Page last updated: 2024-08-21

quinazolines and nad

quinazolines has been researched along with nad in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's1 (8.33)18.2507
2000's3 (25.00)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Banasik, M; Komura, H; Shimoyama, M; Ueda, K1
Arora, RC; Kishor, K; Parmar, SS; Seth, PK1
Nagar, S; Parmar, SS1
Arora, RC; Gupta, TK; Parmar, SS; Rastogi, VK1
Brumleve, SJ; Chaturvedi, AK; Chaudhary, A; Parmar, SS1
Berente, Z; Halmosi, R; Literati-Nagy, P; Osz, E; Sumegi, B; Toth, K1
García-Martín, E; Gutiérrez-Merino, C; Martín-Romero, FJ1
Kaundal, RK; Shah, KK; Sharma, SS1
Abagyan, R; Behera, R; Katiyar, S; Kufareva, I; Mensa-Wilmot, K; Ogata, Y; Pollastri, M; Thomas, SM1
Alefishat, E; Alexander, SP; Ralevic, V1
Alsaid, MS; Arafa, RK; Dinkova-Kostova, AT; Elghazawy, NH; Ghorab, MM; Higgins, M; Shahat, AA1
Deaton, DN; Haffner, CD; Henke, BR; Jeune, MR; Shearer, BG; Stewart, EL; Stuart, JD; Ulrich, JC1

Other Studies

12 other study(ies) available for quinazolines and nad

ArticleYear
Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase.
    The Journal of biological chemistry, 1992, Jan-25, Volume: 267, Issue:3

    Topics: Acetophenones; ADP Ribose Transferases; Animals; Benzamides; Cattle; Enzyme Inhibitors; Fatty Acids, Nonesterified; Isoquinolines; Kinetics; NAD; Naphthalenes; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Pyrimidines; Quinazolines; Quinolines; Structure-Activity Relationship; Thymus Gland

1992
Role of alkyl substitution in 2,3-disubstituted and 3-substituted 4-quinazolones on the inhibition of pyruvic acid oxidation.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:1

    Topics: Animals; Brain; Depression, Chemical; Ketones; Male; Manometry; NAD; Oxygen Consumption; Pyruvates; Quinazolines; Rats

1969
Role of ring substitution on the inhibition of nicotinamide adenine dinucleotide dependent oxidations by 2-methyl-3-ortho-tolyl-6-hydroxy-4-quinazolone.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:3

    Topics: Animals; Brain; Chemical Phenomena; Chemistry; Citrates; Citric Acid Cycle; Fumarates; Glutamates; In Vitro Techniques; Ketoglutaric Acids; Malates; Male; NAD; Oxidation-Reduction; Oxygen; Pyruvates; Quinazolines; Rats; Sodium; Succinates

1969
Correlation between selective inhibition of NAD-dependent oxidations and anticonvulsant property of quinazolone allylethers and quinazolone allyphenols.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Citrates; Ethers; Female; Fumarates; Glutamates; Glutarates; Hydroxybutyrates; Male; NAD; Oxidation-Reduction; Phenols; Quinazolines; Rats; Succinates

1970
Substituted piperazinoquinazolones: relationship between selective inhibition of nicotinamide adenine dinucleotide-dependent oxidations and anticonvulsant activity.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3

    Topics: Animals; Anticonvulsants; Brain; Citrates; Hydroxybutyrates; In Vitro Techniques; Isocitrates; Ketoglutaric Acids; Male; NAD; ortho-Aminobenzoates; Oxidation-Reduction; Pentylenetetrazole; Piperazines; Pyruvates; Quinazolines; Rats; Seizures; Structure-Activity Relationship

1974
Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system.
    Molecular pharmacology, 2001, Volume: 59, Issue:6

    Topics: Aminobenzoates; Animals; DNA; DNA Damage; Electron Transport Complex IV; Energy Metabolism; Enzyme Inhibitors; Heart; In Vitro Techniques; Lipid Peroxidation; Male; Mitochondria; Myocardium; NAD; Oxidation-Reduction; Oximes; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury

2001
Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells.
    Journal of neurochemistry, 2002, Volume: 82, Issue:3

    Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Membrane; Cell Survival; Cell-Free System; Cells, Cultured; Cerebellum; Cytoprotection; DNA Fragmentation; Enzyme Inhibitors; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; NADP; Neurons; Oxidative Stress; Potassium; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Superoxide Dismutase

2002
Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation.
    Life sciences, 2006, Nov-10, Volume: 79, Issue:24

    Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cell Survival; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Hydrogen Peroxide; Male; Middle Cerebral Artery; Molsidomine; NAD; Neuroprotective Agents; PC12 Cells; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2006
Lapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffolds.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Chromatography, Affinity; ErbB Receptors; HeLa Cells; Humans; Lapatinib; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Targeted Therapy; Morpholines; NAD; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Purines; Quinazolines; Structural Homology, Protein; Trypanosoma brucei brucei

2013
Effects of NAD at purine receptors in isolated blood vessels.
    Purinergic signalling, 2015, Volume: 11, Issue:1

    Topics: Acetamides; Animals; Aorta, Thoracic; Coronary Vessels; Male; Mesenteric Arteries; NAD; Palmitoyl Coenzyme A; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic; Swine; Triazoles; Vasodilation

2015
NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Kelch-Like ECH-Associated Protein 1; Mice; Models, Molecular; Molecular Structure; NAD; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Protein Binding; Quinazolines; Structure-Activity Relationship

2016
2,4-Diamino-8-quinazoline carboxamides as novel, potent inhibitors of the NAD hydrolyzing enzyme CD38: Exploration of the 2-position structure-activity relationships.
    Bioorganic & medicinal chemistry, 2018, 05-01, Volume: 26, Issue:8

    Topics: ADP-ribosyl Cyclase 1; Amides; Animals; Binding Sites; Enzyme Inhibitors; Half-Life; Humans; Mice; Molecular Docking Simulation; NAD; Protein Structure, Tertiary; Quinazolines; Structure-Activity Relationship

2018