Compounds > quinazolines
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quinazolines and u 0126

quinazolines has been researched along with u 0126 in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's28 (50.91)29.6817
2010's26 (47.27)24.3611
2020's1 (1.82)2.80

Authors

AuthorsStudies
Abe, K; Saito, H1
Arteaga, CL; Coffey, RJ; Forbes, JT; Lenferink, AE; Shawver, LK; Simpson, JF1
Bergström, JD; Heldin, NE; Westermark, B1
Arteaga, CL; Forbes, JT; Kurokawa, H; Lenferink, AE; Pisacane, PI; Simpson, JF; Sliwkowski, MX1
Cussac, D; Denis, C; Paris, H; Schaak, S1
Buresi, MC; Buret, AG; Hollenberg, MD; MacNaughton, WK1
Conzen, SD; Coticchia, CM; Dickson, RB; Nishanian, TG; Ramljak, D; Ringel, MD; Saji, M1
Gavard, J; Mège, RM; Monnet, C; Sobel, A1
Chalothorn, D; Faber, JE; Jackson, LF; Lee, DC; Zhang, H1
Kolachana, P; Lawsin, LM; Moore, J; Perlman, A; Ringel, MD; Saji, M1
Civiello, G; Janne, PA; Johnson, BE; Mukohara, T1
Bunting, M; Hanson, BJ; Hanson, GT; O'Grady, M; Raha, D1
Abe, M; Egami, H; Hirota, M; Nozawa, F; Ogawa, M; Tan, X1
Kim, SY; Kim, YK; Kwon, CH; Lee, JS1
Chayama, K; Kuwahara, K; Miyata, H; Sasaki, T; Serikawa, M1
Fukuda, Y; Goto, M; Terakawa, M; Tomimori, Y1
Kanda, Y; Watanabe, Y1
Hake, LE; Keady, BT; Kuo, P; Martínez, SE; Yuan, L1
Daubert, RA; Schnellmann, RG; Yan, Y; Zhuang, S1
Ascoli, M; Shiraishi, K1
Chao, HH; Chen, YL; Cheng, TH; Chiu, WT; Hong, HJ; Lin, JW; Liu, JC; Shyu, KG; Wu, CH1
Furukawa, S; He, Y; Koketsu, M; Nishina, A; Sekiguchi, A1
Chen, DY; Hou, Y; Li, M; Liang, CG; Lin, SL; Schatten, H; Sun, QY; Xiong, B; Xu, BZ1
Cai, L; Du, T; Hertz, L; Li, B; Li, H; Peng, L; Song, D1
Cai, L; Hertz, L; Li, B; Nu, W; Peng, L; Zhang, H; Zhang, S1
Choi, WS; Han, JW; Jeong, KJ; Kang, JK; Kim, YK; Lee, HY; Lee, KB; Park, CG; Park, SY; Seo, JH1
Chen, RS; Cheng, CM; Chuang, SM; Ciou, SC; Jhan, JY; Ko, JC; Lee, WT; Lin, ST; Lin, YW; Su, YJ1
Kawanishi, M; Koizumi, K; Nishimura, M; Saiki, I; Sakurai, H; Shin, MS; Singhirunnusorn, P; Suzuki, S1
Buharalioglu, CK; Malik, KU; Mugabe, BE; Song, CY; Waters, CM; Yaghini, FA1
Feng, R; Hu, Q; Li, L; Li, M; Wang, S; Wen, J; Yang, X; Zhang, L1
Ansaldi, F; Bagnasco, L; Ballestrero, A; Cea, M; Cirmena, G; Garuti, A; Grillo, V; Icardi, G; Moran, E; Nencioni, A; Parodi, S; Patrone, F; Rocco, I; Soncini, D; Zoppoli, G1
Chan, R; Jacks, T; Jasper, PJ; Lane, K; Lauffenburger, DA; Lazzara, MJ; Neel, BG; Sorger, PK; Yaffe, MB1
Balbi, A; Ballestrero, A; Castagnino, N; Montagna, R; Moran, E; Nencioni, A; Parodi, S; Pesenti, R; Soncini, D; Tortolina, L1
Banerjee, R; Belinsky, G; Huang, Y; Jean-Claude, BJ; McNamee, JP; Qiu, Q1
Birtwistle, M; Calder, M; Gilbert, D; Grindlay, J; Kholodenko, B; Kolch, W; Orton, R; Pitt, A; Sturm, OE; Vyshemirsky, V1
Galettis, P; Links, M; Luk, PP1
Biswas, A; Carbajal, L; Hammes, SR; Niswander, LM; Prizant, H1
Chung, WC; Gold, KA; Hittelman, WN; Kang, SM; Ki Hong, W; Kim, ES; Koo, JS; Lee, J; Ryu, SH1
Furukawa, Y; Karakida, S; Kawano, Y; Narahara, H; Sasaki, T; Utsunomiya, Y1
Grandal, MV; Grøvdal, LM; Holst, MR; Kim, J; Knudsen, SL; van Deurs, B1
Li, H; Schmid-Bindert, G; Su, B; Wang, D; Yang, X; Zhao, Y; Zhou, C1
Arao, T; Maegawa, M; Matsumoto, K; Nishio, K1
Ikari, A; Sato, T; Sugatani, J; Watanabe, R; Yamazaki, Y1
Han, J; Kil, WH; Kim, S; Lee, JE; Nam, SJ; Shin, I1
Gong, K; Li, X; Liu, W; Luo, K; Wang, K1
Cebrián-Pérez, JA; Colás, C; Luna, C; Muiño-Blanco, T; Pérez-Pé, R1
Deng, X; Erfani, SF; Hemler, ME; Hoff, J; Jin, H; Kaetzel, DM; Li, Q; Novak, M; Rabinovitz, I; Sharma, C; Sonnenberg, A; Stipp, CS; Yang, H; Yang, XH; Yi, Y; Zhou, P1
Bae, YK; Choi, MS; Hong, KM; Kim, HT; Kim, S; Kim, YN; Kwon, JY; Shim, J; Sung, JY1
Deng, ZL; Dong, YC; Han, QL; Jiang, T; Lv, XH; Ren, H; Xing, WJ; Zou, Y1
Kim, HS; Lee, SY; Shin, SJ1
Bi, LL; Chen, M; Gan, XD; Wang, YG; Wang, ZQ; Zhao, F1
Gao, FH; Guo, YH; Jiang, B; Shi, J; Yuan, HH1
Andric, N; Fa, S; Kaisarevic, S; Kovacevic, R; Odzic, L; Pogrmic-Majkic, K; Samardzija, D1
Chen, B; Chicoine, LG; Jin, Y; Liu, Y; Nelin, LD; White, HA1
Azuma, M; Kim, M; Ko, S; Lee, DA; Lee, SH; Park, H; Parsons, MJ; Prober, D; Shin, D; So, J1

