quinazolines has been researched along with phenylephrine in 79 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (46.84) | 18.7374 |
| 1990's | 24 (30.38) | 18.2507 |
| 2000's | 15 (18.99) | 29.6817 |
| 2010's | 2 (2.53) | 24.3611 |
| 2020's | 1 (1.27) | 2.80 |
| Authors | Studies |
|---|---|
| Chasin, M; Greenslade, FC; Madison, SM; Scott, CK; Tobia, AJ | 1 |
| Cavero, I; Lefèvre, F; Roach, AG | 1 |
| Chen, CF; Chiou, WF; Chou, CJ; Shum, AY | 1 |
| Gilbey, MP; Marks, SA | 1 |
| Hayashi, Y; Ikeda, K; Ohnishi, H; Watanabe, K | 2 |
| Chiba, S; Matsuura, M; Zenda, H | 1 |
| Miyamoto, Y; Nakasone, J; Noguchi, K; Sakanashi, M | 1 |
| Buckingham, JC; Dashwood, MR; Ginsburg, J; Leposavic, G | 1 |
| Chiba, S; Nakane, T | 1 |
| Akimoto, Y; Fujiwara, M; Kurahashi, K; Sono, K | 1 |
| Akima, M; Imagawa, J; Sakai, K | 1 |
| Shebuski, RJ; Zimmerman, BG | 1 |
| Sugimoto, T; Uchida, Y | 1 |
| Imagawa, J; Nabata, H; Sakai, K | 1 |
| Ikegaki, I; Matsuzawa, M; Okabayashi, H; Suga, K; Takahashi, H; Yoshimura, M | 1 |
| Orimo, H; Ouchi, Y; Watanabe, M | 1 |
| Aono, J; Sakai, K | 1 |
| Moulds, RF; Stevens, MJ | 1 |
| Deering, AH; Harron, DW; Riddell, JG; Shanks, RG | 1 |
| Ali, FK; Kwa, HY; Timmermans, PB; van Zwieten, PA | 1 |
| Osnes, JB; Oye, I; Skomedal, T | 1 |
| Hassanein, KM; Hurwitz, A; Pitterman, AB; Rollins, DE; Shen, DD | 1 |
| Constantine, JW; Hess, HJ | 1 |
| Hattori, Y; Kanno, M | 1 |
| Elliott, HL; Meredith, PA; Reid, JL; Vincent, J | 1 |
| Ludvig, N; Vizi, ES | 1 |
| Ishikawa, S | 1 |
| Cavero, I | 1 |
| Hernandez, J; Prichard, BN; Saxton, CA; Singleton, W | 1 |
| Langer, SZ; Shepperson, NB | 1 |
| McCarthy, L; McMahon, KK; Schimmel, RJ | 1 |
| Lindström, B; Seideman, P; von Bahr, C | 1 |
| Deth, RC; Lynch, CJ; Steer, ML | 1 |
| Godfraind, T; Miller, RC; Socrates Lima, J | 1 |
| Heilman, RD; Lee, JY; Radzialowski, FM; Walsh, GM | 1 |
| Guder, WG; Lefrank, S; Wirthensohn, G | 1 |
| Constantine, JW; Lebel, W; Weeks, R | 1 |
| Aramendía, P; Eisenschlos, CD; Márquez, MT | 1 |
| Pipili, E; Poyser, NL | 1 |
| Macho, P; Vatner, SF | 2 |
| Adenekan, OO; Tayo, FM | 1 |
| Karasawa, A; Marumo, H; Shuto, K | 1 |
| Chen, SY; Chern, JW; Tao, PL; Tseng, CJ; Yen, MH | 1 |
| Carter, AJ; Greengrass, PM; Kenny, BA; Naylor, AM; Read, AM; Wyllie, MG | 1 |
| Chen, CF; Chiou, WF; Chou, CJ; Liao, JF; Sham, AY | 1 |
