Page last updated: 2024-08-21

quinazolines and quinidine

quinazolines has been researched along with quinidine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kuang, Y; Liu, TP1
Assaraf, YG; Molina, A; Schimke, RT1
Fukuda, K; Kato, T; Kodama, H; Miyoshi, S; Ogawa, S; Tahara, S1
Achira, M; Kume, T; Totsuka, R1
Fuse, E; Kodaira, H; Kusuhara, H; Sugiyama, Y; Ushiki, J1
Fujita, T; Fuse, E; Kodaira, H; Kusuhara, H; Sugiyama, Y; Ushiki, J1
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M1
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M; van de Steeg, E1
Gadotti, VM; Huang, J; Jeong, HR; Jung, DW; Kim, HJ; Kim, JH; Kim, SY; Lee, JY; Lee, KT; Yoon, HB; Zamponi, GW; Zhang, FX1
Annor-Gyamfi, JK; Bunce, RA; Gavin, JT1

Other Studies

10 other study(ies) available for quinazolines and quinidine

ArticleYear
Rate-dependent depression of maximal rate of depolarization in guinea pig papillary muscle action potentials by changrolin.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Female; Guinea Pigs; In Vitro Techniques; Male; Mexiletine; Papillary Muscles; Piperidines; Quinazolines; Quinidine

1990
Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype.
    Journal of the National Cancer Institute, 1989, Feb-15, Volume: 81, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line; Drug Resistance; Female; Genes; Humans; Methotrexate; Ovarian Neoplasms; Phenotype; Quinazolines; Quinidine; RNA, Messenger; Trimetrexate; Tumor Cells, Cultured; Verapamil

1989
Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.
    Journal of the American College of Cardiology, 2001, Nov-01, Volume: 38, Issue:5

    Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channels, L-Type; Cells, Cultured; Cytochalasin D; Drug Evaluation, Preclinical; ErbB Receptors; Focal Adhesion Kinase 2; Mitogen-Activated Protein Kinases; Myocardium; Phosphorylation; Piperidines; Potassium Channel Blockers; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Quinidine; Rats; Rats, Wistar; Tetraethylammonium; Time Factors; Tyrphostins

2001
Differences in pharmacokinetics and hepatobiliary transport of a novel anti-inflammatory agent between normal and adjuvant arthritis rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:12

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Area Under Curve; Arthritis, Experimental; Biological Transport; Caco-2 Cells; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Hydrazines; Injections, Intravenous; Liver; Models, Chemical; Quinazolines; Quinidine; Rats; Rats, Inbred Lew; Time Factors

2002
Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:3

    Topics: Algorithms; Animals; Antimalarials; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Dantrolene; Erlotinib Hydrochloride; Flavonoids; Kinetics; Male; Mice; Mice, Knockout; Mitoxantrone; Muscle Relaxants, Central; Neoplasm Proteins; Piperidines; Protein Kinase Inhibitors; Quinazolines; Quinidine; Testis; Tissue Distribution; Xenobiotics

2010
Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:3

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Biomarkers; Blood-Brain Barrier; Brain; Dogs; Erlotinib Hydrochloride; Female; Humans; Male; Mice; Mice, Knockout; Neoplasm Proteins; Protein Binding; Quinazolines; Quinidine; Rats

2011
Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; In Vitro Techniques; Intestinal Mucosa; Isoquinolines; Ketoconazole; Male; Quinazolines; Quinidine; Rats, Wistar; Rhodamine 123; Verapamil

2015
The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 40

    Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colon; Cyclosporins; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ileum; In Vitro Techniques; Isoquinolines; Jejunum; Ketoconazole; Male; Middle Aged; Quinazolines; Quinidine; Verapamil

2017
Synthesis and biological evaluation of fluoro-substituted 3,4-dihydroquinazoline derivatives for cytotoxic and analgesic effects.
    Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

    Topics: A549 Cells; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cell Survival; Drug Stability; Fluorine; HEK293 Cells; Humans; Inhibitory Concentration 50; Microsomes, Liver; Patch-Clamp Techniques; Quinazolines; Quinidine; Rats

2017
Quinazolin-4(3
    Molecules (Basel, Switzerland), 2018, Nov-09, Volume: 23, Issue:11

    Topics: Amides; Molecular Structure; Quinazolines; Quinidine

2018