Page last updated: 2024-08-21

quinazolines and r 80122

quinazolines has been researched along with r 80122 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ebbert, M; Janssens, WJ; Leidig, A; Meuter, C; Peters, T; Wilffert, B; Wilhelm, D1
de Cheffoy de Courcelles, D; de Loore, K; Freyne, E; Janssen, PA1
D'Aubioul, JA; de Chaffoy de Courcelles, DR; De Clerck, FF; Hermans, CF; Vandeplassche, GM; Wouters, LJ1
Janssen, PA; Reneman, RS; Van de Water, A; Xhonneux, R1
Beck, E; Conrad, C; de Chaffoy de Courcelles, D; Heers, C; Peters, T; Schneider, J; Wilffert, B1
Autschbach, R; Lange, H; Lueerssen, K; Sonntag, H; Stephan, H; Zielmann, S1
Himmel, HM; Li, Q; Ravens, U1
Kazmaier, S; Sonntag, H; Stephan, H1
Eijsman, L; van Wezel, HB; van Zwieten, PA; Visser, CA; Vroom, MB1
Autschbach, R; Becker, B; Lange, H; Mohr, FW; Sonntag, H; Stephan, H1
Herregods, L; Rolly, G; Van Belleghem, Y; Van Nooten, G1
Ferrari, M; Foth, H; Hellige, G; Hering, JP; Schröder, T; Sipinková, I1
Hoeft, A; Kazmaier, S; Sonntag, H; Stephan, H1
de Chaffoy de Courcelles, D; Roevens, P1

Trials

4 trial(s) available for quinazolines and r 80122

ArticleYear
[Hemodynamic effects of new phosphodiesterase inhibitors in patients with coronary heart disease. A comparison between enoximone and R80122].
    Der Anaesthesist, 1995, Volume: 44, Issue:6

    Topics: Adult; Aged; Anesthesia; Blood Pressure; Coronary Disease; Enoximone; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Phosphodiesterase Inhibitors; Quinazolines; Stroke Volume; Vascular Resistance

1995
Hemodynamic effects of the novel selective cAMP-phosphodiesterase III inhibitor R 80122 in anesthetized patients with moderate left ventricular dysfunction before coronary artery bypass grafting.
    Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:3

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Aged; Anesthesia, General; beta-Cyclodextrins; Blood Pressure; Cardiac Output; Cardiotonic Agents; Coronary Artery Bypass; Cyclodextrins; Echocardiography, Transesophageal; Female; Half-Life; Heart Rate; Hemodynamics; Humans; Imidazoles; Infusions, Intravenous; Male; Phosphodiesterase Inhibitors; Premedication; Prospective Studies; Pulmonary Wedge Pressure; Quinazolines; Safety; Solvents; Ventricular Dysfunction, Left

1995
Effects of R80122, a new phosphodiesterase inhibitor, on liver and global haemodynamics in patients undergoing coronary artery bypass surgery.
    Cardiovascular surgery (London, England), 1994, Volume: 2, Issue:6

    Topics: Adult; Aged; Cardiotonic Agents; Coronary Artery Bypass; Coronary Disease; Hemodynamics; Humans; Imidazoles; Intraoperative Care; Liver; Male; Middle Aged; Phosphodiesterase Inhibitors; Quinazolines; Statistics, Nonparametric

1994
Effects of enoximone and R 80122, a new selective phosphodiesterase III inhibitor, on hemodynamics and myocardial energetics in patients with ischemic heart disease.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:6

    Topics: Adult; Aged; Cardiotonic Agents; Catecholamines; Coronary Circulation; Enoximone; Heart; Hemodynamics; Humans; Imidazoles; Lactates; Lactic Acid; Male; Middle Aged; Myocardial Ischemia; Phosphodiesterase Inhibitors; Quinazolines; Vasodilator Agents; Ventricular Function, Left

1994

Other Studies

10 other study(ies) available for quinazolines and r 80122

ArticleYear
In vitro pharmacology of R 80122, a novel phosphodiesterase inhibitor.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5

