Page last updated: 2024-08-17

quinidine and dextromethorphan - quinidine combination

quinidine has been researched along with dextromethorphan - quinidine combination in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (13.33)29.6817
2010's26 (86.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Appel, SH; Berg, JE; Bradley, WG; Brooks, BR; Olney, RK; Pope, LE; Smith, RA; Thisted, RA1
Hauser, SL; Johnston, SC1
Rosen, H1
Drmić, S; Mimica, N; Presecki, P1
Olney, N; Rosen, H1
Garnock-Jones, KP1
Pioro, EP1
Hepner, A; Pope, LE; Shaibani, AI; Thisted, R1
Stahl, SM2
Casselman, J; Patatanian, E1
Appel, SH; Formella, AE; Lomen-Hoerth, C; Pattee, GL; Pope, LE; Wymer, JP1
Ferrara, JM1
Deeks, ED; Yang, LP1
Antonsdottir, IM; Keltz, M; Porsteinsson, AP; Smith, J1
Cutler, AJ; D'Amico, S; Davis, CS; Doody, RS; Ledon, F; Shin, P; Siffert, J; Yonan, C1
Carroll, BT; Denysenko, L; Mitchell, JL; Turner, J1
Garcia-Baran, D; Geers, M; Johnson, TM; Shen, J; Wagner, J1
Alexander, DN; Cutler, AJ; D'Amico, S; Davis, CS; Doody, RS; Formella, AE; Hammond, FM; Ledon, F; Sauve, W; Shin, P; Siffert, J; Yonan, C; Zorowitz, RD1
Crumpacker, DW1
Garay, RP; Grossberg, GT1
Reiman, AT; Schrader, JV; Wahler, RG1
Sauvé, WM1
Cudkowicz, M; Goslin, K; Macklin, EA; Meekins, G; Myers, K; Pattee, G; Pioro, E; Schoenfeld, D; Sirdofsky, M; Smith, R; Wymer, J; Yu, H1
Charpeaud, T; Citrome, L; Correll, CU; Garay, RP; Hameg, A; Llorca, PM; Zarate, CA1
Bell, JS; Chaiyakunapruk, N; Hilmer, SN; Kongpakwattana, K; Sawangjit, R; Tawankanjanachot, I1
Calcagno, HE; Chen, Q; Shad, M1
Allison, KM; Berry, JD; Cordella, C; Green, JR; Macklin, EA; Pattee, GL; Pioro, EP; Richburg, BD; Smith, RA1
Fralick, M; Kesselheim, AS; Sacks, CA1

Reviews

12 review(s) available for quinidine and dextromethorphan - quinidine combination

ArticleYear
Dextromethorphan/quinidine sulfate for pseudobulbar affect.
    Drugs of today (Barcelona, Spain : 1998), 2008, Volume: 44, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Dextromethorphan; Drug Combinations; Humans; Pseudobulbar Palsy; Quinidine; Selective Serotonin Reuptake Inhibitors

2008
AVP-923, a combination of dextromethorphan hydrobromide and quinidine sulfate for the treatment of pseudobulbar affect and neuropathic pain.
    IDrugs : the investigational drugs journal, 2010, Volume: 13, Issue:4

    Topics: Animals; Clinical Trials as Topic; Dextromethorphan; Diabetic Neuropathies; Drug Combinations; Humans; Mood Disorders; Quinidine

2010
Dextromethorphan/quinidine: in pseudobulbar affect.
    CNS drugs, 2011, Volume: 25, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Crying; Dextromethorphan; Drug Combinations; Emotions; Female; Humans; Laughter; Male; Mood Disorders; Multiple Sclerosis; Quinidine

2011
Current concepts in the pharmacotherapy of pseudobulbar affect.
    Drugs, 2011, Jun-18, Volume: 71, Issue:9

    Topics: Antidepressive Agents; Crying; Dextromethorphan; Drug Combinations; Humans; Laughter; Mood Disorders; Off-Label Use; Quinidine

2011
Dextromethorphan/quinidine for the treatment of pseudobulbar affect.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2014, Volume: 29, Issue:4

    Topics: Clinical Trials as Topic; Crying; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Humans; Laughter; Pseudobulbar Palsy; Quinidine; Receptors, sigma; Sigma-1 Receptor; Treatment Outcome

