Page last updated: 2024-08-21

quinazolines and interleukin-8

quinazolines has been researched along with interleukin-8 in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (48.57)29.6817
2010's15 (42.86)24.3611
2020's3 (8.57)2.80

Authors

AuthorsStudies
Devlin, RB; Ghio, AJ; Samet, JM; Wu, W1
Keates, AC; Keates, S; Kelly, CP; Peek, RM; Shaw, LM; Sougioultzis, S; Zhao, D1
Hirata, A; Kometani, T; Kuwano, M; Kuwano, T; Naito, S; Ogawa, S; Ono, M1
Prydz, H; Wiiger, MT1
Adachi, T; Chihara, J; Cui, CH; Kanda, A; Kayaba, H; Ohta, K1
Banasik, M; Dytnerska, K; Lewkowicz, N; Lewkowicz, P; Tchórzewski, H1
Kishida, O; Kiyohara, T; Miyazaki, T; Miyazaki, Y; Murayama, Y; Ogasa, M; Shimomura, I; Shinomura, Y; Tsutsui, S; Watabe, K; Yamamoto, T2
Higashiyama, S; Itoh, M; Joh, T; Kataoka, H; Nakao, H; Ohhara, H; Ohshima, T; Sasaki, M; Tanida, S; Watanabe, K1
Kitayama, J; Mori, K; Nagawa, H; Shida, D; Watanabe, T; Yamashita, H1
Chokki, M; Kamimura, T; Mitsuhashi, H1
Fukuda, Y; Goto, M; Terakawa, M; Tomimori, Y1
Augé, JM; Ayuso, C; Cajal, R; Conill, C; Fernández-Cruz, L; Gallego, R; Gascón, P; Ginès, A; Marmol, M; Martin-Richard, M; Maurel, J; Miquel, R; Nadal, C; Navarro, S; Petriz, L; Sánchez, M1
Hashizume, H; Kamio, N; Matsushima, K; Nakao, S; Sugiya, H1
Boichot, E; Gillon, JY; Guénon, I; Lagente, V; Le Quément, C1
Channon, JY; Coutermarsh, B; Stanton, BA; Talebian, L1
Arroyo, R; Cervantes-Sandoval, I; Meza-Cervantez, P; Serrano-Luna, JJ; Shibayama, M; Tsutsumi, V1
Capó-Aponte, JE; Pan, Z; Reinach, PS; Wang, Z; Yang, H; Zhang, F1
Maffei, VJ; Newton-West, M; Swerlick, RA; White, KJ1
Band, H; Dodmane, PR; Heires, AJ; Romberger, DJ; Schulte, NA; Toews, ML1
Li, Y; Wang, H; Xia, Y; Xu, W; Yan, J1
Barnes, PJ; Ito, K; Ito, M; Osoata, G; Rossios, C; To, Y1
Beck, PL; Buret, A; Hirota, CL; Hollenberg, MD; Jijon, HB1
Hirata, K; Kimura, T; Kira, Y; Kudoh, S; Matsuura, K; Mitsuoka, S; Nagata, M; Nakai, T; Oka, T; Suzumura, T; Umekawa, K; Yoshimura, N1
Liu, Y; Shi, HL; Wu, XJ; Xie, JQ1
Chang, CM; Chang, WC; Chuang, HY; Hou, MF; Lee, YC; Lin, YC; Tsai, YT; Wang, JY; Wei, PL; Wong, JH1
Chen, C; Cretoiu, SM; Shi, L; Wang, B; Wang, L; Wang, Q; Wang, X1
Ballon-Landa, E; Galen, B; Kalinowski, A; Knoff, D; Koff, JL; Lanier, LL; Min-Oo, G; Nadel, JA; Ueki, I1
Ahmadiiveli, A; Carson, DA; Chan, M; Corr, M; Cottam, HB; Crain, B; Hayashi, T; Kouznetsova, VL; Messer, K; Nour, A; Pu, M; Tawatao, RI; Tsigelny, IF; Yao, S1
David, JM; Dominguez, C; Fernando, RI; Hamilton, DH; McCampbell, KK; Palena, C1
Jin, DY; Lou, WH; Rong, YF; Wu, W; Xu, XF; Zhang, L1
Brands, RC; El-Mesery, M; Hartmann, S; Kübler, AC; Müller-Richter, UDA; Scheurer, MJJ; Seher, A1
Furue, K; Furue, M; Ito, T; Nakahara, T; Tsuji, G1
Kim, JB; Kim, SH; Lee, P; Yang, JY1
Cao, W; De La Cruz, JA; Diebold, BA; Ganesh, T; Gangappa, S; Hofstetter, A; Kumar, A; Lambeth, JD; McCoy, J; Ranjan, P; Sambhara, S; Singh, N; Smith, SME1

