quinazolines has been researched along with theophylline in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (36.36) | 18.7374 |
| 1990's | 11 (25.00) | 18.2507 |
| 2000's | 12 (27.27) | 29.6817 |
| 2010's | 5 (11.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gogerty, JH; Hardtmann, GE; Iorio, LC; Koletar, G; Pfister, OR | 1 |
| Holtzman, SG; Mumford, GK | 1 |
| Brown, GL; Douglas, FL; Kotake, AN; Mustafa, SJ; Sabouni, MH | 1 |
| Combs, DW; Kirchner, T; Klaubert, DH; Meeks, AS; Rampulla, MS; Rampulla, RA; Ritchie, D; Russell, RK | 1 |
| Befus, AD; Bienenstock, J; Lee, TD; Shanahan, F | 1 |
| Hashimoto, H; Ishii, K; Satoh, K; Taira, N | 1 |
| Gillespie, E | 1 |
| Chiba, S; Haruta, K; Homma, N; Horiuchi, A; Iwatsuki, K; Yonekura, H | 1 |
| Abels, BC; Branch, KR; Branch, RA; Callis, JT; Jackson, EK; Kuan, CJ; Sabra, R | 1 |
| Decker, N; Grima, M; Schwartz, J | 1 |
| Fujimura, H; Tsurumi, K; Yasuda, K | 1 |
| Hamrick, ME; Millen, J; Riley, TN; Waters, IW | 1 |
| Amer, MS; Browder, HP | 1 |
| Parratt, JR; Winslow, E | 1 |
| Burke, G; Chang, LL; Szabo, M | 1 |
| Nott, MW; Winslow, E | 1 |
| Lier, G | 1 |
| Aviado, DM; Folle, LE; Pisanty, J | 1 |
| Göres, E; Grupe, R; Hagen, V; Pietzsch, W | 1 |
| Cazin, L; Mei, YA; Vaudry, H | 1 |
| Jarvis, JE; Reeves, JJ; Sheehan, MJ; Strong, P | 1 |
| Kroll, K; Schrader, J | 1 |
| Holtzman, SG | 1 |
| Jones, CA; Reeves, JJ; Sheehan, MJ; Vardey, CJ; Whelan, CJ | 1 |
| Jourquin, G; Kauffmann, JM | 1 |
| Fredholm, BB; Johansson, B; Kuzmin, A; Zvartau, EE | 1 |
| Fredholm, BB; Lindström, K | 1 |
| Dal Piaz, V; Giovannoni, MP | 1 |
| Chen, Y; Hertz, L; Rathbone, MP | 1 |
| Hamann, M; Richter, A | 1 |
| Chen, CF; Chen, TL; Guengerich, FP; Jan, WC; Lin, LC; Ueng, YF | 1 |
| Anderson, KE; Daniele, N; Foukas, LC; Jensen, J; Ktori, C; Shepherd, PR | 1 |
| Karasawa, A; Katagiri, C; Kusaka, H; Mizutani, M; Nan-ya, K; Nishikawa, S; Noji, T; Sano, J | 1 |
| Chen, RM; Chen, TL; Don, MJ; Tsai, TH; Ueng, YF | 1 |
| Baba, K; Fujiwara, H; Kariya, T; Kawai, T; Minatoguchi, S; Takahashi, M; Takemura, G; Uno, Y; Zhang, C | 1 |
| Holý, A; Kmonícková, E; Potmesil, P; Zídek, Z | 1 |
| Gao, C; Gao, N; Hu, HZ; Liu, S; Wood, JD; Xia, Y | 1 |
| Battastini, AM; Bavaresco, L; Bernardi, A; Delgado-Cañedo, A; Jacques-Silva, MC; Lenz, G; Wink, MR | 1 |
| Fassihi, R; Liu, Q | 1 |
| Adcock, IM; Barnes, PJ; Elliott, WM; Failla, M; Hogg, JC; Ito, K; Ito, M; Kizawa, Y; Kusama, T; To, Y | 1 |
| Kumar, PV; Selvam, TP | 1 |
| Bista, SR; Jahng, Y; Jeong, TC; Kang, MJ; Kang, W; Kim, E; Lee, SK; Noh, K; Seo, YM | 1 |
| Ballanyi, K; Ciechanski, P; Mosca, EV; Roy, A; Scheibli, EC; Wilson, RJ | 1 |
| Chen, Z; Zhang, B | 1 |
1 review(s) available for quinazolines and theophylline
| Article | Year |
|---|---|
Phosphodiesterase 4 inhibitors, structurally unrelated to rolipram, as promising agents for the treatment of asthma and other pathologies.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arthritis, Rheumatoid; Asthma; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Isoenzymes; Lung Diseases, Obstructive; Molecular Structure; Phosphodiesterase Inhibitors; Quinazolines; Rolipram; Theophylline; Xanthines | 2000 |
43 other study(ies) available for quinazolines and theophylline
| Article | Year |
|---|---|
Synthesis and biological evaluation of some 10-substituted 2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-ones, a new class of bronchodilators.
