Page last updated: 2024-08-17

quinidine and cimetidine

quinidine has been researched along with cimetidine in 92 studies

Research

Studies (92)

Timeframe	Studies, this research(%)	All Research%
pre-1990	20 (21.74)	18.7374
1990's	17 (18.48)	18.2507
2000's	33 (35.87)	29.6817
2010's	20 (21.74)	24.3611
2020's	2 (2.17)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Dresser, MJ; Giacomini, KM; Gray, AT; Terashita, S; Yost, SC; Zhang, L	1
Inui, KI; Ito, T; Tanaka, K; Yano, I	1
Giacomini, KM; Schaner, ME; Zhang, L	1
Inui, KI; Masuda, S; Okuda, M; Saito, H; Urakami, Y	1
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Topliss, JG; Yoshida, F	1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Adachi, Y; Sugiyama, Y; Suzuki, H	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Akazawa, M; Inui, K; Okuda, M; Saito, H; Urakami, Y	1
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A	1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ	1
Engel, K; Wang, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Wang, J	1
Guo, HF; Jin, J; Li, ZR; Liu, ZY; Xie, ZS; Xue, ST; Yi, H; Zhang, L	1
Domínguez-Gil, A; Lanao, JM; Sayalero, ML; Vicente, MT	1
Bentur, Y; Cheung, D; Klein, J; Koren, G; Moselhy, G	1
Babin-Ebell, J; Russ, H; Schömig, E; Schönfeld, CL; Trendelenburg, U	1
Biollaz, J; Munafo, A; Reymond-Michel, G	1
Blinkov, IL; Bogovskiĭ, BP; Kharlamova, IV; Rubin, MP; Sivkov, II; Starodubtsev, AK	1
Kawamata, Y; Nishigaki, R; Shibasaki, S; Umemura, K	1
DeLeon, C; McKinney, TD; Speeg, KV	1
Hardy, BG; Schentag, JJ	1
Gon, S; Komoriya, K; Matsuura, Y; Nishigaki, R; Shibasaki, S; Umemura, K	1
Chiang, HJ; Misawa, M; Suzuki, T	1
Fan Chiang, HJ; Misawa, M; Suzuki, T; Yanaura, S	1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y; Suzuki, H	1
Kunnemann, ME; McKinney, TD	1
Piepho, RW	1
McKinney, TD; Speeg, KV	1
Ascensao, JL; Flynn, PJ; Jacob, HS; Slungaard, A; Wachsman, W; Zanjani, ED	1
Fox, T; Garnett, WR; Kline, BJ; Kolb, KW; Small, RE; Vetrovec, GW	1
Boudoulas, H; MacKichan, JJ; Schaal, SF; Stine, RA	1
D'Arcy, PF	1
Golden, L; Hardy, BG; Lalka, D; Schentag, JJ; Zador, IT	1
DiGregorio, GJ; Fruncillo, RJ; Soll, A	1
Branch, RA; Fitzgerald, GA; Polish, LB	1
Hartwig, W	1
Collins, JM; Jamis-Dow, CA; Katki, AG; Klecker, RW	1
Buters, JT; Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC	1
Bendayan, R; Lo, B; Silverman, M	1
Gibaldi, M	1
Inui, K; Okuda, M; Saito, H; Takano, M; Urakami, Y	1
Inui, K; Nakamura, T; Takano, M; Yasuhara, M	1
Aster, RH; Curtis, BR; Gentilini, G	1
Hanada, K; Kato, T; Kinami, J; Ogata, H; Takubo, T	1
Fukada, A; Inui, KI; Ohnishi, S; Saito, H	1
Bigler, L; Follath, F; Ha, HR; Kozlik, P; Stieger, B	1
Haehner, T; Müller-Enoch, D; Refaie, MO	1
O'Donnell, MJ; Rheault, MR	1
Bijelic, G; Kim, NR; O'Donnell, MJ	1
O'Donnell, MJ; Plaumann, JS; Rheault, MR	1
Bellward, GD; Chang, TK; Levine, M; Madeira, M; Mirfazaelian, A	1
Inui, K; Katsura, T; Masuda, S; Sato, T; Tanihara, Y; Yonezawa, A	1
Iwatsubo, T; Kamimura, H; Noguchi, K; Umehara, KI; Usui, T	1
Hashimoto, Y; Kagawa, Y; Taguchi, M; Tahara, K; Takaai, M	1
Boralli, VB; Coelho, EB; Lanchote, VL	1
Di Nardo, G; Ferrero, S; Gilardi, G; Sadeghi, SJ	1
Jung, JA; Parvez, MM; Shin, HJ; Shin, JG	1
Adam, AMA; Al-Humaidi, JY; Eldaroti, HH; Hegab, MS; Refat, MS; Saad, HA	1
Contreras, D; García, MA; González, PM	1

Reviews

5 review(s) available for quinidine and cimetidine

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The plasma membrane monoamine transporter (PMAT): Structure, function, and role in organic cation disposition. Clinical pharmacology and therapeutics, 2016, Volume: 100, Issue:5 Topics: Animals; Biogenic Amines; Humans; Plasma Membrane Neurotransmitter Transport Proteins; Xenobiotics	2016