Other Studies

55 other study(ies) available for quinazolines and u 0126

ArticleYear
The mitogen-activated protein kinase cascade mediates neurotrophic effect of epidermal growth factor in cultured rat hippocampal neurons.
    Neuroscience letters, 2000, Mar-17, Volume: 282, Issue:1-2

    Topics: Animals; Blotting, Western; Butadienes; Cell Survival; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hippocampus; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurons; Nitriles; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Quinazolines; Rats; Recombinant Proteins; Signal Transduction; Tyrphostins

2000
Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-15, Volume: 97, Issue:17

    Topics: Animals; Butadienes; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Dimerization; DNA; Down-Regulation; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Nitriles; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Quinazolines; Receptor, ErbB-2; Signal Transduction; Time Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrphostins

2000
Epidermal growth factor receptor signaling activates met in human anaplastic thyroid carcinoma cells.
    Experimental cell research, 2000, Aug-25, Volume: 259, Issue:1

    Topics: Antineoplastic Agents; Butadienes; Carcinoma; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-met; Quinazolines; RNA, Messenger; Suramin; Thyroid Neoplasms; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrphostins

2000
Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells.
    Cancer research, 2000, Oct-15, Volume: 60, Issue:20

    Topics: Animals; Breast Neoplasms; Butadienes; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Gene Expression; Humans; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Tamoxifen; Transcription, Genetic; Tyrphostins; Xenograft Model Antitumor Assays

