Page last updated: 2024-08-21

quinazolines and isaindigotone

quinazolines has been researched along with isaindigotone in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alcaraz, MJ; Gonzalez-Tejero, A; Molina, P; Rioja, I; Tárraga, A; Terencio, MC; Ubeda, A1
Baldino, CM; Liu, JF; Ng, SC; Sargent, K; Sprague, K; Wilson, CJ; Ye, P; Yohannes, D1
Gu, LQ; Hou, JQ; Huang, SL; Huang, ZS; Pan, L; Tan, JH1
Gu, LQ; Hou, JQ; Huang, SL; Huang, ZS; Lu, YJ; Luo, HB; Ou, TM; Tan, JH; Wong, KY; Wu, JY1
Chen, SB; Chen, SH; Gu, LQ; Hou, JQ; Huang, SY; Huang, ZS; Li, D; Luo, HB; Ou, TM; Tan, JH; Wang, XX; Yan, JW1
Chen, SB; Gu, LQ; Hou, JQ; Huang, ZS; Li, D; Li, YP; Ou, TM; Tan, JH; Yan, JW; Ye, WJ1
Chen, SB; Gu, LQ; Hou, JQ; Huang, ZS; Li, D; Ou, TM; Tan, JH; Wu, WB; Yan, JW; Ye, WJ1
Chen, SB; Gu, LQ; Huang, ZS; Li, D; Liu, HY; Ou, TM; Tan, JH; Yan, JW; Ye, WJ1
Che, T; Chen, AC; Gu, LQ; Huang, ZL; Huang, ZS; Li, D; Ou, TM; Shan, C; Tan, JH; Wang, YQ; Yan, JW; Yao, PF1
Xiao, H; Xu, J1
Chen, SB; Guo, QL; Huang, SL; Huang, ZS; Li, D; Ou, TM; Tan, JH; Wang, CX; Wang, HG; Wang, YQ; Yin, QK; Zhang, ZL1

Other Studies

11 other study(ies) available for quinazolines and isaindigotone

ArticleYear
Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives.
    Journal of natural products, 2001, Volume: 64, Issue:10

    Topics: Alkaloids; Animals; Brassicaceae; Cells, Cultured; Chromatography, Thin Layer; Dinoprostone; Free Radical Scavengers; Humans; Inflammation; Inflammation Mediators; Inhibitory Concentration 50; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Neutrophils; Nitric Oxide Synthase; Plants, Medicinal; Quinazolines; Structure-Activity Relationship; Xanthine Oxidase

2001
Novel one-pot total syntheses of deoxyvasicinone, mackinazolinone, isaindigotone, and their derivatives promoted by microwave irradiation.
    Organic letters, 2005, Jul-21, Volume: 7, Issue:15

    Topics: Alkaloids; Microwaves; Molecular Structure; Quinazolines; Quinazolinones; Radiation

2005
Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
    Bioorganic & medicinal chemistry letters, 2008, Jul-01, Volume: 18, Issue:13

    Topics: Acetylcholinesterase; Alkaloids; Binding Sites; Butyrylcholinesterase; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Drug Design; Enzyme Inhibitors; Humans; Models, Chemical; Molecular Conformation; Molecular Structure; Quinazolines; Structure-Activity Relationship

2008
Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Alkaloids; Analysis of Variance; Cell Line, Tumor; Cellular Senescence; Circular Dichroism; DNA; Enzyme Inhibitors; Fluorescence; Fluorescence Resonance Energy Transfer; G-Quadruplexes; Humans; Ligands; Models, Molecular; Molecular Conformation; Quinazolines; Substrate Specificity; Telomerase; Telomere; Titrimetry; Transition Temperature

2009
Impact of planarity of unfused aromatic molecules on G-quadruplex binding: learning from isaindigotone derivatives.
    Organic & biomolecular chemistry, 2011, Sep-21, Volume: 9, Issue:18

    Topics: Alkaloids; Binding Sites; Circular Dichroism; DNA; Fluorescence Resonance Energy Transfer; G-Quadruplexes; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Quinazolines

2011
Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation.
    Bioorganic & medicinal chemistry, 2012, Apr-15, Volume: 20, Issue:8

    Topics: Acetylcholinesterase; Alkaloids; Amyloid beta-Peptides; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Electrophorus; Horses; Models, Molecular; Molecular Structure; Protein Binding; Quinazolines; Stereoisomerism; Structure-Activity Relationship

2012
Development of a universal colorimetric indicator for G-quadruplex structures by the fusion of thiazole orange and isaindigotone skeleton.
    Analytical chemistry, 2012, Aug-07, Volume: 84, Issue:15

    Topics: Alkaloids; Benzothiazoles; Colorimetry; Fluorescence Resonance Energy Transfer; G-Quadruplexes; Indicators and Reagents; Quinazolines; Quinolines

2012
Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids.
    Chemical communications (Cambridge, England), 2014, Jul-04, Volume: 50, Issue:52

    Topics: Alkaloids; Colorimetry; DNA; DNA, Ribosomal; Fluorescent Dyes; G-Quadruplexes; HeLa Cells; Humans; Indicators and Reagents; Lung Neoplasms; Molecular Structure; Nucleolin; Phosphoproteins; Quinazolines; RNA-Binding Proteins; Spectrometry, Fluorescence

2014
Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate c-myc Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex.
    Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4

    Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Down-Regulation; Drug Design; Female; G-Quadruplexes; Gene Expression Regulation, Neoplastic; Humans; NM23 Nucleoside Diphosphate Kinases; Proto-Oncogene Proteins c-myc; Quinazolines; Transcription, Genetic; Transcriptional Activation; Uterine Cervical Neoplasms

2017
Isaindigotone as an inhibitor of the lipopolysaccharide‑induced inflammatory reaction of BV‑2 cells and corresponding mechanisms.
    Molecular medicine reports, 2019, Volume: 19, Issue:4

    Topics: Alkaloids; Anti-Inflammatory Agents; Cell Line; Cytokines; Drugs, Chinese Herbal; Inflammation; Inflammation Mediators; Lipopolysaccharides; Microglia; NF-kappa B; Quinazolines; Signal Transduction

2019
Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair.
    Journal of medicinal chemistry, 2019, 03-28, Volume: 62, Issue:6

    Topics: Alkaloids; Apoptosis; Cell Proliferation; DNA; DNA Breaks, Double-Stranded; Drug Discovery; Enzyme Inhibitors; HCT116 Cells; Humans; Quinazolines; Rad51 Recombinase; Recombinational DNA Repair; RecQ Helicases

2019