Page last updated: 2024-08-21

quinazolines and mrs 1220

quinazolines has been researched along with mrs 1220 in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	27 (87.10)	29.6817
2010's	2 (6.45)	24.3611
2020's	2 (6.45)	2.80

Authors

Authors	Studies
Jacobson, KA; Ji, XD; Lvovskiy, D; Melman, N; Webb, TR	1
Abbracchio, MP; Barbieri, D; Brambilla, R; Cattabeni, F; Ceruti, S; Franceschi, C; Jacobson, KA; Kim, YC; Klotz, KN; Lohse, MJ	1
Bar-Yehuda, S; Barer, F; Farbstein, T; Fishman, P; Ohana, G	1
Abebe, W; Mozaffari, MS; Warren, BK	1
Clark, KL; Guyton, RA; Nakamura, M; Velez, DV; Vinten-Johansen, J; Zhao, ZQ	1
Brand, A; Eschke, D; Nieber, K; Vissiennon, Z	1
Khoo, HE; Mittal, RA; Tan, CH	1
Broadley, KJ; Spruntulis, LM	1
Ashton, K; Berr, SS; Cerniway, RJ; Harrison, GJ; Headrick, JP; Paul Matherne, G; Peart, J; Regan, S	1
Jacobson, KA; Jacobson, MA; Ledent, C; Morrison, RR; Mustafa, SJ; Talukder, MA	1
Ezeamuzie, CI; Philips, E	1
Saccone, GT; Toouli, J; Woods, CM	1
Bremer, HC; Elsner, P; Girolomoni, G; Herouy, Y; Idzko, M; Mockenhaupt, M; Norgauer, J; Panther, E; Sorichter, S; Windisch, W	1
Baharav, E; Bar-Yehuda, S; Fishman, P; Halpren, M; Madi, L; Ochaion, A; Rath-Wolfson, L; Silberman, D; Weinberger, A	1
Cavalheiro, EA; da Silva Fernandes, MJ; Doná, F; Ferreira, AT; Vianna, EP	1
Cortés, D; Díaz-Cruz, A; Guinzberg, R; Piña, E; Riveros-Rosas, H; Villalobos-Molina, R	1
Coppi, E; Corradetti, R; Pedata, F; Pugliese, AM; Spalluto, G	1
Broadley, KJ; Clark, JH; James, S; Kidd, EJ; Martin, TJ; Yates, L	1
Mulè, F; Serio, R; Zizzo, MG	1
Gao, C; Gao, N; Hu, HZ; Liu, S; Wood, JD; Xia, Y	1
Battastini, AM; Bavaresco, L; Bernardi, A; Delgado-Cañedo, A; Jacques-Silva, MC; Lenz, G; Wink, MR	1
Chen, Z; Christofi, FL; Cooke, HJ; Grants, I; Melvin, WS; Mikami, DJ; Needleman, BJ; Wang, Y; Wunderlich, JE; Yu, JG	1
Coe, IR; Naydenova, Z; Rose, JB	1
Broadley, KJ; Smith, N	1
Ahlawat, R; Chavez-Valdez, R; Cristofalo, EA; Gauda, EB; Nathan, A; Wills-Karp, M	1
Miriel, VA; Rivers, RJ; Thengchaisri, N	1
Aung, HH; Barnholt, KE; Kota, RS; Rutledge, JC	1
Arnould, I; Bellamy, JF; Besnard, F; Blouquit-Laye, S; Buenestado, A; Chapelier, A; Devillier, P; Grassin Delyle, S; Naline, E	1
Burton, VJ; Butler, M; Parkinson, SJ; Pearson, R; Sanmugalingam, D; Smith, P; Watson, RP; Wilson, T	1
Jang, HS; Kerkvliet, NI; Kolluri, SK; Liefwalker, DF; O'Donnell, EF	1
Beesley, J; Gause, WC; Haskó, G; Lovászi, M; Németh, ZH; Pacher, P	1

Trials

1 trial(s) available for quinazolines and mrs 1220

Article	Year
Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo. European journal of immunology, 2012, Volume: 42, Issue:12 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Chemotaxis; Colitis; Dextran Sulfate; Disease Models, Animal; Humans; Immunity, Innate; Inflammation; Mice; Mice, Knockout; Neutrophils; Quinazolines; Receptor, Adenosine A3; Triazoles; Up-Regulation	2012

Article

Year

Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo.

