quinazolines has been researched along with phosphotyrosine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 19 (67.86) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, PB; Contessa, JN; Dent, P; Kavanagh, BD; Mikkelsen, RB; Rorrer, WK; Schmidt-Ullrich, RK; Todd, DG; Valerie, K | 1 |
| Breu, J; Muchnicki, L; Slack, BE; Wurtman, RJ | 1 |
| Eguchi, S; Hirata, Y; Inagami, T; Iwasaki, H; Kawakatsu, H; Marumo, F; Matsumoto, T; Motley, ED; Numaguchi, K; Owada, KM; Utsunomiya, H; Yamakawa, T | 1 |
| Farrell, GC; Zhang, BH | 1 |
| Arnold, LD; Baker, DA; Barbacci, EG; Davis, JA; Doty, JL; Iwata, KK; Morin, MJ; Moyer, JD; Pollack, VA; Pustilnik, LR; Savage, DM; Sloan, DE; Smolarek, TA; Tsaparikos, KE; Vaidya, MP | 1 |
| Minneman, KP; Zhong, H | 1 |
| Braun, L; Chase, CC; Frew, T; Hurley, DJ; Rowland, RR; Shaw, AM | 1 |
| Barrett, KE; Calandrella, SO; Keely, SJ | 1 |
| Bonner, JC; Wang, YZ | 1 |
| Jue, SF; Maurer, RA; Wang, YH | 1 |
| Berk, BC; Chen, K; Keaney, JF; Vita, JA | 1 |
| Chen, MC; Kui, R; Perez Salazar, E; Rozengurt, E; Soll, AH; Solomon, TE | 1 |
| Barrett, KE; McCole, DF; Uribe, JM | 1 |
| Chen, X; Pennock, S; Wang, Y; Wang, Z | 1 |
| Fenyo, D; Gibson, N; Griffin, G; Haley, JD; Hunt, T; Iwata, K; Petti, F; Settinari, T; Thelemann, A | 1 |
| Delamere, NA; Tamiya, S | 1 |
| Kitayama, J; Mori, K; Nagawa, H; Shida, D; Watanabe, T; Yamashita, H | 1 |
| Dessypris, EN; Kanamori, D; McCarty, JM; Melone, PD; Simanis, JP; Warshamana-Greene, GS | 1 |
| Furukawa, M; Goya, S; Greene, MI; Kawase, I; Kijima, T; Kumagai, T; Matsuoka, H; Nagatomo, I; Osaki, T; Tachibana, I; Takahashi, R; Takeda, Y; Yamadori, T; Yoneda, T; Yoshida, M; Yoshimura, M | 1 |
| Ang, BK; Chen, Y; Choong, LY; Druker, BJ; Hew, CL; Li, B; Lim, S; Lim, YP; Lin, Q; Low, TY; Ray, RS; Sze, NS; Tan, YL; Toy, W; Wong, CH | 1 |
| Bartholomeusz, C; Hortobagyi, GN; Kurisu, K; Sudo, T; Ueno, NT; Yamasaki, F; Zhang, D | 1 |
| Barry, ST; Copley, C; James, NH; Jürgensmeier, JM; Kendrew, J; Oakley, I; Smith, NR; Wainwright, A; Wedge, SR; Womersley, LM | 1 |
| Chen, CS; Chen, Y; Choong, LY; Druker, BJ; Hande, MP; Lim, S; Lim, YP; Loh, MC; Man, X; Pan, M; Poonepalli, A; Salto-Tellez, M; Shah, N; Tan, PH; Toy, W; Wong, CY | 1 |
| Comb, MJ; Guo, A; Gygi, SP; Innocenti, G; Kornhauser, J; Lee, KA; MacNeill, J; Mitchell, J; Nardone, J; Polakiewicz, RD; Possemato, A; Rikova, K; Rush, J; Stokes, MP; Villén, J; Wang, Y; Wetzel, R | 1 |
| Boronina, T; Cole, PA; Cole, RN; Kavran, JM; Leahy, DJ; Longo, PA; Qiu, C; Tarrant, MK | 1 |
| Berna, MJ; Chan, D; Giaccone, G; Jensen, RT; Mantey, S; Moody, TW; Ridnour, L; Sancho, V; Wink, DA | 1 |
| Ai, M; He, L; Jin, Y; Long, Y; Qin, L; Song, Q; Tian, W; You, S; Yu, Q; Zhou, Z | 1 |
| Awasthi, S; Bansal, M; Belkina, N; Biswas, R; Califano, A; Chaerkady, R; Charles Jacob, HK; Cultraro, CM; Gao, S; Guha, U; Kashyap, MK; Kirkali, G; Maity, T; Marimuthu, A; Pandey, A; Pitts, S; Singh, S; Venugopalan, A; Zhang, X | 1 |
28 other study(ies) available for quinazolines and phosphotyrosine
| Article | Year |
|---|---|
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation.
