Page last updated: 2024-08-17

quinidine and diazepam

quinidine has been researched along with diazepam in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (29.09)	18.7374
1990's	2 (3.64)	18.2507
2000's	19 (34.55)	29.6817
2010's	17 (30.91)	24.3611
2020's	1 (1.82)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Adachi, Y; Sugiyama, Y; Suzuki, H	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Fetzer, L; Frotscher, M; Hartmann, RW; Kruchten, P; Marchais-Oberwinkler, S; Messinger, J; Müller-Vieira, U; Neugebauer, A; Scherer, C; Thole, H; Ziegler, E	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Frotscher, M; Hartmann, RW; Henn, C; Kruchten, P; Marchais-Oberwinkler, S; Werth, R; Wetzel, M; Ziegler, E	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Cho, H; Elkamhawy, A; Heo, JC; Kim, HY; Kim, KH; Lee, CO; Nam, DH; Pae, AN; Park, WK; Roh, EJ; Seol, HJ; Viswanath, AN; Yang, H	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Handzlik, J; Jastrzębska-Więsek, M; Kieć-Kononowicz, K; Kucwaj-Brysz, K; Latacz, G; Lubelska, A; Partyka, A; Wesołowska, A	1
Fishel, B; Herzberg, M; Wiener, MH	1
Bosoni, C; May, L; Prevosti, L; Soldati, B	1
Aster, RH; Cimo, PL; Desai, RG; Pino, JL; Pisciotta, AV	1
Duff, HJ; Rahmberg, M; Sheldon, RS	1
Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y	1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y	1
Lavender, MK; Parkes, MW	1
Riegelman, S	1
Giorgetti, L; Perez, MV; Servi, S	1
McIntosh, HD; Wagner, GS	1
Aberg, H; Cullhed, I	1
Marriott, HJ	1
Chaffee, WG; Naney, AP	1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL	1
Massumi, RA; Nutter, DO	1
Müller, FO; Steyn, JM	1
Rambhau, D; Rao, BR	1
Ma, Y; Tang, X; Yang, X	1
Andersen, R; Borchardt, RT; Chen, W; Nielsen, LH; Yang, JZ	1
Shou, M	1
Mealey, KL; Nelson, FR; Raunig, DL; Schmidt, KR; Waiting, D	1
Ito, S; Iwamoto, K; Kamimura, H; Mizunaga, M; Nakayama, K; Negoro, T; Nishiwaki, M; Nomura, Y; Suemizu, H; Yamazaki, H; Yoneda, N	1

Reviews

6 review(s) available for quinidine and diazepam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Cardioversion in atrial fibrillation. Clinical study of 177 cases]. Minerva cardioangiologica, 1978, Volume: 26, Issue:5 Topics: Adult; Aged; Atrial Fibrillation; Diazepam; Digitalis Glycosides; Electric Countershock; Female; Humans; Male; Middle Aged; Quinidine	1978
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats. Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:5 Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin	1985
The use of drugs in achieving successful DC cardioversion. Progress in cardiovascular diseases, 1969, Volume: 11, Issue:5 Topics: Anesthesia; Anticoagulants; Arrhythmias, Cardiac; Barbiturates; Diazepam; Digitalis Glycosides; Electric Countershock; Heart Conduction System; Humans; Quinidine; Tachycardia	1969
[Arrhythmias. 5. Electroconversion--risks, indications, drug therapy]. Lakartidningen, 1971, Jun-14, Volume: 68 Topics: Anesthesia, General; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmias, Cardiac; Diazepam; Digitalis Glycosides; Electric Countershock; Heart Block; Humans; Middle Aged; Quinidine; Thromboembolism	1971
Management of cardiac dysrhythmias complicating acute myocardial infarction. Geriatrics, 1968, Volume: 23, Issue:9 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Bretylium Compounds; Diazepam; Edetic Acid; Electrocardiography; Heart Block; Humans; Hydrocortisone; Isoproterenol; Lidocaine; Metaraminol; Myocardial Infarction; Neostigmine; Norepinephrine; Ouabain; Phenytoin; Potassium Chloride; Procainamide; Propranolol; Quinidine; Tachycardia; Valsalva Maneuver	1968

