quinazolines has been researched along with jrf 12 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (92.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, SJ; Chase, P; Chou, TF; Deshaies, RJ; Hodder, P; Jones, AC; Li, K; Minond, D; Nordin, BE; Patricelli, MP; Porubsky, PR; Rosen, H; Schoenen, FJ; Stoltz, BM | 1 |
| Chou, TF; Deshaies, RJ | 1 |
| Beauparlant, SL; den Besten, W; Deshaies, RJ; Graham, RL; Haines, DS; Hess, S; Kyle, DB; Lee, JE; Sweredoski, MJ | 1 |
| Arma, D; Balabaud, C; Bexiga, MG; Bioulac-Sage, P; Blanc, JF; Castain, C; Chevet, E; Higa, A; Le Bail, B; Marza, E; Rosenbaum, J; Simpson, JC; Taouji, S; Yi, P | 1 |
| Dolan, BP; Palmer, AL | 1 |
| Chou, TF; Fang, CJ; Frankowski, KJ; Gui, L; Li, K; Lin, HJ; Moen, DR; Schoenen, FJ; Zhang, X | 1 |
| Hao, Q; Jiao, S; Li, C; Shi, Z; Song, X; Wang, W; Wang, Y; Zhang, Z; Zhao, Y; Zhou, Z | 1 |
| Bulawa, CE; Gooch, RL; Nabhan, JF; Piatnitski Chekler, EL; Pierce, B | 1 |
| Chen, H; Chu, M; Fang, C; Li, W; Luo, K; Luo, T; She, X; Sun, N; Wang, Q; Yang, D; Yu, H; Zhang, M; Zhang, Y | 1 |
| Bodas, M; Campbell, RJ; Sharma, A; Swanson, D; Vij, N; Walworth, K | 1 |
| Bastola, P; Chien, J; Neums, L; Schoenen, FJ | 1 |
| He, J; Wani, AA; Wani, G; Zhu, Q | 1 |
| Chen, J; Gao, Y; Huo, J; Peng, H; Wang, C; Xiao, T; Zhang, Y | 1 |
| Cayli, S; Desdicioglu, R; Sahin, C; Yavuz, F | 1 |
14 other study(ies) available for quinazolines and jrf 12
| Article | Year |
|---|---|
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Autophagy; Caspase 3; Caspase 7; Cell Line; Endoplasmic Reticulum; Enzyme Inhibitors; Humans; Mice; Neoplasms; Nuclear Proteins; Proteasome Endopeptidase Complex; Quinazolines; Ubiquitin | 2011 |
Development of p97 AAA ATPase inhibitors.
Topics: Adenosine Triphosphatases; Animals; Caspase 3; Caspase 7; Endoplasmic Reticulum-Associated Degradation; Enzyme Inhibitors; HeLa Cells; Humans; Models, Biological; Nuclear Proteins; Proteasome Endopeptidase Complex; Quinazolines; Structure-Activity Relationship; Ubiquitin | 2011 |
Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adenosine Triphosphatases; Autophagy-Related Proteins; Benzoates; Carrier Proteins; Cell Line, Tumor; Furans; Humans; Mannose-Binding Lectins; Membrane Proteins; Nuclear Proteins; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Mapping; Protein Transport; Pyrazoles; Quinazolines; rab3 GTP-Binding Proteins; Secretory Vesicles; Ubiquitin-Activating Enzymes | 2012 |
Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death.
Topics: Adenosine Triphosphatases; Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Secretory Pathway; Sorafenib | 2012 |
MHC class I antigen presentation of DRiP-derived peptides from a model antigen is not dependent on the AAA ATPase p97.
Topics: Adenosine Triphosphatases; Animals; Antigen Presentation; Antigens; Blotting, Western; Cell Line; Cell Line, Tumor; Female; Flow Cytometry; Histocompatibility Antigens Class I; Humans; Mice; Nuclear Proteins; Peptide Biosynthesis; Peptide Fragments; Polyubiquitin; Quinazolines; Recombinant Fusion Proteins; Ribosomes; Signal Transduction; Thy-1 Antigens; Ubiquitinated Proteins | 2013 |
Evaluating p97 inhibitor analogues for their domain selectivity and potency against the p97-p47 complex.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Antineoplastic Agents; Benzimidazoles; Benzoxazines; Enzyme Inhibitors; Humans; Mutation; Nuclear Proteins; Protein Binding; Protein Structure, Tertiary; Quinazolines; Structure-Activity Relationship | 2015 |
The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-κB Signaling via Partial Degradation of the NF-κB Subunit p100.
