Compounds > quinazolines
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quinazolines and tetradecanoylphorbol acetate

quinazolines has been researched along with tetradecanoylphorbol acetate in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.78)18.7374
1990's10 (27.78)18.2507
2000's15 (41.67)29.6817
2010's8 (22.22)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Arkin, H; Holland, JF; Ohnuma, T; Schwartz, GK1
Muir, JG; Murray, AW1
Bollen, M; De Smedt, H; Himpens, B1
Nishikawa, T; Omura, M; Sasano, H; Suematsu, S1
Dobson, JG; Ethier, MF1
Conway, AM; Pyne, NJ; Pyne, S; Tolan, D1
Earp, HS; Graves, LM; Lee, JW; Li, X1
Díaz, E; Flores, I; Jones, DR; Martinez, C; Mérida, I1
Casida, JE; Rowlands, JC1
Abd-Elfattah, AS; Sholley, MM; Taher, MM1
Farrelly, ER; Ho, JJ; Kim, YS1
Bates, SE; Bishop, PC; Blagosklonny, MV; Fojo, T; Robey, R1
Bode, AM; Chen, N; Dong, Z; Liu, G; Ma, WY; She, QB; Wu, E1
Ao, Y; Fukumoto, H; Kuroki, T; Mori, M; Naruse, I; Nishio, K; Ohmori, T; Saijo, N1
Enrich, C; Lladó, A; Tebar, F1
Dartt, DA; Hodges, RR; Tepavcevic, V; Zoukhri, D1
Mattingly, RR; Menard, RE1
Barki-Harrington, L; El-Shewy, HM; Kelly, FL; Luttrell, LM1
Bolotin, D; Chu, DH; Fuchs, E; Polak, L; Wang, X; Williams, T1
Cerdá-Nicolás, M; Hamburger, M; Potterat, O; Recio, MC; Ríos, JL1
Casas-González, P; García-Sáinz, JA1
Chang, S; Chen, CF; Chen, CH; Chen, CM; Chen, KT; Hou, YC; Ko, HC; Liou, KT; Shen, YC; Wang, WY; Wang, YH1
Abel, J; Cline, JE; Fritsche, E; Moors, M1
Chen, X; Li, J; Peng, S; Tai, P; Xia, G; Xu, B; Yan, J; Zhang, M; Zhou, B1
Ebensperger, RA; Edwards, AM; Foncea, RE; Galarce, GD; Pessoa-Mahana, CD; Pessoa-Mahana, H1
Ashton, GH; Baldeschi, C; Brunton, VG; Canel, M; Doyle, B; Frame, MC; Green, TP; Mackintosh, LJ; Mason, SM; Sansom, OJ; Serrels, A; Serrels, B1
Budde, K; Kramer, S; Ladhoff, J; Lorkowski, C; Mashreghi, MF; Matz, M; Neumayer, HH; Weber, U1
Chao, DC; Ho, TY; Hsiang, CY; Kao, ST; Li, CC; Liang, JA; Lin, LJ; Lo, HY; Wu, SL1
Chang, CS; Chao, DC; Ho, TY; Hsiang, CY; Huang, HC; Kao, ST; Liang, JA; Lin, LJ; Wu, SL1
Eggo, MC; Susarla, R; Watkinson, JC1
Han, NR; Jeong, HJ; Kim, HM; Moon, PD1
Andritsos, L; Awan, FT; Blachly, JS; Byrd, JC; Cannon, M; Chen, CS; El-Gamal, D; Jones, J; LaFollette, TD; Lapalombella, R; Lehman, A; Maddocks, K; Williams, E; Williams, K; Woyach, JA; Wu, CH; Zhang, X; Zhong, Y1
Münz, C; Nytko, KJ; Reichenbach, J; Romao, S; Siler, U; Tejera, E1
Ma, Y; Shi, H; Yi, Y; Zhang, T1
Alex, VV; Anto, RJ; Bava, SV; Chittalakkottu, S; Nisthul A, A; Retnakumari, AP; Shankar G, M; Sundaram, S1
Ding, J; Fukuda, S; Imaizumi, T; Karasawa, T; Kawaguchi, S; Kikuchi, H; Matsumiya, T; Numao, N; Sakuraba, H; Seya, K1

Other Studies

36 other study(ies) available for quinazolines and tetradecanoylphorbol acetate

ArticleYear
Protein kinase C activity and multidrug resistance in MOLT-3 human lymphoblastic leukemia cells resistant to trimetrexate.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Alkaloids; Cell Division; Drug Resistance; Humans; In Vitro Techniques; Leukemia, Lymphoid; Protein Kinase C; Quinazolines; Staurosporine; Tetradecanoylphorbol Acetate; Trimetrexate; Tumor Cells, Cultured