2000
alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation.
    The Journal of biological chemistry, 2002, May-31, Volume: 277, Issue:22

    Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Arachidonic Acid; Bacterial Proteins; Brimonidine Tartrate; Butadienes; Cell Line; Cell Nucleus; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; MAP Kinase Signaling System; Matrix Metalloproteinases; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Nitriles; Pertussis Toxin; Phosphorylation; Protein Binding; Proteins; Quinacrine; Quinazolines; Quinoxalines; Rats; Receptors, Adrenergic, alpha-2; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Swine; Transcriptional Activation; Tyrphostins; Virulence Factors, Bordetella

2002
Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:12

    Topics: Androstadienes; Butadienes; Cell Line; Chlorides; Epithelial Cells; Humans; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Nitriles; Nitrobenzenes; Phospholipases A; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Pyridines; Pyrimidines; Quinazolines; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Tyrphostins; Wortmannin

2002
Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells.
    Experimental cell research, 2003, Jul-15, Volume: 287, Issue:2

    Topics: Animals; Apoptosis; bcl-X Protein; Butadienes; Cell Line; Chromones; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Quinazolines; Up-Regulation

2003
Clustering of cellular prion protein induces ERK1/2 and stathmin phosphorylation in GT1-7 neuronal cells.
    FEBS letters, 2004, Oct-08, Volume: 576, Issue:1-2

    Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Butadienes; Cells, Cultured; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Mice; Microscopy, Confocal; Microtubule Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Nitriles; Phosphoproteins; Phosphorylation; PrPC Proteins; Quinazolines; RNA, Small Interfering; Stathmin; Tyrphostins

2004
Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
    Circulation research, 2004, Nov-12, Volume: 95, Issue:10

    Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Anthracenes; Aorta, Thoracic; Bacterial Proteins; Benzopyrans; Butadienes; Catheterization; Cell Division; Dipeptides; ErbB Receptors; Flavonoids; Glycine; Hydroxamic Acids; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Organ Culture Techniques; Phenylephrine; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Thrombin; Tyrphostins

2004
Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.
    Annals of clinical and laboratory science, 2004,Summer, Volume: 34, Issue:3

    Topics: Angiotensin II; Animals; Butadienes; Cell Line; Chromones; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Epidermal Growth Factor; Glomerular Mesangium; Immunoblotting; Losartan; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Tyrphostins

2004
Therapeutic targeting of multiple signaling pathways in malignant pleural mesothelioma.
    Oncology, 2005, Volume: 68, Issue:4-6

    Topics: Antibiotics, Antineoplastic; Butadienes; Cell Cycle; Chromones; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; Mesothelioma; Mitogen-Activated Protein Kinase 3; Morpholines; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pleural Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; Signal Transduction; Sirolimus; Transforming Growth Factor alpha; Tumor Cells, Cultured

2005
Combining RNA interference and kinase inhibitors against cell signalling components involved in cancer.
    BMC cancer, 2005, Oct-03, Volume: 5

    Topics: Antibodies, Monoclonal; beta-Lactamases; Butadienes; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Immunohistochemistry; Inhibitory Concentration 50; MAP Kinase Kinase 1; Neoplasms; Nitriles; Oligonucleotides, Antisense; Phosphorylation; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Signal Transduction; Transcription Factor AP-1; Transfection; Tyrphostins

2005
Involvement of MMP-7 in invasion of pancreatic cancer cells through activation of the EGFR mediated MEK-ERK signal transduction pathway.
    Journal of clinical pathology, 2005, Volume: 58, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Blotting, Western; Butadienes; Culture Media, Conditioned; Down-Regulation; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Male; Matrix Metalloproteinase 7; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Neoplasm Invasiveness; Nitriles; Pancreatic Neoplasms; Quinazolines; Signal Transduction; Tight Junctions; Tumor Cells, Cultured; Tyrphostins

2005
EGFR-dependent ERK activation triggers hydrogen peroxide-induced apoptosis in OK renal epithelial cells.
    Archives of toxicology, 2006, Volume: 80, Issue:6