Topics: Animals; Bronchodilator Agents; Dogs; Female; Guinea Pigs; Hemodynamics; Histamine; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Isoproterenol; Lethal Dose 50; Male; Mice; Muscle Contraction; Muscle, Smooth; Ovalbumin; Passive Cutaneous Anaphylaxis; Quinazolines; Structure-Activity Relationship; Theophylline; Trachea | 1975 |
Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for electrical brain stimulation in the rat?
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Carbolines; Chlordiazepoxide; Electric Stimulation; Hypothalamic Area, Lateral; Male; Midazolam; Phenylisopropyladenosine; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reinforcement, Psychology; Self Stimulation; Sensory Thresholds; Theophylline; Triazoles | 1991 |
Effects of CGS-15943A on the relaxations produced by adenosine analogs in human blood vessels.
Topics: Adenosine; Adult; Coronary Vessels; Humans; In Vitro Techniques; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Quinazolines; Saphenous Vein; Theophylline; Triazoles | 1990 |
Design, synthesis and bronchodilatory activity of a series of quinazoline-3-oxides.
Topics: Animals; Bronchial Spasm; Bronchodilator Agents; Dogs; Drug Design; Female; Guinea Pigs; Hemodynamics; Leukotrienes; Magnetic Resonance Spectroscopy; Male; Ovalbumin; Pilocarpine; Quinazolines; Theophylline | 1990 |
Mast cell heterogeneity: effect of anti-allergic compounds on neuropeptide-induced histamine release.
Topics: Animals; Cromolyn Sodium; Dose-Response Relationship, Drug; Histamine Release; Hypersensitivity; Intestinal Mucosa; Male; Mast Cells; Nerve Tissue Proteins; Peritoneal Cavity; Quinazolines; Rats; Rats, Inbred Strains; Theophylline; Thioxanthenes; Xanthones | 1986 |
Comparison of vasodilator effects of DN-9693, a selective inhibitor of cyclic AMP phosphodiesterase, and isobutylmethylxanthine, a non-selective one, in dogs.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antineoplastic Agents; Coronary Circulation; Dogs; Female; Femur; Male; Myocardium; Oxygen Consumption; Quinazolines; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Theophylline; Vasodilator Agents | 1987 |
Anagrelide: a potent and selective inhibitor of platelet cyclic AMP phosphodiesterase enzyme activity.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Blood Platelets; Dose-Response Relationship, Drug; Humans; Milrinone; Platelet Aggregation Inhibitors; Pyridones; Quinazolines; Theophylline | 1988 |
Effects of DN-9693, a synthesized phosphodiesterase inhibitor, on pancreatic exocrine secretion in dogs.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Atropine; Cholecystokinin; Cimetidine; Dogs; Dose-Response Relationship, Drug; Female; Male; Pancreas; Pancreatic Juice; Papaverine; Phentolamine; Phosphodiesterase Inhibitors; Propranolol; Quinazolines; Secretin; Sulpiride; Theophylline | 1989 |
Inhibition of renal vasoconstriction induced by intrarenal hypertonic saline by the nonxanthine adenosine antagonist CGS 15943A.
Topics: Adenosine; Animals; Dogs; Quinazolines; Receptors, Purinergic; Renal Circulation; Saline Solution, Hypertonic; Sodium Chloride; Theophylline; Triazoles; Vasoconstriction | 1989 |
Effect of some new cardiotonic agents on synaptosomal sodium uptake.
Topics: Animals; Cardiotonic Agents; Guinea Pigs; Heart Atria; Imidazoles; Male; Milrinone; Protoveratrines; Pyridones; Quinazolines; Rats; Rats, Inbred Strains; Sodium; Synaptosomes; Tetrodotoxin; Theophylline; Time Factors | 1986 |
Study of drug interaction between the new antiallergic drug 11-oxo-11H-pyrido[2,1-b]quinazoline-2-carboxylic acid and theophylline.
Topics: Aminophylline; Animals; Drug Interactions; Hypersensitivity; Male; Quinazolines; Rats; Rats, Inbred Strains; Theophylline | 1986 |
2-(beta-Arylethylamino)- and 4-(beta-arylethylamino)quinazolines as phosphodiesterase inhibitors.
Topics: Animals; Cattle; Ethylamines; Female; Guinea Pigs; Muscle Relaxation; Muscle, Smooth; Myocardium; Phosphodiesterase Inhibitors; Quinazolines; Theophylline | 1985 |
Effect of quazodine on phosphodiesterase.
