Page last updated: 2024-08-21

quinazolines and trimethoprim

quinazolines has been researched along with trimethoprim in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199015 (83.33)18.7374
1990's2 (11.11)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crippen, GM; Ghose, AK1
Hynes, JB; McCullough, JL; Weinstein, GD1
Allegra, CJ; Beaver, J; Boarman, D; Chabner, B; Kovacs, JA; Lewis, M; Masur, H; Parrillo, JE1
Chastang, C; Derouin, F1
Montgomery, AB1
McCormack, JJ; Tong, WP; Webster, LK1
Allegra, CJ; Chabner, BA; Drake, J; Kovacs, JA; Lunde, M; Masur, H; Parrillo, JE; Swan, JC1
Kovacs, JA; Masur, H1
Allegra, CJ; Chabner, B; Drake, J; Kennedy, S; Kovacs, JA; Masur, H; Parrillo, JE; Swan, JC1
Fischl, MA1
Jaffe, JJ; McCormack, JJ; Meymarian, E1
Burchall, JJ1
Heydorn, AO; Voigt, WP1
Baccanari, DP; Boytos, CM; Chan, JH; Hong, JS; Joyner, SS; Kuyper, LF; Rudolph, SK; Tansik, RL1
Bagnara, AS; Nott, SE1
Hoff, JS; Kristich, CJ1

Reviews

3 review(s) available for quinazolines and trimethoprim

ArticleYear
Recent developments in the therapy and management of Pneumocystis carinii pneumonia in patients with AIDS.
    AIDS clinical review, 1989

    Topics: Acquired Immunodeficiency Syndrome; Dapsone; Drug Therapy, Combination; Humans; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1989
Pneumocystis carinii pneumonia: therapy and prophylaxis.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Pentamidine; Pneumonia, Pneumocystis; Pyrimethamine; Quinazolines; Recurrence; Sulfadiazine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1988
Treatment and prophylaxis of Pneumocystis carinii pneumonia.
    AIDS (London, England), 1988, Volume: 2 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Antiprotozoal Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Humans; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate; Zidovudine

1988

Trials

1 trial(s) available for quinazolines and trimethoprim

ArticleYear
Treatment and prophylaxis of Pneumocystis carinii pneumonia.
    AIDS (London, England), 1988, Volume: 2 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Antiprotozoal Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Humans; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate; Zidovudine

1988

Other Studies

15 other study(ies) available for quinazolines and trimethoprim

ArticleYear
General distance geometry three-dimensional receptor model for diverse dihydrofolate reductase inhibitors.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:7

    Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography; Folic Acid Antagonists; Liver; Models, Chemical; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Rats; Structure-Activity Relationship; Triazines

1984
Cost of prescription drugs.
    The Medical letter on drugs and therapeutics, 1975, Jan-17, Volume: 17, Issue:2

    Topics: Chlordiazepoxide; Diphenhydramine; Diuretics; Fees, Pharmaceutical; Health Expenditures; Humans; Prescription Fees; Quinazolines; Sulfamethoxazole; Tetracycline; Trimethoprim; United States

1975
In vitro screening of biochemical activity of folic acid antagonists in skin.
    The Journal of investigative dermatology, 1977, Volume: 68, Issue:6

    Topics: Animals; Animals, Newborn; Chlorobenzenes; Depression, Chemical; DNA; Folic Acid Antagonists; Methotrexate; Psoriasis; Pyrimethamine; Pyrimidines; Quinazolines; Rats; Skin; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim

1977
Characterization of de novo folate synthesis in Pneumocystis carinii and Toxoplasma gondii: potential for screening therapeutic agents.
    The Journal of infectious diseases, 1989, Volume: 160, Issue:2

    Topics: 4-Aminobenzoic Acid; Animals; Drug Combinations; Drug Evaluation, Preclinical; Folic Acid; Pneumocystis; Quinazolines; Rats; Sulfamethoxazole; Toxoplasma; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1989
In vitro effects of folate inhibitors on Toxoplasma gondii.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:10

    Topics: Animals; Enzyme-Linked Immunosorbent Assay; Folic Acid Antagonists; Microbial Sensitivity Tests; Pyrimethamine; Pyrimidines; Quinazolines; Sulfamethoxazole; Sulfisoxazole; Toxoplasma; Trimethoprim; Trimetrexate