    Topics: Animals; Apoptosis; Butadienes; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hydrogen Peroxide; Kidney Tubules, Proximal; MAP Kinase Kinase 1; Membrane Potentials; Mitochondrial Membranes; Nitriles; Opossums; Oxidants; Pyrimidines; Quinazolines; Transfection; Tyrphostins

2006
The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
    International journal of oncology, 2006, Volume: 28, Issue:4

    Topics: Anthracenes; Bile Duct Neoplasms; Butadienes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Clone Cells; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Quinazolines; Radiation-Sensitizing Agents

2006
Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: Animals; Butadienes; Cell Line, Tumor; Chemokine CXCL2; Chemokines; Chymases; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Gene Expression; Humans; Imidazoles; Interleukin-8; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Neutrophils; Nitriles; Peritonitis; Pertussis Toxin; Pyridines; Quinazolines; RNA, Messenger; Serine Endopeptidases

2006
Nicotine-induced vascular endothelial growth factor release via the EGFR-ERK pathway in rat vascular smooth muscle cells.
    Life sciences, 2007, Mar-20, Volume: 80, Issue:15

    Topics: Animals; Blotting, Western; Butadienes; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Hexamethonium; Muscle, Smooth, Vascular; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nitriles; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tyrphostins; Vascular Endothelial Growth Factor A

2007
MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes.
    Journal of cell science, 2007, Mar-15, Volume: 120, Issue:Pt 6

    Topics: Animals; Aurora Kinases; Bacterial Proteins; Bacterial Toxins; Benzamides; Butadienes; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Female; Guanine Nucleotide Exchange Factors; Meiosis; Mitogen-Activated Protein Kinases; Mutation; Nitriles; Oocytes; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-mos; Quinazolines; rho GTP-Binding Proteins; Xenopus laevis; Xenopus Proteins

2007
Epiregulin promotes proliferation and migration of renal proximal tubular cells.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1

    Topics: Animals; Blotting, Western; Butadienes; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Chromones; Enzyme Inhibitors; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Female; Kidney Tubules, Proximal; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Rabbits; Tyrphostins; Wound Healing

2007
Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.
    Endocrinology, 2007, Volume: 148, Issue:7

    Topics: Animals; Blotting, Western; Butadienes; Cell Proliferation; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP; Dipeptides; Epidermal Growth Factor; Flavonoids; Immunohistochemistry; Inositol Phosphates; Leydig Cells; Luteinizing Hormone; Male; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Pyrazoles; Pyrimidines; Quinazolines; Rats; Recombinant Proteins; Signal Transduction; Steroids; Tyrphostins

2007
Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: Animals; Aorta, Thoracic; Blotting, Northern; Blotting, Western; Butadienes; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Endothelin-1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Leptin; Male; Metalloendopeptidases; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Signal Transduction; Transcriptional Activation; Tyrosine; Tyrphostins

2007
Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase.
    Journal of neuroscience research, 2008, Feb-15, Volume: 86, Issue:3

    Topics: Animals; Antioxidants; Azoles; Butadienes; Carbazoles; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Indole Alkaloids; Isoindoles; Mitogen-Activated Protein Kinases; Neurites; Neurofilament Proteins; Nitriles; Organoselenium Compounds; Oxidation-Reduction; PC12 Cells; Pertussis Toxin; Phosphorylation; Quinazolines; Rats; Receptor Protein-Tyrosine Kinases; Selenium; Tyrphostins

2008
PI3-kinase and mitogen-activated protein kinase in cumulus cells mediate EGF-induced meiotic resumption of porcine oocyte.
    Domestic animal endocrinology, 2008, Volume: 34, Issue:4

    Topics: Animals; Butadienes; Cells, Cultured; Chromones; Cumulus Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Meiosis; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oocytes; Phosphatidylinositol 3-Kinases; Phosphorylation; Quinazolines; Swine; Tyrphostins

2008
Stimulation by vasopressin of ERK phosphorylation and vector-driven water flux in astrocytes is transactivation-dependent.
    European journal of pharmacology, 2008, Jun-10, Volume: 587, Issue:1-3

    Topics: Animals; Astrocytes; Butadienes; Cell Size; Cells, Cultured; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Mice; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Quinazolines; Stimulation, Chemical; Transcriptional Activation; Tyrphostins; Vasopressins; Water