1991
Bombesin and phorbol ester stimulate phosphatidylcholine hydrolysis by phospholipase C: evidence for a role of protein kinase C.
    Journal of cellular physiology, 1987, Volume: 130, Issue:3

    Topics: Animals; Bombesin; Carcinogens; Cells, Cultured; Hydrolysis; Kinetics; Mice; Phosphatidylcholines; Phospholipids; Protein Kinase C; Quinazolines; Tetradecanoylphorbol Acetate; Type C Phospholipases

1987
Modulation of nucleocytosolic [Ca2+] gradient in smooth muscle by protein phosphorylation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1994, Volume: 8, Issue:11

    Topics: Adenosine Triphosphate; Animals; Benzoquinones; Calcium; Cell Line; Cell Nucleus; Colforsin; Cricetinae; Cytosol; Diacylglycerol Kinase; Epidermal Growth Factor; Ethers, Cyclic; Homeostasis; Kinetics; Lactams, Macrocyclic; Leiomyosarcoma; Marine Toxins; Mesocricetus; Models, Biological; Muscle, Smooth; Okadaic Acid; Oxazoles; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Protein Kinase C; Protein Kinases; Protein Tyrosine Phosphatases; Quinazolines; Quinazolinones; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1994
Regulation of expression of the steroidogenic acute regulatory (StAR) protein by ACTH in bovine adrenal fasciculata cells.
    Biochemical and biophysical research communications, 1996, Jun-05, Volume: 223, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Bucladesine; Calcimycin; Cattle; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hydrocortisone; Immunohistochemistry; Isoquinolines; Kinetics; Naphthalenes; Phosphoproteins; Quinazolines; Sulfonamides; Tetradecanoylphorbol Acetate; Zona Fasciculata

1996
Adenosine stimulation of DNA synthesis in human endothelial cells.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins

1997
Sphingosine prevents diacylglycerol signaling to mitogen-activated protein kinase in airway smooth muscle.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: 1-Butanol; Animals; Bradykinin; Butanols; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Diacylglycerol Kinase; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Kinetics; Muscle, Smooth; Palmitic Acid; Phosphatidate Phosphatase; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Platelet-Derived Growth Factor; Protein Kinase C; Quinazolines; Quinazolinones; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Trachea

1997
Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway.
    The EMBO journal, 1998, May-01, Volume: 17, Issue:9

    Topics: Angiotensin II; Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; GTP-Binding Proteins; Humans; Liver; Protein Kinase C; Protein-Tyrosine Kinases; Quinazolines; Rats; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation

1998
Interleukin-2 stimulates a late increase in phosphatidic acid production in the absence of phospholipase D activation.
    FEBS letters, 1998, Aug-14, Volume: 433, Issue:1-2

    Topics: 3T3 Cells; Animals; Cell Line; Diacylglycerol Kinase; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-2; Isoenzymes; Mice; Phosphatidic Acids; Phospholipase D; Piperidines; Quinazolines; Quinazolinones; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate

1998
NADH: ubiquinone oxidoreductase inhibitors block induction of ornithine decarboxylase activity in MCF-7 human breast cancer cells.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:5

    Topics: Breast Neoplasms; Electron Transport Complex I; Enzyme Induction; Epithelial Cells; Estradiol; Female; Humans; Insulin-Like Growth Factor I; NADH, NADPH Oxidoreductases; Ornithine Decarboxylase; Quinazolines; RNA, Messenger; Rotenone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uncoupling Agents

1998
Sphingosine induces phospholipase D and mitogen activated protein kinase in vascular smooth muscle cells.
    Biochemistry and molecular biology international, 1998, Volume: 46, Issue:5

    Topics: Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Diacylglycerol Kinase; Enzyme Activation; Ethanol; Glycerophospholipids; Muscle, Smooth, Vascular; Phosphatidic Acids; Phospholipase D; Piperidines; Protein Kinase C; Quinazolines; Quinazolinones; Rats; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases

1998
Phorbol ester reduces phosphorylation of epidermal growth factor receptor in pancreatic cancer cells by activation of a tyrosine phosphatase.
    Biochemical and biophysical research communications, 1999, Nov-30, Volume: 265, Issue:3

    Topics: Cell Membrane; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Kinetics; Organometallic Compounds; Pancreatic Neoplasms; Phenanthrolines; Phosphorylation; Protein Tyrosine Phosphatases; Quinazolines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrphostins

1999
Loss of cell cycle control allows selective microtubule-active drug-induced Bcl-2 phosphorylation and cytotoxicity in autonomous cancer cells.
    Cancer research, 2000, Jul-01, Volume: 60, Issue:13

    Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Cell Survival; Enzyme Inhibitors; Epidermal Growth Factor; Female; HL-60 Cells; Humans; Microtubules; Mitosis; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured; Tyrphostins

