Page last updated: 2024-08-17

quinidine and alprenolol

quinidine has been researched along with alprenolol in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199013 (41.94)18.7374
1990's0 (0.00)18.2507
2000's8 (25.81)29.6817
2010's9 (29.03)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Brincat, JP; Broccatelli, F; Carosati, E; Cruciani, G; Frosini, M; Kaatz, GW; Neri, A; Sabatini, S1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Norris, RM1
Schroeder, JS1
Himori, N; Izumi, A1
Wood, M1
Gettes, LS1
Singh, BN1
Gibson, DG1
Aberg, A; Ulvenstam, G; Vedin, A; Wilhelmsson, C1
Levi, GP; Proto, C; Quadri, A; Rovetta, A1
Heeg, E; Reuter, N1
Levi, GF; Proto, C1
Forsbeck, M; Olin, R; Stejskal, VD1
Bender, F1

Reviews

3 review(s) available for quinidine and alprenolol

ArticleYear
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors

1986
Beta adrenergic blocking drugs in the treatment of cardiac arrhythmias.
    Cardiovascular clinics, 1970, Volume: 2, Issue:2

    Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Drug Therapy, Combination; Heart Conduction System; Heart Rate; Humans; Isoproterenol; Myocardial Infarction; Oxprenolol; Physical Exertion; Propranolol; Quinidine; Receptors, Adrenergic; Sotalol; Tachycardia, Paroxysmal

1970
Pharmacodynamic properties of beta-adrenergic receptor blocking drugs in man.
    Drugs, 1974, Volume: 7, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Cardiac Output; Catecholamines; Glycolysis; Heart; Heart Conduction System; Heart Rate; Hemodynamics; Humans; Lipid Metabolism; Oxprenolol; Oxygen Consumption; Physical Exertion; Pindolol; Practolol; Propranolol; Quinidine; Receptors, Adrenergic; Regional Blood Flow; Renin; Structure-Activity Relationship; Vasomotor System

1974

Trials

1 trial(s) available for quinidine and alprenolol

ArticleYear
Clinical uses of calcium ion antagonists in arrhythmias.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:1-2

    Topics: Adult; Aged; Alprenolol; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Child, Preschool; Clinical Trials as Topic; Female; Gallopamil; Humans; Male; Propylamines; Quinidine; Tachycardia, Paroxysmal; Tiapamil Hydrochloride; Verapamil

1980

Other Studies

27 other study(ies) available for quinidine and alprenolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA.
    ACS medicinal chemistry letters, 2012, Mar-08, Volume: 3, Issue:3

    Topics:

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Prophylactic antiarrhythmic drugs after myocardial infarction.
    Drugs, 1976, Volume: 11, Issue:6

    Topics: Adrenergic beta-Antagonists; Age Factors; Alprenolol; Anti-Arrhythmia Agents; Humans; Middle Aged; Myocardial Infarction; Practolol; Quinidine; Recurrence

1976
Should premature ventricular beats be treated in the ambulatory patient? A protagonist's view.
    Cardiovascular clinics, 1977, Volume: 8, Issue:1

    Topics: Adult; Aged; Alprenolol; Ambulatory Care; Cardiac Complexes, Premature; Death, Sudden; Electrocardiography; Follow-Up Studies; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Procainamide; Quinidine; Risk; Tachycardia; Ventricular Fibrillation

1977
Change in automaticity of excised, sino-atrial node by alprenolol and its dextro isomer and several drugs injected into the sinus node artery of the dog.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 230, Issue:2

    Topics: Adenosine; Alprenolol; Animals; Calcium; Dogs; Female; Heart Rate; Injections, Intra-Arterial; Male; Nifedipine; Procaine; Propranolol; Quinidine; Sinoatrial Node; Stereoisomerism; Tetrodotoxin

1977
Clinical aspects of the anti-arrhythmic actions of beta-receptor blocking drugs. 2. Clinical pharmacology.
    The New Zealand medical journal, 1973, Dec-26, Volume: 78, Issue:505

    Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmias, Cardiac; Drug Therapy, Combination; Heart Failure; Humans; Oxprenolol; Pindolol; Practolol; Propranolol; Quinidine; Stereoisomerism; Structure-Activity Relationship

1973
[Indications for long term treatment of ventricular arrhythmias].
    Lakartidningen, 1974, Dec-11, Volume: 71, Issue:50

    Topics: Alprenolol; Arrhythmias, Cardiac; Death, Sudden; Digitalis Glycosides; Electrocardiography; Humans; Long-Term Care; Phenytoin; Practolol; Procainamide; Quinidine

1974
[Combination of beta-blockaders and quinidine in the treatment of atrial fibrillation. Electrocardiographic aspects after restoring the sinus rhythm].
    Giornale italiano di cardiologia, 1972, Volume: 2, Issue:2

    Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Arrhythmia, Sinus; Atrial Fibrillation; Drug Combinations; Electrocardiography; Humans; Propranolol; Propylamines; Quinidine; Sympatholytics

1972
[Action of antiarrhythmic and -receptor blocking drugs on functional refractory period and contractility of electrically stimulated guinea-pig atria].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 268, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Anti-Arrhythmia Agents; Atrial Function; Drug Interactions; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Phenytoin; Procainamide; Propranolol; Quinidine; Reserpine; Sparteine; Sympatholytics; Time Factors; Verapamil

1971
Combined treatment of atrial fibrillation with quinidine and beta-blockers.
    British heart journal, 1972, Volume: 34, Issue:9

    Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Atrial Fibrillation; Chronic Disease; Drug Combinations; Drug Synergism; Electrocardiography; Humans; Indoles; Propranolol; Quinidine; Sympatholytics; Time Factors

1972
Diagnosis of drug-induced occupational allergy by lymphocyte transformation test.
    Developments in toxicology and environmental science, 1983, Volume: 11

    Topics: Alprenolol; Ampicillin; Chlormethiazole; Dermatitis, Occupational; Drug Hypersensitivity; Humans; Lymphocyte Activation; Metoprolol; Occupational Diseases; Quinidine

1983