Individualization of calcium entry-blocker dosage for systemic hypertension. The American journal of cardiology, 1985, Dec-06, Volume: 56, Issue:16 Topics: Adult; Age Factors; Aged; Calcium Channel Blockers; Child; Cimetidine; Diabetes Complications; Digoxin; Drug Interactions; Female; Humans; Hypertension; Kidney Diseases; Kinetics; Lactation; Liver Diseases; Middle Aged; Pregnancy; Quinidine; Smoking	1985
Stereoselective and isozyme-selective drug interactions. Chirality, 1993, Volume: 5, Issue:6 Topics: Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Isoenzymes; Quinidine; Rifampin; Stereoisomerism; Warfarin	1993

Other Studies

87 other study(ies) available for quinidine and cimetidine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Cloning and functional expression of a human liver organic cation transporter. Molecular pharmacology, 1997, Volume: 51, Issue:6 Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Liver; Membrane Proteins; Molecular Sequence Data; Oocytes; Organic Cation Transporter 1; Polymerase Chain Reaction; Rats; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Tissue Distribution; Xenopus laevis	1997
Transport of quinolone antibacterial drugs by human P-glycoprotein expressed in a kidney epithelial cell line, LLC-PK1. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2 Topics: Animals; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Epithelial Cells; Epithelium; Fluoroquinolones; Humans; Kidney; Levofloxacin; LLC-PK1 Cells; Ofloxacin; Quinolones; Swine	1997
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection	1998
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2 Topics: Animals; Base Sequence; Carrier Proteins; Cations; Cell Line; Cell Membrane; DNA Primers; Dogs; Kidney Tubules; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Tetraethylammonium	1998
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2 Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis	1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Molecular pharmacology, 2001, Volume: 59, Issue:5 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis	2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein. Pharmaceutical research, 2001, Volume: 18, Issue:12 Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney. Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:7 Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Cations; Cell Line; Cloning, Molecular; DNA, Complementary; Genetic Variation; Humans; Kidney; Molecular Sequence Data; Organic Cation Transport Proteins; Organic Cation Transporter 2; Tetraethylammonium; Tissue Distribution; Transfection	2002
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine	2003
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharmaceutical research, 2003, Volume: 20, Issue:4 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Interaction of organic cations with a newly identified plasma membrane monoamine transporter. Molecular pharmacology, 2005, Volume: 68, Issue:5 Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cell Line; Dogs; Equilibrative Nucleoside Transport Proteins; Humans; Membrane Transport Proteins; Nerve Tissue Proteins; Organic Cation Transport Proteins; Tyramine	2005
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Determination of log D via automated microfluidic liquid-liquid extraction. Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16 Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties. European journal of medicinal chemistry, 2020, Aug-15, Volume: 200 Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes; Zebrafish	2020
A computer program (DCN) for numerical convolution and deconvolution of pharmacokinetic functions. Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:5 Topics: Algorithms; Cimetidine; Pharmacokinetics; Quinidine; Software	1992
Renal handling of cisplatin: interactions with organic anions and cations in the dog. Clinical and investigative medicine. Medecine clinique et experimentale, 1991, Volume: 14, Issue:5 Topics: Animals; Anions; Blood Proteins; Cations; Cimetidine; Cisplatin; Dogs; Glomerular Filtration Rate; Kidney; Kidney Tubules; Metabolic Clearance Rate; Probenecid; Protein Binding; Quinidine; Ranitidine	1991
