattle; Digoxin; Drug Interactions; Heart; Humans; Myocardium; Quinidine | 1979 |
A previously unrecognized drug interaction between quinidine and digoxin.
Topics: Adult; Aged; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Male; Middle Aged; Quinidine; Retrospective Studies | 1979 |
[Interaction of quinidine and digoxin in humans (author's transl)].
Topics: Digoxin; Drug Interactions; Glomerular Filtration Rate; Humans; Male; Quinidine | 1979 |
Arrhythmias in chronic pulmonary disease.
Topics: Arrhythmias, Cardiac; Chronic Disease; Digoxin; Humans; Hypokalemia; Hypoxia; Lidocaine; Lung Diseases; Oxygen Inhalation Therapy; Procainamide; Propranolol; Pulmonary Atelectasis; Quinidine | 1979 |
Digoxin -- quinidine interaction.
Topics: Atrial Fibrillation; Digoxin; Drug Synergism; Drug Therapy, Combination; Humans; Male; Middle Aged; Quinidine | 1979 |
Management of quinidine-induced elevations of serum digoxin.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1979 |
Clinically significant interaction between digoxin and quinidine.
Topics: Aged; Coronary Disease; Digoxin; Drug Interactions; Female; Humans; Lung Diseases, Obstructive; Male; Pulmonary Heart Disease; Quinidine | 1979 |
[Multifocal (chaotic) atrial tachycardia in infancy].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Electrocardiography; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Propranolol; Quinidine; Tachycardia; Tachycardia, Paroxysmal | 1979 |
Effect of quinidine on plasma concentrations of digoxin.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1978 |
Electrocardiographic manifestations and clinical significance of atrioventricular nodal alternating Wenckbach periods.
Topics: Acute Disease; Atrial Flutter; Atrioventricular Node; Bundle of His; Digitalis Glycosides; Digoxin; Electrocardiography; Heart Atria; Heart Block; Heart Conduction System; Heart Diseases; Humans; Myocardial Infarction; Pacemaker, Artificial; Purkinje Fibers; Quinidine; Tachycardia | 1978 |
Elimination of the delta wave in the Wolff-Parkinson-White syndrome. A misleading indicator of therapeutic effectiveness.
Topics: Aged; Atrioventricular Node; Bundle of His; Cardiac Pacing, Artificial; Digoxin; Electrocardiography; Female; Humans; Quinidine; Tachycardia; Wolff-Parkinson-White Syndrome | 1978 |
Lidocaine-induced cardiac rate changes in atrial fibrillation and atrial flutter.
Topics: Adult; Aged; Atrial Fibrillation; Atrial Flutter; Digoxin; Drug Interactions; Electrocardiography; Heart Rate; Heart Ventricles; Humans; Lidocaine; Middle Aged; Potassium; Quinidine | 1978 |
Interaction between quinidine and digoxin.
Topics: Aged; Anorexia; Arrhythmias, Cardiac; Digoxin; Drug Interactions; Female; Humans; Male; Middle Aged; Nausea; Quinidine; Vomiting | 1978 |
[The influence of quinidine on serum digoxin concentrations (author's transl)].
Topics: Digoxin; Drug Synergism; Drug Therapy, Combination; Humans; Quinidine | 1978 |
Effect of quinidine on plasma concentration of digoxin.
Topics: Digoxin; Drug Combinations; Drug Interactions; Humans; Quinidine | 1978 |
Quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Methods; Quinidine | 1979 |
Medical and surgical treatment of the Wolff-Parkinson-White syndrome.
Topics: Digoxin; Humans; Methods; Procainamide; Propranolol; Quinidine; Secologanin Tryptamine Alkaloids; Wolff-Parkinson-White Syndrome | 1976 |
Anti-drug-related antibodies in nonthrombocytopenic cardiac patients.
Topics: Adult; Aged; Antibodies; Blood Platelets; Chromium Radioisotopes; Digoxin; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Platelet Factor 3; Purpura, Thrombocytopenic; Quinidine | 1976 |
[Congenital atrial flutter. Report of a case with immediate reversal to normal rhythm after drug therapy].
Topics: Atrial Flutter; Digoxin; Heart Rate; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Quinidine | 1976 |
Importance of biopharmaceutics and pharmacokinetics in clinical medicine.
Topics: Animals; Anti-Bacterial Agents; Biological Availability; Biopharmaceutics; Digoxin; Dosage Forms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Half-Life; Humans; In Vitro Techniques; Kinetics; Nitrofurantoin; Pharmaceutical Preparations; Quinidine; Therapeutic Equivalency | 1976 |
Drugs of choice for atrial tachycardia.
Topics: Administration, Oral; Digitalis Glycosides; Digoxin; Edrophonium; Humans; Lanatosides; Metaraminol; Neostigmine; Parasympathomimetics; Propranolol; Quinidine; Tachycardia; Verapamil | 1975 |
Relation of ventricular arrhythmias in the late hospital phase of acute myocardial infarction to sudden death after hospital discharge.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Aspartate Aminotransferases; Creatine Kinase; Death, Sudden; Digoxin; Diuretics; Female; Follow-Up Studies; Heart Failure; Hospitalization; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Myocardial Infarction; Potassium; Procainamide; Quinidine; Sodium; Time Factors | 1975 |
Electrophysiologic studies in a patient with atrial flutter and 1:1 atrioventricular conduction.
Topics: Adult; Atrial Flutter; Atrioventricular Node; Cardiac Catheterization; Digoxin; Electric Stimulation; Electrocardiography; Electrophysiology; Heart Conduction System; Humans; Male; Ouabain; Quinidine | 1975 |
Pitfalls in the application of digoxin determinations.
Topics: Administration, Oral; Aged; Biopharmaceutics; Calcium; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Hypothyroidism; Hypoxia; Kidney Failure, Chronic; Magnesium; Male; Middle Aged; Potassium; Procainamide; Propranolol; Quinidine; Radioimmunoassay | 1975 |
[Proceedings: Value of plasma level determinations of cardioactive drugs during therapy].
Topics: Digoxin; Drug Therapy; Humans; Quinidine; Sotalol | 1975 |
Cyclosporin and quinidine inhibition of renal digoxin excretion: evidence for luminal secretion of digoxin.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Digoxin; Dogs; Female; Kidney; Male; Membrane Glycoproteins; Ouabain; Quinidine | 1992 |
The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Resistance; Kinetics; Membrane Glycoproteins; Quinidine; Verapamil; Vinblastine | 1992 |
[Clinical effectiveness of cordarone in combination with other anti-arrhythmia agents in refractory atrial fibrillation and adverse effects of the drugs].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Humans; Middle Aged; Moricizine; Quinidine; Verapamil | 1992 |
[The effect of quinidine monotherapy and combined therapy with digoxin on the central hemodynamics in patients with heart rhythm disorders].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digoxin; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Middle Aged; Quinidine; Time Factors | 1992 |
Inhibition by basic drugs of digoxin secretion into human bile.
Topics: Bile; Chromatography, High Pressure Liquid; Digoxin; Drug Interactions; Humans; Probenecid; Quinidine; Quinine; Radioimmunoassay; Spironolactone; Verapamil | 1992 |
Pharmacokinetics of the digoxin-quinidine interaction via mixed-effect modelling.
Topics: Adult; Aged; Aged, 80 and over; Biological Availability; Body Constitution; Creatinine; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Heart Failure; Humans; Kidney; Male; Middle Aged; Models, Biological; Quinidine | 1992 |
[Drug therapy in supraventricular arrhythmia].
Topics: Amiodarone; Anti-Arrhythmia Agents; Digoxin; Flecainide; Humans; Quinidine; Tachycardia, Supraventricular | 1992 |
Amiodarone, verapamil, and quinidine do not affect equilibrium binding of digoxin.
Topics: Amiodarone; Animals; Binding, Competitive; Digoxin; Dogs; Myocardium; Quinidine; Receptors, Drug; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Verapamil | 1990 |
[A study on monitoring blood level of quinidine in converting atrial fibrillation].
Topics: Adult; Aged; Atrial Fibrillation; Digoxin; Drug Incompatibility; Drug Monitoring; Female; Humans; Male; Middle Aged; Quinidine; Rheumatic Heart Disease | 1991 |
Interactions in the renal and biliary elimination of digoxin: stereoselective difference between quinine and quinidine.
Topics: Adult; Bile; Digoxin; Duodenum; Humans; Kidney Tubules; Liver; Male; Perfusion; Quinidine; Quinine; Stereoisomerism | 1990 |
[The effect of quinidine on digoxin plasma levels after discontinuation of digoxin therapy].
Topics: Arrhythmias, Cardiac; Digoxin; Drug Interactions; Female; Humans; Male; Middle Aged; Quinidine | 1990 |
Effect of empiric antiarrhythmic therapy in resuscitated out-of-hospital cardiac arrest victims with coronary artery disease.
Topics: Aged; Anti-Arrhythmia Agents; Coronary Disease; Death, Sudden; Digoxin; Heart Arrest; Humans; Middle Aged; Procainamide; Quinidine; Resuscitation; Retrospective Studies | 1990 |
Idiopathic atrial fibrillation in a champion Standardbred racehorse.
Topics: Animals; Atrial Fibrillation; Digoxin; Electrocardiography; Horse Diseases; Horses; Male; Quinidine | 1990 |
Quinidine enhancement of digoxin toxicity in rats and minipigs.
Topics: Anesthesia; Animals; Blood Pressure; Digoxin; Electrocardiography; Heart Rate; Male; Quinidine; Rats; Swine; Swine, Miniature; Time Factors | 1989 |
The relation of quinidine-induced elevation of serum digoxin concentration to the conversion of atrial fibrillation-flutter: a pilot study.
Topics: Atrial Fibrillation; Atrial Flutter; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Pilot Projects; Quinidine | 1989 |
Effect of quinidine on the hepatic uptake of digoxin in guinea pigs.
Topics: Animals; Diazepam; Digoxin; Guinea Pigs; In Vitro Techniques; Indicator Dilution Techniques; Liver; Ouabain; Quinidine; Temperature | 1989 |
Transient increase in plasma quinidine concentrations during ketoconazole-quinidine therapy.
Topics: Aged; Candidiasis; Creatinine; Digoxin; Drug Interactions; Humans; Ketoconazole; Leukemia, Myeloid, Acute; Male; Quinidine; Time Factors | 1989 |
[Pharmacologic restoration of sinus rhythm in atrial flutter and fibrillation].
Topics: Atrial Fibrillation; Atrial Flutter; Digoxin; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Quinidine; Verapamil | 1989 |
Effect of quinidine on the tissue binding of digoxin in guinea-pigs.
