Page last updated: 2024-08-21

quinazolines and leptin

quinazolines has been researched along with leptin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitayama, J; Mori, K; Nagawa, H; Shida, D; Watanabe, T1
Ihara, S; Kawana, M; Sakai, R; Shimamoto, K; Watanabe, H1
Chao, HH; Chen, YL; Cheng, TH; Chiu, WT; Hong, HJ; Lin, JW; Liu, JC; Shyu, KG; Wu, CH1
Chen, K; Lei, Q; Shi, J; Yan, J; Yang, D; Zhang, Y; Zhao, J; Zhao, X1
Beales, IL; Ogunwobi, OO1
Anania, FA; Knight, BB; Merlin, D; O'Regan, RM; Saxena, NK; Sharma, D; Taliaferro-Smith, L1
Carvalheira, JB; Cintra, DE; de Souza, CT; Franchini, KG; MourĂ£o, RH; Pauli, JR; Prada, PO; Rittner, R; Rocco, SA; Ropelle, ER; Saad, MJ; Schenka, A; Vassallo, J; Velloso, LA1
Barry, ST; Campbell, H; Critchlow, SE; Eberlein, C; Farren, M; Frith, J; Huby, R; Kendrew, J; Michopoulos, F; Morgan, S; Patel, B; Pommier, AJ; Robertson, J; Smith, NR; Smith, PD; Wappett, M; Womack, C1

Trials

1 trial(s) available for quinazolines and leptin

ArticleYear
An alpha1-receptor blocker reduces plasma leptin levels in hypertensive patients with obesity and hyperleptinemia.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Aged; Blood Pressure; Body Mass Index; Delayed-Action Preparations; Fatty Acids, Nonesterified; Female; Heart Rate; Humans; Hypertension; Insulin Resistance; Leptin; Male; Middle Aged; Obesity; Quinazolines; Receptors, Leptin; Treatment Outcome

2006

Other Studies

7 other study(ies) available for quinazolines and leptin

ArticleYear
Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.
    Cancer research, 2005, Oct-15, Volume: 65, Issue:20

    Topics: Cell Line, Tumor; Dipeptides; ErbB Receptors; Humans; Janus Kinase 2; Leptin; MAP Kinase Signaling System; Metalloproteases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protease Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Quinazolines; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Stomach Neoplasms; Transcriptional Activation; Tyrphostins

2005
Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: Animals; Aorta, Thoracic; Blotting, Northern; Blotting, Western; Butadienes; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Endothelin-1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Leptin; Male; Metalloendopeptidases; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Signal Transduction; Transcriptional Activation; Tyrosine; Tyrphostins

2007
Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats.
    Brain research, 2009, Jan-09, Volume: 1247

    Topics: Agouti-Related Protein; Animals; Appetite Regulation; Arcuate Nucleus of Hypothalamus; Body Weight; Dose-Response Relationship, Drug; Down-Regulation; Feeding Behavior; Gene Expression Regulation; Hypothalamus; Leptin; Male; Neuropeptide Y; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger

2009
Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor.
    British journal of biomedical science, 2008, Volume: 65, Issue:3

    Topics: Adenocarcinoma; Amphiregulin; Autoantibodies; Cell Line, Tumor; Cell Proliferation; EGF Family of Proteins; ErbB Receptors; Esophageal Neoplasms; Glycoproteins; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Leptin; Matrix Metalloproteinases; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Transcriptional Activation; Transforming Growth Factor alpha; Tyrphostins

2008
Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor.
    Cancer research, 2008, Dec-01, Volume: 68, Issue:23

    Topics: Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Humans; Insulin-Like Growth Factor I; Lapatinib; Leptin; Neoplasm Invasiveness; Quinazolines; Receptor Cross-Talk; Receptor, IGF Type 1; Receptors, Leptin; Signal Transduction; Transcriptional Activation

2008
EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice.
    Diabetes, 2009, Volume: 58, Issue:12

    Topics: Adiponectin; Adipose Tissue; Animals; Blood Glucose; Dietary Fats; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Enzymologic; Glucose Tolerance Test; Hypoglycemic Agents; Immunoblotting; Immunoprecipitation; Inflammation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Leptin; Liver; Macrophages; Male; Mice; Muscle, Skeletal; NF-kappa B p50 Subunit; Nitric Oxide Synthase Type II; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; Tumor Necrosis Factor-alpha

2009
Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer.
    Cell metabolism, 2016, Jan-12, Volume: 23, Issue:1

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Body Mass Index; Cell Line, Tumor; Colorectal Neoplasms; Humans; Kaplan-Meier Estimate; Leptin; Melanoma, Experimental; Mice; Mice, Obese; Proportional Hazards Models; Quinazolines; Retrospective Studies; Transcriptome; Treatment Outcome; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2016