quinazolines has been researched along with sb 203580 in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 16 (64.00) | 29.6817 |
| 2010's | 7 (28.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horiuchi, M; Mita, S; Oki, K; Senda, T; Tsuji, F | 1 |
| Avkiran, M; Hearse, DJ; Snabaitis, AK | 1 |
| Buresi, MC; Buret, AG; Hollenberg, MD; MacNaughton, WK | 1 |
| Huang, XL; Lawrence, M; Madara, P; Nanavaty, UB; Pawliczak, R; Shelhamer, JH | 1 |
| Dobashi, K; Ishizuka, T; Kawata, T; Mori, M; Shimizu, Y; Tsukagoshi, H | 1 |
| Becker, JW; Cameron, PM; Fitzgerald, CE; O'Keefe, SJ; Patel, SB; Pikounis, VB; Scapin, G; Zaller, D | 1 |
| Chalothorn, D; Faber, JE; Jackson, LF; Lee, DC; Zhang, H | 1 |
| Dai, JR; Deretey, E; Foster, JE; Ng, W; Pasternak, A; Redden, PR; Reid, N; Slon-Usakiewicz, JJ; Toledo-Sherman, L | 1 |
| Bagnato, A; Di Castro, V; Elia, G; Natali, PG; Rosanò, L; Spinella, F | 1 |
| Laufer, S; Wagner, G | 1 |
| Chayama, K; Kuwahara, K; Miyata, H; Sasaki, T; Serikawa, M | 1 |
| Chakraborty, C; Lala, PK; Timoshenko, AV; Wagner, GF | 1 |
| Fukuda, Y; Goto, M; Terakawa, M; Tomimori, Y | 1 |
| Kawakami, T; Olsson, T; Yucel-Lindberg, T | 1 |
| Guo, J; Sheng, G; Warner, BW | 1 |
| Ikejima, T; Onodera, S; Tashiro, S; Wu, LJ; Yang, J | 1 |
| Kawanishi, M; Koizumi, K; Nishimura, M; Saiki, I; Sakurai, H; Shin, MS; Singhirunnusorn, P; Suzuki, S | 1 |
| Abdel-Tawab, H; Ahmed, EA; Alhazza, IM; Badr, G; Hassan, K; Saad, H; Waly, H | 1 |
| Bollinger, N; Joslin, EJ; Lauffenburger, DA; Opresko, LK; Shankaran, H; Wiley, HS | 1 |
| Chen, SC; Chiou, SJ; Chuang, LY; Guh, JY; Hwang, CC; Ko, YM; Lin, TD | 1 |
| Barth, M; Fender, AC; Fischer, JW; Hohlfeld, T; Kurt, M; Mahajan, SG; Meyer-Kirchrath, J; Rauch, BH; Sagban, TA; Schrör, K | 1 |
| Chen, J; Li, JY; Shi, JY; Su, B; Tang, L; Yang, XJ; Zhang, J; Zhao, YM | 1 |
| Jeong, YJ; Kim, CH; Kim, DJ; Kim, JC; Lee, KB; Oh, SM; Park, JH | 1 |
| Liu, Y; Shi, HL; Wu, XJ; Xie, JQ | 1 |
| Bhavan, PS; Chung, CL; Hou, SM; Hsia, CH; Hsia, CW; Huang, WC; Jayakumar, T; Sheu, JR; Wu, MP | 1 |
1 review(s) available for quinazolines and sb 203580
| Article | Year |
|---|---|
Small molecular anti-cytokine agents.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Caspase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytokines; Humans; Hydroxamic Acids; Imidazoles; Matrix Metalloproteinase Inhibitors; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridazines; Pyridines; Pyrimidines; Quinazolines; Structure-Activity Relationship; Succinates; Thiazoles; Tumor Necrosis Factor-alpha; Urea | 2006 |
24 other study(ies) available for quinazolines and sb 203580
| Article | Year |
|---|---|
Effects of mitogen-activated protein kinase inhibitors or phosphodiesterase inhibitors on interleukin-1-induced cytokines production in synovium-derived cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Calcium-Calmodulin-Dependent Protein Kinases; Cytokines; Dose-Response Relationship, Drug; Humans; Imidazoles; Interleukin-1; Phosphodiesterase Inhibitors; Pyridines; Pyrrolidinones; Quinazolines; Rolipram; Synovial Membrane | 1999 |
Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes.