Topics: Adenosine Triphosphate; Animals; Digoxin; Drug Interactions; Guinea Pigs; In Vitro Techniques; Liver; Male; Muscles; Myocardium; Quinidine; Tissue Distribution | 1986 |
Treatment of cardiovascular diseases.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Digoxin; Female; Humans; Lidocaine; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Quinidine | 1987 |
The effect of digoxin dosage on the digoxin-quinidine interaction in the bile duct-cannulated rat.
Topics: Animals; Bile; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Intestinal Secretions; Kinetics; Quinidine; Rats; Rats, Inbred Strains; Tissue Distribution | 1987 |
Effects of AN-132 and quinidine, antiarrhythmic agents, on plasma digoxin concentrations in rats.
Topics: Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Digoxin; Drug Interactions; Ethylenediamines; Male; Quinidine; Rats; Rats, Inbred Strains | 1988 |
Clinical pharmacokinetics of ibopamine on different diseases and conditions.
Topics: Absorption; Administration, Oral; Adult; Aged; Aged, 80 and over; Biological Availability; Chemical Phenomena; Chemistry; Deoxyepinephrine; Digoxin; Dopamine; Dopamine Agents; Drug Interactions; Female; Food; Heart Failure; Humans; Kidney Failure, Chronic; Liver Cirrhosis; Male; Middle Aged; Quinidine; Vasodilator Agents | 1988 |
Cardiac glycoside interactions at 'silent' and at active receptors. Putative biochemical backgrounds and possible clinical relevance.
Topics: Animals; Brain; Digoxin; Drug Interactions; Enzyme Activation; Erythrocyte Membrane; Humans; In Vitro Techniques; Myocardium; Quinidine; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Swine; Thyroxine; Triiodothyronine | 1985 |
Renal handling and effects of [3H]digoxin and interactions with quinidine in the avian kidney.
Topics: Animals; Autoradiography; Biological Transport, Active; Digoxin; Drug Interactions; Female; Inulin; Kidney; Kidney Tubules; Natriuresis; Poultry; Quinidine; Sodium-Potassium-Exchanging ATPase | 1986 |
Lack of pharmacodynamic interactions between quinidine and digoxin in isolated atrial muscle of guinea pig heart.
Topics: Action Potentials; Animals; Benzocaine; Digoxin; Drug Interactions; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Ouabain; Quinidine; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin | 1986 |
Quinidine reduces biliary clearance of digoxin in man.
Topics: Aged; Bile; Digoxin; Drug Interactions; Female; Humans; Kidney; Male; Metabolic Clearance Rate; Middle Aged; Quinidine | 1987 |
Effects of quinidine on the renal tubular and biliary transport of digoxin: in vivo and in vitro studies in the dog.
Topics: Animals; Bile; Biological Transport; Digoxin; Dogs; In Vitro Techniques; Kidney Tubules; Metabolic Clearance Rate; Microvilli; Quinidine | 1988 |
The effect of various postphlebotomy storage conditions on drug levels.
Topics: Animals; Bloodletting; Digoxin; Dogs; Pharmaceutical Preparations; Quinidine | 1988 |
Stability of milrinone and digoxin, furosemide, procainamide hydrochloride, propranolol hydrochloride, quinidine gluconate, or verapamil hydrochloride in 5% dextrose injection.
Topics: Digoxin; Drug Combinations; Drug Stability; Drug Storage; Furosemide; Glucose; Indicators and Reagents; Milrinone; Procainamide; Propranolol; Pyridones; Quinidine; Solutions; Temperature; Verapamil | 1988 |
Quinidine-induced allergic granulomatous angiitis: an unusual cause of acute renal failure.
Topics: Acute Kidney Injury; Digoxin; Drug Therapy, Combination; Eosinophilia; Granuloma; Humans; Male; Middle Aged; Quinidine; Vasculitis, Leukocytoclastic, Cutaneous | 1988 |
Transport of digoxin into brain microvessels and choroid plexuses isolated from guinea pig.
Topics: Animals; Brain; Choroid Plexus; Digoxin; Guinea Pigs; In Vitro Techniques; Male; Microcirculation; Ouabain; Quinidine | 1988 |
Application of the EXPERT consultation system to accelerated laboratory testing and interpretation.
Topics: Adolescent; Adult; Aged; Artificial Intelligence; Bilirubin; Blood Glucose; Chemistry Techniques, Analytical; Diagnosis, Computer-Assisted; Digoxin; Female; Gilbert Disease; Hemoglobins; Hemolysis; Humans; Laboratories; Liver; Male; Middle Aged; Quinidine; Theophylline; Thyroxine | 1986 |
Quinidine syncope in children.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Child; Child, Preschool; Digitoxin; Digoxin; Drug Administration Schedule; Electrocardiography; Heart Diseases; Hemodynamics; Humans; Quinidine; Syncope | 1987 |
[Influence of quinidine administration on the concentration of digoxin in blood serum].
Topics: Adult; Aged; Digoxin; Drug Interactions; Humans; Middle Aged; Quinidine | 1987 |
Clinical applications of pharmacokinetics and adaptive control.
Topics: Biomedical Engineering; Digoxin; Feedback; Gentamicins; Humans; Infusion Pumps; Lidocaine; Models, Biological; Pharmaceutical Preparations; Quinidine | 1987 |
What's wrong with this patient?
Topics: Aged; Digoxin; Female; Heart Failure; Humans; Quinidine | 1987 |
Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Digoxin; Electrocardiography; Female; Heart Ventricles; Humans; Long QT Syndrome; Male; Middle Aged; Potassium; Quinidine; Tachycardia | 1986 |
Quinidine dosage in children using population estimates.
Topics: Adolescent; Arrhythmias, Cardiac; Body Surface Area; Body Weight; Child; Child, Preschool; Digoxin; Humans; Infant; Infant, Newborn; Quinidine; Regression Analysis; Retrospective Studies | 1986 |
Clinical digoxin toxicity in the aged in association with co-administered verapamil. A report of two cases and review of the literature.
Topics: Aged; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Kinetics; Quinidine; Verapamil | 1986 |
Digoxin-quinidine interaction in the neonatal dog.
Topics: Animals; Animals, Newborn; Digoxin; Dogs; Drug Interactions; Quinidine; Tissue Distribution | 1986 |
Increase in serum digoxin concentration produced by quinidine does not increase the potential for digoxin-induced ventricular arrhythmias in dogs.
Topics: Animals; Arrhythmias, Cardiac; Digoxin; Dogs; Drug Interactions; Quinidine; Strophanthidin | 1987 |
Digoxin interactions. The influence of quinidine and verapamil on the pharmacokinetics and receptor binding of digitalis glycosides.
Topics: Animals; Digitalis Glycosides; Digoxin; Drug Interactions; Humans; Kinetics; Quinidine; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Verapamil | 1985 |
Pharmacology and pharmacokinetics of drugs used to treat cardiac disease in horses.
Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Cardiovascular Agents; Digoxin; Diuretics; Dobutamine; Dopamine; Drug Administration Schedule; Edema; Heart Diseases; Heart Failure; Heart Rate; Hemodynamics; Horse Diseases; Horses; Injections, Intravenous; Lidocaine; Procainamide; Propranolol; Quinidine | 1985 |
Diagnosis and treatment of cardiac arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Agents; Clinical Laboratory Techniques; Diagnosis, Differential; Digoxin; Electrocardiography; Heart Auscultation; Heart Rate; Heart Sounds; Horse Diseases; Horses; Physical Examination; Quinidine | 1985 |
Treatment of fetal cardiac arrhythmias.
Topics: Amiodarone; Arrhythmia, Sinus; Arrhythmias, Cardiac; Chromosome Aberrations; Chromosome Disorders; Diagnosis, Differential; Digoxin; Drug Therapy, Combination; Echocardiography; Edema, Cardiac; Female; Fetal Diseases; Fetal Growth Retardation; Fetal Heart; Gestational Age; Heart Rate; Humans; Karyotyping; Lung; Maternal-Fetal Exchange; Pregnancy; Procainamide; Prognosis; Propranolol; Quinidine; Ultrasonography; Vena Cava, Superior; Verapamil | 1985 |
Tissue digoxin concentrations and digoxin effect during the quinidine-digoxin interaction.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Electrolytes; Kidney; Liver; Muscles; Myocardium; Quinidine; Radioisotopes; Rubidium | 1985 |
Refractory supraventricular tachycardia in the neonate: treatment with temporary antitachycardial pacing.
Topics: Cardiac Pacing, Artificial; Combined Modality Therapy; Digoxin; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Humans; Infant, Newborn; Male; Quinidine; Recurrence; Tachycardia, Paroxysmal; Verapamil | 1985 |
In utero diagnosis and management of fetal tachypnea. A case report.
Topics: Adult; Digoxin; Echocardiography; Electrocardiography; Female; Fetal Diseases; Humans; Infant, Newborn; Pregnancy; Pregnancy in Diabetics; Quinidine; Respiration Disorders; Tachycardia | 1985 |
Interaction between digoxin and commonly coadministered drugs in children.
Topics: Amiodarone; Child, Preschool; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Nifedipine; Quinidine; Spironolactone; Verapamil | 1985 |
Independent and interactive effects of digoxin and quinidine on the atrial fibrillation threshold in dogs.
Topics: Animals; Atrial Fibrillation; Differential Threshold; Digoxin; Dogs; Drug Combinations; Drug Interactions; Electric Stimulation; Quinidine | 1985 |
Effect of spironolactone on the renal clearance of digoxin in dogs.
Topics: Aldosterone; Animals; Digoxin; Dogs; Inulin; Kidney; Metabolic Clearance Rate; Potassium; Quinidine; Sodium; Spironolactone | 1985 |
Digoxin quinidine interaction: a pharmacokinetic study in the isolated perfused rat liver.
Topics: Animals; Bile; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Liver; Metabolic Clearance Rate; Perfusion; Quinidine; Rats; Rats, Inbred Strains | 1985 |
Use of serum drug concentrations in outpatient clinics.
Topics: Carbamazepine; Digoxin; Humans; Medication Systems, Hospital; Outpatient Clinics, Hospital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Quinidine; Theophylline; Wisconsin | 1985 |
Influence of quinidine on the intestinal secretion of digoxin and digitoxin in guinea pigs.
Topics: Animals; Blood Proteins; Colon; Digitoxin; Digoxin; Guinea Pigs; Intestinal Mucosa; Intestines; Jejunum; Kinetics; Male; Quinidine | 1985 |
Ventricular preexcitation in seven dogs and nine cats.
Topics: Animals; Cat Diseases; Cats; Digoxin; Dog Diseases; Dogs; Electrocardiography; Female; Male; Pre-Excitation Syndromes; Propranolol; Quinidine; Tachycardia | 1985 |
[Interaction with digoxin].