2000
Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; ErbB Receptors; Ligands; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Phenylalanine; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Quinazolines; Signal Transduction; Tetradecanoylphorbol Acetate; Thiophenes; Transcription Factor AP-1; Transcriptional Activation; Tyrphostins

2001
Antitumor activity of the selective epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) Iressa (ZD1839) in an EGFR-expressing multidrug-resistant cell line in vitro and in vivo.
    International journal of cancer, 2002, Mar-10, Volume: 98, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Female; Gefitinib; Humans; K562 Cells; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms; Phosphorylation; Quinazolines; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2002
Role of calmodulin in the modulation of the MAPK signalling pathway and the transactivation of epidermal growth factor receptor mediated by PKC.
    FEBS letters, 2002, Apr-24, Volume: 517, Issue:1-3

    Topics: Animals; Calmodulin; Chlorocebus aethiops; COS Cells; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Mitogen-Activated Protein Kinases; Phenylalanine; Protein Kinase C; Quinazolines; ras Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thiophenes; Transcriptional Activation; Tyrphostins

2002
Signal transduction pathways used by EGF to stimulate protein secretion in rat lacrimal gland.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:3

    Topics: Animals; Blotting, Western; Calcium; Carbachol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Eye Proteins; Lacrimal Apparatus; Male; Peroxidase; Phenylephrine; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrphostins

2003
Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: Androstadienes; Animals; Carbachol; cdc42 GTP-Binding Protein; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Kinetics; Lysophospholipids; Maleimides; Mice; Models, Biological; Myelin Basic Protein; NIH 3T3 Cells; p21-Activated Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Quinazolines; rac GTP-Binding Proteins; ras Proteins; Receptor, Muscarinic M2; Receptors, Cell Surface; rho GTP-Binding Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tyrphostins; Wortmannin

2003
Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I.
    Molecular endocrinology (Baltimore, Md.), 2004, Volume: 18, Issue:11

    Topics: Animals; Cell Line; Chlorocebus aethiops; Endocytosis; ErbB Receptors; Humans; Insulin-Like Growth Factor I; Metalloendopeptidases; Mice; Mitogen-Activated Protein Kinase 3; Paracrine Communication; Phenylalanine; Phosphorylation; Quinazolines; Rats; Receptors, Somatomedin; Tetradecanoylphorbol Acetate; Thiophenes; Tyrosine; Tyrphostins

2004
AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis.
    The Journal of cell biology, 2006, Jan-30, Volume: 172, Issue:3

    Topics: Animals; Animals, Newborn; Calcium; Caspase 3; Caspases; Cell Proliferation; Chromatin Immunoprecipitation; Chromones; Dermis; DNA; Embryo, Mammalian; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; ErbB Receptors; Gene Expression; Gene Expression Regulation; Hair Diseases; Integrases; Keratinocytes; Keratins; Ki-67 Antigen; MAP Kinase Signaling System; Mice; Mice, Transgenic; Morpholines; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Skin; Skin Abnormalities; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transforming Growth Factor alpha; Tyrphostins

2006
Anti-inflammatory and antiallergic activity in vivo of lipophilic Isatis tinctoria extracts and tryptanthrin.
    Planta medica, 2006, Volume: 72, Issue:6

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Carrageenan; Drugs, Chinese Herbal; Edema; Female; Hypersensitivity; Isatis; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Quinazolines; Tetradecanoylphorbol Acetate

2006
Role of epidermal growth factor receptor transactivation in alpha1B-adrenoceptor phosphorylation.
    European journal of pharmacology, 2006, Aug-07, Volume: 542, Issue:1-3

    Topics: Adrenergic alpha-Agonists; Androstadienes; Animals; Antibodies; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Endothelin-1; Epidermal Growth Factor; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Norepinephrine; Phenylalanine; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Thiophenes; Tyrphostins; Wortmannin

2006
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells.
    European journal of pharmacology, 2007, Jan-26, Volume: 555, Issue:2-3

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Ethanol; Evodia; Humans; Hydrazines; Indole Alkaloids; Mice; Microglia; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Picrates; Plant Extracts; Quinazolines; Reactive Oxygen Species; Synephrine; Tetradecanoylphorbol Acetate

2007
ERK-dependent and -independent pathways trigger human neural progenitor cell migration.
    Toxicology and applied pharmacology, 2007, May-15, Volume: 221, Issue:1

    Topics: Astrocytes; Blotting, Western; Cell Differentiation; Cell Movement; Cell Survival; Cells, Cultured; Flavonoids; Humans; Indoles; Maleimides; Methylmercury Compounds; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Protein Kinase C; Pyrimidines; Quinazolines; Signal Transduction; Spheroids, Cellular; src-Family Kinases; Stem Cells; Sulfonamides; Tetradecanoylphorbol Acetate; Tyrphostins