| Kuwayama, Y; Matsugi, T; Nishimura, K; Shirasawa, E; Sun, N | 1 |
| Chiba, S; Fujiwara, T | 1 |
| Gautier, E; Hicks, PE; Langer, SZ; Lechaire, J; Lefèvre-Borg, F; Manoury, P; O'Connor, SE; Pierre, F; Pimoule, C; Schoemaker, H | 1 |
| Iwai, M; Shimazu, T | 1 |
| Chern, JW; Lee, YM; Peng, IH; Sheu, JR; Yen, MH | 1 |
| Chalmers, DH; Kenny, BA; Miller, AM; Naylor, AM; O'Connell, J; Williamson, IJ | 1 |
| Auguet, M; Chabrier, PE; Guilmard, C | 1 |
| Nasa, Y; Takeo, S; Yabe, K | 1 |
| Chen, CF; Chiou, WF; Liao, JF; Shum, AY | 1 |
| Deng, XF; Mulay, S; Varma, DR | 1 |
| Angel, I; Lluel, P; Martin, DJ; Pouyet, T; Rauch-Desanti, C | 1 |
| Saxena, PR; Stam, WB; Van der Graaf, PH | 1 |
| Hayakawa, H; Hirata, Y; Kakoki, M; Kikuchi, K; Nagano, T; Nagata, D; Nishimatsu, H; Omata, M; Suzuki, E; Suzuki, Y | 1 |
| Hieble, JP; Kolpak, DC; Leonardi, A; McCafferty, GP; Ruffolo, RR; Testa, R | 1 |
| Chern, JW; Ding, YA; Lee, SF; Tsai, LM; Yang, JM; Yang, SN | 1 |
| Endo, T; Hamaue, N; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Parvez, H | 1 |
| Kawai, T; Koshimizu, T; Nasa, Y; Oshikawa, S; Shinoura, H; Sunada, S; Takeo, S; Tanoue, A; Tsujimoto, G | 1 |
| Dartt, DA; Hodges, RR; Tepavcevic, V; Zoukhri, D | 1 |
| Fung, KY; Hertz, L; Peng, L; Prévot, V; Yu, AC | 1 |
| Akaishi, T; Hara, H; Ishida, N; Kashiwagi, K; Matsugi, T; Takagi, Y | 1 |
| Avellar, MC; Hamamura, M; Mendes, FR; Porto, CS; Queiróz, DB | 1 |
| Chalothorn, D; Faber, JE; Jackson, LF; Lee, DC; Zhang, H | 1 |
| Araie, M; Asai, Y; Hara, H; Ichikawa, M; Ishii, K; Okada, Y | 1 |
| Fernandez-Patron, C; Hao, L; Nishimura, T; Wo, H | 1 |
| Nagano, M; Osada, Y; Yamaguchi, T | 1 |
| Chapple, CR; Michel, MC | 1 |
| Noguchi, Y; Ohtake, A; Sasamata, M; Suzuki, M | 1 |
| Chang, DF; Lluel, P; Palea, S; Regnier, A; Rekik, M | 1 |
| Astulla, A; Ekasari, W; Hirasawa, Y; Matsuno, Y; Morita, H; Widyawaruyanti, A; Zaima, K; Zaini, NC | 1 |
| Babaeva, E; Gradinaru, I; Kleine-Brueggeney, M; Oganesian, A; Schwinn, DA | 1 |
| Ait-Aissa, K; Ali, M; Kassan, M; Matrougui, K; Trebak, M | 1 |
| Alsufyani, HA; Docherty, JR; McCormick, PA | 1 |
5 trial(s) available for quinazolines and phenylephrine
| Article | Year |
|---|---|
Effect of acute and chronic oral administration of alfuzosin on baroreflex function and tremor in man.