Topics: Digoxin; Drug Interactions; Humans; Quinidine; Verapamil | 1985 |
Aneurysmectomy in treatment of ventricular and supraventricular tachyarrhythmias in patients with postinfarction and traumatic ventricular aneurysms.
Topics: Angiocardiography; Atrial Flutter; Cardiac Complexes, Premature; Digoxin; Electrocardiography; Heart Aneurysm; Heart Failure; Heart Injuries; Heart Ventricles; Myocardial Infarction; Propranolol; Quinidine; Tachycardia, Paroxysmal | 1973 |
[The use of digitalis drugs in cardiac patients].
Topics: Atrial Flutter; Calcium; Cardiac Complexes, Premature; Digitalis Glycosides; Digitoxin; Digoxin; Heart Failure; Humans; Lanatosides; Long-Term Care; Ouabain; Quinidine; Tachycardia | 1969 |
Treatment of premature cardiac contractions.
Topics: Bretylium Compounds; Cardiac Complexes, Premature; Digitalis Glycosides; Digoxin; Humans; Lidocaine; Myocardial Infarction; Phenytoin; Potassium Chloride; Procainamide; Propranolol; Quinidine | 1970 |
[Comparison of digoxin toxicity in normal guinea pigs and guinea pigs treated with quinidine].
Topics: Animals; Arrhythmias, Cardiac; Digoxin; Electrocardiography; Guinea Pigs; Male; Quinidine | 1967 |
Proceedings: The antiarrhythmic activity of the prostaglandins A2, E2, and F2alpha.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Body Temperature; Cats; Cold Temperature; Digoxin; Dogs; Guinea Pigs; Heart Rate; Papillary Muscles; Prostaglandins; Quinidine; Strophanthins | 1974 |
Drug effects on cardiac myosin adenosine triphosphatase activity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensin II; Animals; Binding Sites; Calcium; Chloralose; Cyclopropanes; Digoxin; Dogs; Epinephrine; Ethers; Heart; Heart Failure; In Vitro Techniques; Isoproterenol; Lidocaine; Magnesium; Muscle Contraction; Muscle Proteins; Myocardium; Nitrous Oxide; Norepinephrine; Ouabain; Pentobarbital; Pharmacology; Procainamide; Protein Binding; Quinidine; Secobarbital | 1967 |
Repetitive ventricular tachycardia--response to cardioversion, potassium and digitalis.
Topics: Adult; Digoxin; Electric Countershock; Electrocardiography; Ethanolamines; Furosemide; Heart Ventricles; Humans; Male; Potassium Chloride; Procainamide; Quinidine; Tachycardia | 1967 |
Treatment of cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis; Digoxin; Electric Countershock; Heart Block; Heart Ventricles; Humans; Lidocaine; Myocardial Infarction; Pacemaker, Artificial; Phenytoin; Phytotherapy; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Ventricular Fibrillation | 1974 |
The problems of treating disturbances of heart rhythm at home.
Topics: Arrhythmias, Cardiac; Atropine; Cardiac Glycosides; Digoxin; Home Nursing; Humans; Lidocaine; Myocardial Infarction; Ouabain; Practolol; Procainamide; Quinidine; Valsalva Maneuver | 1974 |
Mucoid impaction of a stem bronchus.
Topics: Aged; Arrhythmias, Cardiac; Bronchial Diseases; Bronchography; Digoxin; Female; Hot Temperature; Humans; Humidity; Lung; Mucus; Positive-Pressure Respiration; Postoperative Complications; Pulmonary Atelectasis; Quinidine; Tomography, X-Ray | 1974 |
Case studies of a clinical pharmacist.
Topics: Aged; Alcoholism; Allopurinol; Arrhythmias, Cardiac; Chloral Hydrate; Colchicine; Digoxin; Drug Synergism; Gastrointestinal Hemorrhage; Gout; Hospitals, Teaching; Humans; Liver Diseases; Male; Middle Aged; Nitroglycerin; Patient Care Team; Pharmacists; Pharmacy Service, Hospital; Quinidine; Warfarin; Washington | 1972 |
Wolff-Parkinson-White syndrome. Long-term monitoring for arrhythmias.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Catheterization; Digoxin; Electrocardiography; Female; Heart Rate; Humans; Male; Methods; Middle Aged; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal; Time Factors; Wolff-Parkinson-White Syndrome | 1972 |
Replacement of entire right atrial wall in an infant with a cardiac rhabdomyoma.
Topics: Cardiac Catheterization; Cineangiography; Digoxin; Electrocardiography; Female; Heart Atria; Heart Neoplasms; Humans; Infant; Methods; Quinidine; Rhabdomyoma | 1973 |
Photosensitive livedo reticularis.
Topics: Adrenal Cortex Hormones; Adult; Arm; Digoxin; Female; Furosemide; Humans; Leg; Photosensitivity Disorders; Quinidine; Rheumatic Heart Disease; Vascular Diseases | 1973 |
Drug therapy of heart disease in pediatric patients 3. The therapeutic challenge of supraventricular tachyarrhythmias in infants and children.
Topics: Administration, Oral; Age Factors; Child; Digoxin; Humans; Injections, Intravenous; Lidocaine; Male; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia | 1973 |
Paroxysmal tachycardia in infancy and childhood. II. Paroxysmal ventricular tachycardia and fibrillation.
Topics: Cardiomyopathies; Child; Child, Preschool; Digoxin; Electrocardiography; Female; Follow-Up Studies; Humans; Infant; Male; Myocarditis; Procainamide; Prognosis; Propranolol; Quinidine; Recurrence; Tachycardia, Paroxysmal; Time Factors; Ventricular Fibrillation | 1973 |
Fatal pulmonary hemorrhage complicating use of a flow-directed balloon-tipped catheter in a patient receiving anticoagulant therapy.
Topics: Adult; Anticoagulants; Autopsy; Cardiac Catheterization; Digoxin; Female; Hematoma; Hemorrhage; Humans; Lung Diseases; Pulmonary Artery; Quinidine; Rupture; Warfarin | 1973 |
Anticoagulant therapy with cardiac valve prosthesis during pregnancy.
Topics: Adult; Anticoagulants; Digoxin; Dipyridamole; Female; Heart Valve Prosthesis; Heparin; Humans; Mitral Valve; Pregnancy; Pregnancy Complications, Cardiovascular; Quinidine; Rheumatic Heart Disease; Warfarin | 1973 |
Editorial: Paroxysmal tachycardia in children.
Topics: Child; Child, Preschool; Digoxin; Humans; Infant; Infant, Newborn; Male; Procainamide; Quinidine; Tachycardia, Paroxysmal | 1973 |
Combined use of digitalis and propranolol HCl.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Digoxin; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lanatosides; Propranolol; Quinidine; Refractory Period, Electrophysiological; Tachycardia | 1974 |
Procainamide-induced SLE and lymphoreticular disorders.
Topics: Aortic Diseases; Autopsy; Blindness; Bone Marrow; Digoxin; Drug Therapy, Combination; Heart Diseases; Heparin; Humans; Immunologic Deficiency Syndromes; Kidney; Lupus Erythematosus, Systemic; Lymph Nodes; Lymphoma; Male; Middle Aged; Procainamide; Quinidine; Retinal Artery; Spleen; Thromboembolism; Warfarin | 1974 |
Uncontrolled tachycardia in atrial fibrillation. Management by surgical ligature of A-V bundle and pacemaker.
Topics: Aged; Atrial Fibrillation; Digitoxin; Digoxin; Electrocardiography; Female; Heart Arrest, Induced; Heart Conduction System; Humans; Ligation; Pacemaker, Artificial; Propranolol; Quinidine; Reserpine; Tachycardia | 1974 |
Pacemaker-ventricular blocks.
Topics: Aged; Digoxin; Female; Heart Block; Heart Failure; Heart Rate; Humans; Lidocaine; Male; Myocardial Infarction; Ouabain; Pacemaker, Artificial; Quinidine | 1974 |
Control of heart rate in atrial fibrillation.
Topics: Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Heart Rate; Humans; Propranolol; Quinidine | 1974 |
Symposium on arteriosclerotic heart disease. Tachyarrhythmias. Differential diagnosis and therapy after acute myocardial infarction.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Catecholamines; Diagnosis, Differential; Digoxin; Electric Countershock; Electrocardiography; Heart Conduction System; Humans; Lidocaine; Myocardial Infarction; Potassium; Procainamide; Quinidine; Tachycardia; Time Factors | 1972 |
Chaotic atrial rhythm.
Topics: Aged; Arrhythmias, Cardiac; Digoxin; Electrocardiography; Female; Heart Atria; Humans; Lung Diseases; Male; Middle Aged; Myocardial Infarction; Quinidine; Time Factors | 1972 |
Treatment of ventricular tachycardia in an infant.
Topics: Adolescent; Adult; Age Factors; Angiocardiography; Cardiac Catheterization; Child; Child, Preschool; Digoxin; Drug Synergism; Electric Countershock; Electrocardiography; Female; Heart Ventricles; Humans; Infant; Lidocaine; Male; Procainamide; Quinidine; Tachycardia; Time Factors; Ventricular Fibrillation | 1972 |
Supraventricular tachyarrhythmias. Treatment with edrophonium.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Child; Child, Preschool; Digoxin; Edrophonium; Electrocardiography; Female; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Quinidine; Tachycardia | 1972 |
Paroxysmal supraventricular tachycardia (PST) in infants and children: a clinical review.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Digoxin; Electrocardiography; Female; Heart Defects, Congenital; Heart Ventricles; Humans; Infant; Infant, Newborn; Infections; Male; Methods; Myocarditis; Quinidine; Sulfates; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome | 1972 |
[Complicated cardiac insufficiency and recent therapeutic possibilities: case report].
Topics: Ajmaline; Arrhythmias, Cardiac; Digoxin; Electric Countershock; Female; Glucagon; Heart Failure; Humans; Lanatosides; Middle Aged; Mitral Valve Insufficiency; Phenytoin; Phytotherapy; Plants, Medicinal; Pulmonary Edema; Quinidine; Rauwolfia; Water-Electrolyte Balance | 1971 |
Persistent paroxysmal atrial tachycardia in patient receiving thyroid medication.
Topics: Digoxin; Female; Humans; Metaraminol; Middle Aged; Pacemaker, Artificial; Propranolol; Quinidine; Tachycardia, Paroxysmal; Thyroid Hormones | 1971 |
Acute coronary care: a year's experience at Napier Hospital.
Topics: Anticoagulants; Arrhythmias, Cardiac; Atropine; Digoxin; Electric Countershock; Heart Arrest; Humans; Intensive Care Units; Isoproterenol; Levallorphan; Lidocaine; Medical Staff, Hospital; Meperidine; Myocardial Infarction; New Zealand; Nursing Service, Hospital; Oxygen Inhalation Therapy; Procainamide; Quinidine; Sympathomimetics; Ventricular Fibrillation | 1968 |
[Prolonged supraventricular ectopic tachycardia in the child. (16 cases)].