2014
Dextromethorphan/quinidine: a review of its use in adults with pseudobulbar affect.
    Drugs, 2015, Volume: 75, Issue:1

    Topics: Adult; Dextromethorphan; Drug Combinations; Humans; Mood Disorders; Nervous System Diseases; Quinidine

2015
Advancements in the treatment of agitation in Alzheimer's disease.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:11

    Topics: Alzheimer Disease; Cannabinoid Receptor Agonists; Cannabinoids; Citalopram; Clinical Trials, Phase III as Topic; Dextromethorphan; Drug Combinations; Humans; Psychomotor Agitation; Quinidine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2015
Enhancing Approaches to the Identification and Management of Pseudobulbar Affect.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:9

    Topics: Affective Symptoms; Crying; Dextromethorphan; Drug Combinations; Female; Humans; Laughter; Middle Aged; Multiple Sclerosis; Neurotransmitter Agents; Quinidine

2016
AVP-786 for the treatment of agitation in dementia of the Alzheimer's type.
    Expert opinion on investigational drugs, 2017, Volume: 26, Issue:1

    Topics: Alzheimer Disease; Animals; Brain; Deuterium; Dextromethorphan; Drug Combinations; Humans; Psychomotor Agitation; Quinidine; Randomized Controlled Trials as Topic; Tissue Distribution; Treatment Outcome

2017
Recognizing and treating pseudobulbar affect.
    CNS spectrums, 2016, Volume: 21, Issue:S1

    Topics: Dextromethorphan; Drug Combinations; Early Diagnosis; Excitatory Amino Acid Antagonists; Humans; Pseudobulbar Palsy; Quinidine

2016
Investigational drugs in recent clinical trials for treatment-resistant depression.
    Expert review of neurotherapeutics, 2017, Volume: 17, Issue:6

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Depressive Disorder, Treatment-Resistant; Dextromethorphan; Drug Combinations; Drugs, Investigational; Humans; Quinidine

2017
Pharmacological treatments for alleviating agitation in dementia: a systematic review and network meta-analysis.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:7

    Topics: Antipsychotic Agents; Dementia; Dextromethorphan; Drug Combinations; Humans; Network Meta-Analysis; Psychometrics; Psychomotor Agitation; Quinidine; Randomized Controlled Trials as Topic; Risperidone; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome

2018

Trials

5 trial(s) available for quinidine and dextromethorphan - quinidine combination

ArticleYear
Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Double-Blind Method; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pseudobulbar Palsy; Quinidine; Receptors, N-Methyl-D-Aspartate; Treatment Outcome

2004
Efficacy and safety of dextromethorphan/quinidine at two dosage levels for diabetic neuropathic pain: a double-blind, placebo-controlled, multicenter study.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Dextromethorphan; Diabetic Neuropathies; Double-Blind Method; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Placebos; Quinidine

2012
An open-label multicenter study to assess the safety of dextromethorphan/quinidine in patients with pseudobulbar affect associated with a range of underlying neurological conditions.
    Current medical research and opinion, 2014, Volume: 30, Issue:11

    Topics: Adolescent; Adult; Affective Symptoms; Aged; Aged, 80 and over; Cohort Studies; Crying; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Laughter; Male; Middle Aged; Pseudobulbar Palsy; Quinidine; Treatment Outcome; Young Adult

2014
PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury.
    BMC neurology, 2016, Jun-09, Volume: 16

    Topics: Aged; Brain Injuries, Traumatic; Dementia; Dextromethorphan; Drug Administration Schedule; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Pseudobulbar Palsy; Quinidine; Severity of Illness Index; Stroke; Treatment Outcome

2016
Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2017, Volume: 14, Issue:3

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cross-Over Studies; Dextromethorphan; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Quinidine

2017

Other Studies

13 other study(ies) available for quinidine and dextromethorphan - quinidine combination

ArticleYear
Marketing and drug costs: who is laughing and crying?
    Annals of neurology, 2007, Volume: 61, Issue:2

    Topics: Affective Symptoms; Dextromethorphan; Drug Combinations; Drug Costs; Drug Industry; Humans; Laughter; Marketing; Quinidine; Smiling

2007
Involuntary emotional expression disorder in Alzheimer's disease - psychopharmacotherapy aspects.
    Psychiatria Danubina, 2009, Volume: 21, Issue:3