Trials

2 trial(s) available for quinidine and diazepam

Article	Year
Absence of a pharmacokinetic interaction between quinidine and diazepam. Drug metabolism and drug interactions, 1995, Volume: 12, Issue:1 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Biological Availability; Cross-Over Studies; Diazepam; Drug Interactions; Half-Life; Humans; Hypnotics and Sedatives; Male; Quinidine; Spectrometry, Fluorescence	1995
Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs. Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:5 Topics: Animals; Anti-Anxiety Agents; Antidiarrheals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cross-Over Studies; Cyclosporine; Diazepam; Dogs; Enzyme Inhibitors; Female; Genotype; HIV Protease Inhibitors; Loperamide; Male; Nelfinavir; Quinidine; Substrate Specificity	2010

Article

Year

Absence of a pharmacokinetic interaction between quinidine and diazepam.

Drug metabolism and drug interactions, 1995, Volume: 12, Issue:1

Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Biological Availability; Cross-Over Studies; Diazepam; Drug Interactions; Half-Life; Humans; Hypnotics and Sedatives; Male; Quinidine; Spectrometry, Fluorescence

1995

Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs.

Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:5

Topics: Animals; Anti-Anxiety Agents; Antidiarrheals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cross-Over Studies; Cyclosporine; Diazepam; Dogs; Enzyme Inhibitors; Female; Genotype; HIV Protease Inhibitors; Loperamide; Male; Nelfinavir; Quinidine; Substrate Specificity