European journal of immunology, 2012, Volume: 42, Issue:12

Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Chemotaxis; Colitis; Dextran Sulfate; Disease Models, Animal; Humans; Immunity, Innate; Inflammation; Mice; Mice, Knockout; Neutrophils; Quinazolines; Receptor, Adenosine A3; Triazoles; Up-Regulation

2012

Other Studies

30 other study(ies) available for quinazolines and mrs 1220

Article	Year
The utilization of a unified pharmacophore query in the discovery of new antagonists of the adenosine receptor family. Bioorganic & medicinal chemistry letters, 2000, Jan-03, Volume: 10, Issue:1 Topics: Adenosine-5'-(N-ethylcarboxamide); Databases, Factual; Flavonoids; Guanosine 5'-O-(3-Thiotriphosphate); Information Storage and Retrieval; Kinetics; Ligands; Molecular Conformation; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Structure-Activity Relationship; Triazoles	2000
Activation of the A3 adenosine receptor affects cell cycle progression and cell growth. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Analysis of Variance; Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Membrane; Cell Survival; CHO Cells; Cricetinae; Dihydropyridines; Flow Cytometry; Humans; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Triazoles	2000
Adenosine acts as a chemoprotective agent by stimulating G-CSF production: a role for A1 and A3 adenosine receptors. Journal of cellular physiology, 2000, Volume: 183, Issue:3 Topics: Adenosine; Animals; Bone Marrow Cells; Cell Cycle; Cell Division; Cells, Cultured; Cyclophosphamide; Granulocyte Colony-Stimulating Factor; Humans; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines	2000
Renal adenosine A3 receptors in the rat: assessment of functional role. Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:5 Topics: Animals; Dihydropyridines; Diuresis; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Potassium; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Inbred WKY; Receptor, Adenosine A3; Receptors, Purinergic P1; Sodium; Triazoles; Urodynamics; Xanthines	2000
A novel adenosine analog, AMP579, inhibits neutrophil activation, adherence and neutrophil-mediated injury to coronary vascular endothelium. European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1 Topics: Animals; Cell Adhesion; Cell Degranulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Male; Neutrophil Activation; Neutrophils; Pyridines; Quinazolines; Superoxides; Triazines; Triazoles; Vasodilation; Xanthines	2000
Adenosine A(1) and A(3) receptors mediate inhibition of synaptic transmission in rat cortical neurons. Neuropharmacology, 2001, Volume: 40, Issue:1 Topics: Adenosine; Animals; Cerebral Cortex; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Male; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, Purinergic P1; Synaptic Transmission; Triazoles; Xanthines	2001
Adenosine modulates cell growth in baby hamster kidney (BHK) cells. BioFactors (Oxford, England), 2000, Volume: 11, Issue:4 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Kinase; Animals; Cell Division; Cell Line; Cricetinae; Enzyme Inhibitors; Kidney; Mutation; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles	2000
A3 receptors mediate rapid inflammatory cell influx into the lungs of sensitized guinea-pigs. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2001, Volume: 31, Issue:6 Topics: Adenosine Monophosphate; Animals; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Leukocyte Count; Leukocytes; Lung; Male; Ovalbumin; Pneumonia; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles	2001
Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart. Cardiovascular research, 2002, Volume: 53, Issue:1 Topics: Adenosine; Amino Acids; Animals; Creatine; Heart Rate; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Phenethylamines; Pipecolic Acids; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Xanthines	2002
Targeted deletion of adenosine A(3) receptors augments adenosine-induced coronary flow in isolated mouse heart. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6 Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Gene Deletion; Heart Rate; Mice; Mice, Knockout; Phenethylamines; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Vasodilation; Ventricular Pressure	2002
Positive coupling of atypical adenosine A3 receptors on human eosinophils to adenylyl cyclase. Biochemical and biophysical research communications, 2003, Jan-17, Volume: 300, Issue:3 Topics: Adenosine; Adenylyl Cyclases; Adult; Cell Degranulation; Cyclic AMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eosinophils; Histamine; Humans; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles	2003
A2A and A3 receptors mediate the adenosine-induced relaxation in spontaneously active possum duodenum in vitro. British journal of pharmacology, 2003, Volume: 138, Issue:7 Topics: Adenosine; Animals; Duodenum; Female; In Vitro Techniques; Male; Opossums; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Quinazolines; Receptors, Purinergic P1; Tetrodotoxin; Time Factors; Triazoles; Xanthines	2003
Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors. Journal of cellular physiology, 2004, Volume: 199, Issue:1 Topics: Actins; Antigens, CD; Caffeine; Calcium; Cell Differentiation; Chemotaxis; Cytokines; Dendritic Cells; Dose-Response Relationship, Drug; Flow Cytometry; Histocompatibility Antigens Class I; Humans; Inosine; Pertussis Toxin; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Triazoles; Xanthines	2004
Antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models. The Journal of rheumatology, 2005, Volume: 32, Issue:3 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Collagen; Dose-Response Relationship, Drug; Female; Joints; Lymph Nodes; Male; Mice; Mice, Inbred DBA; Quinazolines; Rats; Receptor, Adenosine A3; Spleen; Triazoles; Tumor Necrosis Factor-alpha	2005
Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats. Epilepsia, 2005, Volume: 46 Suppl 5 Topics: 5'-Nucleotidase; Adenosine; Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; In Situ Nick-End Labeling; Male; Neuronal Plasticity; Neuroprotective Agents; Pilocarpine; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic P1; Status Epilepticus; Synapses; Triazoles; Xanthines	2005