    Topics: Affective Symptoms; Alzheimer Disease; Clinical Trials as Topic; Combined Modality Therapy; Croatia; Crying; Dextromethorphan; Drug Approval; Drug Combinations; Expressed Emotion; Humans; Laughter; Psychotropic Drugs; Quinidine; United States

2009
Dextromethorphan/quinidine (Nuedexta) for pseudobulbar affect.
    The Medical letter on drugs and therapeutics, 2011, Jun-13, Volume: 53, Issue:1366

    Topics: Dextromethorphan; Drug Combinations; Drug Interactions; Humans; Pseudobulbar Palsy; Quinidine

2011
Mechanism of action of dextromethorphan/quinidine:comparison with ketamine.
    CNS spectrums, 2013, Volume: 18, Issue:5

    Topics: Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Humans; Ketamine; Mood Disorders; Quinidine

2013
CRPS-related neurogenic edema responsive to dextromethorphan/quinidine.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:11

    Topics: Adult; Causalgia; Dextromethorphan; Drug Combinations; Edema; Female; Humans; Leg; Quinidine

2014
An open-label study to assess safety, tolerability, and effectiveness of dextromethorphan/quinidine for pseudobulbar affect in dementia: PRISM II results.
    CNS spectrums, 2016, Volume: 21, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dementia; Dementia, Vascular; Dextromethorphan; Diarrhea; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Frontotemporal Dementia; Headache; Humans; Lewy Body Disease; Male; Middle Aged; Pseudobulbar Palsy; Quinidine; Urinary Tract Infections

2016
Dextromethorphan/quinidine withdrawal-emergent catatonia.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2016, Volume: 28, Issue:2

    Topics: Aged; Catatonia; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Humans; Male; Psychotic Disorders; Quinidine; Receptors, N-Methyl-D-Aspartate

2016
Therapeutic Approach of a High Functioning Individual With Traumatic Brain Injury and Subsequent Emotional Volatility With Features of Pathological Laughter and Crying With Dextromethorphan/Quinidine.
    Medicine, 2016, Volume: 95, Issue:12

    Topics: Adult; Affective Symptoms; Brain Concussion; Brain Injuries; Crying; Dextromethorphan; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Humans; Laughter; Male; Quinidine; Stress Disorders, Post-Traumatic

2016
Dextromethorphan-quinidine-responsive pseudobulbar affect (PBA): psychopharmacological model for wide-ranging disorders of emotional expression?
    CNS spectrums, 2016, Volume: 21, Issue:6

    Topics: Dextromethorphan; Drug Combinations; Emotions; Excitatory Amino Acid Antagonists; Humans; Models, Theoretical; Pseudobulbar Palsy; Psychopharmacology; Quinidine; Receptors, Glutamate; Receptors, Serotonin; Receptors, sigma

2016
Use of Compounded Dextromethorphan-Quinidine Suspension for Pseudobulbar Affect in Hospice Patients.
    Journal of palliative medicine, 2017, Volume: 20, Issue:3

    Topics: Aged, 80 and over; Crying; Dextromethorphan; Drug Combinations; Female; Hospice Care; Humans; Laughter; Male; Medical Audit; Pseudobulbar Palsy; Quinidine; Retrospective Studies; Treatment Outcome

2017
Efficacy of Dextromethorphan/Quinidine for Patients With Psychosis-Related Aggression: A Retrospective Case Series.
    The primary care companion for CNS disorders, 2018, Jun-28, Volume: 20, Issue:3

    Topics: Aged; Aggression; Dextromethorphan; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Impulsive Behavior; Male; Middle Aged; Outcome Assessment, Health Care; Psychotic Disorders; Quinidine; Retrospective Studies

2018
Additional evidence for a therapeutic effect of dextromethorphan/quinidine on bulbar motor function in patients with amyotrophic lateral sclerosis: A quantitative speech analysis.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:12

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Dextromethorphan; Drug Combinations; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Quinidine; Speech

2018
Assessment of Use of Combined Dextromethorphan and Quinidine in Patients With Dementia or Parkinson Disease After US Food and Drug Administration Approval for Pseudobulbar Affect.
    JAMA internal medicine, 2019, 02-01, Volume: 179, Issue:2

    Topics: Aged; Amyotrophic Lateral Sclerosis; Dementia; Dextromethorphan; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Parkinson Disease; Pseudobulbar Palsy; Quinidine; United States; United States Food and Drug Administration

2019