Topics: Arrhythmia, Sinus; Child; Child, Preschool; Digoxin; Electrocardiography; Electroconvulsive Therapy; Female; Heart Failure; Hemiplegia; Humans; Infant; Male; Methysergide; Neostigmine; Phenylephrine; Procainamide; Propranolol; Quinidine; Reserpine; Tachycardia | 1969 |
Cardioversion in the treatment of atrial flutter.
Topics: Adult; Aged; Atrial Flutter; Digoxin; Electric Countershock; Female; Humans; Male; Middle Aged; Phenobarbital; Propranolol; Quinidine | 1969 |
Suppression of refractory recurrent ventricular tachycardia by transvenous rapid cardiac pacing and antiarrhythmic drugs. Report of seven cases.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atropine; Digitalis Glycosides; Digoxin; Electrocardiography; Female; Heart Ventricles; Humans; Isoproterenol; Lidocaine; Male; Middle Aged; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia; Ventricular Fibrillation | 1970 |
[Disturbances of cardiac rhythm and their treatment].
Topics: Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Digitoxin; Digoxin; Humans; Lidocaine; Metaproterenol; Middle Aged; Phenytoin; Procainamide; Quinidine; Reserpine; Verapamil | 1970 |
Atrial fibrillation. I.
Topics: Aged; Atrial Fibrillation; Digoxin; Epinephrine; Humans; Hyperthyroidism; Isoproterenol; Male; Middle Aged; Propranolol; Quinidine; Ventricular Fibrillation | 1971 |
Cardioversion for drug-resistant supraventricular tachycardia with heart failure.
Topics: Adult; Cholecystectomy; Digoxin; Electric Countershock; Electrocardiography; Female; Heart Failure; Humans; Male; Metaraminol; Middle Aged; Myocardial Infarction; Quinidine; Tachycardia, Paroxysmal | 1968 |
Recurrent ventricular fibrillation precipitated by quinidine. Report of a patient with recovery after 28 paroxysms.
Topics: Adult; Digoxin; Drug Synergism; Electric Countershock; Ethacrynic Acid; Female; Humans; Quinidine; Syncope; Ventricular Fibrillation | 1968 |
[Paroxysmal atrial tachycardia with transition into atrial tachycardia with atrioventricular block during treatment with digitalis].
Topics: Digitalis Glycosides; Digoxin; Heart Block; Humans; Infant; Quinidine; Tachycardia, Paroxysmal | 1968 |
Direct current countershock complications.
Topics: Adolescent; Arrhythmias, Cardiac; Atrial Fibrillation; Digoxin; Electric Countershock; Female; Heart Ventricles; Humans; Male; Middle Aged; Pulmonary Edema; Quinidine; Thromboembolism | 1968 |
Cardioversion of recurrent postoperative supraventricular tachycardia in Wolff-Parkinson-White syndrome.
Topics: Digoxin; Electric Countershock; Humans; Intestinal Obstruction; Male; Middle Aged; Postoperative Complications; Potassium Chloride; Quinidine; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome | 1966 |
Studies with quinidine and digoxin on the cardiac vulnerable period.
Topics: Animals; Arrhythmias, Cardiac; Digoxin; Dogs; Electric Countershock; Electric Stimulation; Electrocardiography; Electrophysiology; Heart Block; Heart Conduction System; Quinidine; Tachycardia; Ventricular Fibrillation | 1966 |
Conversion of atrial fibrillation and flutter by propranolol.
Topics: Adult; Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Digoxin; Electric Countershock; Electrocardiography; Female; Heart Valve Prosthesis; Humans; Male; Middle Aged; Ouabain; Postoperative Complications; Propranolol; Quinidine | 1967 |
The relationship of intracellular depolarization rates and contractility in the dog ventricle in situ: effects of positive and negative inotropic agents.
Topics: Action Potentials; Animals; Cocaine; Digoxin; Dogs; Electrophysiology; Female; Heart; Heart Ventricles; Male; Muscle Contraction; Pentobarbital; Quinidine | 1967 |
Standby pacing for multiple cardiac arrhythmias.
Topics: Adams-Stokes Syndrome; Bradycardia; Digitalis; Digoxin; Electrocardiography; Heart Arrest; Heart Rate; Humans; Myocardial Infarction; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Quinidine; Sympathomimetics | 1967 |
Cardiac arrhythmias following successful surgical closure of atrial septal defect.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Child; Child, Preschool; Digoxin; Electric Countershock; Electrocardiography; Female; Heart Block; Heart Septal Defects, Atrial; Humans; Hypertension, Pulmonary; Hypothermia, Induced; Male; Postoperative Complications; Quinidine | 1967 |
Refractory paroxysmal ventricular tachycardia.
Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Electrocardiography; Heart Ventricles; Humans; Hydrochlorothiazide; Male; Middle Aged; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal | 1967 |
Conversion of atrial fibrillation with quinidine sulfate in a dog.
Topics: Animals; Atrial Fibrillation; Chlorothiazide; Digoxin; Dirofilariasis; Dog Diseases; Dogs; Electrocardiography; Heart Failure; Male; Quinidine | 1967 |
Drugs and the heart. IV. Antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Heart Conduction System; Hemodynamics; Humans; Lidocaine; Mexiletine; Procainamide; Quinidine; Verapamil | 1980 |
Digitalis and quinidine.
Topics: Digitoxin; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Kinetics; Quinidine | 1980 |
Digitalis and quinidine.
Topics: Digoxin; Drug Interactions; Heart Diseases; Humans; Kinetics; Myocardium; Quinidine | 1981 |
[Therapy of cardiac insufficiency with digitalis glycosides].
Topics: Adrenergic beta-Antagonists; Digitalis Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Heart Failure; Humans; Hyperthyroidism; Kidney Failure, Chronic; Liver Diseases; Quinidine | 1981 |
Quinidine and the non-renal elimination of digoxin.
Topics: Animals; Biological Availability; Cyanides; Digoxin; Drug Interactions; In Vitro Techniques; Intestinal Mucosa; Kinetics; Ouabain; Quinidine; Rats | 1982 |
Drug interactions with amiodarone.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Benzofurans; Blood Coagulation Disorders; Calcium; Digoxin; Drug Interactions; Drug Synergism; Heart Arrest; Humans; Kinetics; Quinidine; Tachycardia; Warfarin | 1983 |
PK 10139 and quinidine: interactions with digoxin concentrations in rats and dogs.
Topics: Animals; Anti-Arrhythmia Agents; Digoxin; Dogs; Drug Interactions; Injections, Intravenous; Male; Quinidine; Quinolines; Rats; Rats, Inbred Strains; Species Specificity | 1984 |
[Combinations of some anti-arrhythmia drugs].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Humans; Mexiletine; Propafenone; Propiophenones; Quinidine | 1984 |
Alteration of digoxin pharmacokinetics by a single dose of quinidine.
Topics: Administration, Oral; Aged; Cardiac Complexes, Premature; Coronary Disease; Digoxin; Drug Interactions; Female; Humans; Male; Middle Aged; Quinidine; Time Factors | 1980 |
[Effect of various anti-arrhythmia drugs on serum digoxin level].
Topics: Aged; Anti-Arrhythmia Agents; Biological Availability; Cardiac Complexes, Premature; Digoxin; Disopyramide; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Phenytoin; Procainamide; Quinidine | 1981 |
Use of control steady-state serum digoxin levels for predicting serum digoxin concentration after quinidine administration.
Topics: Aged; Cardiac Complexes, Premature; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Quinidine | 1982 |
Quinidine-digoxin interaction: effect of quinidine on 86Rb-uptake of human erythrocytes.
Topics: Digoxin; Drug Interactions; Erythrocytes; Humans; In Vitro Techniques; Myocardial Contraction; Quinidine; Radioisotopes; Rubidium; Sodium-Potassium-Exchanging ATPase | 1981 |
Interactions between quinidine and cardiac glycosides involving mutual binding sites in the guinea pig.
Topics: Animals; Binding Sites; Binding, Competitive; Digitalis Glycosides; Digitoxin; Digoxin; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardium; Potassium; Quinidine; Sodium; Sodium-Potassium-Exchanging ATPase | 1981 |
Effect of quinidine on the digoxin receptor in vitro.
Topics: Biological Transport, Active; Digoxin; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Protein Binding; Quinidine; Receptors, Drug; Rubidium; Sodium-Potassium-Exchanging ATPase | 1981 |
Changes in red blood cell electrolyte concentrations in digitalis intoxication.
Topics: Adult; Aged; Digoxin; Drug Interactions; Electrocardiography; Erythrocyte Membrane; Erythrocytes; Female; Heart Diseases; Humans; Male; Middle Aged; Potassium; Quinidine; Sodium; Sodium-Potassium-Exchanging ATPase | 1983 |
Influence of quinidine on the binding of [3H]-ouabain and [3H]-digoxin by human lymphocytes.
Topics: Adult; Digoxin; Drug Interactions; Humans; Lymphocytes; Models, Biological; Ouabain; Quinidine; Sodium-Potassium-Exchanging ATPase | 1983 |
Cardiac transplantation--the ideal model for electrophysiologic drug testing?
Topics: Animals; Atropine; Cardiovascular Agents; Digoxin; Disopyramide; Edrophonium; Electrophysiology; Heart; Heart Conduction System; Heart Rate; Heart Transplantation; Humans; Norepinephrine; Quinidine | 1983 |
Bigeminal rhythm on multiple cardiac drug therapy.
Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Digoxin; Drug Therapy, Combination; Electrocardiography; Furosemide; Humans; Hydrochlorothiazide; Male; Methyldopa; Middle Aged; Nitroglycerin; Potassium Chloride; Quinidine | 1984 |
Characteristics of the digoxin-quinidine and digoxin-verapamil interactions in the rat kidney.
Topics: Animals; Binding, Competitive; Digoxin; Drug Interactions; Iodine Radioisotopes; Kidney; Kinetics; Male; Protein Binding; Quinidine; Rats; Rats, Inbred Strains; Verapamil | 1984 |
Fetal supraventricular tachycardia: in utero therapy with digoxin and quinidine.
Topics: Administration, Oral; Adolescent; Adult; Ascites; Digoxin; Drug Therapy, Combination; Echocardiography; Female; Fetal Diseases; Humans; Pregnancy; Quinidine; Tachycardia; Wolff-Parkinson-White Syndrome | 1984 |
Effects of diltiazem on plasma and tissue digoxin levels in mice.