2010

Other Studies

47 other study(ies) available for quinidine and diazepam

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein. Pharmaceutical research, 2001, Volume: 18, Issue:12 Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent disease Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Caco-2 Cells; Computer Simulation; Drug Design; Enzyme Inhibitors; Estrogens; Humans; Hydrogen Bonding; Liver; Male; Microsomes, Liver; Models, Molecular; Molecular Structure; Naphthalenes; Neoplasms, Hormone-Dependent; Quinolines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
New drug-like hydroxyphenylnaphthol steroidomimetics as potent and selective 17β-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of estrogen-dependent diseases. Journal of medicinal chemistry, 2011, Jan-27, Volume: 54, Issue:2 Topics: 17-Hydroxysteroid Dehydrogenases; Administration, Oral; Animals; Biological Availability; Cell Line, Tumor; Cell Membrane Permeability; Cell-Free System; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Liver; Male; Microsomes; Molecular Mimicry; Naphthols; Phenols; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recombinant Proteins; Steroids; Structure-Activity Relationship	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM). European journal of medicinal chemistry, 2015, Oct-20, Volume: 103 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Models, Molecular; Molecular Conformation; Quinazolines; Structure-Activity Relationship; Temozolomide; Urea	2015
MF-8, a novel promising arylpiperazine-hydantoin based 5-HT Bioorganic & medicinal chemistry letters, 2018, 03-01, Volume: 28, Issue:5 Topics: Dose-Response Relationship, Drug; Humans; Hydantoins; Molecular Structure; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship	2018
Hepatic microsomal enzyme induction and its evaluation in a clinical laboratory. Israel journal of medical sciences, 1977, Volume: 13, Issue:5 Topics: Adult; Aged; Diazepam; Digoxin; Enzyme Induction; Female; Furosemide; gamma-Glutamyltransferase; Glucaric Acid; Humans; Male; Methyldopa; Microsomes, Liver; Middle Aged; Quinidine	1977
Detection of drug-dependent antibodies by the 51Cr platelet lysis test: documentation of immune thrombocytopenia induced by diphenylhydantoin, diazepam, and sulfisoxazole. American journal of hematology, 1977, Volume: 2, Issue:1 Topics: Adolescent; Antibodies; Antibody Specificity; Blood Platelets; Chromium Radioisotopes; Diazepam; Female; Humans; Male; Middle Aged; Phenytoin; Quinidine; Quinine; Sulfisoxazole; Thrombocytopenia	1977
Role of quinidine in the mexiletine-quinidine interaction: electrophysiologic correlates of enhanced antiarrhythmic efficacy. Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Diazepam; Dogs; Drug Combinations; Drug Interactions; Heart Conduction System; Mexiletine; Quinidine; Quinine; Refractory Period, Electrophysiological	1990
Effect of quinidine on the hepatic uptake of digoxin in guinea pigs. Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:1 Topics: Animals; Diazepam; Digoxin; Guinea Pigs; In Vitro Techniques; Indicator Dilution Techniques; Liver; Ouabain; Quinidine; Temperature	1989
The activity of beta-adrenoceptor blocking agents in protecting mice from the cardiotoxic effects of ouabain. The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:4 Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Animals; Anti-Arrhythmia Agents; Diazepam; Dose-Response Relationship, Drug; Electrocardiography; Ethanolamines; Lidocaine; Male; Mice; Mice, Inbred Strains; Nitrobenzenes; Ouabain; Phenethylamines; Propranolol; Propylamines; Quinidine; Sotalol	1973
Physiological and pharmacokinetic complexities in bioavailability testing. Pharmacology, 1972, Volume: 8, Issue:1 Topics: Administration, Oral; Animals; Autoradiography; Biopharmaceutics; Carbon Isotopes; Cats; Diazepam; Dosage Forms; Half-Life; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestines; Kinetics; Male; Mice; Nortriptyline; Propranolol; Quinidine; Radiography; Solubility; Stomach; Tetracycline; Time Factors; Water	1972
[Case of acute quinidine sulfate poisoning]. Minerva pediatrica, 1973, Mar-17, Volume: 25, Issue:9 Topics: Acute Disease; Diazepam; Electrocardiography; Heart; Humans; Infant; Lactates; Male; Poisoning; Quinidine	1973
Diazepam for cardioversion. JAMA, 1971, Jan-18, Volume: 215, Issue:3 Topics: Arrhythmias, Cardiac; Diazepam; Digitalis Glycosides; Humans; Quinidine; Tachycardia	1971
Observations on models used for the evaluation of antiarrhythmic drugs. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1 Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine	1971
Diazepam in cardioversion. The New England journal of medicine, 1965, Sep-16, Volume: 273, Issue:12 Topics: Diazepam; Electric Countershock; Humans; Meperidine; Quinidine	1965
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jan-26, Volume: 57, Issue:4 Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin	1980
[The adsorption on attapulgite and cross-linked agar beads entrapped attapulgite(CAA)]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2000, Volume: 17, Issue:4 Topics: Adsorption; Agar; Chlorpromazine; Diazepam; Magnesium Compounds; Phenobarbital; Quinidine; Silicon Compounds	2000
Evaluation of the permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs across the blood-brain barrier using an in situ perfused rat brain model. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:2 Topics: Acridines; Algorithms; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Blood-Brain Barrier; Brain Chemistry; Chromatography, High Pressure Liquid; Diazepam; Enkephalin, Leucine-2-Alanine; GABA Modulators; In Vitro Techniques; Isoquinolines; Kinetics; Male; Mass Spectrometry; Perfusion; Prodrugs; Quinidine; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines	2002
Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450. Methods in enzymology, 2002, Volume: 357 Topics: Benzoflavones; Binding Sites; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Diclofenac; Enzyme Activation; Enzyme Inhibitors; Kinetics; Losartan; Models, Biological; Protein Binding; Quinidine; Recombinant Proteins	2002
Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data. Drug metabolism and pharmacokinetics, 2020, Volume: 35, Issue:4 Topics: Acetamides; Albuterol; Animals; Carbamates; Chromatography, Liquid; Diazepam; Diclofenac; Digitoxin; Humans; Itraconazole; Ketoprofen; Liver; Metabolic Clearance Rate; Mice; Mice, Transgenic; Naproxen; Pharmaceutical Preparations; Phenytoin; Piperidines; Pravastatin; Pyrimidines; Quinidine; Tandem Mass Spectrometry; Telmisartan; Terfenadine; Verapamil	2020