quinidine has been researched along with acridines in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiang, GH; Unger, SH | 1 |
| Baughman, TM; Bell, MG; Cao, J; Dantzig, AH; Ehlhardt, WJ; Elmquist, WF; Gruber, J; Kroin, JS; Law, KL; Norman, BH; Shepard, RL; Shih, C; Starling, JJ; Winter, MA | 1 |
| Booth, CL; Brouwer, KL; Brouwer, KR | 1 |
| Wright, SH; Wunz, TM | 1 |
| Andersen, R; Borchardt, RT; Chen, W; Nielsen, LH; Yang, JZ | 1 |
| Ayrton, A; Bentz, J; Ellens, H; Polli, JW; Tran, TT | 1 |
| Bourdet, DL; Thakker, DR | 1 |
| Bourdet, DL; Pollack, GM; Thakker, DR | 1 |
| Chiou, WL; Yao, HM | 1 |
| Padowski, JM; Pollack, GM | 1 |
| Dinter-Heidorn, H; Greupink, R; Koenderink, JB; Russel, FG; van den Broek, PH; van den Heuvel, JJ; Wittgen, HG | 1 |
| Kallem, R; Kulkarni, CP; Mahammad, SS; Mandlekar, S; Patel, D; Singh, SP; Sinz, M; Thakur, M | 1 |
| Ahmed, Z; Bentz, J; Ellens, H; Hidalgo, IJ; Li, J; Li, L; Lumen, AA; Meng, Z; Owen, A | 1 |
13 other study(ies) available for quinidine and acridines
| Article | Year |
|---|---|
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dibenzocycloheptenes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Isoquinolines; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Quinidine; Quinolines; Structure-Activity Relationship; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil | 1997 |
Effect of multidrug resistance modulators on the hepatobiliary disposition of doxorubicin in the isolated perfused rat liver.
Topics: Acridines; Animals; Antibiotics, Antineoplastic; Bile; Dimethyl Sulfoxide; Doxorubicin; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Half-Life; In Vitro Techniques; Isoquinolines; Liver; Male; Models, Biological; Quinidine; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines | 1998 |
Influence of substrate structure on substrate binding to the renal organic cation/H+ exchanger.
Topics: Acridines; Animals; Antiporters; Carbon Radioisotopes; Cations; Ephedrine; Ion Transport; Kidney Cortex; Microvilli; Molecular Structure; Nicotine; Pyridinium Compounds; Quinidine; Quinine; Quinolinium Compounds; Rabbits; Stereoisomerism; Structure-Activity Relationship; Tetraethylammonium | 1999 |
Evaluation of the permeation characteristics of a model opioid peptide, H-Tyr-D-Ala-Gly-Phe-D-Leu-OH (DADLE), and its cyclic prodrugs across the blood-brain barrier using an in situ perfused rat brain model.
Topics: Acridines; Algorithms; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Blood-Brain Barrier; Brain Chemistry; Chromatography, High Pressure Liquid; Diazepam; Enkephalin, Leucine-2-Alanine; GABA Modulators; In Vitro Techniques; Isoquinolines; Kinetics; Male; Mass Spectrometry; Perfusion; Prodrugs; Quinidine; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines | 2002 |
The steady-state Michaelis-Menten analysis of P-glycoprotein mediated transport through a confluent cell monolayer cannot predict the correct Michaelis constant Km.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carbamates; Cell Line; Cell Membrane Permeability; Computer Simulation; Dogs; Furans; Humans; Loperamide; Models, Biological; Pharmacokinetics; Quinidine; Reproducibility of Results; Sulfonamides; Tetrahydroisoquinolines | 2005 |
Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein.
Topics: 2,4-Dinitrophenol; Absorption; Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cations; Cell Membrane Permeability; Dose-Response Relationship, Drug; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Membrane Potentials; Organic Cation Transport Proteins; Quinidine; Ranitidine; Tetraethylammonium; Tetrahydroisoquinolines; Tritium; Uncoupling Agents | 2006 |
Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells.
Topics: Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cations; Cell Membrane Permeability; Histamine H2 Antagonists; Humans; Intestinal Absorption; Intestinal Mucosa; Kinetics; Models, Biological; Organic Cation Transport Proteins; Quinidine; Ranitidine; Tetrahydroisoquinolines | 2006 |
The complexity of intestinal absorption and exsorption of digoxin in rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Ileum; In Vitro Techniques; Intestinal Absorption; Jejunum; Male; Microvilli; Organic Anion Transporters; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Tetrahydroisoquinolines; Verapamil | 2006 |
Examination of the ability of the nasal administration route to confer a brain exposure advantage for three chemical inhibitors of P-glycoprotein.
Topics: Acridines; Administration, Intranasal; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Drug Delivery Systems; Mice; Quinidine; Rifampin; Tetrahydroisoquinolines | 2010 |
Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Blood-Brain Barrier; Blotting, Western; Cannabinoid Receptor Antagonists; Cell Line; Humans; Kinetics; Male; Neoplasm Proteins; Piperidines; Pyrazoles; Quinidine; Rats; Rats, Wistar; Rimonabant; Tandem Mass Spectrometry; Tetrahydroisoquinolines | 2012 |
A simplified protocol employing elacridar in rodents: a screening model in drug discovery to assess P-gp mediated efflux at the blood brain barrier.
Topics: Acridines; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Chromatography, Liquid; Cost-Benefit Analysis; Digoxin; Drug Design; Drug Interactions; Half-Life; Injections, Intravenous; Male; Mice; Propanolamines; Quinidine; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tetrahydroisoquinolines; Time Factors; Tissue Distribution | 2012 |
Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Cyclosporine; Digoxin; Dogs; Furans; Gene Expression; Humans; Ketoconazole; Kinetics; Loperamide; Madin Darby Canine Kidney Cells; Protein Binding; Quinidine; Sulfonamides; Tetrahydroisoquinolines; Vinblastine | 2013 |