quinazolines has been researched along with oridonin in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikejima, T; Kang, N; Onodera, S; Qiu, F; Tashiro, S; Zhang, JH | 1 |
| Fan, SM; Ikejima, T; Onodera, S; Tashiro, S; Ye, YC; Yu, Y | 1 |
| Cai, F; Cao, W; Duan, C; Fan, C; He, Z; Huang, Q; Liu, Y; Wang, J; Wang, X; Xiao, X; Zhang, L | 1 |
3 other study(ies) available for quinazolines and oridonin
| Article | Year |
|---|---|
Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Carcinoma, Squamous Cell; Cell Line, Tumor; Diterpenes, Kaurane; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Fas-Associated Death Domain Protein; Humans; Laryngeal Neoplasms; Membrane Potential, Mitochondrial; Oxidative Stress; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Reactive Oxygen Species; Signal Transduction; Sirtuin 1; Tyrphostins | 2010 |
The tyrphostin AG1478 augments oridonin-induced A431 cell apoptosis by blockage of JNK MAPK and enhancement of oxidative stress.
Topics: Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Tyrphostins | 2012 |
Oridonin inhibits gefitinib-resistant lung cancer cells by suppressing EGFR/ERK/MMP-12 and CIP2A/Akt signaling pathways.
Topics: A549 Cells; Animals; Autoantigens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 12; Membrane Proteins; Mice; Phosphorylation; Quinazolines; Xenograft Model Antitumor Assays | 2016 |