Topics: Adaptor Proteins, Vesicular Transport; Animals; beta Karyopherins; Cell Line, Tumor; Endoplasmic Reticulum; Fibroblasts; Gene Expression Regulation; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Lung; Lymphocytes; Male; Mice; Mice, Knockout; NF-kappa B p52 Subunit; Nuclear Proteins; Pneumonia; Proteasome Endopeptidase Complex; Proteins; Proteolysis; Quinazolines; Signal Transduction; SKP Cullin F-Box Protein Ligases; Transcription, Genetic; Ubiquitination | 2015 |
Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin.
Topics: Adenosine Triphosphatases; Cell Cycle Proteins; Cell Line; Frataxin; Friedreich Ataxia; Humans; Iron-Binding Proteins; Membrane Potential, Mitochondrial; Mitochondrial Proteins; Proteasome Endopeptidase Complex; Protein Interaction Maps; Protein Precursors; Protein Processing, Post-Translational; Proteolysis; Quinazolines; Signal Transduction; Trinucleotide Repeat Expansion; Ubiquitin; Valosin Containing Protein | 2015 |
The AAA ATPase Vps4 Plays Important Roles in Candida albicans Hyphal Formation and is Inhibited by DBeQ.
Topics: Adenosine Triphosphatases; Candida albicans; Endosomal Sorting Complexes Required for Transport; Enzyme Inhibitors; Fungal Proteins; Gene Deletion; Humans; Hydrogen-Ion Concentration; Hyphae; Inhibitory Concentration 50; Quinazolines; Virulence Factors | 2016 |
Dendrimer-Based Selective Proteostasis-Inhibition Strategy to Control NSCLC Growth and Progression.
Topics: Adenosine Triphosphatases; Antineoplastic Agents; Apoptosis; Bronchi; Caspase 3; Caspase 7; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dendrimers; Drug Carriers; Drug Compounding; Enzyme Inhibitors; Epithelial Cells; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Proteolysis; Quinazolines; Receptors, Peptide; Ubiquitinated Proteins; Valosin Containing Protein | 2016 |
VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal.
Topics: Adenosine Triphosphatases; Antineoplastic Agents; Benzimidazoles; Caspases; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cinnamates; Drug Synergism; Endoplasmic Reticulum Stress; Female; Humans; Ovarian Neoplasms; Ovary; Quinazolines; Thiourea; Valosin Containing Protein | 2016 |
UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adenosine Triphosphatases; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Survival; DNA Helicases; DNA Repair Enzymes; HCT116 Cells; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Poly-ADP-Ribose Binding Proteins; Proteins; Proteolysis; Quinazolines; RNA Interference; RNA Polymerase II; Time Factors; Ubiquitination; Ultraviolet Rays; Valosin Containing Protein; Von Hippel-Lindau Tumor Suppressor Protein | 2017 |
Valosin-containing protein is associated with maintenance of meiotic arrest in mouse oocytes†.
Topics: Animals; Cell Cycle Checkpoints; Cells, Cultured; Embryo, Mammalian; Female; Male; Meiosis; Mice; Mice, Inbred ICR; Oocytes; Quinazolines; Resting Phase, Cell Cycle; Valosin Containing Protein | 2019 |
Disruption of p97/VCP induces autophagosome accumulation, cell cycle arrest and apoptosis in human choriocarcinoma cells.
Topics: Apoptosis; Autophagosomes; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choriocarcinoma; G1 Phase; Humans; Microtubule-Associated Proteins; Polyubiquitin; Quinazolines; Resting Phase, Cell Cycle; RNA, Small Interfering; Sequestosome-1 Protein; Ubiquitination; Valosin Containing Protein | 2021 |