Compounds > quinazolines
Page last updated: 2024-08-21

quinazolines and nutlin-3a

quinazolines has been researched along with nutlin-3a in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, HS; Lee, SY; Shin, SJ1
Dewhirst, MW; Geradts, J; Henao, R; Kim, J; Kim, WJ; Kornbluth, S; Kurokawa, M; Liu, L; Lucas, JE; Matsuura, K; Ran, X; Ribar, TJ; Spector, NL; Wang, S; Xia, W1
Fu, Y; He, Q; Lin, G; Lou, J; Ma, J; Wu, Y; Yang, B; Zheng, L; Zhu, H1
Abujamra, AL; Alemar, B; Ashton-Prolla, P; de Farias, CB; Giacomazzi, J; Hainaut, P; Hautefeuille, A; Izetti, P; Lenz, G; Osvaldt, AB; Roesler, R; Schwartsmann, G1

Other Studies

4 other study(ies) available for quinazolines and nutlin-3a

ArticleYear
ERK1/2 activation mediated by the nutlin‑3‑induced mitochondrial translocation of p53.
    International journal of oncology, 2013, Volume: 42, Issue:3

    Topics: Antioxidants; Apoptosis; Benzothiazoles; Butadienes; Cell Line, Tumor; Cyclic N-Oxides; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Osteosarcoma; Phosphorylation; Piperazines; Protein Transport; Quinazolines; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Toluene; Tumor Suppressor Protein p53; Tyrphostins

2013
A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.
    Science signaling, 2013, May-07, Volume: 6, Issue:274

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Imidazoles; Immunoblotting; Lapatinib; Mice; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Nuclear Proteins; Phosphoprotein Phosphatases; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-mdm2; Quinazolines; Receptor, ErbB-2; RNA Interference; Signal Transduction; Substrate Specificity; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays

2013
Nutlin-3 inhibits epithelial-mesenchymal transition by interfering with canonical transforming growth factor-β1-Smad-Snail/Slug axis.
    Cancer letters, 2014, Jan-01, Volume: 342, Issue:1

    Topics: Antigens, CD; Antineoplastic Agents; Cadherins; Cell Line, Tumor; Cell Movement; Drug Evaluation, Preclinical; Drug Synergism; Epithelial-Mesenchymal Transition; ErbB Receptors; Gefitinib; Gene Expression; Humans; Imidazoles; Lapatinib; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Quinazolines; RNA, Messenger; Signal Transduction; Smad Proteins; Snail Family Transcription Factors; Transcription Factors; Transforming Growth Factor beta1; Up-Regulation

2014
PRIMA-1, a mutant p53 reactivator, induces apoptosis and enhances chemotherapeutic cytotoxicity in pancreatic cancer cell lines.
    Investigational new drugs, 2014, Volume: 32, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Aza Compounds; Boronic Acids; Bortezomib; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Line, Tumor; Cell Survival; Deoxycytidine; Erlotinib Hydrochloride; Gemcitabine; Humans; Imidazoles; Mutation; Pancreatic Neoplasms; Piperazines; Pyrazines; Quinazolines; RNA, Small Interfering; Tumor Suppressor Protein p53

2014