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quinazolines and sgb 1534

quinazolines has been researched along with sgb 1534 in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199017 (89.47)18.7374
1990's2 (10.53)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiba, K; Hayashi, Y; Hisa, H; Satoh, S; Suzuki-Kusaba, M1
Nagatomo, T; Tsuchihashi, H1
Koga, T; Sakai, K; Shiraki, Y1
Akima, M; Imagawa, J; Sakai, K1
Sugimoto, T; Uchida, Y1
Aono, J; Ishizuka, N; Nabata, H; Sakai, K2
Flores, F; Follmer, C; Ishida, Y; Satake, N; Shibata, S; Suh, TK; Ueda, S1
Aono, J; Sakai, K2
Imagawa, J; Nabata, H; Sakai, K1
Matsumoto, M; Minami, M; Nagao, A; Saito, H; Togashi, H; Yoshioka, M1
Aono, J; Nagatomo, T; Nakamura, T; Tajiri, A; Tsuchihashi, H1
Sonoki, H; Sugimoto, T; Tomaru, T; Uchida, Y1
Aono, J; Hokibara, R; Nagatomo, T; Nakamura, T; Tanaka, Y; Tsuchihashi, H1
Imagawa, J; Sakai, K1
Akima, M; Kuromaru, O; Sakai, K; Yoshizawa, M1
Ishikawa, S1
Chan, CH; Chern, JW; Chien, SL; Lai, YJ; Lu, GY; Shiau, CY; Tao, PL; Yen, MH1

Other Studies

19 other study(ies) available for quinazolines and sgb 1534

ArticleYear
Effects of a novel alpha 1-adrenoceptor antagonist, SGB-1534, on adrenergically induced renal vasoconstriction in dogs.
    European journal of pharmacology, 1990, Feb-13, Volume: 176, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Electric Stimulation; Female; Guanabenz; Male; Methoxamine; Prazosin; Quinazolines; Renal Circulation; Sympathetic Nervous System; Vasoconstriction

1990
Alpha-blocking potencies of antihypertensive agents (prazosin, terazosin, bunazosin, SGB-1534 and ketanserin) having with quinazoline or quinazolinedione as assessed by radioligand binding assay methods in rat brain.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brain; Cell Membrane; Clonidine; Dihydroalprenolol; Ketanserin; Male; Prazosin; Quinazolines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1989
Characterization of a novel alpha 1-adrenoceptor antagonist, SGB-1534, in contractile response of isolated canine arterial and venous smooth muscle to exogenous noradrenaline: comparison with prazosin, phentolamine and yohimbine.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Yohimbine

1989
In vivo experiments for the evaluation of alpha 1-adrenoceptor antagonistic effects of SGB-1534 on canine urethra.
    European journal of pharmacology, 1989, Aug-11, Volume: 167, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hypogastric Plexus; Phenylephrine; Prazosin; Quinazolines; Urethra

1989
[Cardiovascular effect of a novel substance, 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl] ethyl]-2,4 (1H, 3H)-quinazolinedione monohydrochloride (SGB 1534)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Dogs; Heart Rate; Myocardial Contraction; Phenylephrine; Quinazolines; Vascular Resistance

1985
Mechanism of the hypotensive effect of a novel phenylpiperazine derivative, SGB-1534: antagonism at alpha 1-adrenergic and 5-HT2 receptors.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Decerebrate State; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Piperidines; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Serotonin Antagonists

1985
Potent alpha-adrenoceptor blocking action of SGB-1534, a new quinazoline antihypertensive agent in vitro experiments.
    General pharmacology, 1986, Volume: 17, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Basilar Artery; Cats; Coronary Vessels; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Prazosin; Quinazolines; Rabbits; Vas Deferens

1986
Effects of a new antihypertensive agent, SGB-1534, on rat platelet aggregation.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Malondialdehyde; Platelet Aggregation; Quinazolines; Rats; Rats, Inbred Strains; Serotonin; Vasoconstriction

1986
Comparison of cardiovascular effects of SGB-1534 and prazosin, selective alpha 1-adrenoceptor antagonists, in anesthetized dogs.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:1

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; Phenylephrine; Prazosin; Quinazolines; Renal Circulation; Vascular Resistance; Vasoconstriction

1987
Effects of SGB-1534, a new synthesized phenylpiperazine derivative, on blood pressure and heart rate in stroke-prone spontaneously hypertensive rats.
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1988, Volume: 63, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Blood Pressure; Catecholamines; Heart Rate; Male; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1988
Effect of 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monophydrochloride (SGB-1534), an antihypertensive agent, on 3H-prazosin and 3H-p-aminoclonidine binding to alpha 1- and alpha 2-adrenoceptors in dog brain and aorta.
    Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Brain; Clonidine; Dogs; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Prazosin; Quinazolines; Receptors, Adrenergic, alpha

1988
Investigations into the mechanism of the antihypertensive effect of SGB-1534, a novel alpha 1-adrenoceptor antagonist, in rats.
    Japanese journal of pharmacology, 1988, Volume: 48, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1988
[Effects of prazosin, SGB-1534, dobutamine and isoproterenol on congestive heart failure in dogs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Disease Models, Animal; Dobutamine; Dogs; Heart Failure; Hemodynamics; Isoproterenol; Prazosin; Quinazolines

1988
Effects of ketanserin and 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monohydrochloride (SGB-1534), anti-hypertensive agents, on 3H-serotonin and 3H-ketanserin bindings to serotonergic (5HT1 and 5HT2) receptors in dog brain
    Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Brain Chemistry; Dogs; Female; In Vitro Techniques; Ketanserin; Male; Muscle, Smooth, Vascular; Quinazolines; Receptors, Serotonin; Serotonin

1988
Further evaluation of the selectivity of a novel antihypertensive agent, SGB-1534, for peripheral alpha 1-adrenoceptors in the spinally anesthetized dog.
    European journal of pharmacology, 1986, Nov-19, Volume: 131, Issue:2-3

    Topics: Anesthesia, Spinal; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Female; Male; Methoxamine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Regional Blood Flow; Yohimbine

1986
Antihypertensive effects of a novel phenylpiperazine derivative, SGB-1534, on several hypertensive models of rats.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1

    Topics: Animals; Antihypertensive Agents; Desoxycorticosterone; Hypertension; Hypertension, Renal; Lethal Dose 50; Male; Phentolamine; Posture; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin

1985
Cardiovascular effects of a novel antihypertensive agent, SGB-1534, in miniature pigs.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:1

    Topics: Anesthesia; Animals; Antihypertensive Agents; Coronary Circulation; Epinephrine; Female; Hemodynamics; Male; Quinazolines; Swine; Swine, Miniature; Time Factors

1985
Effects of a new alpha 1-adrenoceptor blocking agent, 3-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-(1H,3H)-quinazoline-2, 4-dione monohydrochloride (SGB1534), on electrical and mechanical properties of guinea-pig mesenteric artery.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinazolines; Serotonin; Synaptic Transmission

1984
Studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents.
    Journal of medicinal chemistry, 1993, Jul-23, Volume: 36, Issue:15

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Quinazolines; Rats; Rats, Inbred SHR; Structure-Activity Relationship

1993