Trials

1 trial(s) available for quinazolines and interleukin-8

ArticleYear
Phase I trial of gefitinib with concurrent radiotherapy and fixed 2-h gemcitabine infusion, in locally advanced pancreatic cancer.
    International journal of radiation oncology, biology, physics, 2006, Dec-01, Volume: 66, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Drug Administration Schedule; Feasibility Studies; Female; Gefitinib; Gemcitabine; Humans; Interleukin-8; Male; Middle Aged; Pancreatic Neoplasms; Quinazolines; Radiotherapy Dosage; Vascular Endothelial Growth Factor A

2006

Other Studies

34 other study(ies) available for quinazolines and interleukin-8

ArticleYear
Activation of the EGF receptor signaling pathway in airway epithelial cells exposed to Utah Valley PM.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:2

    Topics: Air Pollutants, Occupational; Bronchi; Cells, Cultured; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Interleukin-8; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Metallurgy; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinazolines; Respiratory Mucosa; RNA, Messenger; Signal Transduction; Tyrphostins; Utah

2001
cag+ Helicobacter pylori induce transactivation of the epidermal growth factor receptor in AGS gastric epithelial cells.
    The Journal of biological chemistry, 2001, Dec-21, Volume: 276, Issue:51

    Topics: Antigens, Bacterial; Bacterial Proteins; Cell Line; Enzyme Activation; Epithelial Cells; ErbB Receptors; Gastric Mucosa; Gene Expression Regulation, Bacterial; Helicobacter pylori; Humans; Interleukin-8; Mitogen-Activated Protein Kinases; Phosphorylation; Quinazolines; Transcriptional Activation; Tyrphostins

2001
ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase.
    Cancer research, 2002, May-01, Volume: 62, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Squamous Cell; Cell Movement; Cells, Cultured; Cornea; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Gefitinib; Humans; Interleukin-8; Lymphokines; Male; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Physiologic; Quinazolines; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vulvar Neoplasms

2002
The epidermal growth factor receptor (EGFR) and proline rich tyrosine kinase 2 (PYK2) are involved in tissue factor dependent factor VIIa signalling in HaCaT cells.
    Thrombosis and haemostasis, 2004, Volume: 92, Issue:1

    Topics: Binding Sites; Cell Line; DNA-Binding Proteins; Early Growth Response Protein 1; Epidermal Growth Factor; ErbB Receptors; Factor VIIa; Focal Adhesion Kinase 2; Heparin-binding EGF-like Growth Factor; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Interleukin-8; Keratinocytes; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Recombinant Proteins; RNA, Messenger; Signal Transduction; Thromboplastin; Transcription Factors; Tyrphostins

2004
Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells.
    Biochemical and biophysical research communications, 2004, Jul-23, Volume: 320, Issue:2

    Topics: Bronchi; Cell Line; Chemokine CCL11; Chemokines, CC; Epithelial Cells; ErbB Receptors; Humans; Interleukin-8; Phosphorylation; Quinazolines; Receptor Cross-Talk; Receptors, CCR3; Receptors, Chemokine; Signal Transduction; Tyrosine; Tyrphostins

2004
Epidermal growth factor enhances TNF-alpha-induced priming of human neutrophils.
    Immunology letters, 2005, Jan-31, Volume: 96, Issue:2