Topics: Animals; Benzazepines; Blood Proteins; Digoxin; Diltiazem; Drug Interactions; Male; Mice; Mice, Inbred Strains; Protein Binding; Quinidine | 1984 |
Quinidine-induced changes in serum and skeletal muscle digoxin concentration; evidence of saturable binding of digoxin to skeletal muscle.
Topics: Aged; Digoxin; Female; Humans; Kinetics; Male; Middle Aged; Muscles; Physical Exertion; Quinidine | 1984 |
[Interaction between digoxin and quinidine].
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1983 |
[Controlled digitalis therapy].
Topics: Cholestyramine Resin; Digitalis Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Heart Failure; Humans; Patient Compliance; Phenobarbital; Quinidine; Rifampin | 1983 |
Digoxin-quinidine interaction. Clinical considerations of two potential mechanisms.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1983 |
Effect of quinidine on differing sensitivities of Purkinje fibers and myocardium to inhibition of monovalent cation transport by digitalis in dogs.
Topics: Animals; Biological Transport, Active; Digoxin; Dogs; Drug Interactions; Female; Heart; Heart Conduction System; Male; Myocardium; Ouabain; Purkinje Fibers; Quinidine; Rubidium | 1983 |
Effect of quinidine on digoxin distribution and elimination in guinea pigs.
Topics: Animals; Bile; Blood Proteins; Digoxin; Drug Interactions; Guinea Pigs; Kinetics; Male; Protein Binding; Quinidine; Time Factors; Tissue Distribution | 1983 |
Interaction of digoxin with verapamil, indomethacin, and other coadministered drugs: a comparative study in rat tissue.
Topics: Animals; Creatinine; Digoxin; Indomethacin; Male; Quinidine; Rats; Rats, Inbred Strains; Verapamil | 1983 |
Prediction of multiple-dose blood level curves of drugs with rapid changes in doses and/or dosing intervals.
Topics: Administration, Oral; Computers; Digoxin; Humans; Infant, Newborn; Infant, Premature; Injections, Intravenous; Pharmaceutical Preparations; Quinidine; Software | 1983 |
Update on the influence of quinidine and other agents on digitalis glycosides.
Topics: Anti-Arrhythmia Agents; Digitalis Glycosides; Digoxin; Drug Interactions; Humans; Quinidine | 1984 |
Reduction of digoxin effect during the digoxin-quinidine interaction.
Topics: Adult; Digoxin; Drug Interactions; Electrocardiography; Electrophysiology; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Quinidine | 1984 |
Digoxin.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1984 |
The influence of rifampin on quinidine and digoxin.
Topics: Aged; Arrhythmias, Cardiac; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Kinetics; Middle Aged; Quinidine; Rifampin; Tuberculosis, Pulmonary | 1984 |
Myocardial monovalent cation transport during the quinidine-digoxin interaction in dogs.
Topics: Animals; Biological Transport, Active; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Kinetics; Male; Myocardium; Quinidine; Rubidium | 1984 |
Pharmacokinetic interaction of single doses of quinine and digoxin in dogs.
Topics: Animals; Digoxin; Dogs; Drug Interactions; Infusions, Parenteral; Kinetics; Quinidine; Quinine | 1984 |
Digoxin-quinidine-spironolactone interaction.
Topics: Adult; Creatinine; Digoxin; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Quinidine; Spironolactone | 1984 |
[Method of evaluating antiarrhythmic therapy in patients with paroxysms of supraventricular tachycardia].
Topics: Adolescent; Adult; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Evaluation; Electric Stimulation; Female; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal; Verapamil | 1984 |
Clinical spectrum and long-term follow-up of isolated mitral valve prolapse in 119 children.
Topics: Adolescent; Adult; Cardiac Catheterization; Child; Child, Preschool; Digoxin; Echocardiography; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Heart Murmurs; Humans; Long-Term Care; Male; Mitral Valve Prolapse; Quinidine; Tachycardia | 1980 |
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs.
Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin | 1980 |
Amiodarone increases plasma digoxin concentrations.
Topics: Amiodarone; Benzofurans; Digoxin; Drug Interactions; Humans; Quinidine | 1981 |
Pharmacologic treatment of cardiac arrhythmias: 25 years of progress.
Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Digoxin; Electrocardiography; Heart; Humans; Lidocaine; Phenytoin; Procainamide; Quinidine | 1983 |
Cardiac effects of treatment with quinidine and digoxin, alone and in combination.
Topics: Adult; Cardiac Output; Digoxin; Echocardiography; Electrocardiography; Heart Rate; Humans; Male; Myocardial Contraction; Quinidine; Stroke Volume; Systole | 1983 |
Effect of quinidine on digoxin bioavailability.
Topics: Aged; Biological Availability; Biotransformation; Chromatography, Thin Layer; Digoxin; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Quinidine | 1983 |
Drugs that increase the serum concentration of digoxin.
Topics: Anti-Bacterial Agents; Calcium Channel Blockers; Digoxin; Drug Interactions; Humans; Quinidine; Quinine; Spironolactone | 1983 |
An electrophysiologic study of the digoxin--quinidine interaction.
Topics: Animals; Digoxin; Dogs; Drug Interactions; Electrocardiography; Electrophysiology; Heart; Membrane Potentials; Purkinje Fibers; Quinidine | 1983 |
Drug toxicity in patients receiving digoxin and quinidine.
Topics: Adult; Aged; Arrhythmias, Cardiac; Digoxin; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Quinidine | 1983 |
Tissue digoxin concentrations during the quinidine-digoxin interaction.
Topics: Animals; Digoxin; Dogs; Drug Interactions; Female; Kidney; Liver; Male; Muscles; Myocardium; Quinidine; Tissue Distribution; Tritium | 1983 |
The quinidine-digoxin interaction in patients with impaired renal function.
Topics: Blood Proteins; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Kidney Diseases; Metabolic Clearance Rate; Protein Binding; Quinidine | 1983 |
Changes in steady state digoxin pharmacokinetics during quinidine therapy in cardiac patients: influence of plasma quinidine concentration.
Topics: Creatinine; Digoxin; Glomerular Filtration Rate; Half-Life; Heart Diseases; Humans; Kinetics; Quinidine | 1983 |
Effect of quinidine on the inotropic effect of cardiac glycosides in isolated cardiac muscle.
Topics: Animals; Cardiac Glycosides; Digitoxin; Digoxin; Drug Interactions; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Quinidine | 1983 |
Renal function and digoxin clearance during quinidine therapy.
Topics: Aged; Atrial Fibrillation; Chronic Disease; Digoxin; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Quinidine | 1982 |
Recognition and management of supraventricular tachyarrhythmias.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Electric Countershock; Electrocardiography; Exercise Test; Heart Ventricles; Humans; Pacemaker, Artificial; Procainamide; Propranolol; Quinidine; Tachycardia | 1981 |
Cardiac drug overdose.
Topics: Arrhythmias, Cardiac; Bretylium Compounds; Cardiovascular Agents; Cardiovascular Diseases; Digoxin; Disopyramide; Humans; Hypotension; Lidocaine; Liver; Phenytoin; Procainamide; Propranolol; Quinidine; Vasodilator Agents | 1982 |
Quinidine-digoxin interaction: evidence for involvement of an extrarenal mechanism.
Topics: Anuria; Blood Proteins; Bundle-Branch Block; Digoxin; Drug Interactions; Female; Humans; Male; Middle Aged; Protein Binding; Quinidine; Renal Dialysis | 1982 |
Digoxin - quinidine interaction.
Topics: Digoxin; Humans; Quinidine | 1982 |
Digoxin--quinidine interaction.
Topics: Animals; Digoxin; Dogs; Drug Interactions; Quinidine | 1982 |
Digitalis toxicity mistaken for jaundice.
Topics: Aged; Color Perception; Digoxin; Drug Interactions; Female; Humans; Quinidine | 1982 |
Investigation of digoxin, quinidine, and disopyramide interactions in rats utilizing parotid saliva, blood, and other tissues.
Topics: Animals; Digoxin; Disopyramide; Drug Interactions; Male; Pyridines; Quinidine; Rats; Rats, Inbred Strains; Saliva; Tissue Distribution | 1982 |
Lack of interaction between digoxin and quinidine in cultured heart cells.
Topics: Animals; Cations; Cells, Cultured; Chick Embryo; Diffusion; Digoxin; Drug Interactions; Heart; Myocardial Contraction; Myocardium; Quinidine; Radioisotopes; Rubidium | 1982 |
The digoxin-quinidine interaction.
Topics: Animals; Arrhythmias, Cardiac; Digoxin; Dogs; Drug Interactions; Gastrointestinal Diseases; Humans; Quinidine; Tissue Distribution | 1982 |
Effect of quinidine on the renal clearance of digoxin in the presence of low and high serum digoxin concentrations.
Topics: Animals; Digoxin; Dogs; Kidney; p-Aminohippuric Acid; Protein Binding; Quinidine | 1982 |
Anti-arrhythmic agents in ischemic heart disease: supraventricular arrhythmias, digitalis toxicity and chronic stable ventricular ectopic beats.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Digitalis; Digoxin; Heart Ventricles; Humans; Plants, Medicinal; Plants, Toxic; Potassium; Quinidine; Verapamil | 1982 |
Mechanism of additive effects of digoxin and quinidine on contractility in isolated cardiac muscle.
Topics: Animals; Atropine; Digoxin; Drug Interactions; Female; Ferrets; Male; Myocardial Contraction; Papillary Muscles; Quinidine | 1982 |
The quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Hemodynamics; Humans; Kinetics; Quinidine | 1982 |
Digoxin-quinidine interaction in patients with chronic renal failure.
Topics: Adult; Digoxin; Drug Interactions; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Quinidine | 1982 |
Digoxin-quinidine interaction in unanesthetized guinea pigs.
Topics: Animals; Digoxin; Drug Interactions; Guinea Pigs; Kinetics; Male; Myocardium; Quinidine; Tissue Distribution | 1982 |
[Digoxin-quinidine interactions: a brief survey of current views].
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1982 |
The quinidine-digoxin interaction.
Topics: Animals; Digoxin; Drug Interactions; Quinidine; Rats | 1982 |
[Drug dosage in the aged].
Topics: Aged; Benzodiazepines; Digoxin; Dose-Response Relationship, Drug; Humans; Pharmaceutical Preparations; Quinidine | 1981 |
Pediatric clinical pharmacology of digoxin.
Topics: Adult; Child; Digoxin; Diuretics; Drug Interactions; Furosemide; Heart; Heart Diseases; Hemoperfusion; Humans; Infant; Infant, Newborn; Male; Myocardium; Oxygen Consumption; Quinidine; Spironolactone | 1981 |
[The quinidine-digoxin interaction (a review of the literature) (author's transl)].
Topics: Digoxin; Drug Synergism; Humans; Metabolic Clearance Rate; Quinidine | 1981 |
Effects of quinidine on serum digoxin concentration: a prospective study.
Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Digoxin; Heart Failure; Heart Ventricles; Humans; Middle Aged; Prospective Studies; Quinidine; Tachycardia, Paroxysmal | 1980 |
Digoxin-quinidine interaction: current status.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1980 |
Digoxin-quinidine interaction.
Topics: Digoxin; Drug Interactions; Humans; Kidney; Quinidine | 1981 |
The digoxin-quinidine interaction: serum protein binding unlikely to be involved.
Topics: Depression, Chemical; Digoxin; Drug Interactions; Humans; Protein Binding; Quinidine | 1981 |
Pharmacokinetics of digoxin in patients subjected to the quinidine-digoxin interaction.
Topics: Adult; Aged; Digoxin; Drug Interactions; Half-Life; Humans; Kinetics; Middle Aged; Quinidine | 1981 |
Digitalis-quinidine interaction.
Topics: Digoxin; Drug Interactions; Humans; Kinetics; Quinidine | 1981 |
[Digoxin-quinidine interactions].
Topics: Arrhythmias, Cardiac; Digoxin; Drug Interactions; Humans; Quinidine | 1981 |
Effect of quinidine on positive inotropic action of digoxin.
Topics: Animals; Cats; Digoxin; Drug Interactions; Myocardial Contraction; Papillary Muscles; Quinidine; Strophanthidin | 1981 |
Effects of quinidine on the cardiac-glycoside sensitivity of guinea-pig and rat heart.
Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport, Active; Digitalis Glycosides; Digoxin; Drug Interactions; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Quinidine; Rats; Sodium | 1981 |
Digoxin-quinidine interaction in patients with renal failure.
Topics: Acetyldigoxins; Adult; Aged; Creatinine; Digoxin; Drug Interactions; Electrocardiography; Female; Heart Diseases; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Quinidine; Renal Dialysis | 1981 |
Effect of quinidine on digoxin concentration in skeletal muscle and serum in patients with atrial fibrillation. Evidence for reduced binding of digoxin in muscle.
Topics: Adult; Atrial Fibrillation; Digoxin; Drug Interactions; Humans; Middle Aged; Muscle, Smooth; Quinidine; Tissue Distribution | 1981 |
[Interaction between digoxin and quinidine].
Topics: Aged; Coronary Disease; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Male; Middle Aged; Quinidine | 1980 |
Cardiovascular drugs for the geriatric patient.
Topics: Aged; Aging; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular Physiological Phenomena; Digoxin; Disopyramide; Humans; Intestinal Absorption; Kidney; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1981 |
Tissue binding sites involved in quinidine-cardiac glycoside interactions.
Topics: Animals; Anti-Arrhythmia Agents; Binding Sites; Binding, Competitive; Cardiac Glycosides; Digoxin; Drug Interactions; Guinea Pigs; Male; Potassium; Quinidine; Rats; Sodium | 1981 |
[Quinidine increases digoxin levels].
Topics: Anti-Arrhythmia Agents; Digoxin; Drug Interactions; Quinidine | 1981 |
Fatal digoxin-quinidine interaction in an elderly woman.
Topics: Aged; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Quinidine | 1981 |
The role of pharmacokinetics in prescribing cardiac drugs.
Topics: Cardiovascular Agents; Digitoxin; Digoxin; Drug Prescriptions; Humans; Kinetics; Quinidine | 1981 |
Clinical aspects of the digoxin-quinidine interaction.
Topics: Aged; Digoxin; Drug Interactions; Female; Humans; Male; Middle Aged; Myocardial Contraction; Quinidine; Retrospective Studies | 1981 |
[Quinidine-digoxin interaction (author's transl)].
Topics: Digoxin; Drug Interactions; Half-Life; Humans; Quinidine; Time Factors | 1981 |
[Digoxin and quinidine: a clinically important drug interaction].
Topics: Binding, Competitive; Digoxin; Drug Synergism; Heart Diseases; Humans; Quinidine; Receptors, Drug | 1981 |
Digoxin bioavailability during quinidine administration.
Topics: Adult; Biological Availability; Digoxin; Drug Interactions; Humans; Middle Aged; Quinidine | 1981 |
Quinidine-digoxin interaction: time course and pharmacokinetics.
Topics: Adult; Aged; Arrhythmias, Cardiac; Creatinine; Digoxin; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Quinidine; Time Factors | 1981 |
[Digoxin-quinidine and digoxin-amiodarone interactions. Effects on blood levels of the cardioactive glycoside].
Topics: Adult; Aged; Amiodarone; Benzofurans; Coronary Disease; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Hypertension; Male; Middle Aged; Quinidine; Rheumatic Heart Disease | 1981 |
Impairment of digoxin clearance by coadministration of quinidine.
Topics: Adult; Biotransformation; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; Heart Diseases; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged; Quinidine; Random Allocation | 1981 |
[Various therapeutic advances].
Topics: Anticoagulants; Cardiovascular Diseases; Cimetidine; Clofibrate; Digoxin; Narcotics; Peptic Ulcer; Prolactin; Quinidine; Vitamin D Deficiency; Yersinia Infections | 1981 |
Digoxin-quinidine interaction in the dog.
Topics: Animals; Appetite Depressants; Digoxin; Dogs; Drug Interactions; Electrocardiography; Quinidine; Vomiting | 1981 |
Quinidine-digoxin interaction.
Topics: Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Quinidine | 1980 |
Quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1980 |
Quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1980 |
Quinidine-digoxin interaction.
Topics: Animals; Binding Sites; Digoxin; In Vitro Techniques; Ouabain; Quinidine | 1980 |
Quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1980 |
Complete abolition of the reentrant supraventricular tachycardia zone using a new modality of cardiac pacing with simultaneous atrioventricular stimulation.
Topics: Adult; Atrioventricular Node; Cardiac Pacing, Artificial; Digoxin; Electrodes; Electrophysiology; Female; Follow-Up Studies; Heart Conduction System; Heart Ventricles; Humans; Male; Middle Aged; Propranolol; Quinidine; Tachycardia; Time Factors; Verapamil | 1980 |
[Interactions of quinidine and digoxin].
Topics: Digoxin; Drug Interactions; Quinidine | 1980 |
Digoxin alters quinidine and quinidine alters digoxin pharmacokinetics in dogs.
Topics: Animals; Digoxin; Dogs; Drug Interactions; Kinetics; Quinidine | 1980 |
The quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Kinetics; Quinidine | 1980 |
The quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Female; Humans; Middle Aged; Quinidine | 1980 |
[Studies on the interaction between digoxin and quinidine by means of monitoring of blood serum drug concentrations].
Topics: Adult; Aged; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Fluorometry; Humans; Male; Middle Aged; Quinidine | 1980 |
Concealed retrograde bypass tracts and enhanced atrioventricular nodal conduction. An unusual subset of patients with refractory paroxysmal supraventricular tachycardia.
Topics: Adolescent; Adult; Atrioventricular Node; Bundle-Branch Block; Digoxin; Electrophysiology; Female; Follow-Up Studies; Heart Conduction System; Humans; Male; Quinidine; Tachycardia, Paroxysmal | 1980 |
Clinical pharmacokinetics: the pharmacological monitoring of plasmatic levels in therapy.
Topics: Digoxin; Drug Administration Schedule; Gentamicins; Humans; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Salicylates; Theophylline | 1980 |
[Risk of simultaneous administration of quinidine and digitalis].
Topics: Aged; Arrhythmias, Cardiac; Digoxin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinidine | 1980 |
Digoxin-quinidine interaction. Changes in canine tissue concentration from steady state with quinidine.
Topics: Animals; Brain; Digitalis Glycosides; Digoxin; Dogs; Gallbladder; Heart; Kidney; Liver; Muscles; Quinidine; Spleen | 1980 |
Effects of selected drugs on serum digoxin concentration in dogs.
Topics: Acetaminophen; Animals; Aspirin; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ibuprofen; Indomethacin; Male; Metabolic Clearance Rate; Quinidine; Quinine; Time Factors | 1980 |
Effect of quinidine on plasma concentration and renal clearance of digoxin. A clinically important drug interaction.
Topics: Creatinine; Digoxin; Drug Interactions; Humans; Quinidine; Time Factors | 1980 |
Effects of antiarrhythmic drugs on atrioventricular conduction in patients with acute myocardial infarction.
Topics: Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Digoxin; Disopyramide; Heart Block; Heart Conduction System; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Procainamide; Propranolol; Quinidine; Time Factors | 1980 |
Reduction of digoxin-induced inotropism during quinidine administration.
Topics: Adult; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Myocardial Contraction; Quinidine | 1980 |
The effect of quinidine on digoxin kinetics in cardiac patients.
Topics: Aged; Creatinine; Digoxin; Drug Interactions; Heart Diseases; Humans; Kidney; Kinetics; Middle Aged; Quinidine | 1980 |
The effect of quinidine and other oral antiarrhythmic drugs on serum digoxin. A prospective study.
Topics: Aged; Anorexia; Anti-Arrhythmia Agents; Digoxin; Disopyramide; Drug Interactions; Female; Humans; Male; Mexiletine; Middle Aged; Nausea; Procainamide; Prospective Studies; Quinidine; Vomiting | 1980 |
Drug interactions and toxicity.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1980 |
[Interaction of digoxin and quinidine].
Topics: Adolescent; Adult; Digoxin; Drug Interactions; Female; Heart Failure; Humans; Male; Middle Aged; Quinidine | 1980 |
[Digoxin and quinidine interaction].
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1980 |
Digoxin-quinidine interaction: in vitro studies in rat tissue.
Topics: Animals; Digoxin; Drug Interactions; Kidney; Muscles; Myocardium; Quinidine; Rats | 1980 |
Serum digoxin concentration and age.
Topics: Adolescent; Adult; Aged; Aging; Blood Urea Nitrogen; Creatinine; Digoxin; Female; Heart Failure; Humans; Liver Function Tests; Male; Middle Aged; Quinidine | 1980 |
The five fingers of cardiology.
Topics: Aged; Anti-Arrhythmia Agents; Cardiac Glycosides; Coronary Disease; Digoxin; Drug Interactions; Humans; Male; Quinidine; Tachycardia | 1980 |
Effect of quinidine on the renal handling of digoxin.
Topics: Aminohippuric Acids; Animals; Digoxin; Dogs; Glomerular Filtration Rate; Quinidine | 1980 |
Further insights into digoxin-quinidine interaction: lack of correlation between serum digoxin concentration and inotropic state of the heart.
Topics: Adult; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Myocardial Contraction; Quinidine; Systole; Time Factors | 1980 |
Quinidine-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Quinidine | 1980 |
Serial electrophysiologic testing of multiple drugs in patients with atrioventricular nodal reentrant paroxysmal tachycardia.