Topics: Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Division; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Nitriles; Phospholipase C gamma; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Quinazolines; Radiation, Ionizing; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins | 1997 |
Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of protein kinase C.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Androstadienes; Aspartic Acid Endopeptidases; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Inositol; Inositol Phosphates; Maleimides; Nitriles; Phosphatidylinositols; Phosphotyrosine; Protein Kinase C; Quinazolines; Tumor Cells, Cultured; Tyrphostins; Wortmannin | 1997 |
Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta, Thoracic; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; GRB2 Adaptor Protein; Muscle, Smooth, Vascular; Nitriles; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proteins; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Rats; Rats, Sprague-Dawley; src Homology Domains; Tyrphostins | 1998 |
Chronic ethanol consumption disrupts complexation between EGF receptor and phospholipase C-gamma1: relevance to impaired hepatocyte proliferation.
Topics: Animals; Calcium Signaling; Cell Division; Cells, Cultured; Cytoskeleton; Cytosol; DNA; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Ethanol; Isoenzymes; Liver; Male; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein Binding; Quinazolines; Rats; Rats, Wistar; Type C Phospholipases; Tyrphostins | 1999 |
Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: dynamics of receptor inhibition in situ and antitumor effects in athymic mice.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Phosphorylation; Phosphotyrosine; Polypharmacy; Quinazolines; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured; Tyrosine | 1999 |
Activation of tyrosine kinases by alpha1A-adrenergic and growth factor receptors in transfected PC12 cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Differentiation; Cytoskeletal Proteins; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; GRB2 Adaptor Protein; GTP-Binding Proteins; Mitogen-Activated Protein Kinases; Norepinephrine; Paxillin; PC12 Cells; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Growth Factor; Receptors, Nerve Growth Factor; Signal Transduction; Transfection; Tyrphostins | 1999 |
A role for bovine herpesvirus 1 (BHV-1) glycoprotein E (gE) tyrosine phosphorylation in replication of BHV-1 wild-type virus but not BHV-1 gE deletion mutant virus.
Topics: Animals; Capsid; Cell Line; Dogs; Gene Deletion; Genistein; Herpesvirus 1, Bovine; Mutation; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Quinazolines; Tyrphostins; Viral Envelope Proteins; Viral Proteins; Virus Replication | 2000 |
Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca2+, PYK-2, and p60(src).
Topics: Calcium; Carbachol; Cell Line; Chlorides; Colon; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; Fluphenazine; Focal Adhesion Kinase 2; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Signal Transduction; Thapsigargin; Time Factors; Transcriptional Activation; Tyrphostins | 2000 |
Mechanism of extracellular signal-regulated kinase (ERK)-1 and ERK-2 activation by vanadium pentoxide in rat pulmonary myofibroblasts.
Topics: Acetylcysteine; Animals; Asthma; Bronchitis; Carbon; Coal Ash; Colforsin; Enzyme Activation; ErbB Receptors; Fibroblasts; Flavonoids; Intracellular Signaling Peptides and Proteins; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Particulate Matter; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Quinazolines; Rats; Titanium; Tyrphostins; Vanadium Compounds | 2000 |
Thyrotropin-releasing hormone stimulates phosphorylation of the epidermal growth factor receptor in GH3 pituitary cells.
Topics: Animals; Enzyme Inhibitors; ErbB Receptors; Genes, Reporter; Indoles; Luciferases; Maleimides; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Pituitary Neoplasms; Protein Kinase C; Quinazolines; Rats; Recombinant Proteins; Thyrotropin-Releasing Hormone; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tyrphostins | 2000 |
c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Aorta; Benzoquinones; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Genistein; GRB2 Adaptor Protein; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Pyrimidines; Quinazolines; Quinones; Rifabutin; Swine; Transcriptional Activation; Tyrphostins | 2001 |
Secretin regulates paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Electric Impedance; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; ErbB Receptors; Gastric Mucosa; Mannitol; Parietal Cells, Gastric; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinazolines; Secretin; src-Family Kinases; Tyrphostins | 2002 |
Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.
Topics: Antibodies; Blotting, Western; Carbachol; Cell Line; Cell Membrane; Chlorides; Colon; Enzyme Inhibitors; ErbB Receptors; Humans; Immunosorbent Techniques; Interferon-gamma; Intestinal Mucosa; Kinetics; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; src-Family Kinases; Transforming Growth Factor alpha; Tyrphostins | 2002 |
Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor.