Topics: Adult; Antihypertensive Agents; Heart Rate; Humans; Male; Phenylephrine; Pressoreceptors; Quinazolines; Reflex; Tremor | 1988 |
Alpha adrenoceptor blockade with oral prazosin.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Cold Temperature; Dose-Response Relationship, Drug; Female; Humans; Male; Phenylephrine; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Doxazosin, an alpha 1-adrenoceptor antagonist: pharmacokinetics and concentration-effect relationships in man.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; Half-Life; Heart Rate; Humans; Kinetics; Male; Phenylephrine; Prazosin; Quinazolines | 1983 |
Postjunctional selectivity of alpha-blockade with prazosin, trimazosin, and UK-33,274 in man.
Topics: Adrenergic alpha-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Doxazosin; Heart Rate; Humans; Male; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinazolines | 1982 |
Comparison of the cardiovascular effects of tamsulosin oral controlled absorption system (OCAS) and alfuzosin prolonged release (XL).
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Age Factors; Aged; Blood Pressure; Cross-Over Studies; Delayed-Action Preparations; Dizziness; Humans; Male; Middle Aged; Phenylephrine; Quinazolines; Sulfonamides; Tamsulosin; Vascular Resistance | 2006 |
74 other study(ies) available for quinazolines and phenylephrine
| Article | Year |
|---|---|
Interaction of prazosin with alpha-adrenergic receptors--in vitro binding and in vivo antagonism.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Haplorhini; In Vitro Techniques; Phentolamine; Phenylephrine; Phosphodiesterase Inhibitors; Prazosin; Quinazolines; Rabbits; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vagotomy | 1979 |
Effects of prazosin and phentolamine on cardiac presynaptic alpha-adrenoceptors in the cat, dog and rat.
Topics: Animals; Cats; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Female; Heart Rate; Imidazoles; Male; Phentolamine; Phenylephrine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1978 |
The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: mode of action.
Topics: Animals; Calcium; Calcium Channels; Calcium Chloride; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Plant Extracts; Potassium Channels; Quinazolines; Rats; Rats, Sprague-Dawley; Tetraethylammonium Compounds; Vasodilator Agents | 1992 |
Effect on cardiac sympathetic nerve activity of phenylephrine microinjected into the cat intermediolateral cell column.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Female; Heart; Phenylephrine; Quinazolines; Receptors, Adrenergic, alpha; Spinal Cord; Sympathetic Nervous System | 1992 |
[Effect of moxisylyte on the lower urinary tracts (1). Effect on the isolated rabbit urethra and bladder].
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Moxisylyte; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Prazosin; Quinazolines; Rabbits; Urethra; Urinary Bladder | 1991 |
[Effect of moxisylyte on the lower urinary tracts (2). Effect on the urethra in anesthetized dogs].
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Moxisylyte; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phentolamine; Phenylephrine; Prazosin; Quinazolines; Urethra; Yohimbine | 1991 |
Pharmacologic analysis of 7-O-ethyl-fangchinoline-induced vasodilation properties in isolated perfused common carotid arteries of Wistar Kyoto rats and spontaneously hypertensive rats.
Topics: Alkaloids; Animals; Atropine; Benzylisoquinolines; Carotid Arteries; Diltiazem; In Vitro Techniques; Isoproterenol; Male; Phenylephrine; Propranolol; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasodilation; Vasodilator Agents | 1991 |
Pharmacological properties of 5-[(6,7,8-trimethoxy-4-quinazolinyl) amino]-1-pentanyl nitrate maleate in cardiovascular system.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiovascular Agents; Cardiovascular System; Coronary Vessels; Dogs; Endothelium, Vascular; Female; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitro Compounds; Nitroglycerin; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Regional Blood Flow; Vascular Resistance | 1991 |
Peripubertal changes in the nature of the GnRH response to alpha-adrenoceptor stimulation in vitro and their modulation by testosterone.
Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Hypothalamus; In Vitro Techniques; Luteinizing Hormone; Male; Orchiectomy; Phenylephrine; Pituitary Hormone-Releasing Hormones; Propranolol; Quinazolines; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sexual Maturation; Testosterone | 1990 |
Postjunctional alpha-adrenoceptor subtypes in isolated and perfused canine epicardial coronary arteries.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Coronary Vessels; Dogs; Female; Imidazoles; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Quinazolines; Receptors, Adrenergic, alpha; Vasoconstriction; Vasodilation; Xylazine | 1987 |
Effects of specific alpha-adrenoceptive agents on extraneuronal uptake (uptake2) of isoproterenol in perfused rat heart.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Guanabenz; Isoproterenol; Male; Methoxamine; Myocardium; Neurons; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Sulfonamides; Tropolone | 1989 |
In vivo experiments for the evaluation of alpha 1-adrenoceptor antagonistic effects of SGB-1534 on canine urethra.
Topics: Adrenergic alpha-Antagonists; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hypogastric Plexus; Phenylephrine; Prazosin; Quinazolines; Urethra | 1989 |
Suppression of reflex tachycardia by central administration of the alpha-1 adrenoceptor antagonists urapidil and prazosin in anesthetized dogs.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Brain; Dogs; Female; Heart Rate; Indoramin; Male; Phenylephrine; Piperazines; Prazosin; Pressoreceptors; Quinazolines; Reflex; Vascular Resistance | 1985 |
[Cardiovascular effect of a novel substance, 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl] ethyl]-2,4 (1H, 3H)-quinazolinedione monohydrochloride (SGB 1534)].
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Dogs; Heart Rate; Myocardial Contraction; Phenylephrine; Quinazolines; Vascular Resistance | 1985 |
Comparison of cardiovascular effects of SGB-1534 and prazosin, selective alpha 1-adrenoceptor antagonists, in anesthetized dogs.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; Phenylephrine; Prazosin; Quinazolines; Renal Circulation; Vascular Resistance; Vasoconstriction | 1987 |
Sympatholytic effects of the intravenously injected alpha 1-adrenergic blocker, bunazosin, in anaesthetized rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Denervation; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Phentolamine; Phenylephrine; Pressoreceptors; Quinazolines; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1987 |
Alpha-blocker, bunazosinhydrochloride decreases cytosolic Ca++ of cultured rat aortic smooth muscle cells.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; Cells, Cultured; Cytosol; Kinetics; Muscle, Smooth, Vascular; Phenylephrine; Quinazolines; Rats; Rats, Inbred Strains | 1988 |
Investigations into the mechanism of the antihypertensive effect of SGB-1534, a novel alpha 1-adrenoceptor antagonist, in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Factors determining alpha-adrenoceptor-mediated responses of human digital arteries and metacarpal veins.
Topics: Desipramine; Dose-Response Relationship, Drug; Fingers; Humans; Hydrocortisone; Metacarpus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Prazosin and its analogues UK-18,596 and UK-33,274: a comparative study on cardiovascular effects and alpha-adrenoceptor blocking activities.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Clonidine; Doxazosin; Heart Rate; Hemodynamics; Hexobarbital; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Quinazolines; Rats | 1980 |
Competitive blockade of alpha-adrenergic receptors in rat heart by prazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Heart; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Phentolamine; Phenylephrine; Prazosin; Propranolol; Quinazolines; Rats | 1980 |
The cardiovascular effects of trimazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Hindlimb; In Vitro Techniques; Male; Nictitating Membrane; Norepinephrine; Phenoxybenzamine; Phenylephrine; Piperazines; Propranolol; Quinazolines; Rabbits; Rats; Vasoconstriction | 1981 |
Effect of E-643 on alpha-adrenoceptor-mediated inotropic responses to phenylephrine in the left atria of guinea pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Guinea Pigs; Heart Atria; In Vitro Techniques; Myocardial Contraction; Phenylephrine; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sotalol; Stimulation, Chemical | 1982 |
(-)-Amidephrine, a selective agonist for alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Electric Stimulation; Ethanolamines; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Vas Deferens | 1983 |
Effects of a new alpha 1-adrenoceptor blocking agent, 3-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-(1H,3H)-quinazoline-2, 4-dione monohydrochloride (SGB1534), on electrical and mechanical properties of guinea-pig mesenteric artery.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinazolines; Serotonin; Synaptic Transmission | 1984 |
Effects of prazosin on reflex changes in heart rate evoked by vasopressor and vasodepressor stimuli in conscious rabbits.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Female; Heart Rate; Male; Phenylephrine; Prazosin; Quinazolines; Rabbits; Reflex | 1982 |
Postjunctional alpha 1-adrenoceptors: preferential innervation of alpha 1-adrenoceptors and the role of neuronal uptake.