2008
Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.
    Psychopharmacology, 2008, Volume: 201, Issue:3

    Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Astrocytes; Butadienes; Calcium; Cells, Cultured; Chelating Agents; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fluorobenzenes; Fluoxetine; Gene Expression; Indoles; Maleimides; Mice; Nitriles; Phosphorylation; Piperidines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Quinazolines; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Signal Transduction; Substrate Specificity; Transcriptional Activation; Tyrphostins; Up-Regulation; Urea

2008
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
    Experimental & molecular medicine, 2008, Dec-31, Volume: 40, Issue:6

    Topics: Butadienes; Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Cyclooxygenase 2; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lysophospholipids; Nitriles; Ovarian Neoplasms; Pertussis Toxin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrimidines; Quinazolines; Receptors, Lysophosphatidic Acid; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; src-Family Kinases; Transcriptional Activation; Tyrphostins

2008
Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation.
    Experimental cell research, 2009, Sep-10, Volume: 315, Issue:15

    Topics: Animals; Antineoplastic Agents; Apoptosis; Butadienes; Cell Line, Tumor; Emodin; Gefitinib; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Quinazolines; Rad51 Recombinase; RNA, Small Interfering; Signal Transduction

2009
TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling.
    Molecular and cellular biology, 2009, Volume: 29, Issue:20

    Topics: Anthracenes; Butadienes; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Imidazoles; Lactones; MAP Kinase Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Resorcinols; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha

2009
Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and epidermal growth factor receptor transactivation.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Butadienes; Cell Culture Techniques; Cell Migration Assays; Cell Movement; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Sprague-Dawley; src-Family Kinases; Syk Kinase; Transcriptional Activation; Tyrphostins

2010
The EGF receptor-sox2-EGF receptor feedback loop positively regulates the self-renewal of neural precursor cells.
    Stem cells (Dayton, Ohio), 2010, Volume: 28, Issue:2

    Topics: Animals; Blotting, Western; Butadienes; Cell Proliferation; Cells, Cultured; Chromatin Immunoprecipitation; Chromones; Enzyme Inhibitors; ErbB Receptors; Immunohistochemistry; In Vitro Techniques; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Neurons; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; RNA Interference; SOXB1 Transcription Factors; Tyrphostins

2010
Ras-induced resistance to lapatinib is overcome by MEK inhibition.
    Current cancer drug targets, 2010, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Butadienes; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Genes, ras; Humans; Immunoblotting; Lapatinib; Mitogen-Activated Protein Kinase Kinases; Mutation; Nitriles; Quinazolines; Receptor, ErbB-2; Signal Transduction

2010
Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations.
    Cancer research, 2010, May-01, Volume: 70, Issue:9

    Topics: Animals; Antineoplastic Agents; Butadienes; Carcinoma, Non-Small-Cell Lung; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; HeLa Cells; Humans; Lung Neoplasms; Mice; Mutation; Nitriles; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Quinazolines

2010
Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.
    Current cancer drug targets, 2010, Volume: 10, Issue:7

    Topics: Antineoplastic Agents; Breast Neoplasms; Butadienes; Cell Line, Tumor; Computational Biology; Computer Simulation; Female; G1 Phase; Humans; Lapatinib; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Mutant Proteins; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Quinazolines; Receptor, ErbB-2; Receptors, Growth Factor; Resting Phase, Cell Cycle; Signal Transduction

2010
The combi-targeting concept: mechanism of action of the pleiotropic combi-molecule RB24 and discovery of a novel cell signaling-based combination principle.
    Cellular signalling, 2011, Volume: 23, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Butadienes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; DNA Damage; DNA Methylation; Drug Synergism; Enzyme Activation; ErbB Receptors; Gefitinib; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Quinazolines; Signal Transduction; Temozolomide; Triazenes

2011
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier.
    Science signaling, 2010, Dec-21, Volume: 3, Issue:153

    Topics: Animals; Butadienes; Cell Membrane; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Flow Cytometry; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoblotting; Immunoprecipitation; Indoles; Kinetics; MAP Kinase Kinase Kinases; Metabolic Networks and Pathways; Mice; Models, Theoretical; NIH 3T3 Cells; Nitriles; Phosphorylation; Quinazolines; ras Proteins; Signal Transduction

