quinazolines has been researched along with verubulin in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baichwal, V; Cai, SX; Carlson, RO; Drewe, J; English, NM; Kasibhatla, S; Lukas, P; Pervin, A; Pleiman, CM; Roth, B; Sirisoma, N; Skvortsov, S; Skvortsova, I; Tseng, B | 1 |
| Anderson, MB; Cai, SX; Drewe, J; Jiang, S; Kasibhatla, S; Mather, G; Pervin, A; Pleiman, CM; Sirisoma, N; Tseng, B; Willardsen, JA; Zhang, H | 1 |
| Akerley, W; Chhabra, A; Evans, BA; Hong, DS; Kurzrock, R; Mather, GG; Schabel, MC; Swabb, EA; Tsimberidou, AM; Uehara, C; Warren, T; Woodland, DP | 1 |
| Lenihan, DJ; Subbiah, IM; Tsimberidou, AM | 1 |
| Aiken, RD; Akerley, WA; Beelen, AP; Colman, H; De Groot, JF; Evans, BA; Glantz, M; Grossmann, KF; Jensen, RL; Matsuoko, Y; Olsen, JJ; Olson, JJ; Yu, M | 1 |
| Biersack, B; Ficner, R; Mahal, K; Mueller, T; Resch, M; Schobert, R | 1 |
| Chamberlain, MC; Fadul, CE; Grimm, S; Kim, L; Phuphanich, S; Recht, L; Rosenfeld, S; Zhu, JZ | 1 |
| Dileep, H; Kumar, JSD; Mann, JJ; Mintz, A; Oufkir, HR; Prabhakaran, J; Ramanathan, G; Solingapuram Sai, KK; Whitlow, CT | 1 |
| Carberry, P; Castrillon, J; Dileep Kumar, JS; Mintz, A; Molotkov, A; Prabhakaran, J; Salling, MC | 1 |
| Çetin, İ; Topçul, MR | 1 |
3 trial(s) available for quinazolines and verubulin
| Article | Year |
|---|---|
Phase I clinical trial of MPC-6827 (Azixa), a microtubule destabilizing agent, in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Agents; Contrast Media; Demography; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Neoplasms; Quinazolines; Tubulin Modulators | 2010 |
Phase I trial of verubulin (MPC-6827) plus carboplatin in patients with relapsed glioblastoma multiforme.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cohort Studies; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Quinazolines; Survival Rate; Tissue Distribution | 2012 |
A phase 2 trial of verubulin for recurrent glioblastoma: a prospective study by the Brain Tumor Investigational Consortium (BTIC).
Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Disease-Free Survival; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Quinazolines; Treatment Outcome; Young Adult | 2014 |
7 other study(ies) available for quinazolines and verubulin
| Article | Year |
|---|---|
MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Drug Resistance, Multiple; Humans; In Situ Nick-End Labeling; Membrane Transport Proteins; Mice; Mice, Nude; Quinazolines; Structure-Activity Relationship; Tubulin; Xenograft Model Antitumor Assays | 2007 |
Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Neoplasm Transplantation; Quinazolines; Structure-Activity Relationship; Transplantation, Heterologous | 2009 |
Cardiovascular toxicity profiles of vascular-disrupting agents.
Topics: Angiogenesis Inhibitors; Bibenzyls; Cardiovascular System; Clinical Trials as Topic; Humans; Neoplasms; Neovascularization, Pathologic; Organophosphorus Compounds; Quinazolines; Serine; Xanthones | 2011 |
Effects of the tumor-vasculature-disrupting agent verubulin and two heteroaryl analogues on cancer cells, endothelial cells, and blood vessels.
Topics: Animals; Antineoplastic Agents; Blood Vessels; Cell Count; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Endothelial Cells; HCT116 Cells; HT29 Cells; Humans; MCF-7 Cells; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Neovascularization, Pathologic; Quinazolines; Structure-Activity Relationship | 2014 |
Radiosynthesis and in Vivo Evaluation of [
Topics: Animals; Brain; Carbon Radioisotopes; Ligands; Mice; Microtubules; Positron-Emission Tomography; Quinazolines; Rats | 2018 |
In vivo evaluation of a microtubule PET ligand, [
Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Heart; Ligands; Liver; Mice; Mice, Inbred C57BL; Microtubules; Models, Animal; Positron-Emission Tomography; Quinazolines; Radioactive Tracers | 2022 |
Antitumor Activity of Tubulin-Binding Agent MPC-6827 on Different Types of Cancer Cell Lines.
Topics: Antineoplastic Agents; Apoptosis; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Female; HeLa Cells; Humans; Neoplasms; Quinazolines; Tubulin | 2022 |