Topics: Animals; Blood Pressure; Cats; Cocaine; Muscle, Smooth, Vascular; Neurons; Phenylephrine; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Regional Blood Flow; Spleen; Time Factors | 1982 |
Alpha 1-adrenergic stimulation of hamster brown adipocyte respiration.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue, Brown; Animals; Clonidine; Cricetinae; Isoproterenol; Kinetics; Male; Mesocricetus; Methoxamine; Norepinephrine; Oxygen Consumption; Phenylephrine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic, alpha | 1983 |
Alpha-receptor function changes after the first dose of prazosin.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypotension, Orthostatic; Male; Phenylephrine; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Time Factors | 1982 |
Simultaneous loss and reappearance of alpha 1-adrenergic responses and [3H]prazosin binding sites in rat liver after irreversible blockade by phenoxybenzamine.
Topics: Animals; Calcium; Female; Glucose; Kinetics; Liver; Phenoxybenzamine; Phenylephrine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
The selectivity of prazosin in rat aorta.
Topics: Animals; Aorta; Blood Vessels; Calcium; Cinnarizine; Flunarizine; In Vitro Techniques; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1983 |
Differential blocking effects of prazosin and yohimbine on vasopressor responses to sympathetic nerve stimulation and intravenous norepinephrine in the pithed rat.
Topics: Animals; Blood Pressure; Clonidine; Electric Stimulation; Male; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1984 |
Phospholipid metabolism in rat kidney cortical tubules. II. Effects of hormones on 32P incorporation.
Topics: Angiotensin II; Animals; Kidney Cortex; Kidney Tubules; Kinetics; Male; Parathyroid Hormone; Phenylephrine; Phospholipids; Phosphorus Radioisotopes; Prazosin; Quinazolines; Rats; Rats, Inbred Strains | 1984 |
Effects of trimazosin and prazosin on blood pressure and on pressor responses to phenylephrine in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diazoxide; Dose-Response Relationship, Drug; Heart Rate; Male; Phenylephrine; Piperazines; Prazosin; Pressoreceptors; Quinazolines; Rats; Solvents | 1983 |
Antagonism and supersensitivity to phenylephrine-induced chronotropic responses.
Topics: Animals; Calcium; Female; Heart Rate; In Vitro Techniques; Myocardium; Papaverine; Phentolamine; Phenylephrine; Prazosin; Quinazolines; Rats | 1983 |
Differential effects of prazosin and rauwolsin on the release of prostaglandins I2 and E2 from the perfused mesenteric arterial bed of the rabbit following nerve stimulation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Electric Stimulation; Epoprostenol; Indomethacin; Male; Mesenteric Arteries; Norepinephrine; Phenylephrine; Prazosin; Prostaglandins; Prostaglandins E; Quinazolines; Rabbits; Vasoconstriction; Yohimbine | 1982 |
Effects of prazosin on coronary and left ventricular dynamics in conscious dogs.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Heart Rate; Heart Ventricles; Myocardial Contraction; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinazolines; Reserpine; Vascular Resistance | 1982 |
Analysis of the antagonism by prazosin of noradrenaline and phenylephrine induced contractions of the rat anococcygeus muscle.
Topics: Anal Canal; Animals; Coccyx; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscles; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains | 1982 |
Effects of prazosin, phentolamine, and yohimbine on the pressor responses induced by noradrenaline, phenylephrine, and bilateral carotid artery occlusion in anaesthetized dogs.