2010
ERK phosphorylation predicts synergism between gemcitabine and the epidermal growth factor receptor inhibitor AG1478.
    Lung cancer (Amsterdam, Netherlands), 2011, Volume: 73, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butadienes; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gemcitabine; Humans; Mutation; Nitriles; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; RNA, Small Interfering; Tyrphostins

2011
GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary.
    Molecular endocrinology (Baltimore, Md.), 2011, Volume: 25, Issue:6

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Butadienes; Cyclic AMP-Dependent Protein Kinases; Doxycycline; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Gonadotropins, Equine; Humans; Luteinizing Hormone; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Nitriles; Ovarian Follicle; Ovary; Progesterone; Quinazolines; Receptor Cross-Talk; Receptors, Corticotropin; Receptors, LH; Signal Transduction; Tyrphostins

2011
Prevention of bronchial hyperplasia by EGFR pathway inhibitors in an organotypic culture model.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:8

    Topics: Bronchi; Butadienes; Cell Line, Tumor; Cyclin D1; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Humans; Hyperplasia; Luciferases; Lung Neoplasms; MAP Kinase Kinase Kinases; Models, Biological; Nitriles; Organ Culture Techniques; Quinazolines; RNA, Small Interfering

2011
Effect of heparin-binding EGF-like growth factor and amphiregulin on the MAP kinase-induced production of vascular endothelial growth factor by human granulosa cells.
    Growth factors (Chur, Switzerland), 2011, Volume: 29, Issue:6

    Topics: Amphiregulin; Blotting, Western; Butadienes; Cell Line; Cell Proliferation; EGF Family of Proteins; Enzyme-Linked Immunosorbent Assay; Female; Glycoproteins; Granulosa Cells; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Nitriles; Quinazolines; Tyrphostins; Vascular Endothelial Growth Factors

2011
EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells.
    Cellular signalling, 2012, Volume: 24, Issue:1

    Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Chromones; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gene Expression; Gene Expression Profiling; Humans; Imidazoles; MAP Kinase Kinase 1; Morpholines; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; RNA, Messenger; Signal Transduction; Tyrphostins; Up-Regulation

2012
Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines.
    Advances in medical sciences, 2011, Volume: 56, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Butadienes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Gefitinib; Humans; Lung Neoplasms; MAP Kinase Kinase Kinases; Morpholines; Mutation; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction

2011
What can and cannot be done using a microarray analysis? Treatment stratification and clinical applications in oncology.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:12

    Topics: Antineoplastic Agents; Butadienes; Early Growth Response Protein 1; ErbB Receptors; Gene Expression Profiling; Genes, Neoplasm; HEK293 Cells; Humans; Microarray Analysis; Molecular Targeted Therapy; Mutation; Neoplasms; Nitriles; Protein Kinase Inhibitors; Quinazolines; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; Tyrphostins

2011
Increase in claudin-2 expression by an EGFR/MEK/ERK/c-Fos pathway in lung adenocarcinoma A549 cells.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Binding Sites; Butadienes; Cell Line, Tumor; Claudins; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; MAP Kinase Signaling System; Nitriles; Promoter Regions, Genetic; Protease Inhibitors; Protein Binding; Proto-Oncogene Proteins c-fos; Quinazolines; RNA, Messenger; RNA, Small Interfering; Transcription Factor AP-1; Tyrphostins

2012
A functional comparison between the HER2(high)/HER3 and the HER2(low)/HER3 dimers on heregulin-β1-induced MMP-1 and MMP-9 expression in breast cancer cells.
    Experimental & molecular medicine, 2012, Aug-31, Volume: 44, Issue:8

    Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lapatinib; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; MCF-7 Cells; Neuregulin-1; Nitriles; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Protein Multimerization; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3

2012
Epidermal growth factor enhances MPC-83 pancreatic cancer cell migration through the upregulation of aquaporin 3.
    Molecular medicine reports, 2012, Volume: 6, Issue:3

    Topics: Antineoplastic Agents; Aquaporin 3; Butadienes; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Nitriles; Pancreatic Neoplasms; Phosphorylation; Quinazolines; Up-Regulation

