Compounds > quinazolines

Page last updated: 2024-08-21

quinazolines and lysine

quinazolines has been researched along with lysine in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (18.75)	29.6817
2010's	11 (68.75)	24.3611
2020's	2 (12.50)	2.80

Authors

Authors	Studies
Brooke-Smith, M; Saccone, GT; Sandstrom, P; Svanvik, J; Toouli, J; Woods, CM	1
Brooke-Smith, ME; Grivell, MB; Saccone, GT; Sandstrom, P; Svanvik, J; Thomas, AC; Toouli, J	1
August, EM; Hickey, ER; Homon, CA; Jenuwein, T; Kelly, TA; Kowalski, JA; Kubicek, S; Mechtler, K; O'Sullivan, RJ; Rea, S; Teodoro, ML; Zhang, Q	1
Cho, S; Jeong, YS; Kang, YK; Ko, Y; Park, JS	1
Bedford, MT; Chang, Y; Cheng, X; Ganesh, T; Horton, JR; Liu, J; Shinkai, Y; Snyder, JP; Spannhoff, A; Sun, A; Zhang, X	1
Cabot, RA; Johnson, CM; Park, KE	1
Fuchter, MJ; Malmquist, NA; Mecheri, S; Moss, TA; Scherf, A	1
Itoi, F; Li, C; Sato, E; Tanemura, K; Terashita, Y; Tokoro, M; Wakayama, S; Wakayama, T; Yamagata, K	1
Feng, D; Hu, Q; Li, H; Ma, H; Su, Y; Tao, H; Wang, X; Zhang, C	1
Arihiro, K; Doi, S; Doi, T; Irifuku, T; Kohno, N; Masaki, T; Nakashima, A; Sasaki, K; Ueno, T; Yamada, K	1
Chao, SB; Huang, XJ; Lin, F; Liu, HL; Ma, XS; Meng, TG; Qin, L; Schatten, H; Sun, QY; Wang, XG; Zhu, CC	1
Huang, R; Huang, Y; Jiang, X; Li, M; Yang, X; Yao, J; Yu, M; Zheng, F	1
Chatterjee, M; Dworak, N; Jividen, K; Johnson, IG; Kelley, JB; Makosa, D; Paschal, BM; Simke, WC; Snow, C; Yang, CS	1
Damen, E; Ehlert, JE; Feger, D; Heidemann-Dinger, C; Kubbutat, M; Leenders, R; Lenstra, DC; Mecinović, J; Müller, D; Müller, G; Schächtele, C; Trivarelli, F; van Bree, B; van de Sande, M; Wegert, A; Zijlmans, R	1
López-López, E; Medina-Franco, JL; Oyarzabal, J; Rabal, O	1
Fujii, T; Hamamoto, R; Honjoh, H; Inoue, F; Kaneko, S; Kashiyama, T; Kojima, M; Komatsu, M; Kukita, A; Miyamoto, Y; Mori-Uchino, M; Osuga, Y; Sone, K; Taguchi, A; Takahashi, Y; Tanikawa, M; Tsuruga, T; Wada, M; Wada-Hiraike, O	1