Topics: Animals; Blood Pressure; Carotid Artery Diseases; Dogs; Female; Male; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Quinazolines; Yohimbine | 1982 |
Effects and mechanism of action of trimazosin on coronary and left ventricular dynamics in conscious dogs.
Topics: Animals; Blood Pressure; Carotid Arteries; Coronary Circulation; Dogs; Heart; Heart Rate; Myocardial Contraction; Norepinephrine; Phenylephrine; Piperazines; Pressure; Propranolol; Quinazolines; Reserpine; Vasodilator Agents | 1981 |
Antihypertensive effects of AT-112, a newly synthesized quinazoline derivative, in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Clonidine; Endothelium, Vascular; Female; Hypertension; Male; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Serotonin; Vasodilation | 1995 |
Effect of alpha 1 adrenoceptor antagonists on prostatic pressure and blood pressure in the anesthetized dog.
Topics: Adrenergic alpha-Antagonists; Affinity Labels; Anesthesia, Endotracheal; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Doxazosin; Male; Models, Biological; Phenylephrine; Piperazines; Prazosin; Pressure; Prostate; Quinazolines; Sulfonamides; Tamsulosin | 1994 |
The mechanism of the vasodilator effect of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa.
Topics: Acetylcholine; Alkaloids; Animals; Arginine; Atropine; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indole Alkaloids; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Phenylephrine; Quinazolines; Rats; Rats, Sprague-Dawley; Triprolidine; Vasodilation; Yohimbine | 1994 |
Selective suppression by bunazosin of alpha-adrenergic agonist evoked elevation of intraocular pressure in sympathectomized rabbit eyes.
Topics: Adrenergic alpha-Antagonists; Animals; Ganglia, Sympathetic; Ganglionectomy; Intraocular Pressure; Male; Norepinephrine; Ocular Hypotension; Ophthalmic Solutions; Phenylephrine; Pupil; Quinazolines; Rabbits; Receptors, Adrenergic, alpha | 1993 |
Vascular responsiveness of rabbit common carotid, renal and femoral arteries to alpha-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carotid Arteries; Dinoprost; Dose-Response Relationship, Drug; Drug Interactions; Female; Femoral Artery; In Vitro Techniques; Male; Phenylephrine; Quinazolines; Rabbits; Renal Artery; Vasoconstriction | 1993 |
Alfuzosin, a selective alpha 1-adrenoceptor antagonist in the lower urinary tract.
Topics: Adenofibroma; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cats; Decerebrate State; Electric Stimulation; Female; Heart; Humans; In Vitro Techniques; Male; Phenylephrine; Prazosin; Prostatic Neoplasms; Quinazolines; Rabbits; Rats; Sympathetic Nervous System; Tumor Cells, Cultured; Urethra; Urinary Tract; Vasoconstriction | 1993 |
Exaggeration of acute liver damage by hepatic sympathetic nerves and circulating catecholamines in perfused liver of rats treated with D-galactosamine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Aspartate Aminotransferases; Calcium; Electric Stimulation; Galactosamine; Isoproterenol; L-Lactate Dehydrogenase; Liver; Male; Norepinephrine; Perfusion; Phenylephrine; Quinazolines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Sympathomimetics | 1996 |
Pharmacological activity of DC-015, a novel potent and selective alpha 1-adrenoceptor antagonist.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Phosphatidylinositols; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Serotonin Antagonists; Vasoconstriction | 1996 |
Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Doxazosin; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Pressure; Prostate; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin | 1996 |
Pharmacological characterization of alpha 1-adrenoceptor subtype mediating regulation of arterial pressure and urethral perfusion pressure in the anaesthetized rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Linear Models; Male; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Urethra | 1996 |
Beta-adrenoceptor stimulation-mediated preconditioning-like cardioprotection in perfused rat hearts.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Creatine Kinase; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Norepinephrine; Phenylephrine; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Timolol; Ventricular Function, Left | 1997 |
Studies of the cellular mechanisms underlying the vasorelaxant effects of rutaecarpine, a bioactive component extracted from an herbal drug.