Topics: Animals; Brain; Bronchodilator Agents; Cardiovascular System; Cattle; Chemical Phenomena; Chemistry; Male; Phosphoric Monoester Hydrolases; Quinazolines; Rabbits; Theophylline; Vasodilator Agents | 1971 |
Actions of quazodine (MJ1988) on smooth muscle.
Topics: Animals; Aorta; Cats; Depression, Chemical; Duodenum; Electric Stimulation; Female; Guinea Pigs; Ileum; Imidazoles; Male; Muscle Contraction; Muscle, Smooth; Phosphoric Monoester Hydrolases; Portal Vein; Quinazolines; Rabbits; Rats; Receptors, Adrenergic; Theophylline; Trachea; Uterus; Vas Deferens | 1971 |
Thyrotropin and cyclic nucleotide effects on prostaglandin levels in isolated thyroid cells.
Topics: Animals; Cattle; Cyclic AMP; Drug Synergism; In Vitro Techniques; Methyl Ethers; Phosphodiesterase Inhibitors; Prostaglandins; Quinazolines; Radioimmunoassay; Theophylline; Thyroid Gland; Thyrotropin | 1973 |
Effects of quazodine (MJ 1988) on contractions of the isolated hemidiaphragm of the rat and the biventer cervicis muscle of the chick.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Chickens; Diaphragm; Drug Synergism; Electric Stimulation; In Vitro Techniques; Methyl Ethers; Muscle Contraction; Muscles; Quinazolines; Rats; Theophylline; Tubocurarine | 1973 |
[Therapy of arterial blood circulatory disorders associated with predominantly autonomic vascular syndrome].
Topics: Adult; Dysautonomia, Familial; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Male; Muscles; Psychophysiologic Disorders; Pyridines; Quinazolines; Theophylline; Vascular Diseases; Vascular Headaches; Vasodilator Agents | 1968 |
The cardiopulmonary effects of a quinazoline (MJ 1988): cardiac stimulant, pulmonary vasodilator and bronchodilator.
Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Bronchi; Dogs; Heart; Muscle Contraction; Pulmonary Circulation; Quinazolines; Theophylline | 1967 |
[The antianaphylactic effect of derivatives of 4-oxoquinazoline, 4-oxoquinazol-3-yl-benzoic acid and 4-oxoquinazol-3-yl-acetic acid in the rat].
Topics: Anaphylaxis; Animals; Bordetella pertussis; Chemical Phenomena; Chemistry; Kinetics; Passive Cutaneous Anaphylaxis; Quinazolines; Rats; Rats, Inbred Strains; Theophylline | 1984 |
Inhibitory effect of adenosine on electrical activity of frog melanotrophs mediated through A1 purinergic receptors.
Topics: Action Potentials; Adenosine; alpha-MSH; Animals; Cells, Cultured; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Membrane Potentials; Patch-Clamp Techniques; Pertussis Toxin; Phenylisopropyladenosine; Pituitary Gland; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinazolines; Rana ridibunda; Tachyphylaxis; Theophylline; Triazoles; Virulence Factors, Bordetella | 1994 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines | 1995 |
Myocardial adenosine stimulates release of cyclic adenosine monophosphate from capillary endothelial cells in guinea pig heart.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Alprostadil; Animals; Capillaries; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Guinea Pigs; Myocardium; Oxygen; Procaterol; Quinazolines; Theophylline; Triazoles; Vasodilation | 1993 |
Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, in monkeys: comparison to methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Male; Purinergic P1 Receptor Antagonists; Quinazolines; Saimiri; Theophylline; Triazoles; Xanthines | 1996 |
Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo.
Topics: Adenosine; Administration, Cutaneous; Animals; Blood Proteins; Cell Degranulation; Cyproheptadine; Dinitrophenols; Female; Humans; In Vitro Techniques; Injections, Intravenous; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Pleura; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Serotonin Antagonists; Serum Albumin; Skin; Theophylline; Triazoles; Xanthines | 1997 |
Fluorimetric determination of theophylline in serum by inhibition of bovine alkaline phosphatase in AOT based water/in oil microemulsion.
Topics: Alkaline Phosphatase; Animals; Cattle; Chromatography, High Pressure Liquid; Emulsions; Fluorescent Dyes; Fluorometry; Humans; Magnesium; Microchemistry; Models, Chemical; Organophosphorus Compounds; Quinazolines; Quinazolinones; Spectrophotometry, Ultraviolet; Theophylline; Zinc | 1998 |
Caffeine, acting on adenosine A(1) receptors, prevents the extinction of cocaine-seeking behavior in mice.
