quinazolines has been researched along with morphine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (28.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 9 (36.00) | 24.3611 |
| 2020's | 7 (28.00) | 2.80 |
| Authors | Studies |
|---|---|
| Awata, H; Inukai, T; Koga, Y; Kurokawa, H; Yanagi, Y | 1 |
| Gulati, OD; Gupta, AK; Makol, R; Raghunath, PR; Shah, DS | 1 |
| Saito, C; Sakai, S; Takagi, H; Yamamoto, H; Yukawa, Y | 1 |
| Kawakami, M; Negoro, H; Takahashi, T | 1 |
| DeStevens, G | 1 |
| Weis, J | 1 |
| Holtzman, SG | 1 |
| Doods, H; Jhamandas, K; Ma, W; Powell, KJ; Quirion, R; Sutak, M | 1 |
| Bernard, PS; Blatter, HM; Chernov, HI; Plummer, AJ; Wilson, DE | 1 |
| Chabot, JG; Ma, W; Quirion, R; Wang, Z | 2 |
| Chen, C; Fujioka, N; Gupta, K; Gupta, V; Johnson, KN; Kratzke, RA; Li, Y; Nguyen, J; Niehans, G; Pasrija, T | 1 |
| Arndt, K; Corradini, L; Doods, H; Hirsch, S; Just, S | 1 |
| Bastian, G; Bourgoin, S; Hamon, M; Kayser, V; Michot, B | 1 |
| Caselli, G; Ferrari, F; Lanza, M; Menghetti, I; Tremolada, D | 1 |
| He, XH; Li, JX; Qiu, Y; Zhang, Y | 1 |
| Gu, JK; Hao, M; Jiang, HD; Jim Wang, ZJ; Ju, HX; Li, L; Xu, MC; Yang, ZZ; Yu, LS; Zeng, S | 1 |
| Kibaly, C; Law, PY; Liu, JG; Loh, HH; McGarrah, PW; Song, KY; Wang, YJ; Xu, C; Zhang, L | 1 |
| Han, C; He, L; Lei, D; Li, S; Liu, L; Ma, T; Wen, S; Xie, S; Zhou, H | 1 |
| Bonazzi, A; Borsi Franchini, M; Caselli, G; Comi, E; Ferrari, F; Lanza, M; Milia, C; Rovati, LC; Sabatini, C; Sala, E | 1 |
| Bogacka, J; Ciechanowska, A; Dobrogowski, J; Makuch, W; Mika, J; Pawlik, K; Popiolek-Barczyk, K; Przeklasa-Muszynska, A; Rojewska, E | 1 |
| Bogacka, J; Ciapała, K; Dobrogowski, J; Kwiatkowski, K; Mika, J; Pawlik, K; Przeklasa-Muszynska, A | 1 |
| Chen, Z; Hu, R; Jiang, H; Sun, Y; Yan, J; Yang, Y | 1 |
| Bian, X; Li, X; Sun, Y; Tian, W; Tian, Y; Xu, J; Zhao, H | 1 |
| Hu, R; Jiang, H; Li, W; Sun, Y; Wang, Z; Yan, J; Yang, Y | 1 |
25 other study(ies) available for quinazolines and morphine
| Article | Year |
|---|---|
[Analgetic and antipyretic activity of SL-573 (author's transl)].
Topics: Afferent Pathways; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Body Temperature; Dose-Response Relationship, Drug; Drug Tolerance; Evoked Potentials; Fever; Male; Mice; Morphine; Naloxone; Physical Stimulation; Quinazolines; Quinazolinones; Rabbits; Rats; Stimulation, Chemical; Typhoid-Paratyphoid Vaccines; Yeast, Dried | 1978 |
Neuromuscular blocking action of 2-(2-(3-pyridyl) vinyl)-3-0-tolyl-3, 4-dihydroquinazoline-4-one (SRC 909).
Topics: Abdominal Muscles; Acetylcholine; Animals; Anura; Atropine; Calcium; Carbachol; Cats; Choline; Cold Temperature; Dose-Response Relationship, Drug; Female; Gallamine Triethiodide; Glycols; In Vitro Techniques; Leg; Male; Methysergide; Morphine; Muscle Contraction; Muscles; Neuromuscular Blocking Agents; Pentolinium Tartrate; Phrenic Nerve; Physostigmine; Potassium Chloride; Pyridines; Quinazolines; Quinazolinones; Rats; Sciatic Nerve; Tubocurarine; Vinyl Compounds | 1974 |
Pharmacological studies on 2-methyl-3(2'-methyl-4'-chlorophenyl)-5-chloro-4[H)-quinazolinone (SL-164).