Human Caki-1 cells are the first model for extraneuronal transport of noradrenaline (uptake2) which is based on a clonal cell line. Journal of neural transmission. Supplementum, 1990, Volume: 32 Topics: Animals; Cell Line; Cimetidine; Clone Cells; Corticosterone; Humans; Isoproterenol; Kidney; Lymphocytes; Mice; Models, Biological; Muscles; Neurons; Norepinephrine; Opossums; Procainamide; Quinidine; Rabbits; Rats	1990
Altered flecainide disposition in healthy volunteers taking quinine. European journal of clinical pharmacology, 1990, Volume: 38, Issue:3 Topics: Adult; Biotransformation; Cimetidine; Drug Interactions; Electrocardiography; Flecainide; Half-Life; Heart Rate; Humans; Male; Quinidine; Quinine; Reference Values	1990
[Treatment of arrhythmia in patients with chronic ischemic heart disease using kinilentin combined with an inhibitor or inductor of microsomal oxidation]. Sovetskaia meditsina, 1989, Issue:12 Topics: Arrhythmias, Cardiac; Benzhydryl Compounds; Cimetidine; Coronary Disease; Drug Therapy, Combination; Enzyme Induction; Female; Humans; Male; Microsomes, Liver; Middle Aged; Oxidation-Reduction; Quinidine	1989
Effects of cimetidine on quinidine distribution and tissue pH in rats. Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:6 Topics: Acid-Base Equilibrium; Animals; Blood Proteins; Cimetidine; Dimethadione; Drug Interactions; In Vitro Techniques; Male; Protein Binding; Quinidine; Rats; Rats, Inbred Strains; Tissue Distribution	1989
Organic cation uptake by a cultured renal epithelium. Journal of cellular physiology, 1988, Volume: 137, Issue:3 Topics: Animals; Azides; Biological Transport; Cell Line; Cimetidine; Epithelial Cells; Epithelium; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Kinetics; Quinidine; Sodium Azide; Temperature; Tetraethylammonium; Tetraethylammonium Compounds	1988
Lack of effect of cimetidine on the metabolism of quinidine: effect on renal clearance. International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:8 Topics: Adult; Biotransformation; Cimetidine; Drug Interactions; Humans; Male; Quinidine	1988
Effects of cimetidine on quinidine distribution in rats. Journal of pharmacobio-dynamics, 1987, Volume: 10, Issue:12 Topics: Animals; Blood Proteins; Cimetidine; Drug Interactions; Kinetics; Male; Protein Binding; Quinidine; Rats; Rats, Inbred Strains; Tissue Distribution	1987
Effects of quinidine and cimetidine on the methamphetamine level in the rat brain. Japanese journal of pharmacology, 1987, Volume: 43, Issue:1 Topics: Amphetamine; Animals; Brain; Cimetidine; Male; Methamphetamine; Quinidine; Rats; Rats, Inbred Strains	1987
Effects of quinidine and cimetidine on methamphetamine stereotypy in rats. Journal of pharmacobio-dynamics, 1987, Volume: 10, Issue:3 Topics: Animals; Cimetidine; Drug Interactions; Hydrogen-Ion Concentration; Male; Methamphetamine; Quinidine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Urine	1987
Transport of cimetidine by the rat choroid plexus in vitro. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3 Topics: Amino Acids; Animals; Biological Transport, Active; Choroid Plexus; Cimetidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Male; Mathematics; Oligopeptides; Penicillin G; Proline; Quinidine; Quinine; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid	1986
Cimetidine transport in rabbit renal cortical brush-border membrane vesicles. The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2 Topics: Animals; Biological Transport, Active; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cimetidine; Female; Hydrogen-Ion Concentration; Kidney Cortex; Microvilli; Osmolar Concentration; Probenecid; Procainamide; Quinidine; Rabbits; Tetraethylammonium Compounds; Valinomycin	1987
