quinidine has been researched along with colchicine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.57) | 18.7374 |
| 1990's | 8 (22.86) | 18.2507 |
| 2000's | 13 (37.14) | 29.6817 |
| 2010's | 11 (31.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Thakker, DR; Troutman, MD | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Koivuniemi, A; Venho, VM | 1 |
| Abraham, I; Chauhan, SS; Chin, KV; Gottesman, MM; Krolczyk, AJ; Pastan, I; Sampson, KE; Schimmer, B; Wong, M | 1 |
| de Lannoy, IA; Silverman, M | 1 |
| Cereijido, M; Lázaro, A; Pasantes-Morales, H; Sánchez Olea, R | 1 |
| Jesuś García, J; Pasantes-Morales, H; Sánchez Olea, R | 1 |
| Smith, GH | 1 |
| Croop, JM; Kronauge, JF; Piwnica-Worms, D; Rao, VV | 1 |
| Aksentijevich, I; Cardarelli, CO; Gottesman, MM; Pastan, I | 1 |
| Cardarelli, C; Gottesman, MM; Pastan, I; Stein, WD | 1 |
| Miranda, D; Morán, J; Pasantes-Morales, H; Sánchez Olea, R | 1 |
| Bible, KC; Boerner, SA; Kaufmann, SH; Tourne, ME | 1 |
| CROSBY, WH; KAUFMAN, RM | 1 |
| Cisternino, S; Debray, M; Rousselle, C; Scherrmann, JM | 1 |
| Amidon, GL; Dahan, A | 1 |
| Pollack, GM; Zhao, R | 1 |
1 review(s) available for quinidine and colchicine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
34 other study(ies) available for quinidine and colchicine
| Article | Year |
|---|---|
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effect of colchicine on drug absorption from the rat small intestine in situ and in vitro.
Topics: Animals; Colchicine; Female; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Isoniazid; Quinidine; Rats; Sulfisoxazole | 1978 |
Reduced mRNA levels for the multidrug-resistance genes in cAMP-dependent protein kinase mutant cell lines.
Topics: Adrenal Glands; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cells, Cultured; Colchicine; Cricetinae; Cricetulus; Cyclic AMP; Cytotoxins; Female; Membrane Glycoproteins; Mice; Molecular Sequence Data; Mutation; Ovary; Polymerase Chain Reaction; Precipitin Tests; Protein Kinases; Quinidine; RNA, Messenger; Steroids; Transcription, Genetic; Transfection; Verapamil | 1992 |
The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Resistance; Kinetics; Membrane Glycoproteins; Quinidine; Verapamil; Vinblastine | 1992 |
Osmolarity-sensitive release of free amino acids from cultured kidney cells (MDCK).
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acids; Calcium Channels; Cell Line; Colchicine; Cytochalasin B; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Potassium Channels; Quinidine; Taurine; Temperature; Water-Electrolyte Balance | 1991 |
Taurine release associated to volume regulation in rabbit lymphocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acids; Animals; Calcimycin; Colchicine; Cytochalasin B; Furosemide; Hypotonic Solutions; Ion Channels; Lymphocytes; Quinidine; Rabbits; Taurine; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Case studies of a clinical pharmacist.
Topics: Aged; Alcoholism; Allopurinol; Arrhythmias, Cardiac; Chloral Hydrate; Colchicine; Digoxin; Drug Synergism; Gastrointestinal Hemorrhage; Gout; Hospitals, Teaching; Humans; Liver Diseases; Male; Middle Aged; Nitroglycerin; Patient Care Team; Pharmacists; Pharmacy Service, Hospital; Quinidine; Warfarin; Washington | 1972 |
Characterization of multidrug resistance P-glycoprotein transport function with an organotechnetium cation.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Cations; Cell Survival; Cells, Cultured; Colchicine; Cricetinae; Dose-Response Relationship, Drug; Doxorubicin; Humans; Kinetics; Lipid Bilayers; Pharmaceutical Preparations; Phloretin; Prazosin; Quinidine; Technetium Tc 99m Sestamibi; Tetraphenylborate | 1995 |
Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carrier Proteins; Cell Death; Cell Survival; Colchicine; Cyclosporine; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Membrane Glycoproteins; Mice; Phenotype; Point Mutation; Quinidine; Transfection; Verapamil | 1995 |
Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates.
Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carrier Proteins; Colchicine; Daunorubicin; Drug Resistance; Etoposide; Humans; Kinetics; Membrane Glycoproteins; Mice; Quinidine; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Vinblastine | 1994 |
Volume regulation in NIH/3T3 cells not expressing P-glycoprotein. I. Regulatory volume decrease.
Topics: 3T3 Cells; 4-Aminopyridine; Animals; Anions; ATP Binding Cassette Transporter, Subfamily B, Member 1; Barium; Cell Membrane Permeability; Chloride Channels; Chlorides; Colchicine; Colforsin; Dipyridamole; Gramicidin; Kinetics; Mice; Niflumic Acid; Nitrobenzoates; Potassium Channel Blockers; Potassium Channels; Quinidine; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Water-Electrolyte Balance | 1997 |
Effect of P-glycoprotein on flavopiridol sensitivity.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; CHO Cells; Cisplatin; Colchicine; Colony-Forming Units Assay; Cricetinae; Drug Resistance, Multiple; Flavonoids; Paclitaxel; Piperidines; Quinidine; Verapamil | 2001 |
DRUG-INDUCED THROMBOCYTOPENIA.
Topics: Acetazolamide; Anticonvulsants; Arsphenamine; Chloramphenicol; Chlorothiazide; Colchicine; Gold; Hydantoins; Hypoglycemic Agents; Meprobamate; Perchlorates; Phenothiazines; Phenylbutazone; Pyrimethamine; Quinacrine; Quinidine; Quinine; Ristocetin; Streptomycin; Sulfonamides; Thrombocytopenia; Toxicology | 1964 |
In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Colchicine; Cyclosporins; Dexamethasone; Drug Interactions; Male; Mice; Mice, Inbred Strains; Morphine; Progesterone; Quinidine; Verapamil; Vinblastine | 2004 |
Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beverages; Caco-2 Cells; Cell Polarity; Citrus paradisi; Colchicine; Dose-Response Relationship, Drug; Flavanones; Food-Drug Interactions; Fruit; Furocoumarins; Humans; Ileum; Intestinal Absorption; Jejunum; Male; Permeability; Quinidine; Rats; Rats, Wistar; Risk Assessment; Time Factors; Tubulin Modulators; Verapamil | 2009 |
Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: a quantitative analysis of regional drug exposure in the brain.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Calcium Channel Blockers; Capillaries; Colchicine; Dose-Response Relationship, Drug; Infusions, Subcutaneous; Inulin; Least-Squares Analysis; Linear Models; Loperamide; Mice; Mice, Inbred Strains; Mice, Knockout; Microdissection; Perfusion; Quinidine; Regional Blood Flow; Substrate Specificity; Verapamil | 2009 |