quinazolines has been researched along with krn 633 in 17 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (5.88) | 29.6817 |
2010's | 13 (76.47) | 24.3611 |
2020's | 3 (17.65) | 2.80 |
Authors | Studies |
---|---|
Matsunaga, N; Nakamura, K; Taguchi, E; Takahashi, K; Tsunoda, H; Yamamoto, A | 1 |
Abe, N; Ishii, K; Nagamitsu, T; Nakahara, T; Ohta, H; Ozaki, H; Wada, Y | 1 |
Ban, HS; Nakamura, H; Uno, M | 1 |
Abe, N; Ishii, K; Mori, A; Nagamitsu, T; Nakahara, T; Ozaki, H; Sakamoto, K; Wada, Y | 1 |
Abe, N; Ishii, K; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K; Wada, Y | 1 |
Abe, N; Ishii, K; Kurauchi, Y; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K | 2 |
Asano, D; Ishii, K; Mori, A; Nakahara, T; Sakamoto, K | 1 |
Ishii, K; Mori, A; Nakahara, T; Sakamoto, K; Yagasaki, R | 1 |
Ishii, K; Mori, A; Nakahara, T; Nakano, A; Sakamoto, K; Ushikubo, H | 1 |
Arima, S; Ishii, K; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K; Ushikubo, H | 1 |
Arima, S; Ishii, K; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K | 1 |
Arima, S; Asano, D; Ishii, K; Kondo, R; Mori, A; Nagamitsu, T; Nakahara, T; Nakano, A; Sakamoto, K; Ushikubo, H | 1 |
Arima, S; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K; Sawada, S | 1 |
Arima, S; Asano, D; Kaneko, Y; Kondo, R; Morita, A; Nagamitsu, T; Nakahara, T; Nakano, A; Sakamoto, K | 1 |
Arima, S; Asano, D; Kondo, R; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Nakano, A; Sakamoto, K | 1 |
Arima, S; Mori, A; Morita, A; Nagamitsu, T; Nakahara, T; Sakamoto, K; Yoshizumi, M | 1 |
17 other study(ies) available for quinazolines and krn 633
Article | Year |
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Improvement by solid dispersion of the bioavailability of KRN633, a selective inhibitor of VEGF receptor-2 tyrosine kinase, and identification of its potential therapeutic window.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood Vessels; Body Weight; Crystallization; Drug Compounding; Drug Stability; Humans; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Phenylurea Compounds; Quinazolines; Rats; Rats, Sprague-Dawley; Solubility; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2006 |
Effects of KRN633, an inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase, on vascular development of placenta and fetus of mid-pregnancy in mice.
Topics: Animals; Female; Fetal Growth Retardation; Fetus; Mice; Mice, Inbred ICR; Phenylurea Compounds; Placenta; Pregnancy; Pregnancy Trimester, Second; Protein Kinase Inhibitors; Quinazolines; Vascular Endothelial Growth Factor Receptor-2 | 2010 |
Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633.
Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Line, Tumor; Colorectal Neoplasms; DNA Primers; DNA-Directed DNA Polymerase; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; HeLa Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Indoles; Phenylurea Compounds; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Vascular Endothelial Growth Factor A | 2010 |
Role of vascular endothelial growth factor in maintenance of pregnancy in mice.
Topics: Animals; Corpus Luteum; Female; Mice; Mice, Inbred ICR; Parturition; Phenylurea Compounds; Pregnancy; Progesterone; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A | 2013 |
KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces intrauterine growth restriction in mice.
Topics: Animals; Animals, Newborn; Female; Fetal Growth Retardation; Intestine, Small; Kidney; Lymphoid Tissue; Male; Mice; Pancreas; Phenylurea Compounds; Placenta; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Receptors, Vascular Endothelial Growth Factor | 2013 |
Effects of pre- and post-natal treatment with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, on retinal vascular development and patterning in mice.
