Page last updated: 2024-08-17

quinidine and 2-hydroxydesipramine

quinidine has been researched along with 2-hydroxydesipramine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brøsen, K; Gram, LF; Kragh-Sørensen, P1
Brøsen, K; Gram, LF1
Dahlqvist, R; Dumont, E; Spina, E; Steiner, E1
Cotreau-Bibbo, MM; Duan, SX; Greenblatt, DJ; Harmatz, JS; Shader, RI; von Moltke, LL1

Other Studies

4 other study(ies) available for quinidine and 2-hydroxydesipramine

ArticleYear
Extremely slow metabolism of amitriptyline but normal metabolism of imipramine and desipramine in an extensive metabolizer of sparteine, debrisoquine, and mephenytoin.
    Therapeutic drug monitoring, 1991, Volume: 13, Issue:2

    Topics: Administration, Oral; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Thin Layer; Debrisoquin; Desipramine; Drug Interactions; Humans; Imipramine; Male; Mephenytoin; Phenotype; Quinidine; Sparteine

1991
Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine.
    European journal of clinical pharmacology, 1989, Volume: 37, Issue:2

    Topics: Adult; Dealkylation; Desipramine; Drug Interactions; Female; Half-Life; Humans; Hydroxylation; Imipramine; Male; Phenotype; Quinidine; Sparteine

1989
Inhibition of desipramine 2-hydroxylation by quinidine and quinine.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:5

    Topics: Adult; Desipramine; Drug Interactions; Female; Humans; Hydroxylation; Male; Quinidine; Quinine

1988
Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antidepressive Agents; Biotransformation; Desipramine; Drug Interactions; Haplorhini; Humans; Hydroxylation; In Vitro Techniques; Ketoconazole; Male; Mice; Microsomes, Liver; Quinidine; Rats; Selective Serotonin Reuptake Inhibitors; Species Specificity

1994