Page last updated: 2024-08-17

quinidine and bumetanide

quinidine has been researched along with bumetanide in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's7 (25.00)18.2507
2000's8 (28.57)29.6817
2010's11 (39.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brown, RD; Feldman, AM1
Butt, AG; Clapp, WL; Frizzell, RA1
Beuerlein, G; Dharmsathaphorn, K; McRoberts, JA1
Cittadini, A; Di Francesco, A; Wolf, FI1
Guo, X; Hopfer, U; Laboisse, CL; Merlin, D1
Martinez, A; Moran, J; Pasantes-Morales, H; Sanchez-Olea, R1
Ehrenfeld, J; Ratcliff, FG1
Coca-Prados, M; Delamere, NA; Mito, T1
Geada, MM; Singh, J; Wisdom, DM1
Avella, M; Duranton, C; Mikulovic, E; Poujeol, P; Tauc, M1

Reviews

3 review(s) available for quinidine and bumetanide

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacology of hearing and ototoxicity.
    Annual review of pharmacology and toxicology, 1978, Volume: 18

    Topics: Adrenal Glands; Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bumetanide; Cochlea; Environmental Pollutants; Erythromycin; Ethacrynic Acid; Female; Furosemide; Guinea Pigs; Hearing; Hearing Disorders; Humans; Kidney; Ovary; Quinidine; Quinine; Seizures; Thyroid Gland

1978

Other Studies

25 other study(ies) available for quinidine and bumetanide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Potassium conductances in tracheal epithelium activated by secretion and cell swelling.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1

    Topics: Amphotericin B; Animals; Barium; Bumetanide; Cell Membrane; Chlorides; Dogs; Electric Conductivity; Epinephrine; Epithelium; In Vitro Techniques; Kinetics; Mucous Membrane; Ouabain; Potassium; Potassium Channels; Quinidine; Rubidium; Trachea

1990
Cyclic AMP and Ca2+-activated K+ transport in a human colonic epithelial cell line.
    The Journal of biological chemistry, 1985, Nov-15, Volume: 260, Issue:26

    Topics: Adenosine Triphosphate; Anions; Barium; Biological Transport; Bucladesine; Bumetanide; Calcimycin; Calcium; Cell Line; Cell Membrane; Colonic Neoplasms; Cyclic AMP; Epithelium; Humans; Hydrogen-Ion Concentration; Kinetics; Ouabain; Potassium; Quinidine; Radioisotopes; Rubidium; Vasoactive Intestinal Peptide

1985
Characterization of magnesium efflux from Ehrlich ascites tumor cells.
    Archives of biochemistry and biophysics, 1994, Feb-01, Volume: 308, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Amiloride; Animals; Antimycin A; Bucladesine; Bumetanide; Calcimycin; Carcinoma, Ehrlich Tumor; Colforsin; Cyclic AMP; Energy Metabolism; Glucose; Homeostasis; Imipramine; Kinetics; Magnesium; Mice; Ouabain; Quinidine; Rotenone; Time Factors; Tumor Cells, Cultured

1994
Ca2+ and cAMP activate different K+ conductances in the human intestinal goblet cell line HT29-Cl.16E.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Amphotericin B; Barium; Bumetanide; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Digitonin; Diphenylamine; Electric Conductivity; Epithelial Cells; Epithelium; Fura-2; Humans; Intestinal Mucosa; Membrane Potentials; Models, Biological; Ouabain; Potassium; Potassium Channels; Quinidine; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoactive Intestinal Peptide

1995
Volume-activated Rb+ transport in astrocytes in culture.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Astrocytes; Biological Transport, Active; Bumetanide; Cells, Cultured; Cerebellum; Chlorides; Culture Media; Ethylmaleimide; Furosemide; Gluconates; Gramicidin; Hypotonic Solutions; Kinetics; Nitrates; Osmolar Concentration; Quinidine; Rats; Rubidium; Temperature

1993
Activation of osmotically-activated potassium transporters after injection of mRNA from A6 cells in Xenopus oocytes.
    Biochimica et biophysica acta, 1994, Mar-23, Volume: 1190, Issue:2

    Topics: Animals; Biotransformation; Bumetanide; Carrier Proteins; Cell Line; Glyburide; Oocytes; Potassium; Quinidine; RNA, Messenger; Rubidium Radioisotopes; Transfection; Xenopus laevis

1994
Calcium-dependent regulation of cation transport in cultured human nonpigmented ciliary epithelial cells.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1

    Topics: Biological Transport; Bumetanide; Calcimycin; Calcium; Carrier Proteins; Cations; Cell Line, Transformed; Ciliary Body; Egtazic Acid; Epithelial Cells; Epithelium; Humans; Ouabain; Pigment Epithelium of Eye; Potassium Channels; Quinidine; Rubidium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Terpenes; Thapsigargin

1993
Characterization of a sodium-dependent magnesium efflux from magnesium-loaded rat pancreatic acinar cells.
    Experimental physiology, 1996, Volume: 81, Issue:3

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Biological Transport; Bumetanide; Choline; Dinitrophenols; Female; In Vitro Techniques; Lidocaine; Magnesium; Male; Ouabain; Pancreas; Quinidine; Rats; Rats, Sprague-Dawley; Time Factors

1996
Potassium channels in primary cultures of seawater fish gill cells. II. Channel activation by hypotonic shock.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:5

    Topics: Animals; Bass; Bumetanide; Calcium; Cell Membrane; Cell Size; Cells, Cultured; Electric Conductivity; Gadolinium; Gills; Hypotonic Solutions; Iodine Radioisotopes; Ionomycin; Kinetics; Mechanoreceptors; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Quinidine; Rubidium Radioisotopes; Thapsigargin

2000