Topics: Animals; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Genistein; Hydrogen Peroxide; Imidazoles; Immunoblotting; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Plant Proteins; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Rats; Rats, Wistar; Sarcolemma; Signal Transduction; Sodium-Hydrogen Exchangers; src-Family Kinases; Tyrphostins | 2002 |
Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway.
Topics: Androstadienes; Butadienes; Cell Line; Chlorides; Epithelial Cells; Humans; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Nitriles; Nitrobenzenes; Phospholipases A; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Pyridines; Pyrimidines; Quinazolines; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Tyrphostins; Wortmannin | 2002 |
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
Topics: Antineoplastic Agents; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Ionophores; Lung; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; Quinazolines; ras Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins | 2002 |
4-Hydroxy-2-nonenal enhances fibronectin production by IMR-90 human lung fibroblasts partly via activation of epidermal growth factor receptor-linked extracellular signal-regulated kinase p44/42 pathway.
Topics: Acetylcysteine; Aldehydes; Cell Line; Culture Media, Conditioned; ErbB Receptors; Fibroblasts; Fibronectins; Humans; Imidazoles; Lipid Peroxidation; Lung; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Pyridines; Quinazolines; Signal Transduction; Tyrphostins | 2002 |
Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Enzyme Inhibitors; Glycine; Imidazoles; Inhibitory Concentration 50; Kinetics; Mice; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Pyridazines; Pyridines; Pyrimidines; Quinazolines; Sequence Homology, Amino Acid | 2003 |
Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Anthracenes; Aorta, Thoracic; Bacterial Proteins; Benzopyrans; Butadienes; Catheterization; Cell Division; Dipeptides; ErbB Receptors; Flavonoids; Glycine; Hydroxamic Acids; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Organ Culture Techniques; Phenylephrine; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Thrombin; Tyrphostins | 2004 |
Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery.
Topics: Alkaloids; Animals; Benzophenanthridines; Binding Sites; Binding, Competitive; Catalytic Domain; Chromatography, Affinity; Drug Evaluation, Preclinical; Humans; Imidazoles; Mass Spectrometry; Mice; Molecular Structure; Peptides; Phosphorylation; Protein Binding; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Quinazolines; Receptor, EphB2; Recombinant Proteins | 2005 |
Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Induction; ErbB Receptors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor, Endothelin A; Signal Transduction; Transcriptional Activation; Tyrphostins | 2004 |
The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
Topics: Anthracenes; Bile Duct Neoplasms; Butadienes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Clone Cells; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Quinazolines; Radiation-Sensitizing Agents | 2006 |
COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Down-Regulation; Enzyme Activation; Female; Glycoproteins; Humans; Imidazoles; Lymphangiogenesis; Molecular Sequence Data; Pyrazoles; Pyridines; Pyrimidines; Quinazolines; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; RNA, Small Interfering; Structure-Activity Relationship; Vascular Endothelial Growth Factor C; Vesicular Transport Proteins | 2006 |
Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils.
Topics: Animals; Butadienes; Cell Line, Tumor; Chemokine CXCL2; Chemokines; Chymases; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Gene Expression; Humans; Imidazoles; Interleukin-8; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Neutrophils; Nitriles; Peritonitis; Pertussis Toxin; Pyridines; Quinazolines; RNA, Messenger; Serine Endopeptidases | 2006 |
Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.