    Topics: CD11b Antigen; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Humans; Inflammation; Interleukin-8; Neutrophils; Phagocytosis; Protein Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Respiratory Burst; Tumor Necrosis Factor-alpha; Tyrphostins

2005
Gefitinib (Iressa, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:6

    Topics: Amphiregulin; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Drug Screening Assays, Antitumor; EGF Family of Proteins; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Glycoproteins; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Irinotecan; Phosphorylation; Quinazolines; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms; Transforming Growth Factor alpha; Tyrosine

2005
Gefitinib ("Iressa", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:4

    Topics: Adenocarcinoma; Amphiregulin; Antineoplastic Agents; Camptothecin; EGF Family of Proteins; ErbB Receptors; Gefitinib; Glycoproteins; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Irinotecan; Metalloproteases; Phosphorylation; Quinazolines; Reactive Oxygen Species; Stomach Neoplasms; Transforming Growth Factor alpha; Tumor Cells, Cultured

2005
Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:11

    Topics: ADAM Proteins; Cell Line, Tumor; Cell Proliferation; DNA; Enzyme Activation; ErbB Receptors; Flavonoids; Glycine; Helicobacter pylori; Humans; Hydroxamic Acids; Interleukin-8; MAP Kinase Kinase 1; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Transcriptional Activation; Tyrphostins

2005
Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.
    The Journal of surgical research, 2006, Volume: 132, Issue:1

    Topics: Cell Line, Tumor; Chemotaxis; Colonic Neoplasms; Dipeptides; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Humans; Interleukin-8; Lysophospholipids; Phosphorylation; Phosphotyrosine; Protease Inhibitors; Quinazolines; Transcriptional Activation; Tyrphostins

2006
Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor-alpha-induced IL-8 secretion in the human airway epithelial cell line NCI-H292.
    Life sciences, 2006, May-22, Volume: 78, Issue:26

    Topics: Amphiregulin; Antibodies, Blocking; Cell Line; Dipeptides; EGF Family of Proteins; Epithelial Cells; ErbB Receptors; Glycoproteins; Humans; Hydroxamic Acids; Immunoblotting; Intercellular Signaling Peptides and Proteins; Interleukin-8; Kinetics; Metalloproteases; Protease Inhibitors; Quinazolines; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tyrphostins

2006
Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: Animals; Butadienes; Cell Line, Tumor; Chemokine CXCL2; Chemokines; Chymases; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Gene Expression; Humans; Imidazoles; Interleukin-8; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Neutrophils; Nitriles; Peritonitis; Pertussis Toxin; Pyridines; Quinazolines; RNA, Messenger; Serine Endopeptidases

2006
Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp.
    Biochemical pharmacology, 2008, May-15, Volume: 75, Issue:10

    Topics: Adult; Calcium; Cells, Cultured; Dental Pulp; Dinoprostone; Fibrinolysin; Humans; Inflammation; Interleukin-8; Peptides; Pyrroles; Quinazolines; Receptor, PAR-1; RNA, Messenger

2008
MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 294, Issue:6

    Topics: Cell Line; ErbB Receptors; Genes, fos; Humans; Interleukin-8; Matrix Metalloproteinase 12; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Quinazolines; Respiratory Mucosa; Tyrphostins

2008
Corr4A and VRT325 do not reduce the inflammatory response to P. aeruginosa in human cystic fibrosis airway epithelial cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009, Volume: 23, Issue:1-3

    Topics: Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Interleukin-6; Interleukin-8; Piperazines; Pseudomonas Infections; Quinazolines

2009
Naegleria fowleri induces MUC5AC and pro-inflammatory cytokines in human epithelial cells via ROS production and EGFR activation.
    Microbiology (Reading, England), 2009, Volume: 155, Issue:Pt 11

    Topics: Animals; Cell Line; Central Nervous System Protozoal Infections; Dimethyl Sulfoxide; Epithelial Cells; ErbB Receptors; Humans; Immunity, Innate; Interleukin-1beta; Interleukin-8; Male; Mice; Mice, Inbred BALB C; Mucin 5AC; Naegleria fowleri; Neutrophils; Quinazolines; Reactive Oxygen Species; Trophozoites; Tyrphostins