2012
A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep.
    Biology of reproduction, 2012, Volume: 87, Issue:4

    Topics: Animals; Butadienes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Quinazolines; Sheep; Sperm Capacitation; Spermatozoa; Tissue Distribution; Tyrphostins

2012
Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis.
    Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:8

    Topics: Animals; Butadienes; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Female; Focal Adhesion Kinase 1; Humans; Integrin alpha6beta4; Lapatinib; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Metastasis; Nitriles; Phosphorylation; Quinazolines; Receptor, ErbB-2; Tetraspanin 24; Transendothelial and Transepithelial Migration

2012
An in vivo C. elegans model system for screening EGFR-inhibiting anti-cancer drugs.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents; Butadienes; Caenorhabditis elegans; Drug Screening Assays, Antitumor; Enzyme Inhibitors; ErbB Receptors; Humans; Models, Animal; Mutation; Neoplasms; Nitriles; Phenotype; Protein Structure, Tertiary; Quinazolines; Transgenes; Tyrphostins

2012
Effects of epidermal growth factor receptor and phosphatase and tensin homologue gene expression on the inhibition of U87MG glioblastoma cell proliferation induced by protein kinase inhibitors.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:1

    Topics: Butadienes; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Furans; Gene Expression; Glioblastoma; Humans; Nitriles; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Pyrimidines; Quinazolines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2013
ERK1/2 activation mediated by the nutlin‑3‑induced mitochondrial translocation of p53.
    International journal of oncology, 2013, Volume: 42, Issue:3

    Topics: Antioxidants; Apoptosis; Benzothiazoles; Butadienes; Cell Line, Tumor; Cyclic N-Oxides; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Osteosarcoma; Phosphorylation; Piperazines; Protein Transport; Quinazolines; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Toluene; Tumor Suppressor Protein p53; Tyrphostins

2013
Time-dependent regulation of neuregulin-1β/ErbB/ERK pathways in cardiac differentiation of mouse embryonic stem cells.
    Molecular and cellular biochemistry, 2013, Volume: 380, Issue:1-2

    Topics: Actins; Animals; Atrial Natriuretic Factor; Butadienes; Cell Differentiation; Cell Line; Embryoid Bodies; Embryonic Stem Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; GATA4 Transcription Factor; Gene Expression Regulation, Developmental; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice; Myocytes, Cardiac; Myosin Light Chains; Neuregulin-1; Nitriles; Phosphorylation; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; T-Box Domain Proteins; Time Factors; Transcription Factors; Tyrphostins

2013
[EGFR-ERK signaling pathway down-regulates miRNA-145 in lung cancer cells].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:3

    Topics: Butadienes; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Quinazolines; Tyrphostins

2013
Hexabromocyclododecane facilitates FSH activation of ERK1/2 and AKT through epidermal growth factor receptor in rat granulosa cells.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: Animals; Butadienes; Cells, Cultured; ErbB Receptors; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Granulosa Cells; Hydrocarbons, Brominated; MAP Kinase Signaling System; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Wistar; Receptors, LH; Toxicity Tests; Tyrphostins

2014
Hypoxic proliferation requires EGFR-mediated ERK activation in human pulmonary microvascular endothelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2017, 05-01, Volume: 312, Issue:5

    Topics: Arginase; Butadienes; Cell Count; Cell Hypoxia; Cell Proliferation; Cell Survival; Culture Media, Conditioned; Endothelial Cells; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gene Knockdown Techniques; Gene Silencing; Humans; Lung; Microvessels; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Quinazolines; RNA, Small Interfering; Tyrphostins

2017
Attenuating the Epidermal Growth Factor Receptor-Extracellular Signal-Regulated Kinase-Sex-Determining Region Y-Box 9 Axis Promotes Liver Progenitor Cell-Mediated Liver Regeneration in Zebrafish.
    Hepatology (Baltimore, Md.), 2021, Volume: 73, Issue:4

    Topics: Animals; Animals, Genetically Modified; Butadienes; Cell Differentiation; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Liver Regeneration; MAP Kinase Signaling System; Nitriles; Quinazolines; SOX9 Transcription Factor; Stem Cells; Tyrphostins; Zebrafish

2021