Topics: Administration, Oral; Animals; Animals, Newborn; Female; Fluorescein Angiography; Fluorescent Antibody Technique, Indirect; In Situ Hybridization; Male; Mice; Mice, Inbred ICR; Phenylurea Compounds; Platelet Endothelial Cell Adhesion Molecule-1; Pregnancy; Prenatal Exposure Delayed Effects; Quinazolines; Retinal Neovascularization; Retinal Vessels; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
Treatment of mid-pregnant mice with KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces abnormal retinal vascular patterning in their newborn pups.
Topics: Animals; Animals, Newborn; Female; Fetal Growth Retardation; Mice; Mice, Inbred ICR; Neovascularization, Physiologic; Phenylurea Compounds; Pregnancy; Quinazolines; Receptor, Platelet-Derived Growth Factor beta; Receptors, Vascular Endothelial Growth Factor; Retinal Vessels | 2014 |
Regression of retinal capillaries following N-methyl-D-aspartate-induced neurotoxicity in the neonatal rat retina.
Topics: Age Factors; Animals; Animals, Newborn; Capillaries; Collagen Type IV; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Male; N-Methylaspartate; Neurotoxicity Syndromes; Phenylurea Compounds; Plant Lectins; Quinazolines; Rats; Rats, Sprague-Dawley; Rec A Recombinases; Retinal Degeneration; Statistics, Nonparametric; Vascular Endothelial Growth Factor A | 2015 |
Effects of mTOR inhibition on normal retinal vascular development in the mouse.
Topics: Animals; Cell Count; Cell Growth Processes; Endothelium, Vascular; Female; Male; Mice; Phenylurea Compounds; Quinazolines; Retinal Vessels; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Short-term treatment with VEGF receptor inhibitors induces retinopathy of prematurity-like abnormal vascular growth in neonatal rats.
Topics: Animals; Animals, Newborn; Axitinib; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Imidazoles; Indazoles; Microscopy, Fluorescence; Phenylurea Compounds; Pregnancy; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinal Vessels; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
A delay in vascularization induces abnormal astrocyte proliferation and migration in the mouse retina.
Topics: Animals; Astrocytes; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Hypoxia; Immunohistochemistry; In Situ Hybridization; Male; Mice; Phenylurea Compounds; Pregnancy; Quinazolines; Retina; Vascular Endothelial Growth Factor A | 2017 |
Transient phenotypic changes in endothelial cells and pericytes in neonatal mouse retina following short-term blockade of vascular endothelial growth factor receptors.
Topics: Animals; Animals, Newborn; Cell Proliferation; Female; Immunohistochemistry; Male; Mice; Pericytes; Phenylurea Compounds; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Retina; Vascular Endothelial Growth Factor A | 2018 |
Retinal neuronal cell loss prevents abnormal retinal vascular growth in a rat model of retinopathy of prematurity.
Topics: Animals; Capillaries; Cell Proliferation; Disease Models, Animal; N-Methylaspartate; Phenylurea Compounds; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Retinal Neurons; Retinal Vessels; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A | 2018 |
Establishment of an abnormal vascular patterning model in the mouse retina.
Topics: Animals; Animals, Newborn; Choroid; Disease Models, Animal; Electroretinography; Female; Ischemia; Male; Mice, Inbred ICR; Phenylurea Compounds; Quinazolines; Retina; Retinal Vessels; Signal Transduction; Time Factors; Vascular Endothelial Growth Factor A | 2018 |
Changes in components of the neurovascular unit in the retina in a rat model of retinopathy of prematurity.
Topics: Animals; Disease Models, Animal; Female; Phenylurea Compounds; Pregnancy; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Retina; Retinal Neovascularization; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A | 2020 |
Abnormal Vascular Phenotypes Associated with the Timing of Interruption of Retinal Vascular Development in Rats.
Topics: Animals; Animals, Newborn; Phenotype; Phenylurea Compounds; Protein Kinase Inhibitors; Quinazolines; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; Retinal Vessels; Time Factors | 2020 |
Pharmacological depletion of retinal neurons prevents vertical angiogenic sprouting without affecting the superficial vascular plexus.
Topics: Animals; Astrocytes; Female; Male; Mice, Inbred ICR; N-Methylaspartate; Neovascularization, Physiologic; Phenylurea Compounds; Quinazolines; Retina | 2021 |