Topics: Administration, Oral; Adult; Aged; Atrioventricular Node; Digoxin; Drug Therapy, Combination; Electrophysiology; Female; Heart Conduction System; Humans; Injections, Intravenous; Male; Middle Aged; Ouabain; Pharmaceutical Preparations; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal | 1980 |
[ECG prodomes of ventricular tachycardia/fibrillation in quinidine-digitalis therapy].
Topics: Adult; Aged; Diastole; Digoxin; Electrocardiography; Female; Humans; Male; Middle Aged; Quinidine; Tachycardia; Ventricular Fibrillation | 1980 |
Digitalis update.
Topics: Arrhythmias, Cardiac; Digitalis Glycosides; Digoxin; Drug Interactions; Heart Failure; Humans; Quinidine | 1981 |
Quinidine therapy and digitalis toxicity.
Topics: Aged; Digoxin; Drug Interactions; Electrocardiography; Humans; Male; Quinidine; Tachycardia | 1981 |
Digoxin pharmacokinetics after quinidine.
Topics: Digoxin; Drug Interactions; Humans; Kinetics; Quinidine | 1981 |
Chaotic atrial tachycardia in childhood.
Topics: Adolescent; Arrhythmias, Cardiac; Child; Child, Preschool; Chronic Disease; Digoxin; Electrocardiography; Female; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Male; Propranolol; Quinidine; Rheumatic Heart Disease; Tachycardia | 1981 |
[A case of arrhythmogenic effects of quinidine, digoxin and finoptin combination].
Topics: Adult; Arrhythmias, Cardiac; Digoxin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinidine; Verapamil | 1995 |
Digoxin-quinidine and digoxin-amiodarone interactions: frequency of occurrence and monitoring in Australian repatriation hospitals.
Topics: Absorption; Amiodarone; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Monitoring, Physiologic; Pharmacy Service, Hospital; Quinidine | 1995 |
Atrial flutter or atrial fibrillation?
Topics: Atrial Fibrillation; Atrial Flutter; Diagnosis, Differential; Digoxin; Drug Therapy, Combination; Electrocardiography; Female; Humans; Middle Aged; Quinidine | 1995 |
An in vitro study of the influence of a drug's molecular weight on its overall (Clt), diffusive (Cld) and convective (Clc) clearance through dialysers.
Topics: Convection; Diffusion; Digoxin; Kinetics; Models, Chemical; Molecular Weight; Pharmaceutical Preparations; Quinidine; Renal Dialysis; Theophylline; Tobramycin; Vancomycin | 1995 |
Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Digoxin; In Vitro Techniques; Inulin; Kidney; Kidney Tubules; Male; Membrane Glycoproteins; Perfusion; Quinidine; Rats; Rats, Wistar; Tritium; Verapamil | 1993 |
Antiarrhythmic drugs in the management of atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Flecainide; Heart; Humans; Propafenone; Quinidine | 1993 |
Electrocardiographic features of atrial tachycardias after operation for congenital heart disease.
Topics: Adolescent; Adult; Atrial Flutter; Child; Child, Preschool; Digoxin; Electrocardiography; Female; Heart Atria; Heart Defects, Congenital; Humans; Infant; Male; Middle Aged; Procainamide; Quinidine; Tachycardia | 1993 |
Quinidine enhances digitalis toxicity at therapeutic serum digoxin levels.
Topics: Aged; Aged, 80 and over; Digitalis; Digoxin; Electrocardiography; Female; Humans; Male; Middle Aged; Plants, Medicinal; Plants, Toxic; Prospective Studies; Quinidine | 1993 |
Rate-based management of fetal supraventricular tachycardia.
Topics: Anti-Arrhythmia Agents; Digoxin; Echocardiography, Doppler, Color; Female; Fetal Diseases; Gestational Age; Heart Rate, Fetal; Humans; Hydrops Fetalis; Pregnancy; Pregnancy Outcome; Quinidine; Retrospective Studies; Tachycardia, Supraventricular; Treatment Outcome; Ultrasonography, Prenatal | 1996 |
Inhibition of the intestinal digoxin absorption and exsorption by quinidine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Drug Interactions; Evaluation Studies as Topic; Intestinal Absorption; Intestine, Small; Male; Metabolic Clearance Rate; Quinidine; Rats; Rats, Sprague-Dawley | 1996 |
Quinidine administration increases steady state serum digoxin concentration in horses.
Topics: Animals; Anti-Arrhythmia Agents; Creatinine; Digoxin; Electroencephalography; Female; Glomerular Filtration Rate; Horses; Kidney; Quinidine; Time Factors | 1995 |
The stereoisomers quinine and quinidine exhibit a marked stereoselectivity in the inhibition of hepatobiliary transport of cardiac glycosides.
Topics: Animals; Biliary Tract; Biological Transport; Calcium Channel Blockers; Cardiac Glycosides; Cardiotonic Agents; Digoxin; Drug Interactions; Liver; Male; Metabolic Clearance Rate; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes.
Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; In Vitro Techniques; Male; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
[Treatment of cardiac arrhythmia in pregnant women].
Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Arrhythmias, Cardiac; Digoxin; Electric Countershock; Female; Heart Valve Diseases; Humans; Lidocaine; Mitral Valve Prolapse; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Secondary Prevention; Smoking; Smoking Prevention; Verapamil | 2000 |
[Unexpected high plasma level of drugs. Blocked transporter can be the cause].
Topics: Anti-Arrhythmia Agents; Biological Availability; Biological Transport, Active; Blood-Brain Barrier; Blood-Testis Barrier; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Digoxin; Drug Interactions; Female; Glycoproteins; Humans; Male; Mixed Function Oxygenases; Pharmaceutical Preparations; Quinidine | 2001 |
The anthelminthic agent albendazole does not interact with p-glycoprotein.
Topics: Albendazole; Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Cell Line; Chromatography, High Pressure Liquid; Digoxin; Enzyme Inhibitors; Humans; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Quinidine; Swine; Tissue Distribution; Verapamil | 2002 |
MDR1-mediated interaction of digoxin with antiarrhythmic or antianginal drugs.
Topics: Amiodarone; Angina Pectoris; Animals; Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Digoxin; Drug Interactions; Humans; LLC-PK1 Cells; Quinidine; Swine | 2002 |
P-glycoprotein-mediated intestinal and biliary digoxin transport in humans.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Transport, Active; Cardiotonic Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Digoxin; Dose-Response Relationship, Drug; Fluorescence Polarization Immunoassay; Humans; Infusions, Intravenous; Intestinal Absorption; Jejunum; Male; Quinidine; Reference Values; Rifampin | 2003 |
[Adverse drug reactions in three older patients, even without changes in medication].
Topics: Adverse Drug Reaction Reporting Systems; Aged; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diclofenac; Digoxin; Diuretics; Drug Interactions; Female; Furosemide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Hypotension, Orthostatic; Kidney; Male; Quinidine; Urinary Bladder Neoplasms | 2003 |
Drug interactions.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Digoxin; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Isoenzymes; Piperazines; Purines; Quinidine; Sildenafil Citrate; Sulfones; Vasodilator Agents; Ventricular Premature Complexes; Verapamil | 2003 |
Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro.
Topics: Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Digoxin; Drug Interactions; Enzyme Inhibitors; Female; Humans; Maternal-Fetal Exchange; Organ Culture Techniques; Placenta; Pregnancy; Quinidine; Verapamil | 2003 |
DIRECT-CURRENT SHOCK IN TREATMENT OF DRUG-RESISTANT CARDIAC ARRHYTHMIAS.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digoxin; Electric Countershock; Electric Stimulation Therapy; Electrocardiography; Humans; Phenindione; Quinidine; Tachycardia | 1964 |
ATRIAL FLUTTER SECONDARY TO DIGITALIS TOXICITY. REPORT OF THREE CASES AND REVIEW OF THE LITERATURE.
Topics: Atrial Flutter; Cardiovascular Diseases; Diagnosis, Differential; Digitalis; Digitoxin; Digoxin; Electrocardiography; Humans; Lanatosides; Potassium; Quinidine; Toxicology | 1964 |
[EFFECTS OF OXYTOCIN ON DIGITALOID ARRHYTHMIAS IN THE DOG].
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Digoxin; Dogs; Electrocardiography; Oxytocin; Pharmacology; Quinidine; Research | 1963 |
DRUGS FOR ARRHYTHMIAS.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Digoxin; Drug Therapy; Electric Countershock; Electric Stimulation Therapy; Potassium; Procaine; Quinidine; Tachycardia; Toxicology | 1964 |
THE USE OF ARTIFICIAL PACEMAKING IN CARDIAC RESUSCITATION.
Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Barbiturates; Digoxin; Electrocardiography; Heart Block; Humans; Myocardial Infarction; Pacemaker, Artificial; Poisoning; Quinidine; Resuscitation; Toxicology | 1964 |
STUDIES ON SOME CARDIAC EFFECT OF TAURINE.
Topics: Acetylcholine; Atropine; Digoxin; Dogs; Epinephrine; Heart; Metabolism; Myocardium; Pharmacology; Potassium; Procainamide; Quinidine; Research; Taurine | 1964 |
CONTROL OF VENTRICULAR TACHYCARDIAS IN DOGS BY B.W. 62-235, A DERIVATIVE OF METHOXAMINE.
Topics: Anti-Arrhythmia Agents; Atropine; Blood Pressure; Blood Pressure Determination; Digoxin; Dogs; Epinephrine; Hydrocarbons; Methoxamine; Ouabain; Pharmacology; Quinidine; Research; Tachycardia; Tachycardia, Ventricular | 1964 |
PAROXYSMAL ATRIAL FIBRILLATION IN WOLFF-PARKINSON-WHITE SYNDROME SIMULATING VENTRICULAR TACHYCARDIA.
Topics: Atrial Fibrillation; Diagnosis, Differential; Digoxin; Electrocardiography; Humans; Procainamide; Prognosis; Quinidine; Tachycardia; Tachycardia, Ventricular; Wolff-Parkinson-White Syndrome | 1964 |
D. C. CARDIOVERSION CAUSING VENTRICULAR FIBRILLATION.
Topics: Aminophylline; Digoxin; Diuretics; Drug Therapy; Electric Countershock; Electrocardiography; Heart Failure; Humans; Hypotension; Metaraminol; Myocardial Infarction; Organomercury Compounds; Phenylephrine; Quinidine; Tachycardia; Ventricular Fibrillation | 1965 |
PARADOXICAL ACCELERATION OF ATRIAL FLUTTER AFTER "CARDIOVERSION".
Topics: Anticoagulants; Atrial Flutter; Digoxin; Drug Therapy; Electric Countershock; Heart Block; Heart Failure; Humans; Quinidine; Tachycardia | 1965 |
A CASE OF WOLFF-PARKINSON-WHITE SYNDROME COMPLICATED BY MYOCARDIAL INFARCTION.
