quinidine has been researched along with daunorubicin in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Adachi, Y; Sugiyama, Y; Suzuki, H | 1 |
| Borchardt, RT; Horie, K; Tang, F | 2 |
| Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Boesch, D; Loor, F; Muller, K; Pourtier-Manzanedo, A | 1 |
| Bindslev, N; Demant, EJ; Friche, E; Jensen, PB; Sehested, M; Skovsgaard, T; Vindeløv, L | 1 |
| Havlick, MJ; Jackson, RC; Klohs, WD; Steinkampf, RW | 1 |
| Cardarelli, CO; Cornwell, MM; Gottesman, MM; Pastan, I; Willingham, MC | 1 |
| Herman, EH; Schein, P; Taylor, O; Waravdekar, VS | 1 |
| Cardarelli, C; Gottesman, MM; Pastan, I; Stein, WD | 1 |
| Adjei, A; Burke, PJ; Cheng, YC; Donehower, RC; Gore, SD; Grochow, LB; Jones, RJ; Kaufmann, SH; Rowinsky, EK | 1 |
| Futai, M; Manabe, T; Moriyama, Y; Tashiro, Y; Yoshimori, T | 1 |
| Algour, N; Ayesh, S; Lyubimov, E; Stein, WD | 1 |
| Asashi, S; Higuchi, T; Katoh, M; Suzuyama, N; Takeuchi, T; Yokoi, T; Yoshitomi, S | 1 |
1 review(s) available for quinidine and daunorubicin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for quinidine and daunorubicin
| Article | Year |
|---|---|
Phase I and pharmacodynamic study of the topoisomerase I-inhibitor topotecan in patients with refractory acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Camptothecin; Daunorubicin; Drug Administration Schedule; Drug Resistance, Multiple; Female; Follow-Up Studies; Humans; Immunohistochemistry; Leukemia; Male; Middle Aged; Mouth Mucosa; Quinidine; Remission Induction; Stomatitis; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
19 other study(ies) available for quinidine and daunorubicin
| Article | Year |
|---|---|
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection | 2001 |
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genes, MDR; Humans; Intestinal Mucosa; Transfection | 2002 |
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?
Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine | 2002 |
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative.
Topics: Amiodarone; Animals; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Flow Cytometry; Leukemia, Experimental; Leukemia, Myeloid; Microscopy, Fluorescence; Quinacrine; Quinidine; Tumor Cells, Cultured; Verapamil | 1991 |
Inhibition of vincristine binding to plasma membrane vesicles from daunorubicin-resistant Ehrlich ascites cells by multidrug resistance modulators.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Membrane; Daunorubicin; Drug Resistance; Polysorbates; Quinidine; Trifluoperazine; Tumor Stem Cell Assay; Verapamil; Vincristine | 1989 |
Resistance to anthrapyrazoles and anthracyclines in multidrug-resistant P388 murine leukemia cells: reversal by calcium blockers and calmodulin antagonists.
Topics: Animals; Anthracenes; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Transport; Calcium Channel Blockers; Calmodulin; Cell Line; Daunorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Naphthacenes; Polysorbates; Pyrazoles; Quinidine; Solubility; Structure-Activity Relationship | 1986 |
Single cell analysis of daunomycin uptake and efflux in multidrug-resistant and -sensitive KB cells: effects of verapamil and other drugs.
Topics: Biological Transport; Carcinoma; Cell Nucleus; Daunorubicin; Drug Resistance; Humans; KB Cells; Quinidine; Verapamil; Vinblastine; Vincristine | 1986 |
Effect of various antiarrhythmic drugs on the daunomycin-induced arrhythmia in the hamster.
Topics: Amino Alcohols; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cricetinae; Daunorubicin; Heart Rate; Lidocaine; Male; Phenytoin; Procaine; Propranolol; Quinidine; Sympatholytics | 1970 |
Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates.
Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carrier Proteins; Colchicine; Daunorubicin; Drug Resistance; Etoposide; Humans; Kinetics; Membrane Glycoproteins; Mice; Quinidine; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Vinblastine | 1994 |
ATP-dependent uptake of anti-neoplastic agents by acidic organelles.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Antineoplastic Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cells, Cultured; Chromaffin Granules; Daunorubicin; Drug Resistance; Hydrogen-Ion Concentration; Mice; Nigericin; Organelles; Proteolipids; Proton-Translocating ATPases; Quinidine; Reserpine; Valinomycin; Vanadates; Verapamil | 1994 |
Reversal of P-glycoprotein is greatly reduced by the presence of plasma but can be monitored by an ex vivo clinical assay.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Screening Assays, Antitumor; Humans; Kidney; Leukemia P388; Mice; Plasma; Quinidine; Verapamil; Vinblastine | 1996 |
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Digoxin; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Quinidine; Rats; Species Specificity; Verapamil | 2007 |