Topics: Acetylcholine; Alkaloids; Animals; Aorta, Thoracic; Calcimycin; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Estrenes; Gallic Acid; Guanylate Cyclase; Histamine; Indole Alkaloids; Ionophores; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Pertussis Toxin; Phenylephrine; Pyrrolidinones; Quinazolines; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Vasodilator Agents; Virulence Factors, Bordetella | 1997 |
Role of Ca(2+)-independent PKC in alpha 1-adrenoceptor-mediated inotropic responses of neonatal rat hearts.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Calcium; Carbazoles; Diacylglycerol Kinase; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Heart Ventricles; In Vitro Techniques; Indoles; Inositol Phosphates; Isoenzymes; Isoproterenol; Maleimides; Methoxamine; Myocardial Contraction; Myocardium; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Protein Kinase C; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1997 |
Relationship between the effects of alfuzosin on rat urethral and blood pressures and its tissue concentrations.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Male; Phenylephrine; Quinazolines; Rats; Rats, Wistar; Tissue Distribution; Urethra | 1998 |
Functional characterisation of the pharmacological profile of the putative alpha1B-adrenoceptor antagonist, (+)-cyclazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Dose-Response Relationship, Drug; In Vitro Techniques; Isometric Contraction; Male; Mesenteric Arteries; Mice; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Spleen; Vasoconstrictor Agents | 1998 |
Effects of vasodilatory beta-adrenoceptor antagonists on endothelium-derived nitric oxide release in rat kidney.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Benzopyrans; Celiprolol; Desoxycorticosterone; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanolamines; Hypertension; In Vitro Techniques; Kidney; Male; Metergoline; Muscle, Smooth, Vascular; Nebivolol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Pindolol; Piperazines; Piperidines; Platelet Aggregation Inhibitors; Quinazolines; Rats; Rats, Wistar; Renal Circulation; Serotonin Antagonists; Vasoconstriction; Vasodilator Agents | 1999 |
Effects of alpha1-adrenoceptor antagonists on agonist and tilt-induced changes in blood pressure: relationships to uroselectivity.
Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Pressure; Chromones; Consciousness; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Hypotension, Orthostatic; Male; Phenylephrine; Posture; Quinazolines; Rabbits; Rats; Receptors, Adrenergic, alpha-1; Species Specificity; Structure-Activity Relationship; Urethra | 1999 |
Antihypertensive action and blockade of alpha1-adrenoceptors by DL-017, a quinazoline derivative.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kinetics; Laser-Doppler Flowmetry; Male; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Regional Blood Flow; Vasoconstrictor Agents | 2001 |
Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Ileum; In Vitro Techniques; Male; Methoxamine; Mice; Mice, Inbred ICR; Norepinephrine; Pertussis Toxin; Phenylephrine; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin; Virulence Factors, Bordetella; Yohimbine | 2001 |
The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Arteries; Blood Pressure; Cardiovascular System; Female; Gene Targeting; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Piperazines; Quinazolines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Serotonin; Tissue Extracts; Vasoconstriction; Vasoconstrictor Agents; Vasopressins | 2002 |
Signal transduction pathways used by EGF to stimulate protein secretion in rat lacrimal gland.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Eye Proteins; Lacrimal Apparatus; Male; Peroxidase; Phenylephrine; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrphostins | 2003 |
Alpha-adrenergic stimulation of ERK phosphorylation in astrocytes is alpha(2)-specific and may be mediated by transactivation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fibrinolytic Agents; Heparin; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Phenylephrine; Phosphorylation; Quinazolines; Time Factors; Transcriptional Activation; Tyrphostins | 2003 |
Effects of bunazosin hydrochloride on ciliary muscle constriction and matrix metalloproteinase activities.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aqueous Humor; Cattle; Cells, Cultured; Ciliary Body; Drug Combinations; Intraocular Pressure; Isometric Contraction; Latanoprost; Macaca fascicularis; Male; Matrix Metalloproteinases; Muscle Relaxation; Muscle, Smooth; Phenylephrine; Prostaglandins F, Synthetic; Quinazolines; Trabecular Meshwork | 2004 |
Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Androgens; Animals; Autoradiography; Barium Compounds; Chlorides; Clonidine; Cyproterone Acetate; Dioxanes; Gene Expression Regulation; Male; Orchiectomy; Organ Size; Phenylephrine; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; RNA, Messenger; Seminal Vesicles; Testosterone | 2004 |
Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Anthracenes; Aorta, Thoracic; Bacterial Proteins; Benzopyrans; Butadienes; Catheterization; Cell Division; Dipeptides; ErbB Receptors; Flavonoids; Glycine; Hydroxamic Acids; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Organ Culture Techniques; Phenylephrine; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Thrombin; Tyrphostins | 2004 |
Effects of topically instilled bunazosin, an alpha1-adrenoceptor antagonist, on constrictions induced by phenylephrine and ET-1 in rabbit retinal arteries.