2009
Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells.
    Experimental eye research, 2010, Volume: 91, Issue:3

    Topics: Benzoxazines; Blotting, Western; Capsaicin; Cell Movement; Cell Proliferation; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; ErbB Receptors; Fluorescent Antibody Technique, Indirect; Humans; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Morpholines; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Pyrazoles; Quinazolines; Receptor, Cannabinoid, CB1; Transcriptional Activation; TRPV Cation Channels; Tyrphostins

2010
Irritant activation of epithelial cells is mediated via protease-dependent EGFR activation.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:2

    Topics: Cell Line; Early Growth Response Protein 1; Epithelial Cells; ErbB Receptors; Humans; Interleukin-8; Irritants; Keratinocytes; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Hydrolases; Quinazolines; Signal Transduction; Sodium Dodecyl Sulfate; Vascular Endothelial Growth Factor A

2011
Airway epithelial epidermal growth factor receptor mediates hogbarn dust-induced cytokine release but not Ca2+ response.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:4

    Topics: Air Pollutants, Occupational; Animal Husbandry; Animals; Antibodies, Neutralizing; Bronchi; Calcium; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Dust; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-6; Interleukin-8; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Respiratory Mucosa; Swine; Tyrphostins

2011
Lentivirus-mediated ADAM17 RNA interference inhibited interleukin-8 expression via EGFR signaling in lung epithelial cells.
    Inflammation, 2012, Volume: 35, Issue:3

    Topics: ADAM Proteins; ADAM17 Protein; Antibodies, Neutralizing; Cell Line; Epithelial Cells; ErbB Receptors; Gene Transfer Techniques; Genetic Vectors; Humans; Inflammation; Interleukin-8; Lentivirus; Lipopolysaccharides; Lung; Phosphorylation; Quinazolines; Respiratory Mucosa; RNA Interference; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor alpha; Tyrphostins

2012
Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibition.
    British journal of pharmacology, 2012, Volume: 167, Issue:4

    Topics: 1-Phosphatidylinositol 4-Kinase; Adenine; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Albuterol; Androstadienes; Asthma; Budesonide; Chromones; Dexamethasone; Drug Resistance; Ethanolamines; Female; Fluticasone; Formoterol Fumarate; Humans; Hydrogen Peroxide; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged; Morpholines; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quinazolines; Receptors, Adrenergic, beta-2; Salmeterol Xinafoate; U937 Cells; Young Adult

2012
The EGF receptor and HER2 participate in TNF-α-dependent MAPK activation and IL-8 secretion in intestinal epithelial cells.
    Mediators of inflammation, 2012, Volume: 2012

    Topics: Blotting, Western; Cell Line; Epithelial Cells; ErbB Receptors; HT29 Cells; Humans; Immunoprecipitation; Interleukin-8; Intestines; Mitogen-Activated Protein Kinases; Phosphorylation; Quinazolines; Receptor, ErbB-2; Tumor Necrosis Factor-alpha; Tyrphostins

2012
Plasma RANTES, IL-10, and IL-8 levels in non-small-cell lung cancer patients treated with EGFR-TKIs.
    BMC research notes, 2013, Apr-08, Volume: 6

    Topics: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Chemokine CCL5; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Interleukin-10; Interleukin-8; Lung Neoplasms; Male; Middle Aged; Mutation; Quinazolines; Treatment Outcome

2013
Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine.
    Life sciences, 2013, Nov-19, Volume: 93, Issue:22

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Cell Adhesion; Cell Cycle; Cell Movement; Cell Proliferation; Chemokines; Chemokines, CXC; Chromones; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-8; Morpholines; Pyridines; Quinazolines; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured

2013
Pb²⁺ induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells.
    Environmental toxicology, 2015, Volume: 30, Issue:3

