Page last updated: 2024-08-17

quinidine and alanine

quinidine has been researched along with alanine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Förster, W; Mentz, P; Schmidt, R1
Blackburn, MG; Ellis, SW; Harlow, J; Hayhurst, GP; Larsson, C; Lennard, MS; Lightfoot, T; Lim, CK; Mahling, J; Rowland-Yeo, K; Smith, G; Tucker, GT; Wolf, CR1
Bett, GC; Rasmusson, RL1
Flanagan, JU; Kemp, CA; Maréchal, JD; McLaughlin, LA; Paine, MJ; Roberts, GC; Sutcliffe, MJ; Ward, CJ; Wolf, CR1
Julínek, O; Lindner, W; Urbanová, M1
Leake, BF; Meiler, J; Roden, DM; Sanders, CR; Smith, JA; Yang, T1

Other Studies

7 other study(ies) available for quinidine and alanine

ArticleYear
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
[The effect of cardiovascular agents on amino acid aryl amidase].
    Die Pharmazie, 1973, Volume: 28, Issue:4

    Topics: Ajmaline; Alanine; Amides; Aminohydrolases; Animals; Anti-Arrhythmia Agents; Azo Compounds; Cardiac Glycosides; Humans; Propranolol; Quinidine; Rabbits; Strophanthins

1973
Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6.
    The Biochemical journal, 2000, Feb-01, Volume: 345 Pt 3

    Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalytic Domain; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Enzyme Inhibitors; Kinetics; Ligands; Metoprolol; Mutagenesis, Site-Directed; Oxidation-Reduction; Propranolol; Quinidine; Quinine; Serine; Substrate Specificity; Yeasts

2000
Inactivation and recovery in Kv1.4 K+ channels: lipophilic interactions at the intracellular mouth of the pore.
    The Journal of physiology, 2004, Apr-01, Volume: 556, Issue:Pt 1

    Topics: Alanine; Allosteric Regulation; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Cytoplasm; Female; Gene Deletion; Intracellular Fluid; Kv1.4 Potassium Channel; Molecular Conformation; Oocytes; Peptide Fragments; Permeability; Point Mutation; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Valine; Xenopus laevis

2004
Why is quinidine an inhibitor of cytochrome P450 2D6? The role of key active-site residues in quinidine binding.
    The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46

    Topics: Alanine; Aspartic Acid; Binding Sites; Binding, Competitive; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Humans; Kinetics; Mass Spectrometry; Mixed Function Oxygenases; Models, Molecular; Mutation; Oxidoreductases, O-Demethylating; Protein Binding; Protein Structure, Tertiary; Quinidine; Spectrophotometry; Substrate Specificity

2005
Study of stereoselective interactions of carbamoylated quinine and quinidine with 3,5-dinitrobenzoyl α-amino acids using VCD spectroscopy in the region of C−H stretching vibrations.
    Chirality, 2011, Volume: 23, Issue:4

    Topics: Absorption; Alanine; Amino Acids; Circular Dichroism; Dinitrobenzenes; Glycine; Hydrophobic and Hydrophilic Interactions; Isoleucine; Leucine; Quinidine; Quinine; Stereoisomerism; Valine; Vibration

2011
An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1.
    Molecular pharmacology, 2013, Volume: 83, Issue:2

    Topics: Alanine; Allosteric Regulation; Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Cysteine; Heart; Humans; KCNQ1 Potassium Channel; Models, Molecular; Mutagenesis, Site-Directed; Myocardium; Quinidine

2013