Topics: Animals; Behavior, Animal; Caffeine; Cocaine; Extinction, Psychological; Male; Mice; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Reward; Substance Abuse, Intravenous; Theophylline; Triazoles; Xanthines | 1999 |
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.
Topics: Adenosine; Animals; Autoradiography; Binding, Competitive; Brain; Caffeine; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrazines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Tritium; Xanthines | 1999 |
Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: does it act on an A3 adenosine receptor?
Topics: Adenosine; Animals; Astrocytes; Brain; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Extracellular Space; Guanosine; Mice; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Theophylline; Triazoles; Xanthines | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes.
Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Indole Alkaloids; Kinetics; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Plant Extracts; Quinazolines; Structure-Activity Relationship; Substrate Specificity; Theophylline | 2002 |
Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Caffeine; CHO Cells; Cricetinae; Deoxyglucose; Dimerization; Flavins; Glucose; Kinetics; Monosaccharide Transport Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Quinazolines; Recombinant Fusion Proteins; Theophylline; Transfection; Triazoles | 2002 |
Adenosine uptake inhibition ameliorates cerulein-induced acute pancreatitis in mice.
Topics: Acute Disease; Adenosine; Amylases; Animals; Biological Transport; Ceruletide; Dipyridamole; Female; Lipase; Mice; Mice, Inbred BALB C; Models, Chemical; Pancreatitis; Piperazines; Pyrimidinones; Quinazolines; Theophylline | 2002 |
Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa, in rats.
Topics: Alkaloids; Animals; Area Under Curve; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Induction; Evodia; Half-Life; Indole Alkaloids; Intubation, Gastrointestinal; Kidney; Lung; Male; Microdialysis; Microsomes, Liver; Oxazines; Plants, Medicinal; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Theophylline; Time Factors | 2005 |
Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Enzyme Inhibitors; Heart Rate; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Protein Kinase C; Quinazolines; Rabbits; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-1; Staurosporine; Theophylline; Tyramine; Vasodilator Agents | 2005 |
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
Topics: 2-Aminopurine; Adenine; Adjuvants, Immunologic; Animals; Anti-HIV Agents; Caffeine; Cell Survival; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Dihydropyridines; Dose-Response Relationship, Drug; Female; Flavins; Humans; Interleukin-10; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Organophosphonates; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Triazoles; Tumor Necrosis Factor-alpha | 2006 |
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles | 2007 |
Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.
Topics: 5'-Nucleotidase; Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glioma; Humans; Indomethacin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Time Factors; Triazoles; Xanthines | 2007 |
Application of a novel symmetrical shape factor to gastroretentive matrices as a measure of swelling synchronization and its impact on drug release kinetics under standard and modified dissolution conditions.
Topics: Delayed-Action Preparations; Diltiazem; Drug Carriers; Excipients; Hypromellose Derivatives; Kinetics; Methylcellulose; Polyethylene Glycols; Povidone; Quinazolines; Solubility; Tablets; Technology, Pharmaceutical; Theophylline | 2009 |
Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.
Topics: Adenine; Animals; Anti-Inflammatory Agents; Case-Control Studies; Dexamethasone; Drug Resistance; Histone Deacetylase 2; Humans; Leukocytes, Mononuclear; Mice; Oxidative Stress; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Quinazolines; RNA Interference; Smoking; Theophylline; Tobacco Smoke Pollution | 2010 |
Synthesis and cAMP-dependent phosphodiesterase inhibition of novel thiazoloquinazoline derivatives.
Topics: Animals; Cattle; Cyclic AMP; Inhibitory Concentration 50; Phosphodiesterase Inhibitors; Quinazolines; Structure-Activity Relationship; Theophylline | 2011 |
Effects of rutaecarpine on the metabolism and urinary excretion of caffeine in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Drug Interactions; Enzyme Induction; Indole Alkaloids; Quinazolines; Rats; Rats, Sprague-Dawley; Theobromine; Theophylline; Vasodilator Agents | 2011 |
Methylxanthine reversal of opioid-induced respiratory depression in the neonatal rat: mechanism and location of action.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Apnea; Brain Stem; Carotid Body; Central Nervous System Stimulants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Phrenic Nerve; Quinazolines; Rats, Sprague-Dawley; Respiration; Theobromine; Theophylline; Tissue Culture Techniques; Triazoles; Xanthines | 2014 |
Screening of cathepsin B inhibitors in traditional Chinese medicine by capillary electrophoresis with immobilized enzyme microreactor.
Topics: Amaryllidaceae Alkaloids; Cathepsin B; Drug Discovery; Drugs, Chinese Herbal; Electrophoresis, Capillary; Enzymes, Immobilized; Feasibility Studies; Indole Alkaloids; Indolizines; Kaempferols; Molecular Docking Simulation; Quinazolines; Theophylline | 2019 |