2007
Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes.
    The Journal of endocrinology, 2008, Volume: 197, Issue:2

    Topics: Animals; Cells, Cultured; Cumulus Cells; Epidermal Growth Factor; ErbB Receptors; Female; Follicle Stimulating Hormone; Meiosis; Oocytes; Phosphorylation; Protein Kinase C; Quinazolines; Receptors, Androgen; Swine; Tetradecanoylphorbol Acetate; Tyrphostins

2008
Biological evaluation of novel 6-Arylbenzimidazo[1,2-c]quinazoline derivatives as inhibitors of LPS-induced TNF-alpha secretion.
    Biological research, 2008, Volume: 41, Issue:1

    Topics: Anti-Inflammatory Agents; HL-60 Cells; Humans; Lipopolysaccharides; Quinazolines; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2008
A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model.
    Carcinogenesis, 2009, Volume: 30, Issue:2

    Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Keratinocytes; Keratosis; Male; Mice; Middle Aged; Papilloma; Precancerous Conditions; Quinazolines; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate

2009
Effects of the new immunosuppressive agent AEB071 on human immune cells.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:7

    Topics: CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cytokines; Dendritic Cells; Humans; Immunosuppressive Agents; Ionomycin; K562 Cells; Killer Cells, Natural; Leukocytes, Mononuclear; Protein Kinase C; Pyrroles; Quinazolines; Tetradecanoylphorbol Acetate

2010
Evodiamine inhibits 12-O-tetradecanoylphorbol-13-acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Transformation, Neoplastic; Evodia; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Humans; Phosphorylation; Plant Extracts; Quinazolines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Transfection

2011
Inhibitory effects of Zuo-Jin-Wan and its alkaloidal ingredients on activator protein 1, nuclear factor-κB, and cellular transformation in HepG2 cells.
    Fitoterapia, 2011, Volume: 82, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Coptis; Drugs, Chinese Herbal; Evodia; Hep G2 Cells; Humans; Liver Neoplasms; NF-kappa B; Plant Extracts; Quinazolines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2011
Regulation of human thyroid follicular cell function by inhibition of vascular endothelial growth factor receptor signalling.
    Molecular and cellular endocrinology, 2012, Apr-04, Volume: 351, Issue:2

    Topics: Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organotechnetium Compounds; Phosphorylation; Plasminogen Activators; Protein Kinase C; Quinazolines; Rats; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Vascular Endothelial Growth Factor A

2012
Tryptanthrin ameliorates atopic dermatitis through down-regulation of TSLP.
    Archives of biochemistry and biophysics, 2014, Jan-15, Volume: 542

    Topics: Animals; Calcimycin; Calcium Ionophores; Cell Line; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Down-Regulation; Humans; Male; Mast Cells; Mice; Quinazolines; Skin; Spleen; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin

2014
PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
    Blood, 2014, Aug-28, Volume: 124, Issue:9

    Topics: Apoptosis; beta Catenin; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Microenvironment; Wnt Signaling Pathway

2014
Defective nuclear entry of hydrolases prevents neutrophil extracellular trap formation in patients with chronic granulomatous disease.
    The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:6

    Topics: Adenine; Androstadienes; Benzylamines; Candida albicans; Cell Nucleus; Extracellular Traps; Granulomatous Disease, Chronic; Histones; Humans; Hydrolases; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Wortmannin

2015
Inhibition of the Ras-ERK pathway in mitotic COS7 cells is due to the inability of EGFR/Raf to transduce EGF signaling to downstream proteins.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Animals; Caveolins; Cell Line; Chlorocebus aethiops; Clathrin; COS Cells; Endocytosis; Endosomes; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; GRB2 Adaptor Protein; MAP Kinase Signaling System; Nocodazole; Phosphorylation; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Quinazolines; raf Kinases; Shc Signaling Adaptor Proteins; Tetradecanoylphorbol Acetate; Tyrphostins

2016
Pre-clinical evidences for the efficacy of tryptanthrin as a potent suppressor of skin cancer.
    Cell proliferation, 2020, Volume: 53, Issue:1

    Topics: Animals; Drug Screening Assays, Antitumor; gamma-Aminobutyric Acid; Ki-67 Antigen; Mice; Neoplasm Proteins; Proliferating Cell Nuclear Antigen; Quinazolines; Skin Neoplasms; Tetradecanoylphorbol Acetate

2020
Tryptanthrin attenuates TLR3-mediated STAT1 activation in THP-1 cells.
    Immunologic research, 2022, Volume: 70, Issue:5

    Topics: Anti-Inflammatory Agents; Humans; Interferon Regulatory Factor-3; Interferon-beta; Janus Kinases; Ligands; Lipopolysaccharides; Poly I-C; Quinazolines; RNA, Messenger; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate; THP-1 Cells; Toll-Like Receptor 3

2022