1989
Effect of trimethoprim, paracetamol and cimetidine on trimetrexate metabolism by rat perfused isolated livers.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:11

    Topics: Acetaminophen; Animals; Cimetidine; Drug Interactions; Folic Acid Antagonists; In Vitro Techniques; Liver; Male; Quinazolines; Rats; Rats, Inbred Strains; Trimethoprim; Trimetrexate

1987
Potent effect of trimetrexate, a lipid-soluble antifolate, on Toxoplasma gondii.
    The Journal of infectious diseases, 1987, Volume: 155, Issue:5

    Topics: Animals; Cells, Cultured; Drug Therapy, Combination; Folic Acid Antagonists; Macrophages; Mice; Mice, Inbred BALB C; Pentamidine; Pyrimethamine; Quinazolines; Sulfadiazine; Toxoplasma; Toxoplasmosis, Animal; Trimethoprim; Trimetrexate

1987
Treatment of Pneumocystis carinii pneumonia.
    The Medical letter on drugs and therapeutics, 1987, Nov-20, Volume: 29, Issue:753

    Topics: Acquired Immunodeficiency Syndrome; Dapsone; Drug Combinations; Folic Acid Antagonists; Humans; Methylprednisolone; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Recurrence; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1987
Efficacy of trimetrexate, a potent lipid-soluble antifolate, in the treatment of rodent Pneumocystis carinii pneumonia.
    The American journal of tropical medicine and hygiene, 1988, Volume: 39, Issue:5

    Topics: Administration, Oral; Animals; Drug Therapy, Combination; Folic Acid Antagonists; Injections, Subcutaneous; Male; Pneumonia, Pneumocystis; Quinazolines; Rats; Rats, Inbred Strains; Sulfamethoxazole; Trimethoprim; Trimetrexate

1988
Comparative properties of schistosomal and filarial dihydrofolate reductases.
    Biochemical pharmacology, 1972, Mar-01, Volume: 21, Issue:5

    Topics: Anthelmintics; Chromatography, Gel; Eukaryota; Filarioidea; Folic Acid Antagonists; Molecular Weight; NADP; Pyrimethamine; Quinazolines; Schistosoma mansoni; Structure-Activity Relationship; Suramin; Tetrahydrofolate Dehydrogenase; Trimethoprim

1972
Comparative biochemistry of dihydrofolate reductase.
    Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186

    Topics: Animals; Anura; Biochemical Phenomena; Biochemistry; Escherichia coli; Fishes; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Malaria; Methotrexate; Nephropidae; Proteus vulgaris; Pyridines; Pyrimidines; Quinazolines; Rana pipiens; Rats; Staphylococcus; Taenia; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim; Turtles

1971
Chemotherapy of Sarcosporidiosis and theileriosis in domestic animals.
    Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious..., 1981, Volume: 250, Issue:1-2

    Topics: Animals; Cattle; Coccidiostats; Drug Combinations; Goats; Oxytetracycline; Piperidines; Quinazolines; Quinazolinones; Sarcocystosis; Sheep; Sheep Diseases; Sulfadoxine; Theileriasis; Trimethoprim

1981
Selective inhibitors of Candida albicans dihydrofolate reductase: activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines.
    Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

    Topics: Animals; Antifungal Agents; Candida albicans; Drug Design; Folic Acid Antagonists; Humans; Mice; Pyrimethamine; Pyrimidines; Quinazolines; Recombinant Proteins; Structure-Activity Relationship; Trimethoprim; Trimetrexate

1995
The toxicity of antifolates in Babesia bovis.
    International journal for parasitology, 1993, Volume: 23, Issue:3

    Topics: Animals; Babesia bovis; Folic Acid; Folic Acid Antagonists; Pyrimethamine; Pyrimidines; Quinazolines; Trimethoprim; Trimetrexate

1993
Thymidylate Limitation Potentiates Cephalosporin Activity toward Enterococci via an Exopolysaccharide-Based Mechanism.
    ACS chemical biology, 2016, 06-17, Volume: 11, Issue:6

    Topics: Anti-Bacterial Agents; Cell Wall; Cephalosporins; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Drug Synergism; Enterococcus faecalis; Enterococcus faecium; Fluorouracil; Folic Acid Antagonists; Glucose; Polysaccharides; Quinazolines; Tetrahydrofolate Dehydrogenase; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides; Trimethoprim

2016