Topics: Aggression; Analgesics; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Blood Pressure; Cats; Chlordiazepoxide; Chlorpromazine; Drug Synergism; Electroencephalography; Haplorhini; Heart; Hexobarbital; Humans; Hypnotics and Sedatives; In Vitro Techniques; Male; Meprobamate; Methaqualone; Mice; Morphine; Muscle Relaxants, Central; Muscle, Smooth; Pentylenetetrazole; Quinazolines; Rabbits; Rats; Respiration; Strychnine; Tranquilizing Agents | 1969 |
Neuropharmacological studies on the mechanisms of paradoxical sleep in the rabbit.
Topics: Animals; Arousal; Cerebral Ventricles; Chlordiazepoxide; Chlorpromazine; Diazepam; Electric Stimulation; Electroencephalography; Hypnotics and Sedatives; Meprobamate; Morphine; Pentobarbital; Quinazolines; Rabbits; Sleep; Tranquilizing Agents | 1966 |
The chemistry of some new analgetics.
Topics: Analgesics; Chemistry, Pharmaceutical; Isoquinolines; Morphinans; Morphine; Piperidines; Quinazolines | 1969 |
Pharmacological investigation of 3-(beta-dimethylaminoethyl)-2-thio-2,4-[1H, 3H]-quinazoline-dione, hydrochloride (QB 15B).
Topics: Animals; Atropine; Guinea Pigs; Mice; Morphine; Quinazolines; Rats | 1967 |
Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, have a dopamine component in monkeys.
Topics: Animals; Cocaine; Dextroamphetamine; Discrimination Learning; Dopamine; Dopamine Agonists; Dopamine Antagonists; Generalization, Stimulus; Male; Morphine; Neurons; Norepinephrine; Phencyclidine; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Biogenic Amine; Saimiri; Selective Serotonin Reuptake Inhibitors; Triazoles | 1999 |
Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Drug Tolerance; Male; Morphine; Peptide Fragments; Piperazines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin Gene-Related Peptide; Receptors, N-Methyl-D-Aspartate; Substance P | 2000 |
Analgetic activity of a quinazoline.
Topics: Aminopyrine; Analgesics; Animals; Dental Pulp; Hot Temperature; Male; Mice; Morphine; Pain; Quinazolines; Rats | 1967 |
Calcitonin gene-related peptide as a regulator of neuronal CaMKII-CREB, microglial p38-NFκB and astroglial ERK-Stat1/3 cascades mediating the development of tolerance to morphine-induced analgesia.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Calcitonin Receptor-Like Protein; CREB-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Male; Morphine; Nerve Tissue Proteins; NF-kappaB-Inducing Kinase; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Physical Stimulation; Piperazines; Protein Serine-Threonine Kinases; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Protein 1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; STAT3 Transcription Factor | 2010 |
Morphological evidence for the involvement of microglial p38 activation in CGRP-associated development of morphine antinociceptive tolerance.
Topics: Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Drug Tolerance; Male; Microglia; Morphine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Piperazines; Quinazolines; Rats; Rats, Sprague-Dawley | 2010 |
Morphine-induced epidermal growth factor pathway activation in non-small cell lung cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Transformed; Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Humans; Lung Neoplasms; MAP Kinase Signaling System; Morphine; Quinazolines; Receptors, Opioid, mu | 2011 |
The CGRP receptor antagonist BIBN4096BS peripherally alleviates inflammatory pain in rats.
Topics: Administration, Topical; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Freund's Adjuvant; Inflammation; Ketorolac; Male; Morphine; Neurons; Osteoarthritis; Pain; Pain Measurement; Piperazines; Quinazolines; Rats; Rats, Wistar; Spinal Cord | 2013 |
Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Dipeptides; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Organoplatinum Compounds; Oxaliplatin; Piperazines; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Spinal Cord; Touch; TRPA1 Cation Channel; TRPC Cation Channels; Tryptamines | 2014 |
Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Binding Sites; Drug Synergism; Female; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Quinazolines; Rats, Sprague-Dawley; Yohimbine | 2014 |
Discriminative stimulus effects of the novel imidazoline I₂ receptor ligand CR4056 in rats.