Other Studies

16 other study(ies) available for quinazolines and lysine

Article	Year
Highly selective iNOS inhibition and sphincter of Oddi motility in the Australian possum. Acta physiologica Scandinavica, 2004, Volume: 181, Issue:3 Topics: Animals; Blood Pressure; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Motility; Lysine; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Opossums; Pancreas; Quinazolines; Regional Blood Flow; Sphincter of Oddi	2004
Highly selective inhibition of inducible nitric oxide synthase ameliorates experimental acute pancreatitis. Pancreas, 2005, Volume: 30, Issue:1 Topics: Acute Disease; Amino Acids; Amylases; Animals; Central Venous Pressure; Disease Models, Animal; Enzyme Inhibitors; Female; Hematocrit; Lipase; Lysine; Male; Nitric Oxide Synthase Type II; Pancreatitis; Quinazolines; Trichosurus; Water-Electrolyte Balance	2005
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Molecular cell, 2007, Feb-09, Volume: 25, Issue:3 Topics: Animals; Azepines; Cell Line; Enzyme Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Promoter Regions, Genetic; Protein Methyltransferases; Quinazolines	2007
Phosphorylation of serine-10 of histone H3 shields modified lysine-9 selectively during mitosis. Genes to cells : devoted to molecular & cellular mechanisms, 2010, Volume: 15, Issue:3 Topics: Animals; Aurora Kinase B; Benzamides; Cell Cycle; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Female; Histones; Lysine; Male; Methylation; Mice; Mitosis; NIH 3T3 Cells; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Serine	2010
Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. Journal of molecular biology, 2010, Jul-02, Volume: 400, Issue:1 Topics: Azepines; Histone Code; Histone-Lysine N-Methyltransferase; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Processing, Post-Translational; Quinazolines	2010
IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo. Reproduction, fertility, and development, 2012, Volume: 24, Issue:6 Topics: Animals; Azepines; Cleavage Stage, Ovum; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryo Transfer; Embryo, Mammalian; Embryonic Development; Enzyme Inhibitors; Female; Fertilization in Vitro; Gene Expression Regulation, Developmental; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Pregnancy; Pregnancy Rate; Quinazolines; RNA, Messenger; Swine; Time Factors; Transcription, Genetic	2012
Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America, 2012, Oct-09, Volume: 109, Issue:41 Topics: Amino Acid Sequence; Animals; Antimalarials; Azepines; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Erythrocytes; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Life Cycle Stages; Lysine; Malaria; Methylation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Quinazolines; Sequence Homology, Amino Acid	2012
Latrunculin A treatment prevents abnormal chromosome segregation for successful development of cloned embryos. PloS one, 2013, Volume: 8, Issue:10 Topics: Actins; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Chromosome Segregation; Cloning, Organism; Embryo, Mammalian; Embryonic Development; Epigenesis, Genetic; Female; Fertilization in Vitro; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nuclear Transfer Techniques; Oocytes; Quinazolines; Thiazolidines	2013
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells. Molecular and cellular biochemistry, 2014, Volume: 394, Issue:1-2 Topics: AC133 Antigen; Antigens, CD; Azepines; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplastic Stem Cells; Peptides; Promoter Regions, Genetic; Quinazolines; Signal Transduction; SOXB1 Transcription Factors; Transfection	2014
Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression. Kidney international, 2016, Volume: 89, Issue:1 Topics: Actins; Animals; Antibodies, Neutralizing; Azepines; Cell Line; Enzyme Inhibitors; Fibroblasts; Fibronectins; Fibrosis; Glomerulonephritis, IGA; Glucuronidase; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Kidney; Klotho Proteins; Lysine; Male; Methylation; Mice; Quinazolines; Rats; RNA, Messenger; RNA, Small Interfering; Transforming Growth Factor beta1; Ureteral Obstruction	2016
The Dynamics and Regulatory Mechanism of Pronuclear H3k9me2 Asymmetry in Mouse Zygotes. Scientific reports, 2015, Dec-07, Volume: 5 Topics: Animals; Azepines; Cell Nucleus; Fertilization in Vitro; Histone-Lysine N-Methyltransferase; Histones; Kruppel-Like Transcription Factors; Lysine; Methylation; Mice; Microinjections; Models, Biological; Nerve Tissue Proteins; Quinazolines; RNA, Small Interfering; Zygote	2015
Beneficial effects of diazepin-quinazolin-amine derivative (BIX-01294) on preimplantation development and molecular characteristics of cloned mouse embryos. Reproduction, fertility, and development, 2017, Volume: 29, Issue:6 Topics: Animals; Azepines; Blastocyst; Cloning, Organism; CpG Islands; DNA Methylation; Ectogenesis; Embryo, Mammalian; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; GRB10 Adaptor Protein; Histone-Lysine N-Methyltransferase; Histones; Lysine; Male; Methylation; Mice; Nuclear Transfer Techniques; Parthenogenesis; Protein Processing, Post-Translational; Quinazolines	2017
A nuclear lamina-chromatin-Ran GTPase axis modulates nuclear import and DNA damage signaling. Aging cell, 2019, Volume: 18, Issue:1 Topics: Active Transport, Cell Nucleus; Azepines; Chromatin; DNA Damage; Fibroblasts; Histones; Humans; Interphase; Lamin Type A; Lysine; Methylation; Nuclear Lamina; Progeria; Quinazolines; ran GTP-Binding Protein; Signal Transduction	2019
Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2. Bioorganic & medicinal chemistry letters, 2019, 09-01, Volume: 29, Issue:17 Topics: Binding Sites; Cell Line, Tumor; Drug Design; Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Inhibitory Concentration 50; Lysine; Molecular Docking Simulation; Pancreatic Neoplasms; Point Mutation; Quinazolines; Structure-Activity Relationship	2019
Towards the understanding of the activity of G9a inhibitors: an activity landscape and molecular modeling approach. Journal of computer-aided molecular design, 2020, Volume: 34, Issue:6 Topics: Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Lysine; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Conformation; Quinazolines; Structure-Activity Relationship	2020
Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer. Biomolecules, 2020, 12-16, Volume: 10, Issue:12 Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Inhibitory Concentration 50; Lysine; Ovarian Neoplasms; Prognosis; Quinazolines; RNA, Small Interfering; Transfection; Up-Regulation	2020