Page last updated: 2024-08-17

quinidine and bupivacaine

quinidine has been researched along with bupivacaine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19905 (22.73)18.7374
1990's2 (9.09)18.2507
2000's7 (31.82)29.6817
2010's8 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bedoya, M; Decher, N; González, W; Kiper, AK; Ramírez, D; Rinné, S1
Clarkson, CW; Hondeghem, LM1
Wood, M1
Ghoneim, MM; Pandya, H1
Lalka, D; McNamara, PJ; Pieper, JA; Slaughter, RL; Wyman, MG1
Chemtob, S; Deng, XF; Mulay, S; Varma, DR1
Chavez, RA; Forsayeth, JR; Gray, AT; Harada, M; Kindler, CH; Leonoudakis, D; Taylor, DM; Winegar, BD; Yost, CS1
Buckler, KJ; Honore, E; Williams, BA1
Arias, C; Caballero, R; Delpón, E; González, T; Moreno, I; Navarro-Polanco, R; Tamargo, J; Tamkun, MM; Valenzuela, C1
Asada, A; Funao, T; Oda, Y; Tanaka, K1
Chen, YW; Cheng, KI; Chu, CC; Chu, KS; Huang, KL; Tzeng, JI; Wang, JJ1
Cohen, NA; Kreindler, JL; Wilber, M; Xiong, G; Zhao, KQ1
Chen, YC; Chen, YW; Chu, CC; Leung, YM; Wang, JJ1
Breton, JD; Stuart, GJ1

Reviews

2 review(s) available for quinidine and bupivacaine

ArticleYear
TASK Channels Pharmacology: New Challenges in Drug Design.
    Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22

    Topics: Animals; Drug Design; Drug Discovery; Humans; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Tandem Pore Domain

2019
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors

1986

Other Studies

20 other study(ies) available for quinidine and bupivacaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Evidence for a specific receptor site for lidocaine, quinidine, and bupivacaine associated with cardiac sodium channels in guinea pig ventricular myocardium.
    Circulation research, 1985, Volume: 56, Issue:4

    Topics: Animals; Bupivacaine; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Kinetics; Lidocaine; Male; Membrane Potentials; Models, Biological; Myocardial Contraction; Myocardium; Papillary Muscles; Quinidine; Receptors, Drug

1985
Plasma protein binding of bupivacaine and its interaction with other drugs in man.
    British journal of anaesthesia, 1974, Volume: 46, Issue:6

    Topics: Atropine; Binding, Competitive; Blood Proteins; Bupivacaine; Desipramine; Dialysis; Drug Interactions; Heparin; Humans; Meperidine; Phenytoin; Protein Binding; Quinidine

1974
Factors influencing serum protein binding of lidocaine in humans.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:6

    Topics: Acecainide; Blood Proteins; Bupivacaine; Disopyramide; Humans; Lidocaine; Orosomucoid; Procainamide; Propranolol; Protein Binding; Quinidine; Serum Albumin

1981
Mechanisms of the atrium-specific positive inotropic activities of quinidine- and atropine-like agents in rats.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Bupivacaine; Catecholamines; Dimethylphenylpiperazinium Iodide; Disopyramide; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stimulation, Chemical

1997
An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Feb-01, Volume: 18, Issue:3

    Topics: Acids; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Barium; Blotting, Northern; Bupivacaine; Central Nervous System Depressants; Cerebellum; Cloning, Molecular; Ethanol; Ion Channel Gating; Lidocaine; Magnesium; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Peptides; Phenytoin; Phosphorylation; Potassium Channels; Quinidine; Rats; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tetraethylammonium; Xenopus; Zinc

1998
An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells.
    The Journal of physiology, 2000, May-15, Volume: 525 Pt 1

    Topics: Acidosis; Anesthetics; Animals; Barium; Bupivacaine; Carotid Arteries; Cells, Cultured; Chemoreceptor Cells; Halothane; Hydrogen-Ion Concentration; In Situ Hybridization; Nerve Tissue Proteins; Oxygen; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Tandem Pore Domain; Quinidine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Zinc

2000
Assembly with the Kvbeta1.3 subunit modulates drug block of hKv1.5 channels.
    Molecular pharmacology, 2002, Volume: 62, Issue:6

    Topics: Anesthetics, Local; Bupivacaine; Cells, Cultured; Electrophysiology; Humans; Kv1.3 Potassium Channel; Kv1.5 Potassium Channel; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Transfection

2002
The P-glycoprotein inhibitor quinidine decreases the threshold for bupivacaine-induced, but not lidocaine-induced, convulsions in rats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:8

    Topics: Anesthetics, Local; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Gas Analysis; Brain; Bupivacaine; Chromatography, High Pressure Liquid; Hemodynamics; Hydrogen-Ion Concentration; Lidocaine; Male; Quinidine; Rats; Rats, Sprague-Dawley; Seizures

2003
The cutaneous analgesic effect of class I antiarrhythmic drugs.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Analgesics; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Bupivacaine; Dose-Response Relationship, Drug; Flecainide; Injections, Subcutaneous; Lidocaine; Male; Mexiletine; Pain Measurement; Pain Threshold; Quinidine; Rats; Rats, Sprague-Dawley; Reflex; Skin; Sodium Channel Blockers; Time Factors

2007
A role for two-pore K⁺ channels in modulating Na⁺ absorption and Cl⁻ secretion in normal human bronchial epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Absorption; Amiloride; Bronchi; Bupivacaine; Cell Line; Cell Polarity; Chlorides; Colforsin; Epithelial Cells; Humans; Immunohistochemistry; Ion Transport; Potassium Channel Blockers; Potassium Channels, Tandem Pore Domain; Quinidine; Respiratory Mucosa; Sodium

2012
Spinal blockades of class I antiarrythmic drugs with bupivacaine by isobolographic analysis in rats.
    Neuroscience letters, 2012, Oct-18, Volume: 528, Issue:1

    Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Bupivacaine; Dose-Response Relationship, Drug; Flecainide; Injections, Spinal; Male; Mexiletine; Quinidine; Rats; Rats, Sprague-Dawley

2012
GABA
    The European journal of neuroscience, 2017, Volume: 46, Issue:12

    Topics: Animals; Bee Venoms; Bupivacaine; CA1 Region, Hippocampal; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA-B Receptor Antagonists; Male; Neocortex; Potassium Channel Blockers; Pyramidal Cells; Quinidine; Rats; Rats, Wistar; Receptors, GABA-B

2017