Cimetidine and procainamide secretion by proximal tubules in vitro. The American journal of physiology, 1982, Volume: 242, Issue:6 Topics: Absorption; Acecainide; Animals; Carbon Dioxide; Chromatography, High Pressure Liquid; Cimetidine; Guanidines; Hypothermia; Kidney Tubules, Proximal; Kinetics; Ouabain; Probenecid; Procainamide; Quinidine; Rabbits	1982
Quinidine-induced neutropenia: report of a case with drug-dependent inhibition of granulocyte colony generation. Acta haematologica, 1984, Volume: 72, Issue:5 Topics: Agranulocytosis; Bone Marrow Examination; Cimetidine; Colony-Forming Units Assay; Granulocytes; Hematopoietic Stem Cells; Humans; Macrophages; Male; Middle Aged; Neutropenia; Quinidine	1984
Effect of cimetidine on quinidine clearance. Therapeutic drug monitoring, 1984, Volume: 6, Issue:3 Topics: Adult; Cimetidine; Drug Interactions; Electrocardiography; Half-Life; Heart Rate; Humans; Male; Quinidine	1984
Indocyanine green clearance following single and chronic cimetidine doses. Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:2 Topics: Adult; Cimetidine; Drug Administration Schedule; Female; Humans; Indocyanine Green; Kinetics; Liver; Male; Metabolic Clearance Rate; Propranolol; Quinidine; Regional Blood Flow	1984
Early reports on drug interactions. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2 Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine	1983
Effect of cimetidine on the pharmacokinetics and pharmacodynamics of quinidine. The American journal of cardiology, 1983, Volume: 52, Issue:1 Topics: Adult; Blood Proteins; Cimetidine; Drug Interactions; Electrocardiography; Guanidines; Humans; Kinetics; Male; Protein Binding; Quinidine	1983
Effect of cimetidine on the pharmacokinetics of quinidine and lidocaine in the rat. Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:7 Topics: Animals; Cimetidine; Drug Interactions; Guanidines; Kinetics; Lidocaine; Male; Quinidine; Rats; Rats, Inbred Strains	1983
Digitoxin-quinidine interaction: potentiation during administration of cimetidine. Southern medical journal, 1981, Volume: 74, Issue:5 Topics: Antacids; Cimetidine; Depression, Chemical; Digitoxin; Drug Synergism; Female; Guanidines; Humans; Middle Aged; Quinidine	1981
[Various therapeutic advances]. Polskie Archiwum Medycyny Wewnetrznej, 1981, Volume: 66, Issue:2 Topics: Anticoagulants; Cardiovascular Diseases; Cimetidine; Clofibrate; Digoxin; Narcotics; Peptic Ulcer; Prolactin; Quinidine; Vitamin D Deficiency; Yersinia Infections	1981
Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences. Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:2 Topics: Animals; Biotransformation; Cimetidine; Cytochrome P-450 Enzyme System; Dexamethasone; Diphenhydramine; Drug Evaluation, Preclinical; Drug Interactions; Glycerol; Humans; In Vitro Techniques; Ketoconazole; Kinetics; Liver; Microsomes, Liver; Paclitaxel; Quinidine; Rats; Species Specificity; Surface-Active Agents; Taxoids; Tritium	1995
CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers. The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10 Topics: Animals; Carbon Monoxide; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Ethinyl Estradiol; Humans; Kinetics; Mixed Function Oxygenases; Nifedipine; Protein Binding; Quinidine; Recombinant Proteins; Spodoptera; Substrate Specificity; Testosterone; Time Factors; Transfection; Warfarin	1995
Characterization of cimetidine transport in LLCPK1 cells. Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:1 Topics: Amiloride; Animals; Anti-Bacterial Agents; Azides; Biological Transport; Carrier Proteins; Cell Line; Cimetidine; Guanidine; Guanidines; Kidney; Macrolides; Microscopy, Fluorescence; Models, Biological; Niacinamide; Proton-Translocating ATPases; Quinidine; Quinine; Sodium Azide; Sodium-Hydrogen Exchangers; Swine; Tetraethylammonium; Tetraethylammonium Compounds	1994
cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2. Biochemical and biophysical research communications, 1996, Jul-16, Volume: 224, Issue:2 Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Blotting, Northern; Carrier Proteins; Cimetidine; Cloning, Molecular; DNA Primers; DNA, Complementary; Female; In Vitro Techniques; Kidney; Membrane Proteins; Molecular Sequence Data; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Polymerase Chain Reaction; Procainamide; Quinidine; Rats; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Tetraethylammonium; Tetraethylammonium Compounds; Xenopus laevis	1996
In-vivo clearance study of vancomycin in rats. The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:11 Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Cimetidine; Kidney; Male; Metabolic Clearance Rate; Probenecid; Quinidine; Rats; Rats, Wistar; Renal Agents; Vancomycin	1996
An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies. Blood, 1998, Oct-01, Volume: 92, Issue:7 Topics: Aged; Animals; Anti-Ulcer Agents; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases; Blood Platelets; CHO Cells; Cimetidine; Cricetinae; Cricetulus; Epitopes; Famotidine; Female; Flow Cytometry; Histamine H2 Antagonists; Humans; Molecular Structure; Nizatidine; Platelet Glycoprotein GPIb-IX Complex; Precipitin Tests; Protein Conformation; Quinidine; Quinine; Ranitidine; Recombinant Fusion Proteins; Structure-Activity Relationship; Thrombocytopenia; Transfection	1998
Effect of trimethoprim on the renal clearance of lamivudine in rats. The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:3 Topics: Animals; Anti-HIV Agents; Cimetidine; Drug Interactions; Glomerular Filtration Rate; Kidney; Lamivudine; Male; Metabolic Clearance Rate; Probenecid; Quinidine; Rats; Rats, Wistar; Time Factors; Trimethoprim	2000
Independent organic cation transport activity of Na(+)-L-carnitine cotransport system in LLC-PK(1) cells. American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:2 Topics: Animals; Carnitine; Carrier Proteins; Cations; Cell Line; Cell Polarity; Cephaloridine; Cephalosporins; Cimetidine; Enzyme Inhibitors; Epithelial Cells; Hydrogen-Ion Concentration; Ion Transport; Kidney Tubules, Proximal; Kinetics; Quinidine; Sodium; Swine; Tetraethylammonium	2001
Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone. Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:5 Topics: Amiodarone; Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ketoconazole; Kinetics; Microsomes, Liver; Midazolam; Models, Chemical; Oxidoreductases, N-Demethylating; Protein Isoforms; Quinidine; Rabbits; Rifampin; Time Factors	2001
Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system. Arzneimittel-Forschung, 2004, Volume: 54, Issue:1 Topics: Antifungal Agents; Antimalarials; Catalysis; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Estrogen Antagonists; Ethinyl Estradiol; Flavanones; Hormone Antagonists; Humans; Immunosuppressive Agents; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Mifepristone; NADPH-Ferrihemoprotein Reductase; Phospholipids; Quinidine; Quinine; Tacrolimus	2004
Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological methods. The Journal of experimental biology, 2004, Volume: 207, Issue:Pt 12 Topics: Animals; Biological Transport, Active; Cimetidine; Drosophila melanogaster; Electrophysiology; Ion Transport; Malpighian Tubules; Microelectrodes; Potassium; Quinidine; Tetraethylammonium; Tetraphenylborate; Verapamil; Vinblastine	2004
Effects of dietary or injected organic cations on larval Drosophila melanogaster: mortality and elimination of tetraethylammonium from the hemolymph. Archives of insect biochemistry and physiology, 2005, Volume: 60, Issue:2 Topics: Animals; Biological Transport, Active; Cations; Cimetidine; Diet; Dose-Response Relationship, Drug; Drosophila melanogaster; Hemolymph; Larva; Lethal Dose 50; Malpighian Tubules; Quinidine; Survival Rate; Temperature; Tetraethylammonium	2005
