Compounds > quinazolines
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quinazolines and tanespimycin

quinazolines has been researched along with tanespimycin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garber, K1
Cavanaugh, SX; Hammond, LA; Thomas, CR1
Kwan, W; Liu, S; Lubieniecka, JM; Nielsen, TO; Terry, J1
Arnold, B; Pollack, IF; Premkumar, DR1
Neckers, L; Pashtan, I; Tsutsumi, S; Wang, S; Xu, W1
Chang, Y; Chesebrough, J; Coats, S; Coffman, KT; Fazenbaker, CA; Gooya, J; Jackson, D; Jallal, B; Leow, CC; Weng, D1
Arnould, L; Coudert, B; Favier, L; Fumoleau, P; Guiu, S1
Bueno, R; Corson, JM; Fletcher, JA; Flynn, DL; Hubert, C; Ou, WB; Sugarbaker, DJ1
Breinig, M; Chiosis, G; Dienemann, H; Giaccone, G; Goeppert, B; Harjung, A; Hartmann, A; Kern, MA; Malz, M; Mayer, P; Neumann, O; Penzel, R; Rieker, RJ; Schirmacher, P1
Arango, BA; Cohen, EE; Perez, CA; Raez, LE; Santos, ES1
Booth, L; Chen, CS; Cruickshanks, N; Dent, P; Grant, S; Ridder, T1
Brouwers, AH; de Vries, EG; Lub-de Hooge, MN; Oude Munnink, TH; Schröder, CP; Timmer-Bosscha, H; Vedelaar, SR1

Reviews

2 review(s) available for quinazolines and tanespimycin

ArticleYear
[Management of metastatic HER2-positive breast cancer: present and future].
    Bulletin du cancer, 2010, Volume: 97, Issue:3

    Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Bevacizumab; Brain Neoplasms; Breast Neoplasms; Disease Progression; Female; Heart; Humans; Lactams, Macrocyclic; Lapatinib; Letrozole; Neoplasm Proteins; Nitriles; Quinazolines; Quinolines; Receptor, ErbB-2; Trastuzumab; Triazoles

2010
Novel molecular targeted therapies for refractory thyroid cancer.
    Head & neck, 2012, Volume: 34, Issue:5

    Topics: Angiogenesis Inhibitors; Anilides; Antineoplastic Agents; Axitinib; Benzamides; Benzenesulfonates; Benzoquinones; Bibenzyls; Boronic Acids; Bortezomib; Depsipeptides; ErbB Receptors; Gefitinib; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Imatinib Mesylate; Imidazoles; Indazoles; Indoles; Lactams, Macrocyclic; Lenalidomide; Niacinamide; Oligonucleotides; Phenylurea Compounds; Piperazines; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrazines; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolines; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sulfonamides; Sunitinib; Thalidomide; Thyroid Neoplasms; Valproic Acid; Vorinostat

2012

Other Studies

10 other study(ies) available for quinazolines and tanespimycin

ArticleYear
Synthetic lethality: killing cancer with cancer.
    Journal of the National Cancer Institute, 2002, Nov-20, Volume: 94, Issue:22

    Topics: Animals; Antineoplastic Agents; Benzamides; Benzoquinones; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; Gefitinib; Genes, Tumor Suppressor; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Indoles; Lactams, Macrocyclic; Mutation; Neoplasms; Phosphoric Monoester Hydrolases; Piperazines; PTEN Phosphohydrolase; Pyrimidines; Pyrroles; Quinazolines; Rifabutin; Signal Transduction; Sirolimus; Transcription Factors; Tumor Suppressor Proteins

2002
An image worth a thousand lives?
    Nature biotechnology, 2004, Volume: 22, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzoquinones; Bibenzyls; Diagnostic Imaging; Down-Regulation; ErbB Receptors; Gefitinib; Heterocyclic Compounds, 1-Ring; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Magnetic Resonance Imaging; Molecular Probe Techniques; Mutation; Neoplasms; Phthalazines; Physiological Phenomena; Positron-Emission Tomography; Protein Binding; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptors, Vascular Endothelial Growth Factor; Rifabutin; Stilbenes; Tissue Distribution; Trastuzumab

2004
Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-01, Volume: 11, Issue:15

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Benzamides; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; ErbB Receptors; Flow Cytometry; Gefitinib; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Immunoblotting; Immunohistochemistry; In Situ Hybridization, Fluorescence; In Vitro Techniques; Inhibitory Concentration 50; Lactams, Macrocyclic; Piperazines; Prognosis; Pyrimidines; Pyrroles; Quinazolines; Rifabutin; Sarcoma, Synovial; Trastuzumab

2005
Cooperative inhibitory effect of ZD1839 (Iressa) in combination with 17-AAG on glioma cell growth.
    Molecular carcinogenesis, 2006, Volume: 45, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Caspase 3; Caspases; Cell Proliferation; Drug Combinations; Enzyme Activation; ErbB Receptors; Fibroblasts; G1 Phase; Gefitinib; Glioma; Humans; Lactams, Macrocyclic; Lung; Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Quinazolines; Rifabutin; Signal Transduction; Tumor Stem Cell Assay

2006
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition.
    Cell cycle (Georgetown, Tex.), 2008, Sep-15, Volume: 7, Issue:18

    Topics: Animals; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Enzyme Activation; Gefitinib; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Receptor, ErbB-3; Serum; Signal Transduction

2008
Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2-positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lapatinib; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; Trastuzumab; Xenograft Model Antitumor Assays

2009
Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma.
    Neoplasia (New York, N.Y.), 2011, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Axl Receptor Tyrosine Kinase; Benzoquinones; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Interactions; Enzyme Activation; ErbB Receptors; Gefitinib; HSP90 Heat-Shock Proteins; Humans; Indoles; Lactams, Macrocyclic; Mesothelioma; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Sulfones

2011
Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Apr-15, Volume: 17, Issue:8

    Topics: Aged; Apoptosis; Benzoquinones; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Gefitinib; HSP90 Heat-Shock Proteins; Humans; Immunohistochemistry; Infant; Infant, Newborn; Lactams, Macrocyclic; Male; Middle Aged; Neoplasms, Glandular and Epithelial; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, IGF Type 1; RNA Interference; Signal Transduction; Thymus Neoplasms

2011
OSU-03012 interacts with lapatinib to kill brain cancer cells.
    Cancer biology & therapy, 2012, Volume: 13, Issue:14

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy-Related Protein 5; Beclin-1; Benzoquinones; Brain Neoplasms; Celecoxib; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; ErbB Receptors; Genes, erbB-1; Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lapatinib; Lipids; MAP Kinase Kinase 1; Membrane Proteins; Microtubule-Associated Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Pyrazoles; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-4; RNA Interference; RNA, Small Interfering; Signal Transduction; Sulfonamides

2012
Lapatinib and 17AAG reduce 89Zr-trastuzumab-F(ab')2 uptake in SKBR3 tumor xenografts.
    Molecular pharmaceutics, 2012, Nov-05, Volume: 9, Issue:11

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Blotting, Western; Breast Neoplasms; Cell Proliferation; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Genes, erbB-1; HSP90 Heat-Shock Proteins; Humans; Immunoenzyme Techniques; Immunoglobulin Fab Fragments; Lactams, Macrocyclic; Lapatinib; Male; Mice; Mice, Inbred BALB C; Quinazolines; Receptor, ErbB-2; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2012