Page last updated: 2024-08-21

quinazolines and methionine

quinazolines has been researched along with methionine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bagshawe, KD; Bradshaw, T; Mellor, B; Melton, RG; Pedley, RB; Searle, F; Sherwood, RF1
Gröger, D; Johne, S; Waiblinger, K1
Reddy, GK1
Aoe, K; Aoe, M; Asano, H; Date, H; Ichihara, S; Inukai, M; Ito, S; Kiura, K; Ouchida, M; Shimizu, N; Soh, J; Suehisa, H; Toyooka, S1
Barwell, J; Donnelly, D; Garland, SL; Miller, PS; Poyner, DR; Wigglesworth, MJ1
Chang, S; Ding, J; Ding, K; Geng, M; Liu, Y; Lu, X; Luo, J; Pei, D; Ren, X; Tu, Z; Xu, S; Xu, T; Xu, Y; Zhang, L; Zhang, Z1
Amzel, LM; Bhat, S; Chen, X; Cheng, YL; Crews, P; Gabelli, SB; Liu, JO; Ma, D; Meyers, DJ; Miller, MS; Nacev, BA; Shim, JS; Tenney, K; Zhang, F1
Han, JY; Hwang, JA; Kim, HT; Kim, JH; Kim, SH; Lee, GK; Lee, JS; Lee, Y; Lee, YS; Nam, BH; Yun, T; Zhang, W1
Dai, B; Fang, B; Gao, W; Gold, KA; Heymach, JV; Hofstetter, WL; Lu, H; Minna, J; Ou, Z; Roth, JA; Swisher, SG; Wang, L; Wang, M; Wu, S; Zhang, L1
Fan, XX; Jiang, ZH; Leung, EL; Liu, L; Liu, ZQ; Lu, LL; Tin, VP; Wong, MP; Yao, XJ; Yau, LF; Zhou, YL1
Ali, SM; Busaidy, NL; Chmielecki, J; Elvin, JA; Erlich, RL; Heilmann, AM; Khan, SA; Lipson, D; Miller, VA; Murthy, R; Nangia, C; Ross, JS; Shah, MH; Sherman, SI; Stephens, PJ; Subbiah, I; Subbiah, V; Sun, JX; Vergilio, JA; Wang, K; Yelensky, R1

Reviews

1 review(s) available for quinazolines and methionine

ArticleYear
Role of epidermal growth factor receptor mutations in predicting sensitivity or resistance to targeted agents in non-small-cell lung cancer.
    Clinical lung cancer, 2005, Volume: 6, Issue:6

    Topics: Amino Acid Substitution; Antineoplastic Agents; Asian People; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Quinazolines; Sex Factors; Threonine

2005

Other Studies

10 other study(ies) available for quinazolines and methionine

ArticleYear
Carboxypeptidase G2 and trimetrexate cause growth delay of human colonic cancer cells in vitro.
    Biochemical pharmacology, 1990, Jun-01, Volume: 39, Issue:11

    Topics: Animals; Antineoplastic Agents; Carboxypeptidases; Cell Division; Colonic Neoplasms; Culture Media; Homocysteine; Humans; Methionine; Mice; Quinazolines; Rabbits; Trimetrexate; Tumor Cells, Cultured

1990
[Biosynthesis of the quinazoline alkaloid arborine].
    European journal of biochemistry, 1970, Volume: 15, Issue:3

    Topics: Alkaloids; Carbon Isotopes; Methionine; Nitrogen; ortho-Aminobenzoates; Phenylalanine; Plants; Quinazolines; Radioisotopes; Tritium

1970
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.
    Cancer research, 2006, Aug-15, Volume: 66, Issue:16

    Topics: Amino Acid Substitution; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Methionine; Mutation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Threonine

2006
Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74.
    Biochemical and biophysical research communications, 2010, Jan-01, Volume: 391, Issue:1

    Topics: Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcitonin Receptor-Like Protein; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Methionine; Piperazines; Protein Structure, Tertiary; Quinazolines; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Proteins; Receptors, Calcitonin; Tryptophan

2010
Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine⁷⁹⁰ → methionine⁷⁹⁰ mutant.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Lung Neoplasms; Methionine; Mice; Mice, Nude; Mice, SCID; Molecular Conformation; Mutation; Neoplasm Transplantation; Pyrimidines; Quinazolines; Structure-Activity Relationship; Threonine; Transplantation, Heterologous

2012
Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells.
    Journal of medicinal chemistry, 2013, May-23, Volume: 56, Issue:10

    Topics: Aminopeptidases; Animals; Cell Proliferation; Chelating Agents; Chromatography, Thin Layer; Cobalt; Crystallography, X-Ray; Down-Regulation; Enzyme Activation; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Indicators and Reagents; Manganese; Metals; Methionine; Mice; Models, Molecular; Protease Inhibitors; Pyridines; Quinazolines; RNA, Small Interfering; Thymidine; Transfection; Zinc

2013
Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations.
    Cancer, 2014, Jul-15, Volume: 120, Issue:14

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asian People; Disease-Free Survival; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Genotype; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Methionine; Middle Aged; Mutation; Neoplasm Staging; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Republic of Korea; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Treatment Outcome; Tumor Cells, Cultured

2014
Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:9

    Topics: Adenine; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Methionine; Mice; Mutation; Piperidines; Pyrazoles; Pyrimidines; Quinazolines; Threonine

2014
Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation.
    Antioxidants & redox signaling, 2016, Feb-10, Volume: 24, Issue:5

    Topics: Animals; Apoptosis; Benzophenanthridines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Gene Expression; Humans; Isoquinolines; Lung Neoplasms; Membrane Glycoproteins; Membrane Proteins; Methionine; Mice; Models, Biological; Models, Molecular; Molecular Conformation; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Protein Binding; Protein Kinase Inhibitors; Proteolysis; Quinazolines; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2016
Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.
    Oncology, 2016, Volume: 90, Issue:6

    Topics: Aged; Anilides; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Drug Resistance, Neoplasm; Everolimus; Female; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Gene Amplification; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Methionine; Middle Aged; Molecular Targeted Therapy; Mutation; Piperidines; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Pyridines; Quinazolines; Threonine; Thyroid Neoplasms

2016