Page last updated: 2024-08-21

quinazolines and threonine

quinazolines has been researched along with threonine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's0 (0.00)18.2507
2000's7 (46.67)29.6817
2010's7 (46.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ebata, M; Miyazaki, K; Otsuka, H1
Diao, C; Hollenberg, MD; Matsubara, S; Wong, NC; Zheng, XL1
Blencke, S; Daub, H; Ullrich, A1
Bernd, A; Guschel, M; Kaufmann, R; Kippenberger, S; Knies, Y; Loitsch, S; Müller, J1
Reddy, GK1
Gadea, BB; Ruderman, JV1
Aoe, K; Aoe, M; Asano, H; Date, H; Ichihara, S; Inukai, M; Ito, S; Kiura, K; Ouchida, M; Shimizu, N; Soh, J; Suehisa, H; Toyooka, S1
Kawanishi, M; Koizumi, K; Nishimura, M; Saiki, I; Sakurai, H; Shin, MS; Singhirunnusorn, P; Suzuki, S1
Arellano-Plancarte, A; Catt, KJ; Hernandez-Aranda, J; Olivares-Reyes, JA1
Danko, J; Horton, K; Kostyal, D; Lanning, C; Shay, T; Welt, RS; Welt, S1
Alexander, PB; McKnight, SL; Wang, J1
Chang, S; Ding, J; Ding, K; Geng, M; Liu, Y; Lu, X; Luo, J; Pei, D; Ren, X; Tu, Z; Xu, S; Xu, T; Xu, Y; Zhang, L; Zhang, Z1
Han, JY; Hwang, JA; Kim, HT; Kim, JH; Kim, SH; Lee, GK; Lee, JS; Lee, Y; Lee, YS; Nam, BH; Yun, T; Zhang, W1
Dai, B; Fang, B; Gao, W; Gold, KA; Heymach, JV; Hofstetter, WL; Lu, H; Minna, J; Ou, Z; Roth, JA; Swisher, SG; Wang, L; Wang, M; Wu, S; Zhang, L1
Ali, SM; Busaidy, NL; Chmielecki, J; Elvin, JA; Erlich, RL; Heilmann, AM; Khan, SA; Lipson, D; Miller, VA; Murthy, R; Nangia, C; Ross, JS; Shah, MH; Sherman, SI; Stephens, PJ; Subbiah, I; Subbiah, V; Sun, JX; Vergilio, JA; Wang, K; Yelensky, R1

Reviews

1 review(s) available for quinazolines and threonine

ArticleYear
Role of epidermal growth factor receptor mutations in predicting sensitivity or resistance to targeted agents in non-small-cell lung cancer.
    Clinical lung cancer, 2005, Volume: 6, Issue:6

    Topics: Amino Acid Substitution; Antineoplastic Agents; Asian People; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Quinazolines; Sex Factors; Threonine

2005

Other Studies

14 other study(ies) available for quinazolines and threonine

ArticleYear
Studi on siomycin. II. The composition and degradation products of siomycin A.
    The Journal of antibiotics, 1969, Volume: 22, Issue:9

    Topics: Acetaldehyde; Alanine; Amino Acids; Anti-Bacterial Agents; Butyrates; Carbon; Chemical Phenomena; Chemistry; Cysteine; Optical Rotatory Dispersion; Oxidation-Reduction; Propionates; Pyruvates; Quinazolines; Thiazoles; Threonine; Valine

1969
Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: Amino Acid Sequence; Apolipoprotein A-I; Binding Sites; Blotting, Western; Chloramphenicol O-Acetyltransferase; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genes, Dominant; Genes, ras; Genes, Reporter; Humans; Insulin; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Protein Synthesis Inhibitors; Quinazolines; ras Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sp1 Transcription Factor; Threonine; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation

2001
Mutation of threonine 766 in the epidermal growth factor receptor reveals a hotspot for resistance formation against selective tyrosine kinase inhibitors.
    The Journal of biological chemistry, 2003, Apr-25, Volume: 278, Issue:17