    Topics: Action Potentials; Animals; Benzimidazoles; Carbachol; Female; Guinea Pigs; Heart Rate; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Norepinephrine; Ouabain; Oxindoles; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridones; Quinazolines; Stimulation, Chemical; Vasodilator Agents

1992
Inhibition of human cardiac cyclic AMP-phosphodiesterases by R 80122, a new selective cyclic AMP-phosphodiesterase III inhibitor: a comparison with other cardiotonic compounds.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Humans; Imidazoles; Kinetics; Phosphodiesterase Inhibitors; Quinazolines; Sarcoplasmic Reticulum

1992
Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:5

    Topics: Analysis of Variance; Animals; Cardiotonic Agents; Dogs; Enoximone; Female; Heart Ventricles; Hemodynamics; Imidazoles; In Vitro Techniques; Isoenzymes; Male; Milrinone; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridones; Quinazolines

1992
Cardiac and hemodynamic effects of intravenous R80122, a new phosphodiesterase III inhibitor, in a canine model of myocardial ischemia and heart failure.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output, Low; Dogs; Female; Heart Rate; Hemodynamics; Imidazoles; Infusions, Intravenous; Male; Milrinone; Myocardial Ischemia; Phosphodiesterase Inhibitors; Pyridones; Quinazolines; Vascular Resistance; Ventricular Function, Left

1992
Cardiac effects of R 79595 and its isomers (R 80122 and R 80123) in an acute heart failure model. A new class of cardiotonic agents with highly selective phosphodiesterase III inhibitory properties.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:5

    Topics: Animals; Cardiac Output; Cardiac Output, Low; Cardiotonic Agents; Female; Guinea Pigs; Heart; Heart Rate; Heart Ventricles; Hexobarbital; Imidazoles; In Vitro Techniques; Isoenzymes; Isoproterenol; Male; Phosphodiesterase Inhibitors; Quinazolines

1992
[Effects of R80122. The influence of a new phosphodiesterase inhibitor on global and intestinal hemodynamics in coronary surgery patients].
    Der Anaesthesist, 1992, Volume: 41, Issue:8

    Topics: Adult; Aged; Cardiotonic Agents; Coronary Artery Bypass; Hemodynamics; Humans; Imidazoles; Liver; Male; Middle Aged; Phosphodiesterase Inhibitors; Quinazolines

1992
Effects of the new phosphodiesterase-III inhibitor R80122 on contractility and calcium current in human cardiac tissue.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Myocardial Contraction; Phosphodiesterase Inhibitors; Quinazolines

1994
Haemodynamic effects of R 80122 immediately after cardiopulmonary bypass; preliminary results.
    Anaesthesia, 1994, Volume: 49, Issue:8

    Topics: Aged; Blood Pressure; Cardiac Output; Cardiopulmonary Bypass; Cardiotonic Agents; Heart Rate; Hemodynamics; Humans; Imidazoles; Middle Aged; Phosphodiesterase Inhibitors; Quinazolines; Vascular Resistance

1994
Peripheral and cardiac effects of a new phosphodiesterase inhibitor in comparison with enoximone.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:8

    Topics: Animals; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Enoximone; Heart; Heart Rate; Hemodynamics; Imidazoles; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Quinazolines; Regional Blood Flow; Sheep; Vascular Resistance; Ventricular Pressure

1994
Cyclic AMP-phosphodiesterase IIIA1 inhibitors decrease cytosolic Ca2+ concentration and increase the Ca2+ content of intracellular storage sites in human platelets.
    Biochemical pharmacology, 1993, Jun-09, Volume: 45, Issue:11

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminoquinolines; Blood Platelets; Calcium; Chlortetracycline; Cytosol; Enoximone; Heart; Homeostasis; Humans; Imidazoles; Milrinone; Phosphodiesterase Inhibitors; Pyridones; Quinazolines

1993