quinazolines has been researched along with l 2286 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartha, E; Czopf, L; Deres, P; Halmosi, R; Hantó, K; Hideg, K; Kálai, T; Kulcsár, G; Pálfi, A; Sümegi, B; Szabados, E; Tóth, A; Tóth, K | 1 |
| Deres, P; Gallyas, F; Halmosi, R; Hanto, K; Hideg, K; Kalai, T; Kulcsar, G; Palfi, A; Sumegi, B; Szabados, E; Szereday, Z; Toth, A; Toth, K | 1 |
| Bartha, E; Habon, T; Halmosi, R; Hideg, K; Kálai, T; Kalman, E; Kiss, GN; Kulcsár, G; Sumegi, B; Toth, K | 1 |
| Bartha, E; Halmosi, R; Hideg, K; Kálai, T; Kereskai, L; Lantos, J; Magyar, K; Plozer, E; Solti, I; Sumegi, B; Szabados, E; Toth, K | 1 |
| Besson, V; Büki, A; Bukovics, P; Dóczi, T; Hernádi, I; Kövesdi, E; Lückl, J; Nyirádi, J; Pál, J; Sümegi, B | 1 |
| Bartha, E; Gero, D; Halmosi, R; Hideg, K; Kalai, T; Magyar, K; Olah, G; Solti, I; Sumegi, B; Szabados, E; Szabo, A; Szabo, C; Toth, K | 1 |
| Balogh, A; Bruszt, K; Deres, L; Eros, K; Gallyas, F; Halmosi, R; Hamar, J; Hideg, K; Magyar, K; Seress, L; Sumegi, B; Toth, K | 1 |
| Bartha, E; Deres, L; Eros, K; Gallyas, F; Halmosi, R; Hideg, K; Kalai, T; Lantos, J; Palfi, A; Riba, A; Sumegi, B; Toth, K | 1 |
| Deres, L; Eros, K; Gallyas, F; Halmosi, R; Kalai, T; Magyar, K; Riba, A; Skazel, A; Sumegi, B; Toth, K; Vamos, Z | 1 |
| Bruszt, K; Deres, L; Eros, K; Gallyas, F; Halmosi, R; Horvath, O; Kalman, N; Kovacs, D; Ordog, K; Radnai, B; Toth, K; Toth, S | 1 |
10 other study(ies) available for quinazolines and l 2286
| Article | Year |
|---|---|
The role of Akt and mitogen-activated protein kinase systems in the protective effect of poly(ADP-ribose) polymerase inhibition in Langendorff perfused and in isoproterenol-damaged rat hearts.
Topics: Animals; Energy Metabolism; Enzyme Inhibitors; Heart; Hydrogen Peroxide; Isoproterenol; Lipid Peroxidation; Male; Mitogen-Activated Protein Kinases; Myocardium; Perfusion; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Protective Agents; Proteins; Quinazolines; Rats; Rats, Sprague-Dawley | 2005 |
PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway.
Topics: Animals; Cardiomegaly; Collagen Type III; Electrocardiography; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Failure; Isoproterenol; Male; Mitogen-Activated Protein Kinases; Myocardial Infarction; Natriuretic Peptide, Brain; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventricular Remodeling | 2006 |
Effect of L-2286, a poly(ADP-ribose)polymerase inhibitor and enalapril on myocardial remodeling and heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Disease Models, Animal; Echocardiography; Enalapril; Enzyme Inhibitors; Fibrosis; Heart Failure; Male; Myocardial Infarction; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventricular Remodeling | 2008 |
PARP inhibition delays transition of hypertensive cardiopathy to heart failure in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Blood Pressure; Cardiovascular Agents; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Male; Myocardium; Natriuretic Peptide, Brain; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Inbred SHR; Signal Transduction; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2009 |
A novel PARP inhibitor L-2286 in a rat model of impact acceleration head injury: an immunohistochemical and behavioral study.
Topics: Animals; Anxiety; Axons; Behavior, Animal; Brain Injuries; Disease Models, Animal; Enzyme Inhibitors; Immunohistochemistry; Infusions, Intraventricular; Male; Neuroprotective Agents; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinazolines; Rats; Rats, Wistar | 2010 |
Regulation of kinase cascade activation and heat shock protein expression by poly(ADP-ribose) polymerase inhibition in doxorubicin-induced heart failure.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Heart Failure; HSP72 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Male; MAP Kinase Signaling System; Mice; Myocytes, Cardiac; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Rats; Spin Labels | 2011 |
A quinazoline-derivative compound with PARP inhibitory effect suppresses hypertension-induced vascular alterations in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Cell Death; Collagen; Hypertension; Male; Mitochondria; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinase; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Inbred SHR; Rats, Wistar; Signal Transduction | 2014 |
PARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms.
Topics: Animals; Blood Pressure; Extracellular Signal-Regulated MAP Kinases; Forkhead Transcription Factors; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Failure; HSP90 Heat-Shock Proteins; Hypertension; Hypertrophy, Left Ventricular; Isoenzymes; Male; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction | 2014 |
Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Carotid Arteries; Hippocampus; Hypertension; Male; Oxidative Stress; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Remodeling | 2017 |
Mitochondrial protective effects of PARP-inhibition in hypertension-induced myocardial remodeling and in stressed cardiomyocytes.
Topics: Animals; Cells, Cultured; Citrate (si)-Synthase; DNA, Mitochondrial; Electrocardiography; Glutathione; Hypertension; Hypertrophy, Left Ventricular; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Proteins; Myocytes, Cardiac; Natriuretic Peptide, Brain; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Rats, Inbred SHR; Rats, Wistar | 2021 |