    Topics: Animals; Antineoplastic Agents; Benzamides; Cell Line; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Humans; Imatinib Mesylate; MAP Kinase Signaling System; Piperazines; Point Mutation; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Threonine; Transfection

2003
Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor.
    The Journal of biological chemistry, 2005, Jan-28, Volume: 280, Issue:4

    Topics: Androstadienes; Apoptosis; Caspase 3; Caspase 8; Caspases; Cell Line; Cell Membrane; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermis; Epithelial Cells; ErbB Receptors; Genes, Dominant; Humans; Immunoblotting; Microscopy, Confocal; Morpholines; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, Angiotensin, Type 1; Signal Transduction; Threonine; Time Factors; Tyrphostins; Wortmannin

2005
Aurora B is required for mitotic chromatin-induced phosphorylation of Op18/Stathmin.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Mar-21, Volume: 103, Issue:12

    Topics: Animals; Aurora Kinase B; Aurora Kinases; Benzamides; Centromere; Chromatin; Chromosomes; Enzyme Inhibitors; Kinesins; Microtubules; Mitosis; Phosphorylation; Protein Serine-Threonine Kinases; Quinazolines; Spindle Apparatus; Stathmin; Threonine; Xenopus; Xenopus Proteins

2006
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.
    Cancer research, 2006, Aug-15, Volume: 66, Issue:16

    Topics: Amino Acid Substitution; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Threonine

2006
TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling.
    Molecular and cellular biology, 2009, Volume: 29, Issue:20

    Topics: Anthracenes; Butadienes; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Imidazoles; Lactones; MAP Kinase Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Resorcinols; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha

2009
Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.
    Biochemical pharmacology, 2010, Mar-01, Volume: 79, Issue:5

    Topics: Angiotensin II; Animals; Cell Line; Enzyme Inhibitors; ErbB Receptors; Hepatocytes; Insulin; Insulin Resistance; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Receptor, Insulin; Serine; Signal Transduction; Threonine; Transcriptional Activation; Tyrphostins; Vasoconstrictor Agents

2010
Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:3

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Female; Humans; Lapatinib; Phosphorylation; Quinazolines; Receptor, ErbB-2; Signal Transduction; Threonine; Trastuzumab; Tyrosine

2012
Targeted killing of a mammalian cell based upon its specialized metabolic state.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Sep-20, Volume: 108, Issue:38

    Topics: 3T3 Cells; Acetyl Coenzyme A; Alcohol Oxidoreductases; Aminoimidazole Carboxamide; Animals; Autophagy; Biocatalysis; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Embryoid Bodies; Embryonic Stem Cells; HeLa Cells; Humans; Mice; Microscopy, Electron, Transmission; Molecular Structure; Quinazolines; Ribonucleotides; Threonine

2011
Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine⁷⁹⁰ → methionine⁷⁹⁰ mutant.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Lung Neoplasms; Methionine; Mice; Mice, Nude; Mice, SCID; Molecular Conformation; Mutation; Neoplasm Transplantation; Pyrimidines; Quinazolines; Structure-Activity Relationship; Threonine; Transplantation, Heterologous

2012
Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations.
    Cancer, 2014, Jul-15, Volume: 120, Issue:14

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asian People; Disease-Free Survival; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation; Neoplasm Staging; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Republic of Korea; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Treatment Outcome; Tumor Cells, Cultured

2014
Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:9

    Topics: Adenine; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Methionine; Mice; Mutation; Piperidines; Pyrazoles; Pyrimidines; Quinazolines; Threonine

2014
Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.
    Oncology, 2016, Volume: 90, Issue:6

    Topics: Aged; Anilides; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Drug Resistance, Neoplasm; Everolimus; Female; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Gene Amplification; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Methionine; Middle Aged; Molecular Targeted Therapy; Mutation; Piperidines; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Pyridines; Quinazolines; Threonine; Thyroid Neoplasms

2016