Inosine released after hypoxia activates hepatic glucose liberation through A3 adenosine receptors. American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:5 Topics: Adenosine; Adenosine A3 Receptor Antagonists; Animals; Calcium; Cell Hypoxia; Cyclic AMP; Gluconeogenesis; Glucose; Glycogen Phosphorylase; Glycogenolysis; Hepatocytes; Inosine; Liver; Male; Phylogeny; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, G-Protein-Coupled; Receptors, Purinergic; Receptors, Purinergic P1; Triazoles; Urea	2006
A3 adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro. British journal of pharmacology, 2006, Volume: 147, Issue:5 Topics: Action Potentials; Adenosine A3 Receptor Antagonists; Animals; Brain Ischemia; Hippocampus; Hypoglycemia; Hypoxia; Male; Pyridines; Quinazolines; Rats; Rats, Wistar; Receptor, Adenosine A3; Synaptic Transmission; Time Factors; Triazoles	2006
Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors. Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:2 Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Iodine Radioisotopes; Ligands; Magnesium Chloride; Quinazolines; Radioligand Assay; Receptor, Adenosine A3; Recombinant Proteins; Transfection; Triazoles	2006
Inhibitory responses to exogenous adenosine in murine proximal and distal colon. British journal of pharmacology, 2006, Volume: 148, Issue:7 Topics: Adenosine; Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Signal Transduction; Theobromine; Triazoles; Xanthines	2006
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine. American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles	2007
Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines. European journal of pharmacology, 2007, Aug-13, Volume: 569, Issue:1-2 Topics: 5'-Nucleotidase; Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glioma; Humans; Indomethacin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Time Factors; Triazoles; Xanthines	2007
Dual purinergic synaptic transmission in the human enteric nervous system. American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:2 Topics: Aniline Compounds; Calcium; Chloride Channels; Electric Stimulation; Enteric Nervous System; Fluorescent Dyes; Humans; Microscopy, Confocal; Nerve Fibers; Neurons; Obesity; Quinazolines; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Submucous Plexus; Synaptic Transmission; Triazoles; Type C Phospholipases; Vasoactive Intestinal Peptide; Xanthenes	2008
Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Cell Hypoxia; Cell Line; Cell Survival; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Inosine; Mice; Myocytes, Cardiac; Nucleoside Transport Proteins; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A3; Thioinosine; Triazoles; Up-Regulation; Xanthines	2008
Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, Volume: 38, Issue:9 Topics: Adenosine Monophosphate; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dexamethasone; Dose-Response Relationship, Drug; Guinea Pigs; Immunization; Purinergic P1 Receptor Antagonists; Purines; Quinazolines; Receptors, Purinergic P1; Triazines; Triazoles; Xanthines	2008
Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors. Pediatric research, 2009, Volume: 65, Issue:2 Topics: Acetamides; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adult; Blotting, Western; Caffeine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fetal Blood; Humans; Infant, Newborn; Interleukins; Lipopolysaccharides; Middle Aged; Monocytes; Purines; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Triazines; Triazoles; Tumor Necrosis Factor-alpha; Xanthines	2009
Multiple receptor subtypes and multiple mechanisms of dilation are involved in vascular network dilation caused by adenosine. Microvascular research, 2009, Volume: 77, Issue:3 Topics: Adenosine; Animals; Arterioles; Cricetinae; Drug Antagonism; Endothelium, Vascular; Flavins; Mesocricetus; Methacholine Chloride; Nitroprusside; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Triazines; Triazoles; Vasodilation; Vasodilator Agents	2009
Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation. Journal of immunology (Baltimore, Md. : 1950), 2009, Nov-15, Volume: 183, Issue:10 Topics: Adenosine; Adenosine A3 Receptor Antagonists; Analgesics; Animals; Cell Line; Dihydropyridines; Gene Expression; Humans; Interferon-gamma; Janus Kinases; Macrophage Activation; Macrophages; Mice; Microarray Analysis; Phosphorylation; Quinazolines; Receptor, Adenosine A3; Serine; Signal Transduction; STAT1 Transcription Factor; Transcriptional Activation; Triazoles; Tyrosine	2009
The role of adenosine receptors in regulating production of tumour necrosis factor-alpha and chemokines by human lung macrophages. British journal of pharmacology, 2010, Volume: 159, Issue:6 Topics: Acetamides; Cells, Cultured; Chemokines; Female; Humans; Lipopolysaccharides; Lung; Macrophages, Alveolar; Male; Middle Aged; Protein Subunits; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Triazines; Triazoles; Tumor Necrosis Factor-alpha	2010
Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects. Apoptosis : an international journal on programmed cell death, 2021, Volume: 26, Issue:5-6 Topics: Animals; Antineoplastic Agents; Apoptosis; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Line, Tumor; Fas Ligand Protein; Humans; Ligands; Mice; Quinazolines; Receptors, Aryl Hydrocarbon; Signal Transduction; Small Molecule Libraries; Transcriptional Activation; Triazoles	2021
Inosine monophosphate and inosine differentially regulate endotoxemia and bacterial sepsis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:11 Topics: Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Animals; Disease Models, Animal; Endotoxemia; Inosine; Inosine Monophosphate; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Pneumonia, Pneumococcal; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Signal Transduction; Streptococcus pneumoniae; Triazoles; Tumor Necrosis Factor-alpha	2021