Topics: Administration, Topical; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Drug Combinations; Endothelin-1; Ganglionectomy; Injections; Male; Phenylephrine; Quinazolines; Rabbits; Receptors, Endothelin; Retinal Artery; Superior Cervical Ganglion; Vasoconstriction; Vasoconstrictor Agents; Vitreous Body | 2004 |
Vascular responses to alpha1-adrenergic receptors in small rat mesenteric arteries depend on mitochondrial reactive oxygen species.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Dipeptides; Doxycycline; ErbB Receptors; In Vitro Techniques; Matrix Metalloproteinase 7; Mesenteric Arteries; Mitochondria, Muscle; Phenylephrine; Quinazolines; Rats; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Signal Transduction; Tyrphostins; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Effects of different alpha-1 adrenoceptor blockers on proximal urethral function using in vivo isovolumetric pressure changes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cardiovascular System; Male; Phenylephrine; Prazosin; Quinazolines; Rabbits; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Urethra | 2005 |
In vivo study on the effects of alpha1-adrenoceptor antagonists on intraurethral pressure in the prostatic urethra and intraluminal pressure in the vas deferens in male dogs.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Dogs; Dose-Response Relationship, Drug; Ejaculation; Indoles; Male; Naphthalenes; Phenylephrine; Piperazines; Prazosin; Pressure; Prostate; Quinazolines; Sulfonamides; Tamsulosin; Urethra; Vas Deferens | 2008 |
Comparative effect of alfuzosin and tamsulosin on the contractile response of isolated rabbit prostatic and iris dilator smooth muscles: possible model for intraoperative floppy-iris syndrome.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Intraoperative Complications; Iris; Iris Diseases; Male; Muscle, Smooth; Phenylephrine; Prostate; Quinazolines; Rabbits; Sulfonamides; Sympathomimetics; Syndrome; Tamsulosin | 2008 |
Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities.
Topics: Alkaloids; Animals; Antimalarials; Harmaline; Harmine; Peganum; Phenylephrine; Plant Extracts; Plasmodium falciparum; Quinazolines; Rats; Seeds; Vasodilation; Vasodilator Agents | 2008 |
Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways.
Topics: Animals; Arrestins; beta-Arrestin 1; beta-Arrestins; Cell Line; Cell Proliferation; Dipeptides; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Matrix Metalloproteinases; Mutation; Myoblasts, Cardiac; Phenylephrine; Phosphorylation; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Signal Transduction; src-Family Kinases; Transcriptional Activation; Tyrphostins | 2014 |
Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cytochrome b Group; Diabetes Mellitus, Type 2; Diabetic Angiopathies; ErbB Receptors; Mice; Mice, Knockout; NADPH Oxidase 4; NADPH Oxidases; Phenylephrine; Quinazolines; Tyrphostins; Vasoconstriction; Vasodilation | 2015 |
Both α
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Male; Muscle Contraction; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Thymine; Yohimbine | 2021 |