Page last updated: 2024-08-21

quinazolines and rolipram

quinazolines has been researched along with rolipram in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (77.78)18.2507
2000's4 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Archer, RL; Chapin, DS; Chen, JB; Helweg, D; Johnson, JL; Koe, BK; Lebel, LA; Lowe, JA; Moore, PF; Nielsen, JA1
Howell, LL; Landrum, AM1
Bateman-Fite, R; Brackeen, MF; Clark, RL; Connolly, KM; Menius, JA; Noel, LS; Sekut, L; Stimpson, SA; Yarnall, D1
Forssmann, WG; Jonas, U; Meyer, M; Schulz-Knappe, P; Stief, CG; Taher, A; Truss, M1
Byrd, LD; Howell, LL1
Heaslip, R; Molnar-Kimber, K; Weichman, B; Yonno, L1
Becker, AJ; Forssmann, WG; Jonas, U; Meyer, M; Schulz-Knappe, P; Stief, CG; Taher, A; Truss, M; Uckert, S1
Beleta, J; Palacios, JM; Segarra, V1
Dousa, TP; Grande, JP; Johnson, RJ; Shankland, SJ; Tsuboi, Y; Walker, HJ1
Barnes, PJ; Giembycz, MA; Kelly, JJ1
Forssmann, WG; Jonas, U; Meyer, M; Stief, CG; Taher, A1
Dousa, TP; Grande, JP; Matousovic, K; Tsuboi, Y; Walker, H1
Endo, T; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Satoh, Y; Suzuguchi, T1
Horiuchi, M; Mita, S; Oki, K; Senda, T; Tsuji, F1
Bischoff, E; Jonas, U; Kühn, R; Lietz, B; Schramm, M; Stief, CG; Truss, MC; Uckert, S1
Dal Piaz, V; Giovannoni, MP1
Kim, E; Kim, JH; Kim, SH; Nam, G; Rhee, CK; Shin, JH; Yoon, CM1
Cheng, J; Grande, JP; Gray, CE; Thompson, MA; Walker, HJ; Warner, GM; Zhou, W1

Reviews

2 review(s) available for quinazolines and rolipram

ArticleYear
Second messenger systems as targets for new therapeutic agents: focus on selective phosphodiesterase inhibitors.
    Farmaco (Societa chimica italiana : 1989), 1995, Volume: 50, Issue:12

    Topics: Animals; Humans; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinazolines; Rolipram; Second Messenger Systems; Structure-Activity Relationship

1995
Phosphodiesterase 4 inhibitors, structurally unrelated to rolipram, as promising agents for the treatment of asthma and other pathologies.
    European journal of medicinal chemistry, 2000, Volume: 35, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arthritis, Rheumatoid; Asthma; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Isoenzymes; Lung Diseases, Obstructive; Molecular Structure; Phosphodiesterase Inhibitors; Quinazolines; Rolipram; Theophylline; Xanthines

2000

Other Studies

16 other study(ies) available for quinazolines and rolipram

ArticleYear
Structure-activity relationship of quinazolinedione inhibitors of calcium-independent phosphodiesterase.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Animals; Brain; Chemical Phenomena; Chemistry; Male; Mice; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinazolines; Rats; Rolipram; Structure-Activity Relationship

1991
Attenuation of hypoxia-induced increases in ventilation by adenosine antagonists in rhesus monkeys.
    Life sciences, 1995, Volume: 57, Issue:8

    Topics: Adenosine; Animals; Hypoxia; Macaca mulatta; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Quinazolines; Respiration; Rolipram; Triazoles

1995
Anti-inflammatory activity of phosphodiesterase (PDE)-IV inhibitors in acute and chronic models of inflammation.
    Clinical and experimental immunology, 1995, Volume: 100, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Female; Galactosamine; Inflammation; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyrrolidinones; Quinazolines; Rats; Rats, Inbred Lew; Rolipram; Shock, Septic; Tumor Necrosis Factor-alpha

1995
Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro.
    World journal of urology, 1994, Volume: 12, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calmodulin; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydrolysis; In Vitro Techniques; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Purinones; Pyrrolidinones; Quinazolines; Rolipram; Ureter

1994
Effects of CGS 15943, a nonxanthine adenosine antagonist, on behavior in the squirrel monkey.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Animals; Behavior, Animal; Caffeine; Drug Interactions; Drug Synergism; Male; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Quinazolines; Receptors, Purinergic P1; Rolipram; Saimiri; Time Factors; Triazoles