Topics: Animals; Breast Neoplasms; Cell Line; Dogs; Endosomes; ErbB Receptors; Fluorescent Antibody Technique, Indirect; Humans; Kidney; Membrane Proteins; Mice; Monensin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Quinazolines; Signal Transduction; Tumor Cells, Cultured; Tyrphostins | 2002 |
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Chromatography, Affinity; Chromatography, Liquid; Enzyme Activation; ErbB Receptors; Erlotinib Hydrochloride; Head and Neck Neoplasms; Humans; Immunoblotting; Isotopes; Mass Spectrometry; Models, Biological; Peptide Mapping; Phosphorylation; Phosphotyrosine; Proteins; Quinazolines; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; src-Family Kinases | 2005 |
Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.
Topics: Animals; Blotting, Western; Cell Proliferation; Enzyme Inhibitors; Epithelium; Lens, Crystalline; Organ Culture Techniques; Phosphorylation; Phosphotyrosine; Proliferating Cell Nuclear Antigen; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; src-Family Kinases; Swine; Tyrosine; Tyrphostins | 2005 |
Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.
Topics: Cell Line, Tumor; Chemotaxis; Colonic Neoplasms; Dipeptides; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Humans; Interleukin-8; Lysophospholipids; Phosphorylation; Phosphotyrosine; Protease Inhibitors; Quinazolines; Transcriptional Activation; Tyrphostins | 2006 |
A preliminary investigation into the action of anagrelide: thrombopoietin-c-Mpl receptor interactions.
Topics: Antigens, CD34; Cell Differentiation; Cell Line; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Interleukin-3; Models, Biological; Phosphotyrosine; Platelet Aggregation Inhibitors; Platelet Membrane Glycoprotein IIb; Ploidies; Proto-Oncogene Proteins; Quinazolines; Receptors, Cytokine; Receptors, Thrombopoietin; Thrombopoietin | 2006 |
Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis.
Topics: Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Drug Resistance, Neoplasm; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Ligands; Mice; Mutation; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-cbl; Quinazolines; Sequence Deletion; Tyrosine; Ubiquitin | 2007 |
Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells.
Topics: Amino Acid Sequence; Cell Line, Tumor; Epidermal Growth Factor; Gefitinib; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microtubule-Associated Proteins; Molecular Sequence Data; Neoplasms; Phosphoproteins; Phosphotyrosine; Proteomics; Quinazolines; Serine Endopeptidases; Signal Transduction; Tandem Mass Spectrometry | 2007 |
Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Female; G1 Phase; Genes, Dominant; Humans; Phosphorylation; Phosphotyrosine; Protein Transport; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Transfection | 2007 |
Acute pharmacodynamic and antivascular effects of the vascular endothelial growth factor signaling inhibitor AZD2171 in Calu-6 human lung tumor xenografts.
Topics: Animals; Antibodies, Neoplasm; Antibodies, Phospho-Specific; Antineoplastic Agents; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Neovascularization, Pathologic; Phosphorylation; Phosphotyrosine; Quinazolines; Reproducibility of Results; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2007 |
Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics.
Topics: Animals; Asian People; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Drug Delivery Systems; Drug Resistance, Neoplasm; Enzyme Activation; ErbB Receptors; Female; Gefitinib; Gene Dosage; Humans; Mice; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotyrosine; Proteomics; Quinazolines; Reproducibility of Results | 2007 |
Signaling networks assembled by oncogenic EGFR and c-Met.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Models, Biological; Neoplasm Metastasis; Phosphotyrosine; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proteomics; Proto-Oncogene Proteins c-met; Quinazolines; Signal Transduction | 2008 |
In vitro enzymatic characterization of near full length EGFR in activated and inhibited states.
Topics: Amino Acid Sequence; Cell Line; Enzyme Activation; ErbB Receptors; Erlotinib Hydrochloride; Humans; Kinetics; Lapatinib; Molecular Sequence Data; Mutant Proteins; Phosphopeptides; Phosphorylation; Phosphotyrosine; Quinazolines; Time Factors | 2009 |
Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.
Topics: Acetylcysteine; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Humans; Neurokinin B; Phosphorylation; Phosphotyrosine; Quinazolines; Reactive Oxygen Species; Receptors, Bombesin; Transcriptional Activation; Tumor Cells, Cultured | 2010 |
A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Screening Assays, Antitumor; Drug Synergism; G2 Phase; Humans; Microtubules; Mitosis; Phosphorylation; Phosphotyrosine; Quinazolines; Spindle Apparatus; Tubulin | 2010 |
Quantitative Tyrosine Phosphoproteomics of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-treated Lung Adenocarcinoma Cells Reveals Potential Novel Biomarkers of Therapeutic Response.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Afatinib; Biomarkers, Tumor; Cell Line, Tumor; Cluster Analysis; ErbB Receptors; Erlotinib Hydrochloride; Humans; Isotope Labeling; Lung Neoplasms; Mass Spectrometry; Mutation; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Proteomics; Quinazolines; Reproducibility of Results; Signal Transduction; Tyrosine | 2017 |