Topics: Animals; Benzofurans; Imidazoles; Imidazoline Receptors; Imidazolines; Male; Methadone; Morphine; Quinazolines; Rats | 2014 |
Brain-derived neurotrophic factor involved epigenetic repression of UGT2B7 in colorectal carcinoma: A mechanism to alter morphine glucuronidation in tumor.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Azepines; Brain-Derived Neurotrophic Factor; Cancer Pain; Cell Line, Tumor; Colorectal Neoplasms; Drug Tolerance; Epigenetic Repression; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucuronosyltransferase; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Male; Middle Aged; Morphine; Morphine Derivatives; Neoplasm Proteins; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Quinazolines; RNA Interference; RNA, Small Interfering; Transcription Factors; Up-Regulation | 2017 |
Src-dependent phosphorylation of μ-opioid receptor at Tyr
Topics: Animals; Behavior, Animal; Benzodioxoles; Body Weight; HEK293 Cells; Humans; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Naloxone; Narcotic Antagonists; Phosphorylation; Proto-Oncogene Proteins c-fyn; Quinazolines; Receptors, Opioid, mu; RNA Interference; RNA, Small Interfering; src-Family Kinases; Tyrosine | 2017 |
Morphine induces the differentiation of T helper cells to Th2 effector cells via the PKC-θ-GATA3 pathway.
Topics: Analgesics, Opioid; Animals; Cell Differentiation; GATA3 Transcription Factor; Interferon-gamma; Interleukin-4; Male; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotic Antagonists; Protein Kinase C-theta; Pyrroles; Quinazolines; T-Lymphocytes, Helper-Inducer | 2020 |
Improved efficacy, tolerance, safety, and abuse liability profile of the combination of CR4056 and morphine over morphine alone in rodent models.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Imidazoles; Morphine; Quinazolines; Rats; Rodentia | 2020 |
CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
Topics: Analgesics, Opioid; Animals; Cold Temperature; Cytokines; Disease Models, Animal; Drug Synergism; Ganglia, Spinal; Hyperalgesia; Male; Mice; Morphine; Neuralgia; Peripheral Nerve Injuries; Quinazolines; Rats, Wistar; Receptors, CCR4; Sciatic Nerve; Spinal Cord; Touch | 2020 |
CCR4 Antagonist (C021) Administration Diminishes Hypersensitivity and Enhances the Analgesic Potency of Morphine and Buprenorphine in a Mouse Model of Neuropathic Pain.
Topics: Animals; Behavior, Animal; Biomarkers; Buprenorphine; Disease Models, Animal; Drug Synergism; Injections, Spinal; Male; Mice; Models, Animal; Morphine; Neuralgia; Pain Management; Quinazolines; Receptors, CCR4; Time Factors; Treatment Outcome | 2020 |
Activation of the spinal EGFR signaling pathway in a rat model of cancer-induced bone pain with morphine tolerance.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cancer Pain; Carcinoma 256, Walker; Drug Tolerance; Enzyme Inhibitors; ErbB Receptors; MAP Kinase Signaling System; Microglia; Morphine; Phosphorylation; Quinazolines; Rats; Spinal Cord; Tibia; Tyrphostins | 2021 |
Morphine Prevents Ischemia/Reperfusion-Induced Myocardial Mitochondrial Damage by Activating δ-opioid Receptor/EGFR/ROS Pathway.
Topics: Animals; Epidermal Growth Factor; ErbB Receptors; Mitochondria, Heart; Morphine; Myocytes, Cardiac; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Reactive Oxygen Species; Receptors, Opioid; Reperfusion; Reperfusion Injury; RNA, Small Interfering; Superoxides; Tyrphostins | 2022 |
Morphine promotes microglial activation by upregulating the EGFR/ERK signaling pathway.
Topics: Animals; CD11b Antigen; Cell Line; Cell Movement; Drug Tolerance; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation; Interleukin-1beta; Mice; Microglia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morphine; Phosphorylation; Quinazolines; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrphostins | 2021 |