1993
Modulation of TNF alpha and IL-1 beta from endotoxin-stimulated monocytes by selective PDE isozyme inhibitors.
    Agents and actions, 1993, Volume: 39 Spec No

    Topics: Cell Survival; Cells, Cultured; Endotoxins; Humans; Interleukin-1; Isoenzymes; Milrinone; Monocytes; Phosphodiesterase Inhibitors; Purinones; Pyridones; Pyrrolidinones; Quinazolines; Rolipram; Tumor Necrosis Factor-alpha; Vinca Alkaloids

1993
Phosphodiesterase isoenzymes in human ureteral smooth muscle: identification, characterization, and functional effects of various phosphodiesterase inhibitors in vitro.
    Urologia internationalis, 1995, Volume: 55, Issue:4

    Topics: Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydrolysis; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrrolidinones; Quinazolines; Rolipram; Ureter

1995
Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV.
    The Journal of clinical investigation, 1996, Jul-15, Volume: 98, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Actins; Animals; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinases; Glomerulonephritis, Membranoproliferative; Hydralazine; Isoenzymes; Kidney Function Tests; Kidney Glomerulus; Laminin; Male; Phosphodiesterase Inhibitors; Proteinuria; Pyrrolidinones; Quinazolines; Rats; Rats, Wistar; Rolipram; Superoxides

1996
Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors.
    The Biochemical journal, 1996, Sep-01, Volume: 318 ( Pt 2)

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding Sites; Brain; Chromatography, Ion Exchange; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Isoenzymes; Isoproterenol; Kinetics; Macrophages, Peritoneal; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Quinazolines; Rats; Regression Analysis; Rolipram; Stereoisomerism; Thiazoles; Tritium

1996
Cyclic nucleotide phosphodiesterase in human cavernous smooth muscle.
    World journal of urology, 1997, Volume: 15, Issue:1

    Topics: Animals; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Isoenzymes; Male; Muscle, Smooth; Papaverine; Penile Erection; Penis; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrrolidinones; Quinazolines; Rolipram

1997
Inhibitors of cyclic nucleotide phosphodiesterase isozymes block renal tubular cell proliferation induced by folic acid.
    The Journal of laboratory and clinical medicine, 1997, Volume: 130, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cell Division; Cilostazol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Down-Regulation; Folic Acid; Isoenzymes; Kidney Tubules; Male; Phosphodiesterase Inhibitors; Proliferating Cell Nuclear Antigen; Pyrrolidinones; Quinazolines; Quinolones; Rats; Rats, Sprague-Dawley; Rolipram; Signal Transduction; Tetrazoles

1997
[Signal transduction of serotonin release from enterochromaffin cells in mouse ileal crypts].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 112 Suppl 1

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Enterochromaffin Cells; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Norepinephrine; Phosphodiesterase Inhibitors; Prazosin; Pyrrolidinones; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rolipram; Serotonin; Signal Transduction; Yohimbine

1998
Effects of mitogen-activated protein kinase inhibitors or phosphodiesterase inhibitors on interleukin-1-induced cytokines production in synovium-derived cells.
    Immunology letters, 1999, Jun-01, Volume: 68, Issue:2-3

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Calcium-Calmodulin-Dependent Protein Kinases; Cytokines; Dose-Response Relationship, Drug; Humans; Imidazoles; Interleukin-1; Phosphodiesterase Inhibitors; Pyridines; Pyrrolidinones; Quinazolines; Rolipram; Synovial Membrane

1999
Relaxation of human ureteral smooth muscle in vitro by modulation of cyclic nucleotide-dependent pathways.
    Urological research, 2000, Volume: 28, Issue:2

    Topics: Colforsin; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Isoquinolines; Muscle, Smooth; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Platelet Aggregation Inhibitors; Potassium Chloride; Purinones; Quinazolines; Rolipram; Tetrahydroisoquinolines; Ureter; Vasodilator Agents

2000
Syntheses and evaluation of pyrido[2,3-dlpyrimidine-2,4-diones as PDE 4 inhibitors.
    Bioorganic & medicinal chemistry letters, 2001, Mar-12, Volume: 11, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Biological Assay; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Molecular Structure; Phosphodiesterase Inhibitors; Pyrimidines; Quinazolines; Rats; Rolipram

2001
Lixazinone stimulates mitogenesis of Madin-Darby canine kidney cells.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cell Cycle Proteins; Cell Line; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dogs; Epithelial Cells; Gene Expression Regulation, Enzymologic; Kidney; Mitosis; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Quinazolines; Rolipram

2006