    Topics: Cell Line, Tumor; Environmental Pollutants; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Interleukin-8; Lead; Proto-Oncogene Proteins c-jun; Quinazolines; Stomach Neoplasms; Transcription Factor AP-1; Tyrphostins; Up-Regulation

2015
Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells.
    Journal of translational medicine, 2014, Mar-16, Volume: 12

    Topics: Apoptosis; Betacellulin; Cell Count; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cycloheximide; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lipopolysaccharides; Lung Neoplasms; Models, Biological; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Quinazolines; Receptor Protein-Tyrosine Kinases; Tumor Necrosis Factor-alpha

2014
EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production.
    American journal of physiology. Lung cellular and molecular physiology, 2014, Jul-15, Volume: 307, Issue:2

    Topics: Bronchi; Cell Line; Cell Movement; Chemokine CXCL10; Epithelial Cells; ErbB Receptors; Female; Gefitinib; Humans; Influenza A Virus, H1N1 Subtype; Interferon Regulatory Factor-1; Interleukin-8; Killer Cells, Natural; Quinazolines; Respiratory Syncytial Viruses; Rhinovirus; Signal Transduction; Virus Diseases

2014
Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands.
    Bioorganic & medicinal chemistry letters, 2014, Nov-01, Volume: 24, Issue:21

    Topics: Animals; High-Throughput Screening Assays; Humans; Immunity, Innate; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Ligands; Mice; Models, Molecular; Molecular Structure; NF-kappa B; Quinazolines; Signal Transduction; Structure-Activity Relationship; Toll-Like Receptor 4; Toll-Like Receptors

2014
IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: A549 Cells; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Interleukin-8; Lung Neoplasms; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; p38 Mitogen-Activated Protein Kinases; Phenotype; Quinazolines; Signal Transduction; Up-Regulation

2016
SN38 increases IL-8 expression through the MAPK pathways in HCT8 cells.
    International journal of molecular medicine, 2017, Volume: 39, Issue:1

    Topics: Berberine; Camptothecin; Cell Line, Tumor; Cell Survival; Fluorouracil; Humans; Interleukin-8; Irinotecan; Janus Kinase 2; MAP Kinase Signaling System; Phosphorylation; Quinazolines; Up-Regulation

2017
The Selection of NFκB Inhibitors to Block Inflammation and Induce Sensitisation to FasL-Induced Apoptosis in HNSCC Cell Lines Is Critical for Their Use as a Prospective Cancer Therapy.
    International journal of molecular sciences, 2019, Mar-15, Volume: 20, Issue:6

    Topics: Amides; Anti-Inflammatory Agents; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Fas Ligand Protein; Head and Neck Neoplasms; Humans; Hydrocortisone; Interleukin-8; NF-kappa B; Phenyl Ethers; Pyrimidines; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Tumor Necrosis Factor-alpha

2019
Scratch wound-induced CXCL8 upregulation is EGFR-dependent in keratinocytes.
    Journal of dermatological science, 2020, Volume: 99, Issue:3

    Topics: Cell Movement; Cells, Cultured; ErbB Receptors; Humans; Interleukin-8; Keratinocytes; Quinazolines; Up-Regulation; Wound Healing

2020
Evodiamine Inhibits
    International journal of molecular sciences, 2021, Mar-25, Volume: 22, Issue:7

    Topics: Antigens, Bacterial; Cell Nucleus; Cytokines; Helicobacter Infections; Helicobacter pylori; Humans; Inflammation; Interleukin-8; MAP Kinase Signaling System; Microbial Sensitivity Tests; NF-kappa B; NF-kappa B p50 Subunit; Quinazolines; Signal Transduction; Subcellular Fractions; Type IV Secretion Systems

2021
Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival.
    PloS one, 2021, Volume: 16, Issue:7

    Topics: Cell Survival; Chemokine CCL2; Gene Expression Regulation; Humans; Inflammation; Inflammation Mediators; Influenza A virus; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Lung; Peroxidase; Quinazolines; Reactive Oxygen Species; Superoxides; Tumor Necrosis Factor-alpha

2021