Tetraethylammonium and nicotine transport by the Malpighian tubules of insects. Journal of insect physiology, 2006, Volume: 52, Issue:5 Topics: Animals; Biological Transport; Carbon Radioisotopes; Chromatography, Thin Layer; Cimetidine; Female; In Vitro Techniques; Insecta; Male; Malpighian Tubules; Niacinamide; Nicotine; Quinidine; Rhodnius; Tetraethylammonium; Time Factors	2006
The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4 Topics: Catalase; Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Humans; Kinetics; Microsomes, Liver; NADP; Oxidoreductases, O-Demethylating; Quinidine; Recombinant Proteins; Superoxide Dismutase; Triazoles	2004
Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1. Biochemical pharmacology, 2008, Oct-01, Volume: 76, Issue:7 Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cell Line; Cimetidine; Dogs; Humans; Metformin; Octamer Transcription Factor-1; Organic Cation Transport Proteins; Organic Cation Transporter 2; Procainamide; Quinidine; Tetraethylammonium; Transfection	2008
Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions. Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:9 Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Benzamides; Cations; Cell Line; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Isoquinolines; Lidocaine; Metformin; Organic Cation Transport Proteins; Procainamide; Quinidine; Rats	2008
Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 Cells. Drug metabolism and pharmacokinetics, 2008, Volume: 23, Issue:5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bisoprolol; Cells, Cultured; Cimetidine; LLC-PK1 Cells; Organic Cation Transport Proteins; Quinidine; Swine; Tetraethylammonium	2008
Influence of quinidine, cimetidine, and ketoconazole on the enantioselective pharmacokinetics and metabolism of metoprolol in rats. Chirality, 2009, Volume: 21, Issue:10 Topics: Adrenergic beta-Antagonists; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Cimetidine; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Fasting; Hydrogen-Ion Concentration; Ketoconazole; Male; Metabolic Clearance Rate; Metoprolol; Molecular Structure; Quinidine; Rats; Rats, Wistar; Spectrometry, Fluorescence; Stereoisomerism	2009
Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4. Bioelectrochemistry (Amsterdam, Netherlands), 2012, Volume: 86 Topics: Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diclofenac; Drug Interactions; Electrochemical Techniques; Electrodes; Enzyme Inhibitors; Enzymes, Immobilized; Erythromycin; Inhibitory Concentration 50; Ketoconazole; Polyethylenes; Quaternary Ammonium Compounds; Quinidine	2012
Evaluation of Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:5 Topics: Aminosalicylic Acid; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cimetidine; Drug Interactions; HEK293 Cells; Humans; Ibuprofen; Liver-Specific Organic Anion Transporter 1; Naproxen; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 2; Probenecid; Proton Pump Inhibitors; Quinidine; Rifampin; Verapamil	2017
Measurements and correlations in solution-state for charge transfer products caused from the 1:2 complexation of TCNE acceptor with several important drugs. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2019, Mar-15, Volume: 211 Topics: Acetonitriles; Atenolol; Cimetidine; Ethylenes; Levofloxacin; Nitriles; Pharmaceutical Preparations; Quinidine; Reserpine; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thermodynamics	2019
Metformin Transport in Native MDCK-Wt and MDCK-II Monolayers Unveils Functional Inter-Strains Differences Influencing Drug Permeability. Pharmaceutical research, 2020, Jun-08, Volume: 37, Issue:7 Topics: Animals; Biofilms; Biological Transport; Cell Adhesion; Cells, Cultured; Cimetidine; Diffusion; Dogs; Humans; Hydrogen-Ion Concentration; Lopinavir; Madin Darby Canine Kidney Cells; Metformin; Pyrimethamine; Quinidine	2020