Compounds > quinidine
Page last updated: 2024-08-17

quinidine and dabigatran

quinidine has been researched along with dabigatran in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Hu, ZY; Zhao, Y1
George, S; Lewis, V; Taburyanskaya, M1
Marathe, P; Rodrigues, AD; Shen, H; Sinz, M; Yao, M; Zhu, M1
Costales, C; Eatemadpour, S; Kimoto, E; Lazzaro, S; Varma, MV; Yamazaki, S1
De Zwart, L; Evers, R; Yamazaki, S1

Other Studies

6 other study(ies) available for quinidine and dabigatran

ArticleYear
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate.
    British journal of pharmacology, 2014, Volume: 171, Issue:4

    Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil

2014
Probable drug-drug interaction between dabigatran and quinidine resulting in thrombin time rebound despite multiple idarucizumab doses.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2019, Volume: 30, Issue:1

    Topics: Acute Kidney Injury; Antibodies, Monoclonal, Humanized; Antithrombins; Blood Coagulation; Dabigatran; Drug Interactions; Hemorrhage; Humans; Quinidine; Thrombin Time

2019
Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins.
    Molecular pharmaceutics, 2019, 09-03, Volume: 16, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Dabigatran; Dogs; Drug Interactions; HEK293 Cells; Humans; Inhibitory Concentration 50; Ketoconazole; Madin Darby Canine Kidney Cells; Octamer Transcription Factor-1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Quinidine; Renal Elimination; Transfection; Verapamil

2019
Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein Induction.
    CPT: pharmacometrics & systems pharmacology, 2019, Volume: 8, Issue:9

    Topics: Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dabigatran; Digoxin; Drug Interactions; Female; Gene Expression Regulation; Healthy Volunteers; Humans; Intestinal Mucosa; Male; Models, Biological; Propanolamines; Quinidine; Rifampin

2019
Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition.
    CPT: pharmacometrics & systems pharmacology, 2022, Volume: 11, Issue:1

    Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Computer Simulation; Dabigatran; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestines; Itraconazole; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Quinidine; Verapamil; Young Adult

2022