Topics: Digoxin; Drug Therapy; Electrocardiography; Heart Block; Heart Conduction System; Humans; Myocardial Infarction; Quinidine; Reserpine; Tachycardia; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome | 1965 |
The effect of quinidine on tolerance to digoxin.
Topics: Digitalis; Digoxin; Humans; Plant Extracts; Quinidine | 1960 |
Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay.
Topics: Animals; Biological Transport; Digoxin; Liver; Male; Membrane Transport Proteins; Perfusion; Quinidine; Rats; Rats, Sprague-Dawley; Rifampin | 2004 |
Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Culture Techniques; Cells, Cultured; Collagenases; Digoxin; Drug Interactions; Hepatocytes; Male; Progesterone; Quercetin; Quinidine; Rats; Rats, Wistar; Rhodamine 123; Verapamil | 2005 |
The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model.
Topics: Animals; Anti-Inflammatory Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoates; Bridged-Ring Compounds; Digoxin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Models, Animal; Monoterpenes; Morphinans; Paeonia; Quinidine; Rats; Rats, Sprague-Dawley; Sinomenium; Time Factors; Verapamil | 2006 |
Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein.
Topics: Animals; Astemizole; ATP Binding Cassette Transporter, Subfamily B, Member 1; Automation; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Ketoconazole; Quinidine; Reproducibility of Results; Transfection; Tritium | 2006 |
Efavirenz does not interact with the ABCB1 transporter at the blood-brain barrier.
Topics: Alkynes; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzoxazines; Blood-Brain Barrier; Brain; Cell Line; Cyclopropanes; Cyclosporins; Digoxin; Endothelial Cells; Male; Mice; Mice, Knockout; Oxazines; Piperidines; Quinidine; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Triazines | 2006 |
The complexity of intestinal absorption and exsorption of digoxin in rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Ileum; In Vitro Techniques; Intestinal Absorption; Jejunum; Male; Microvilli; Organic Anion Transporters; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Tetrahydroisoquinolines; Verapamil | 2006 |
Effect of therapeutic moderate hypothermia on multi-drug resistance protein 1-mediated transepithelial transport of drugs.
Topics: Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Calcium Channel Blockers; Digoxin; Enzyme Inhibitors; Epithelium; Genes, MDR; Humans; Hypothermia, Induced; Protein Synthesis Inhibitors; Quinidine; Tetracycline | 2006 |
Induction of human P-glycoprotein in Caco-2 cells: development of a highly sensitive assay system for P-glycoprotein-mediated drug transport.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Caco-2 Cells; Cell Differentiation; Cell Growth Processes; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Digoxin; Gene Expression; Humans; Membrane Transport Proteins; Microfilament Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Peptide Transporter 1; Pharmaceutical Preparations; Quinidine; RNA, Messenger; Symporters; Verapamil; Vinblastine | 2006 |
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Digoxin; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Quinidine; Rats; Species Specificity; Verapamil | 2007 |
Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
Topics: Abietanes; Adenosine Triphosphate; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Digoxin; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Microsomes, Liver; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Probenecid; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Temperature; Transfection; Verapamil | 2007 |
Decrease in intracellular concentration causes the shift in Km value of efflux pump substrates.
Topics: Algorithms; Animals; Anti-Arrhythmia Agents; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carrier Proteins; Cell Line; Computer Simulation; Digoxin; Dogs; Humans; Kinetics; Models, Statistical; Permeability; Quinidine | 2007 |
Kinetic identification of membrane transporters that assist P-glycoprotein-mediated transport of digoxin and loperamide through a confluent monolayer of MDCKII-hMDR1 cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamates; Cell Line; Cell Membrane; Digoxin; Dogs; Furans; Kinetics; Loperamide; Quinidine; Sulfonamides | 2008 |
Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Digoxin; Drug Interactions; Humans; Intestinal Mucosa; Quinidine; Rhodamine 123; Ubiquinone; Vitamins | 2008 |
Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Digoxin; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Female; High-Throughput Screening Assays; Humans; Kinetics; Microinjections; Oocytes; Quinidine; Temperature; Verapamil; Vinblastine; Xenopus laevis | 2010 |
If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer?
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cell Membrane; Cell Membrane Permeability; Computer Simulation; Digoxin; Dogs; Drug Interactions; Genes, MDR; Humans; Kidney; Models, Biological; Pharmacokinetics; Protein Binding; Quinidine; Thermodynamics | 2010 |
Is newer better? Propafenone versus quinidine for conversion of atrial fibrillation.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Heart Conduction System; Humans; Injections, Intravenous; Propafenone; Quinidine; Recurrence; Time Factors; Treatment Outcome | 2009 |
Furanocoumarin derivatives in Kampo extract medicines inhibit cytochrome P450 3A4 and P-glycoprotein.
Topics: Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Furocoumarins; Humans; Medicine, Kampo; Midazolam; Quinidine | 2010 |
Comparison of drug permeabilities across the blood-retinal barrier, blood-aqueous humor barrier, and blood-brain barrier.
Topics: Animals; Blood-Aqueous Barrier; Blood-Brain Barrier; Blood-Retinal Barrier; Digoxin; Male; Permeability; Pharmacokinetics; Quinidine; Rats; Rats, Sprague-Dawley; Tritium; Verapamil | 2011 |
Quinidine as an ABCB1 probe for testing drug interactions at the blood-brain barrier: an in vitro in vivo correlation study.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Products; Blood-Brain Barrier; Brain; Cell Line; Chromatography, High Pressure Liquid; Coculture Techniques; Cyclosporins; Digoxin; Dogs; Drug Combinations; Drug Evaluation, Preclinical; Drug Interactions; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; High-Throughput Screening Assays; Immunosuppressive Agents; Male; Microdialysis; Quinidine; Rats; Rats, Wistar | 2011 |
Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na⁺/K⁺ ATPase digoxin binding.
Topics: Animals; Anti-Arrhythmia Agents; Area Under Curve; Bile; Cell Membrane; Digoxin; Drug Interactions; Liver; Male; Quinidine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2012 |
The liver partition coefficient-corrected inhibitory quotient and the pharmacokinetic-pharmacodynamic relationship of directly acting anti-hepatitis C virus agents in humans.
Topics: Animals; Antiviral Agents; Cells, Cultured; Digoxin; Doxorubicin; Hepacivirus; Hepatocytes; Humans; Imipramine; Liver; Male; Mice; Quinidine; Rats; Rats, Sprague-Dawley; Verapamil | 2012 |
A simplified protocol employing elacridar in rodents: a screening model in drug discovery to assess P-gp mediated efflux at the blood brain barrier.
Topics: Acridines; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Chromatography, Liquid; Cost-Benefit Analysis; Digoxin; Drug Design; Drug Interactions; Half-Life; Injections, Intravenous; Male; Mice; Propanolamines; Quinidine; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tetrahydroisoquinolines; Time Factors; Tissue Distribution | 2012 |
Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Cyclosporine; Digoxin; Dogs; Furans; Gene Expression; Humans; Ketoconazole; Kinetics; Loperamide; Madin Darby Canine Kidney Cells; Protein Binding; Quinidine; Sulfonamides; Tetrahydroisoquinolines; Vinblastine | 2013 |
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil | 2014 |
Establishment of optimized MDCK cell lines for reliable efflux transport studies.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Digoxin; Dogs; Flow Cytometry; Fluoresceins; Gene Expression; Humans; Madin Darby Canine Kidney Cells; Quinidine; Transfection; Vinblastine | 2014 |
Characterization of gastrointestinal absorption of digoxin involving influx and efflux transporter in rats: application of mdr1a knockout (-/-) rats into absorption study of multiple transporter substrate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Digoxin; Flavanones; Gastrointestinal Absorption; Gene Knockout Techniques; Organic Anion Transporters, Sodium-Independent; Quinidine; Rats; Rats, Sprague-Dawley | 2014 |
Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats.
Topics: Animals; Aqueous Humor; ATP Binding Cassette Transporter, Subfamily B; Biological Transport, Active; Blood-Aqueous Barrier; Blood-Brain Barrier; Blood-Retinal Barrier; Brain; Calcium Channel Blockers; Capillary Permeability; Digoxin; Gene Knockout Techniques; Male; Quinidine; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Retina; Verapamil; Voltage-Gated Sodium Channel Blockers | 2014 |
Quantitative Targeted Absolute Proteomics of Transporters and Pharmacoproteomics-Based Reconstruction of P-Glycoprotein Function in Mouse Small Intestine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Dexamethasone; Digoxin; Duodenum; Ileum; Intestinal Absorption; Intestine, Small; Jejunum; Loperamide; Mice; Mice, Knockout; Proteomics; Quinidine; Verapamil; Vinblastine | 2016 |
Extrapolation of Elementary Rate Constants of P-glycoprotein-Mediated Transport from MDCKII-hMDR1-NKI to Caco-2 Cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Carbamates; Cell Culture Techniques; Cell Membrane; Cell Membrane Permeability; Digoxin; Dogs; Furans; Humans; Kinetics; Loperamide; Madin Darby Canine Kidney Cells; Models, Biological; Quinidine; Sulfonamides | 2017 |
Pharmacokinetic interaction of green tea beverage containing cyclodextrins and high concentration catechins with P-glycoprotein substrates in LLC-GA5-COL150 cells in vitro and in the small intestine of rats in vivo.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Catechin; Cell Line; Cyclodextrins; Digoxin; Food-Drug Interactions; Intestinal Absorption; Intestine, Small; Male; Quinidine; Rats; Rats, Sprague-Dawley; Rhodamine 123; Solubility; Swine; Tea | 2017 |
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
Topics: Blood-Brain Barrier; Capillary Permeability; Cell Culture Techniques; Cell Line; Central Nervous System Agents; Claudin-5; Digoxin; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Isoquinolines; Models, Neurological; Occludin; Propranolol; Quinidine; Zonula Occludens-1 Protein | 2018 |
Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein Induction.
Topics: Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dabigatran; Digoxin; Drug Interactions; Female; Gene Expression Regulation; Healthy Volunteers; Humans; Intestinal Mucosa; Male; Models, Biological; Propanolamines; Quinidine; Rifampin | 2019 |
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine | 2021 |
Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Computer Simulation; Dabigatran; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestines; Itraconazole; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Quinidine; Verapamil; Young Adult | 2022 |
Robust physiologically based pharmacokinetic model of rifampicin for predicting drug-drug interactions via P-glycoprotein induction and inhibition in the intestine, liver, and kidney.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Digoxin; Drug Interactions; Humans; Intestines; Kidney; Liver; Membrane Transport Proteins; Models, Biological; Quinidine; Rifampin | 2022 |