Topics: Arachidonic Acid; Blotting, Western; Cells, Cultured; Child; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Imidazoles; Indoles; Interleukin-1beta; Intramolecular Oxidoreductases; Maleimides; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Prostaglandin-E Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 2006 |
Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Dose-Response Relationship, Drug; Enterocytes; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Ileum; Imidazoles; Mitochondria; Mitogen-Activated Protein Kinase 14; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Pyridines; Quinazolines; Rats; RNA Interference; RNA, Small Interfering; Signal Transduction; Time Factors; Tyrphostins | 2007 |
Nitric oxide activated by p38 and NF-kappaB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Feedback, Physiological; Humans; Imidazoles; Melanoma; Membrane Potential, Mitochondrial; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; Quinazolines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Time Factors; Tumor Suppressor Protein p53 | 2008 |
TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling.
Topics: Anthracenes; Butadienes; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Imidazoles; Lactones; MAP Kinase Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Resorcinols; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha | 2009 |
Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL).
Topics: Adenine; Amides; Animals; Antibodies, Blocking; Apoptosis; B-Lymphocytes; bcl-X Protein; Cells, Cultured; Class I Phosphatidylinositol 3-Kinases; Gene Expression Regulation; Humans; Imidazoles; Immunologic Memory; Interferon Type I; Lymphocyte Subsets; Mice; NF-kappa B; Oncogene Protein v-akt; Peptides; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyridines; Quinazolines; Receptors, Interferon; Recombinant Proteins; rho-Associated Kinases; Signal Transduction | 2010 |
Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.
Topics: Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gefitinib; Gene Regulatory Networks; Hepatocyte Growth Factor; Humans; Imidazoles; Ligands; Lysophospholipids; Mammary Glands, Human; Phosphorylation; Pyridines; Quinazolines; Signal Transduction; Transcriptional Activation; Transforming Growth Factor alpha | 2010 |
Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells.
Topics: Animals; Benzamides; Cell Line; Collagen; Cyclin D1; Dioxoles; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gefitinib; Imidazoles; Kidney; MAP Kinase Signaling System; Mice; Mitosis; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Rats; Receptors, Transforming Growth Factor beta; Smad Proteins; Transforming Growth Factor beta1; Translational Research, Biomedical | 2011 |
A novel function of FoxO transcription factors in thrombin-stimulated vascular smooth muscle cell proliferation.
Topics: Cell Proliferation; Cells, Cultured; Chromones; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Endothelium, Vascular; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Imidazoles; Morpholines; Myocytes, Smooth Muscle; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyridines; Pyrroles; Quinazolines; RNA, Small Interfering; Saphenous Vein; Thrombin | 2012 |
[Small molecule inhibitor SB203580 enhances the antitumor effect of gefitinib in PC-9 and A549 lung cancer cell lines].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Enzyme Inhibitors; Gefitinib; Humans; Imidazoles; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Quinazolines; Signal Transduction | 2013 |
RIP2/RICK-dependent cytokine production upon Yersinia enterocolitica infection in macrophages with TLR4 deficiency.
Topics: Animals; Enzyme Inhibitors; Gefitinib; Imidazoles; Interleukin-10; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinazolines; Receptor-Interacting Protein Serine-Threonine Kinase 2; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Yersinia enterocolitica; Yersinia Infections | 2013 |
Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine.
Topics: Antineoplastic Agents, Phytogenic; Berberine; Cell Adhesion; Cell Cycle; Cell Movement; Cell Proliferation; Chemokines; Chemokines, CXC; Chromones; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-8; Morpholines; Pyridines; Quinazolines; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured | 2013 |
Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB.
Topics: Animals; Disease Models, Animal; Fibrinolytic Agents; Free Radical Scavengers; Free Radicals; Humans; I-kappa B Kinase; Imidazoles; Indole Alkaloids; Male; Mice, Inbred ICR; NF-kappa B; Nitriles; P-Selectin; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Protein Kinase Inhibitors; Pulmonary Embolism; Pyridines; Quinazolines; Sulfones; Thrombosis; Transcription Factor RelA | 2022 |